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AR037728A1 - Un compuesto acido 2-hidroxi- o 2-acetiloxi-4-trifluoremetilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero - Google Patents

Un compuesto acido 2-hidroxi- o 2-acetiloxi-4-trifluoremetilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero

Info

Publication number
AR037728A1
AR037728A1 ARP020104736A ARP020104736A AR037728A1 AR 037728 A1 AR037728 A1 AR 037728A1 AR P020104736 A ARP020104736 A AR P020104736A AR P020104736 A ARP020104736 A AR P020104736A AR 037728 A1 AR037728 A1 AR 037728A1
Authority
AR
Argentina
Prior art keywords
hydroxy
prevention
treatment
acid
trifluoremetilbenzoic
Prior art date
Application number
ARP020104736A
Other languages
English (en)
Inventor
Rafanell Julian Garcia
Orti Genis Munoz
Ramirez Jose C Navas
Pulido Jose I Izquierdo
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Publication of AR037728A1 publication Critical patent/AR037728A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere al uso del ácido 2-hidro- o 2-acetiloxi-4-trifluorometilbenzoico, respectivamente, para el tratamiento o prevención del deterioro cognitivo ligero (DCL) en mamíferos, especialmente en seres humanos. Asimismo la presente invención se refiere también al uso del ácido 2-hidroxi o 2-acetiloxi-4-trifluorometilbenzoico, respectivamente, para retrasar o prevenir la conversión de DCL a demencia, especialmente a enfermedad de Alzheimer.
ARP020104736A 2001-12-07 2002-12-06 Un compuesto acido 2-hidroxi- o 2-acetiloxi-4-trifluoremetilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero AR037728A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200102725A ES2190373B1 (es) 2001-12-07 2001-12-07 Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero.

Publications (1)

Publication Number Publication Date
AR037728A1 true AR037728A1 (es) 2004-12-01

Family

ID=8499682

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020104736A AR037728A1 (es) 2001-12-07 2002-12-06 Un compuesto acido 2-hidroxi- o 2-acetiloxi-4-trifluoremetilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero

Country Status (12)

Country Link
US (1) US20030162756A1 (es)
EP (1) EP1453499A1 (es)
JP (1) JP2005515993A (es)
KR (1) KR20050044742A (es)
AR (1) AR037728A1 (es)
AU (1) AU2002352228A1 (es)
BR (1) BR0214779A (es)
CA (1) CA2471794A1 (es)
ES (1) ES2190373B1 (es)
MX (1) MXPA04005450A (es)
NO (1) NO20042785L (es)
WO (1) WO2003047562A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060019938A1 (en) * 2003-12-31 2006-01-26 Beer Tomasz M Estrogen administration for treating male cognitive dysfunction or improving male cognitive function
WO2010134477A1 (ja) * 2009-05-18 2010-11-25 Jsr株式会社 感放射線性樹脂組成物及び化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096252A (en) * 1976-06-10 1978-06-20 J. Uriach & Cia S.A. 4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
US6262042B1 (en) * 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties

Also Published As

Publication number Publication date
JP2005515993A (ja) 2005-06-02
US20030162756A1 (en) 2003-08-28
ES2190373B1 (es) 2004-10-16
NO20042785L (no) 2004-07-01
MXPA04005450A (es) 2005-04-19
CA2471794A1 (en) 2003-06-12
BR0214779A (pt) 2004-11-09
KR20050044742A (ko) 2005-05-12
ES2190373A1 (es) 2003-07-16
WO2003047562A1 (en) 2003-06-12
EP1453499A1 (en) 2004-09-08
AU2002352228A1 (en) 2003-06-17

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