AR037255A1 - Composiciones farmaceuticas que contienen oxibutinina - Google Patents
Composiciones farmaceuticas que contienen oxibutininaInfo
- Publication number
- AR037255A1 AR037255A1 ARP020104230A ARP020104230A AR037255A1 AR 037255 A1 AR037255 A1 AR 037255A1 AR P020104230 A ARP020104230 A AR P020104230A AR P020104230 A ARP020104230 A AR P020104230A AR 037255 A1 AR037255 A1 AR 037255A1
- Authority
- AR
- Argentina
- Prior art keywords
- drug
- oxybutynin
- dosage form
- treatment
- incontinence
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 9
- 229940079593 drug Drugs 0.000 abstract 9
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 abstract 5
- 239000002552 dosage form Substances 0.000 abstract 5
- 229960005434 oxybutynin Drugs 0.000 abstract 5
- 206010021639 Incontinence Diseases 0.000 abstract 2
- 238000013270 controlled release Methods 0.000 abstract 2
- 230000003204 osmotic effect Effects 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se provee una composición farmacéutica y una forma de dosificación para el tratamiento de la incontinencia con oxibutinina y una segunda droga. La segunda droga puede ser cualquier droga para el tratamiento de la incontinencia. Dependiendo de la vía de administración, la forma de dosificación empleada, y la segunda droga que se utilice, la forma de dosificación puede incluir independientemente cantidades terapéuticas o subterapéuticas de oxibutinina y de la segunda droga. Realizaciones particulares incluyen una forma de dosificación que provee una liberación controlada de oxibutinina y de la segunda droga para mantener los niveles terapéuticos efectivos de oxibutinina y/o la segunda droga en un mamífero por un período de tiempo extendido. Se provee un dispositivo osmótico que comprende un núcleo bicapa. El dispositivo osmótico provee una liberación controlada dual de ambas drogas desde el núcleo. Se provee un método para el tratamiento de la incontinencia urinaria (por estrés o urgencia) con una composición farmacéutica y una forma de dosificación. Juntas, la oxibutinina y la segunda droga proveen un beneficio clínico general mejorado con relación a cualquiera de los agentes administrados solos y aproximadamente en la misma dosis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/992,488 US20030185882A1 (en) | 2001-11-06 | 2001-11-06 | Pharmaceutical compositions containing oxybutynin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR037255A1 true AR037255A1 (es) | 2004-11-03 |
Family
ID=25538393
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020104230A AR037255A1 (es) | 2001-11-06 | 2002-11-06 | Composiciones farmaceuticas que contienen oxibutinina |
| ARP020104231A AR037256A1 (es) | 2001-11-06 | 2002-11-06 | Forma de dosificacion de liberacion controlada dual |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020104231A AR037256A1 (es) | 2001-11-06 | 2002-11-06 | Forma de dosificacion de liberacion controlada dual |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20030185882A1 (es) |
| EP (1) | EP1461018A2 (es) |
| AR (2) | AR037255A1 (es) |
| AU (2) | AU2002363361A1 (es) |
| BR (1) | BR0213948A (es) |
| UY (2) | UY27533A1 (es) |
| WO (2) | WO2003039436A2 (es) |
Families Citing this family (39)
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| US8329217B2 (en) | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
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| CA2494233A1 (en) * | 2002-07-29 | 2004-02-05 | Alza Corporation | Formulations and dosage forms for controlled delivery of topiramate |
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| ZA200707250B (en) | 2005-01-27 | 2009-06-24 | Alembic Ltd | Extended release formulation of levetiracetam |
| AU2006261788B2 (en) | 2005-06-27 | 2012-05-31 | Valeant International Bermuda | Modified-release formulations of a bupropion salt |
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| US8871275B2 (en) | 2007-08-08 | 2014-10-28 | Inventia Healthcare Private Limited | Extended release compositions comprising tolterodine |
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| CN102048706B (zh) * | 2011-01-12 | 2012-02-22 | 山东创新药物研发有限公司 | 一种氢溴酸达非那新缓释片及制备方法 |
| CN103156804A (zh) * | 2011-12-13 | 2013-06-19 | 重庆医药工业研究院有限责任公司 | 一种奥昔布宁透皮凝胶及其制备方法 |
| PL2851075T3 (pl) * | 2012-05-14 | 2022-02-21 | Shionogi & Co., Ltd. | Preparat zawierający pochodną 6,7-nienasyconego-7-karbamoilomorfinanu |
| CN103127023B (zh) * | 2013-03-01 | 2014-08-27 | 河北天成药业股份有限公司 | 一种盐酸度洛西汀肠溶片及其制备方法 |
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| GB201708224D0 (en) * | 2017-05-23 | 2017-07-05 | Juniper Pharmaceuticals Uk Ltd | Device |
| LT3746126T (lt) * | 2018-01-30 | 2024-10-25 | Apnimed, Inc. (Delaware) | Miego apnėjos arba paprasto knarkimo gydymui skirti būdai ir kompozicijos |
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-
2001
- 2001-11-06 US US09/992,488 patent/US20030185882A1/en not_active Abandoned
-
2002
- 2002-11-06 UY UY27533A patent/UY27533A1/es not_active Application Discontinuation
- 2002-11-06 EP EP02798241A patent/EP1461018A2/en not_active Withdrawn
- 2002-11-06 AU AU2002363361A patent/AU2002363361A1/en not_active Abandoned
- 2002-11-06 UY UY27532A patent/UY27532A1/es not_active Application Discontinuation
- 2002-11-06 WO PCT/CR2002/000007 patent/WO2003039436A2/es not_active Ceased
- 2002-11-06 WO PCT/CR2002/000006 patent/WO2003039519A2/es not_active Ceased
- 2002-11-06 AR ARP020104230A patent/AR037255A1/es not_active Application Discontinuation
- 2002-11-06 AR ARP020104231A patent/AR037256A1/es not_active Application Discontinuation
- 2002-11-06 BR BR0213948-0A patent/BR0213948A/pt not_active Application Discontinuation
- 2002-11-06 AU AU2002363360A patent/AU2002363360A1/en not_active Abandoned
-
2005
- 2005-12-29 US US11/321,736 patent/US8241667B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| UY27533A1 (es) | 2003-05-30 |
| US8241667B2 (en) | 2012-08-14 |
| WO2003039436A2 (es) | 2003-05-15 |
| WO2003039519A3 (es) | 2004-03-25 |
| US20030185882A1 (en) | 2003-10-02 |
| US20060177510A1 (en) | 2006-08-10 |
| UY27532A1 (es) | 2003-05-30 |
| AR037256A1 (es) | 2004-11-03 |
| WO2003039436A3 (es) | 2004-02-26 |
| AU2002363360A1 (en) | 2003-05-19 |
| BR0213948A (pt) | 2004-08-31 |
| AU2002363361A1 (en) | 2003-05-19 |
| WO2003039519A2 (es) | 2003-05-15 |
| EP1461018A2 (en) | 2004-09-29 |
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