AR036717A1 - Composicion combinada antioxidante y su uso - Google Patents
Composicion combinada antioxidante y su usoInfo
- Publication number
- AR036717A1 AR036717A1 ARP020103715A ARP020103715A AR036717A1 AR 036717 A1 AR036717 A1 AR 036717A1 AR P020103715 A ARP020103715 A AR P020103715A AR P020103715 A ARP020103715 A AR P020103715A AR 036717 A1 AR036717 A1 AR 036717A1
- Authority
- AR
- Argentina
- Prior art keywords
- antioxidant composition
- combined antioxidant
- zwitterion
- carnitine
- acceptable salt
- Prior art date
Links
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 abstract 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- RJFAYQIBOAGBLC-BYPYZUCNSA-N Selenium-L-methionine Chemical compound C[Se]CC[C@H](N)C(O)=O RJFAYQIBOAGBLC-BYPYZUCNSA-N 0.000 abstract 1
- RJFAYQIBOAGBLC-UHFFFAOYSA-N Selenomethionine Natural products C[Se]CCC(N)C(O)=O RJFAYQIBOAGBLC-UHFFFAOYSA-N 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 235000017471 coenzyme Q10 Nutrition 0.000 abstract 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 abstract 1
- 229940110767 coenzyme Q10 Drugs 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 235000019136 lipoic acid Nutrition 0.000 abstract 1
- 230000036542 oxidative stress Effects 0.000 abstract 1
- 229960002718 selenomethionine Drugs 0.000 abstract 1
- 229960002663 thioctic acid Drugs 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición que se puede administrar en forma oral o parenteral que comprende los siguientes componentes: (a) zwitterión de L-carnitina o una sal farmacológicamente aceptable de la misma; (b) zwitterión de acetil L-carnitina o una sal farmacológicamente aceptable de la misma; (c) ácido alfa-lipoico; (d) coenzima Q10; (e) vitamina E; y (f) selenometionina, adecuada para contrarrestar el estrés oxidativo y el uso de la misma.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/968,986 US6923960B2 (en) | 2001-10-03 | 2001-10-03 | Antioxidant combination composition and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036717A1 true AR036717A1 (es) | 2004-09-29 |
Family
ID=25515024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020103715A AR036717A1 (es) | 2001-10-03 | 2002-10-02 | Composicion combinada antioxidante y su uso |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6923960B2 (es) |
| EP (1) | EP1432412A2 (es) |
| CN (1) | CN1809344A (es) |
| AR (1) | AR036717A1 (es) |
| AU (1) | AU2002347614A1 (es) |
| CA (1) | CA2457762A1 (es) |
| WO (1) | WO2003028714A2 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020052402A1 (en) * | 2000-10-31 | 2002-05-02 | Colgate-Palmolive Company | Composition and method |
| DE60030787T2 (de) * | 2000-12-15 | 2007-09-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Verwendung von l-carnitin als stabilitsator für proteine |
| US20040248982A1 (en) * | 2003-06-09 | 2004-12-09 | Dyer Gordon Wayne | Use of compounds for the inhibition of proteins and UV protection |
| US20060110477A1 (en) * | 2004-11-22 | 2006-05-25 | Mccleary Edward L | Composition and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction |
| CN102907561A (zh) * | 2004-12-30 | 2013-02-06 | 希尔氏宠物营养品公司 | 提高老年动物的生活质量的方法 |
| US8252742B2 (en) | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| PL1754478T3 (pl) | 2005-08-04 | 2009-07-31 | Encrypta Gmbh | Ciekła kompozycja zawierająca argininę i kwas α-liponowy, oraz jej zastosowanie do poprawy sprawności seksualnej |
| US8367121B2 (en) * | 2005-11-23 | 2013-02-05 | Florida A & M University | Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease |
| CN101045048B (zh) * | 2006-03-27 | 2011-05-18 | 中国科学院上海生命科学研究院 | 线粒体营养素组合物的应用 |
| WO2008090291A1 (fr) * | 2007-01-17 | 2008-07-31 | Nbc Nutraceutic Business Consulting | Composition dietetique antioxydante a base de fruits et legumes, son procede d'obtention et utilisation de la composition |
| KR100869444B1 (ko) * | 2007-07-11 | 2008-11-18 | 주식회사 중외제약 | 유비데카레논을 함유하는 다층정 비타민 복합제제 |
| WO2009020317A2 (en) * | 2007-08-06 | 2009-02-12 | Biogenics, Inc. | Stabilized antioxidant particles, composition comprising the same and method for preparing the same |
| WO2011143104A1 (en) * | 2010-05-12 | 2011-11-17 | Hill's Pet Nutrition, Inc. | Methods of control and prophylaxis of inflammation and mitigation of inflammatory conditions in companion animals |
| IT1406329B1 (it) * | 2010-12-27 | 2014-02-21 | Istituto Biochimico Naz Savio | Composizione antiossidante per la prevenzione ed il trattamento di patologie ascrivibili al decadimento mitocondriale |
| RU2464816C1 (ru) * | 2011-04-14 | 2012-10-27 | Общество с ограниченной ответственностью "Вилави" | Композиция биологически активных веществ, обладающая геропротекторной активностью, и способ комплексной коррекции возрастных изменений гормонального баланса, функций эпифиза и антиоксидантного статуса, включающий введение указанной композиции |
| US10300101B2 (en) | 2012-09-19 | 2019-05-28 | Quality IP Holdings, LLC | Methods and compositions for enhancing or maintaining fertility |
| US9198889B2 (en) | 2012-09-19 | 2015-12-01 | Quality IP Holdings, LLC | Methods for treating post-traumatic stress disorder |
| US8747922B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods and compositions for increasing sex steroids and growth hormones |
| US8747921B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in humans |
| US10292957B2 (en) | 2012-09-20 | 2019-05-21 | Quality IP Holdings, LLC | Compositions and methods for treating fibromyalgia |
| US9066953B2 (en) | 2012-09-20 | 2015-06-30 | Quality IP Holdings, LLC | Methods for increasing endurance and fat metabolism in humans |
| US8715752B2 (en) | 2012-09-20 | 2014-05-06 | Quality Ip Holdings, Inc. | Compositions for increasing human growth hormone levels |
| US8747923B2 (en) | 2012-09-20 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in canines |
| US8815311B2 (en) * | 2012-09-20 | 2014-08-26 | Quality IP Holdings, LLC | Methods for improving thyroid function in a subject |
| US9138453B2 (en) | 2013-10-14 | 2015-09-22 | Biomarker Pharmaceuticals, Inc. | Nutrient combinations for affecting an aging process |
| US10894072B2 (en) | 2017-02-13 | 2021-01-19 | IP Quality Holdings, LLC | Compositions and methods for treating fibromyalgia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292538A (en) | 1992-07-22 | 1994-03-08 | Metagenics, Inc. | Improved sustained energy and anabolic composition and method of making |
| IT1283967B1 (it) | 1996-03-29 | 1998-05-07 | Sigma Tau Ind Farmaceuti | Uso di l-carnitina o derivati della l-carnitina ed antiossidanti nella prevenzione e trattamento di patologie derivanti da danni ossidativi |
| US5976568A (en) | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
| ES2201467T3 (es) | 1997-03-27 | 2004-03-16 | Michael J. Sole | Composicion nutritiva para la mejora energetica de la celula. |
| US5863940A (en) * | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
| IT1299197B1 (it) | 1998-06-30 | 2000-02-29 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante, antiproliferativa, energetica e atta a migliorare l'utilizzazione metabolica del glucosio. |
| IT1302125B1 (it) | 1998-08-03 | 2000-07-31 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide |
| IT1302307B1 (it) | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
| IT1302863B1 (it) | 1998-11-13 | 2000-10-10 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante e preventiva di alterazionitrombotiche e aterosclerotiche comprendente una carnitina ed un |
| US6479069B1 (en) | 1999-09-23 | 2002-11-12 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
| US6335361B1 (en) | 1999-11-03 | 2002-01-01 | Juvenon Inc. | Method of treating benign forgetfulness |
| US6964969B2 (en) * | 2001-04-19 | 2005-11-15 | Mccleary Edward Larry | Composition and method for treating impaired or deteriorating neurological function |
-
2001
- 2001-10-03 US US09/968,986 patent/US6923960B2/en not_active Expired - Lifetime
-
2002
- 2002-09-26 WO PCT/IT2002/000616 patent/WO2003028714A2/en not_active Ceased
- 2002-09-26 CN CNA028187229A patent/CN1809344A/zh active Pending
- 2002-09-26 AU AU2002347614A patent/AU2002347614A1/en not_active Abandoned
- 2002-09-26 EP EP02783533A patent/EP1432412A2/en not_active Ceased
- 2002-09-26 CA CA002457762A patent/CA2457762A1/en not_active Abandoned
- 2002-10-02 AR ARP020103715A patent/AR036717A1/es not_active Application Discontinuation
-
2005
- 2005-01-11 US US11/032,067 patent/US20050118153A1/en not_active Abandoned
- 2005-04-27 US US11/115,346 patent/US20050186196A1/en not_active Abandoned
- 2005-04-27 US US11/115,141 patent/US20050197280A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002347614A1 (en) | 2003-04-14 |
| US20050197280A1 (en) | 2005-09-08 |
| US20050186196A1 (en) | 2005-08-25 |
| EP1432412A2 (en) | 2004-06-30 |
| WO2003028714A3 (en) | 2004-03-04 |
| CA2457762A1 (en) | 2003-04-10 |
| US20030068309A1 (en) | 2003-04-10 |
| WO2003028714A2 (en) | 2003-04-10 |
| CN1809344A (zh) | 2006-07-26 |
| US6923960B2 (en) | 2005-08-02 |
| US20050118153A1 (en) | 2005-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |