AR035671A1 - ADMINISTRATION OF SEQUENCE OF NUCLEIC ACID TO A FEMALE ANIMAL, TO INCREASE THE GROWTH OF THE DESCENDENCY - Google Patents
ADMINISTRATION OF SEQUENCE OF NUCLEIC ACID TO A FEMALE ANIMAL, TO INCREASE THE GROWTH OF THE DESCENDENCYInfo
- Publication number
- AR035671A1 AR035671A1 ARP010105745A ARP010105745A AR035671A1 AR 035671 A1 AR035671 A1 AR 035671A1 AR P010105745 A ARP010105745 A AR P010105745A AR P010105745 A ARP010105745 A AR P010105745A AR 035671 A1 AR035671 A1 AR 035671A1
- Authority
- AR
- Argentina
- Prior art keywords
- progeny
- vector
- nucleotide sequence
- female animal
- animal
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 239000002773 nucleotide Substances 0.000 abstract 12
- 125000003729 nucleotide group Chemical group 0.000 abstract 12
- 210000004027 cell Anatomy 0.000 abstract 9
- 238000000034 method Methods 0.000 abstract 8
- 108091036066 Three prime untranslated region Proteins 0.000 abstract 7
- 230000035935 pregnancy Effects 0.000 abstract 7
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 102000018997 Growth Hormone Human genes 0.000 abstract 2
- 108010051696 Growth Hormone Proteins 0.000 abstract 2
- 206010062767 Hypophysitis Diseases 0.000 abstract 2
- 102100022831 Somatoliberin Human genes 0.000 abstract 2
- 101710142969 Somatoliberin Proteins 0.000 abstract 2
- 239000000122 growth hormone Substances 0.000 abstract 2
- 239000005556 hormone Substances 0.000 abstract 2
- 229940088597 hormone Drugs 0.000 abstract 2
- 239000008267 milk Substances 0.000 abstract 2
- 210000004080 milk Anatomy 0.000 abstract 2
- 235000013336 milk Nutrition 0.000 abstract 2
- 210000003635 pituitary gland Anatomy 0.000 abstract 2
- 210000001875 somatotroph Anatomy 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Animal Husbandry (AREA)
- Toxicology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se mejora el crecimiento utilizando una metodología potencial de incremento del crecimiento por administración de una secuencia de ácido nucleico tal como GHRH o un análogo, a un animal hembra, preferentemente a través de una ruta de administración parenteral. Los lechones nacidos de cerdas inyectadas con el ADN que codifica GHRH son más grandes y los efectos se demuestran en preneces subsecuentes sin administraciones adicionales del vector. Reivindicación 1: Un método para mejorar o incrementar el crecimiento de una progenie de un animal hembra que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, en donde dicho vector comprende un promotor; una secuencia de nucleótido; y una región no traducida 3', bajo condiciones en donde la secuencia del nucleótido se expresa y en donde dicha introducción y expresión de dicho vector resulta en el mejoramiento o incremento del crecimiento de dicha progenie. Reivindicación 16: Un método para incrementar los niveles de hormona de crecimiento en una progenie de un animal hembra que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, donde dicho vector comprende un promotor, una secuencia de ácido nucleico y una región no traducida 3', bajo condiciones donde la secuencia de nucleótidos se expresa y en donde dicha introducción y expresión de dicho vector resulta en el incremento de los niveles de hormona de crecimiento en dicha progenie. Reivindicación 61: Un método para incrementar la eficacia de alimentos en una progenie de un animal hembra que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, donde dicho vector comprende un promotor; una secuencia de ácido nucleico; y una región no traducida 3', bajo condiciones en donde la secuencia de nucleótido se expresa y en donde dicha introducción y expresión de dicho vector resulta en el incremento de la eficacia alimenticia de dicha progenie. Reivindicación 76: Un método para incrementar la velocidad de crecimiento de una progenie de un animal hembra que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, en donde dicho vector comprende un promotor; una secuencia de nucleótidos; y una región no traducida 3', bajo condiciones en donde la secuencia del nucleótido es expresada y en donde dicha introducción y expresión de dicho vector resulta en el incremento de la velocidad de crecimiento de dicha progenie. Reivindicación 91: Un método para incrementar la relación de somatótrofos respecto de otras células productoras de hormona en una glándula pituitaria de una progenie de un animal hembra que comprende las etapas de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, en donde dicho vector comprende un promotor; una secuencia de nucleótidos; y una región no traducida 3', bajo condiciones donde la secuencia del nucleótido se expresa y en donde dicha introducción y expresión de dicho vector resulta en la relación de somatótrofos respecto de otras células productoras de hormona en la glándula pituitaria de dicha progenie. Reivindicación 107: Un método para retardar el nacimiento de una progenie de un animal que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal hembra previo o durante la gestación de dicha progenie, donde dicho vector comprende un promotor; una secuencia de nucleótidos; y una región no traducida 3', bajo condiciones donde la secuencia del nucleótido se expresa y en donde dicha introducción y expresión de dicho vector resulta en el retraso del nacimiento de dicha progenie. Reivindicación 122: Un método para incrementar la producción de leche en un animal que comprende la etapa de introducir una cantidad efectiva de un vector dentro de las células de dicho animal, donde dicho vector comprende un promotor; una secuencia de nucleótidos; y una región no traducida 3', bajo condiciones donde la secuencia del nucleótido se expresa y en donde dicha introducción y expresión de dicho vector resulta en el incremento de la producción de leche de dicho animal.Growth is enhanced using a potential growth increment methodology by administration of a nucleic acid sequence such as GHRH or an analogue, to a female animal, preferably through a parenteral route of administration. Piglets born from sows injected with the DNA encoding GHRH are larger and the effects are demonstrated in subsequent pregnancies without additional administrations of the vector. Claim 1: A method for improving or increasing the growth of a progeny of a female animal comprising the step of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter; a nucleotide sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in the improvement or increase of the growth of said progeny. Claim 16: A method of increasing the growth hormone levels in a progeny of a female animal comprising the step of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter, a nucleic acid sequence and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in increasing growth hormone levels in said progeny. Claim 61: A method for increasing the efficacy of food in a progeny of a female animal comprising the step of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter; a nucleic acid sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in an increase in the feeding efficiency of said progeny. Claim 76: A method for increasing the growth rate of a progeny of a female animal comprising the step of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter; a nucleotide sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in increasing the growth rate of said progeny. Claim 91: A method for increasing the ratio of somatotrophs to other hormone producing cells in a pituitary gland of a progeny of a female animal comprising the steps of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter; a nucleotide sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in the ratio of somatotrophs to other hormone producing cells in the pituitary gland of said progeny. Claim 107: A method of delaying the birth of a progeny of an animal comprising the step of introducing an effective amount of a vector into the cells of said previous female animal or during the gestation of said progeny, wherein said vector comprises a promoter ; a nucleotide sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in the delay of the birth of said progeny. Claim 122: A method of increasing milk production in an animal comprising the step of introducing an effective amount of a vector into the cells of said animal, wherein said vector comprises a promoter; a nucleotide sequence; and a 3 'untranslated region, under conditions where the nucleotide sequence is expressed and where said introduction and expression of said vector results in increased milk production of said animal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25502100P | 2000-12-12 | 2000-12-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR035671A1 true AR035671A1 (en) | 2004-06-23 |
Family
ID=22966509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010105745A AR035671A1 (en) | 2000-12-12 | 2001-12-11 | ADMINISTRATION OF SEQUENCE OF NUCLEIC ACID TO A FEMALE ANIMAL, TO INCREASE THE GROWTH OF THE DESCENDENCY |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1364004A4 (en) |
| KR (1) | KR20040039187A (en) |
| CN (1) | CN1575301A (en) |
| AR (1) | AR035671A1 (en) |
| AU (1) | AU2002248194B2 (en) |
| BR (1) | BR0116472A (en) |
| CA (1) | CA2430921C (en) |
| MX (1) | MXPA03005236A (en) |
| PL (1) | PL366116A1 (en) |
| WO (1) | WO2002061037A2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003038112A2 (en) | 2001-10-26 | 2003-05-08 | Baylor College Of Medicine | A composition and method to alter lean body mass and bone properties in a subject |
| TW200307749A (en) * | 2002-02-07 | 2003-12-16 | Baylor College Medicine | Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy |
| AR040575A1 (en) * | 2002-07-16 | 2005-04-13 | Advisys Inc | OPTIMIZED SYNTHETIC PLASMIDS IN EXPRESSION CODONS IN MAMMERS |
| DE10240418A1 (en) * | 2002-09-02 | 2004-03-11 | Avontec Gmbh | Formulation for introducing nucleic acids into eukaryotic cells |
| TWI290174B (en) * | 2002-11-04 | 2007-11-21 | Advisys Inc | Synthetic muscle promoters with activities exceeding naturally occurring regulatory sequences in cardiac cells |
| CA2513743C (en) * | 2003-01-28 | 2013-06-25 | Advisys, Inc. | Reducing culling in herd animals growth hormone releasing hormone (ghrh) |
| CN102127545A (en) * | 2010-11-24 | 2011-07-20 | 山东农业大学 | Skeletal muscle specificity CKM (Creatine Kinase Muscle) promoter and applications thereof |
| CN104031930B (en) * | 2014-05-30 | 2017-09-22 | 华南农业大学 | A kind of method of nutrition and immune substance content in raising sow milk |
| CN105219774B (en) * | 2015-10-10 | 2019-04-30 | 广西大学 | Porcine insulin specific expression promoter PIP2 and its application |
| CN105617404A (en) * | 2016-01-27 | 2016-06-01 | 广州市科虎生物技术研究开发中心 | Application of GRF (growth hormone releasing factor) expression plasmid in preparation of medicines for reducing rate of weak piglets |
| DE202018105142U1 (en) * | 2018-04-29 | 2018-10-08 | Kalmarna Limited - CCS Trustees Limited | Compositions for oral administration for influencing the progeny of mammals |
| CN115044666B (en) * | 2022-06-13 | 2024-06-25 | 天津市农业科学院 | A SNP molecular marker for predicting sow second-birth syndrome and its application |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2622455B1 (en) * | 1987-11-04 | 1991-07-12 | Agronomique Inst Nat Rech | APPLICATION OF THE HUMAN GROWTH HORMONE SECRETION STIMULATION FACTOR, ITS ACTIVE FRAGMENTS AND RELATED ANALOGS, TO INCREASE DAIRY PRODUCTION AND NEWBORN WEIGHT IN MAMMALS |
| ZA914983B (en) * | 1990-06-29 | 1992-03-25 | Hoffmann La Roche | His-grf-analogs |
| US6165755A (en) * | 1997-01-23 | 2000-12-26 | University Of Victoria Innovation And Development Corporation | Chicken neuropeptide gene useful for improved poultry production |
| WO1999005300A2 (en) * | 1997-07-24 | 1999-02-04 | Valentis, Inc. | Ghrh expression system and methods of use |
| JP4644402B2 (en) * | 1999-07-26 | 2011-03-02 | ベイラー カレッジ オブ メディスン | Ultra high activity porcine growth hormone releasing hormone analog |
-
2001
- 2001-12-11 AR ARP010105745A patent/AR035671A1/en not_active Application Discontinuation
- 2001-12-12 KR KR10-2003-7007872A patent/KR20040039187A/en not_active Withdrawn
- 2001-12-12 AU AU2002248194A patent/AU2002248194B2/en not_active Expired
- 2001-12-12 WO PCT/US2001/048726 patent/WO2002061037A2/en not_active Ceased
- 2001-12-12 PL PL01366116A patent/PL366116A1/en not_active Application Discontinuation
- 2001-12-12 CA CA2430921A patent/CA2430921C/en not_active Expired - Lifetime
- 2001-12-12 BR BR0116472-4A patent/BR0116472A/en not_active IP Right Cessation
- 2001-12-12 MX MXPA03005236A patent/MXPA03005236A/en not_active Application Discontinuation
- 2001-12-12 CN CNA018220088A patent/CN1575301A/en active Pending
- 2001-12-12 EP EP01997073A patent/EP1364004A4/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN1575301A (en) | 2005-02-02 |
| CA2430921C (en) | 2016-06-07 |
| WO2002061037A2 (en) | 2002-08-08 |
| AU2002248194B2 (en) | 2007-04-05 |
| BR0116472A (en) | 2005-04-05 |
| EP1364004A4 (en) | 2005-11-09 |
| WO2002061037B1 (en) | 2004-01-15 |
| KR20040039187A (en) | 2004-05-10 |
| PL366116A1 (en) | 2005-01-24 |
| MXPA03005236A (en) | 2005-04-08 |
| CA2430921A1 (en) | 2002-08-08 |
| WO2002061037A3 (en) | 2003-10-02 |
| EP1364004A2 (en) | 2003-11-26 |
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