AR034429A1 - Uso de una composicion que contiene un anticuerpo anti-tnf alfa en la fabricacion de un medicamento y equipo y jeringa cargada, conteniendo dicha composicion. - Google Patents
Uso de una composicion que contiene un anticuerpo anti-tnf alfa en la fabricacion de un medicamento y equipo y jeringa cargada, conteniendo dicha composicion.Info
- Publication number
- AR034429A1 AR034429A1 ARP020102143A ARP020102143A AR034429A1 AR 034429 A1 AR034429 A1 AR 034429A1 AR P020102143 A ARP020102143 A AR P020102143A AR P020102143 A ARP020102143 A AR P020102143A AR 034429 A1 AR034429 A1 AR 034429A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- tnf alpha
- manufacture
- alpha antibody
- antibodies
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 101000611183 Homo sapiens Tumor necrosis factor Proteins 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 102000057041 human TNF Human genes 0.000 abstract 1
- 229960000485 methotrexate Drugs 0.000 abstract 1
- 239000007929 subcutaneous injection Substances 0.000 abstract 1
- 238000010254 subcutaneous injection Methods 0.000 abstract 1
Classifications
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Molecular Biology (AREA)
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- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
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Abstract
Uso de una composición que contiene un anticuerpo anti-TNF alfa o una porción de unión a antígeno del mismo en la fabricación de un medicamento que se usa en un régimen de dosificación cada dos semanas para tratar un trastorno tratable con un anticuerpo anti-TNF alfa, en un sujeto humano. Esta composición puede además comprender metotrexato conjuntos de elementos (kits) que contienen una composición farmacéutica e instrucciones para su dosificación, y jeringas cargadas que contienen composiciones farmacéuticas. Este medicamento es utilizado para tratar desordenes en donde la actividad de TNF alfa es perjudicial mediante la administración cada dos semanas de inyecciones subcutáneas de anticuerpos a un sujeto donde los anticuerpos preferiblemente son anticuerpos recombinantes humanos que se unen específicamente a TNF alfa humano.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29696101P | 2001-06-08 | 2001-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR034429A1 true AR034429A1 (es) | 2004-02-25 |
Family
ID=23144283
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020102143A AR034429A1 (es) | 2001-06-08 | 2002-06-07 | Uso de una composicion que contiene un anticuerpo anti-tnf alfa en la fabricacion de un medicamento y equipo y jeringa cargada, conteniendo dicha composicion. |
| ARP100102560A AR077572A2 (es) | 2001-06-08 | 2010-07-14 | Uso de una composicion que contiene un anticuerpo anti-tnf alfa en la fabricacion de un medicamento y equipo y jeringa cargada conteniendo dicha composicion |
| ARP130100511A AR090099A2 (es) | 2001-06-08 | 2013-02-19 | USO DE UNA COMPOSICION QUE CONTIENE UN ANTICUERPO ANTI-TNFa EN LA FABRICACION DE UN MEDICAMENTO Y EQUIPO Y JERINGA CARGADA, CONTENIENDO DICHA COMPOSICION |
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| ARP130100511A AR090099A2 (es) | 2001-06-08 | 2013-02-19 | USO DE UNA COMPOSICION QUE CONTIENE UN ANTICUERPO ANTI-TNFa EN LA FABRICACION DE UN MEDICAMENTO Y EQUIPO Y JERINGA CARGADA, CONTENIENDO DICHA COMPOSICION |
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2015
- 2015-02-27 US US14/634,478 patent/US20150175691A1/en not_active Abandoned
- 2015-02-27 US US14/634,530 patent/US20150165023A1/en not_active Abandoned
- 2015-05-18 US US14/715,310 patent/US20150246968A1/en not_active Abandoned
- 2015-06-19 JP JP2015123695A patent/JP6074462B2/ja not_active Expired - Lifetime
-
2016
- 2016-06-10 US US15/179,803 patent/US9546212B2/en not_active Expired - Fee Related
- 2016-11-01 JP JP2016214315A patent/JP6302529B2/ja not_active Expired - Lifetime
-
2017
- 2017-02-08 CY CY20171100183T patent/CY1120540T1/el unknown
-
2020
- 2020-02-07 US US16/784,621 patent/US20200181252A1/en not_active Abandoned
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