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AR020927A1 - Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica dotada de efecto antitumoral - Google Patents

Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica dotada de efecto antitumoral

Info

Publication number
AR020927A1
AR020927A1 ARP990105316A ARP990105316A AR020927A1 AR 020927 A1 AR020927 A1 AR 020927A1 AR P990105316 A ARP990105316 A AR P990105316A AR P990105316 A ARP990105316 A AR P990105316A AR 020927 A1 AR020927 A1 AR 020927A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
composition containing
dna fragments
antigen protein
coding dna
Prior art date
Application number
ARP990105316A
Other languages
English (en)
Original Assignee
Menarini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa
Publication of AR020927A1 publication Critical patent/AR020927A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se provee una composicion farmacéutica que contiene uno o varias moléculas de ADN que codifica fragmentos de una proteína sobreexpresada en célulastumorales, con el fin de inducir una respuesta inmunologica específica de Ag antitumoral, enasociacion con excipientes y adyuvantes adecuados.
ARP990105316A 1998-10-30 1999-10-21 Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica dotada de efecto antitumoral AR020927A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.

Publications (1)

Publication Number Publication Date
AR020927A1 true AR020927A1 (es) 2002-06-05

Family

ID=11380969

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105316A AR020927A1 (es) 1998-10-30 1999-10-21 Composicion farmaceutica que contiene fragmentos de adn codificador de una proteina antigenica dotada de efecto antitumoral

Country Status (19)

Country Link
EP (1) EP1124956A2 (es)
JP (1) JP2002528519A (es)
CN (1) CN1324406A (es)
AR (1) AR020927A1 (es)
AU (1) AU1152200A (es)
BG (1) BG105458A (es)
BR (1) BR9914892A (es)
CA (1) CA2348745A1 (es)
CO (1) CO5231134A1 (es)
CZ (1) CZ20011521A3 (es)
EA (1) EA200100395A1 (es)
HU (1) HUP0103784A2 (es)
IT (1) IT1303683B1 (es)
MX (1) MXPA01004186A (es)
PE (1) PE20001287A1 (es)
PL (1) PL348156A1 (es)
SK (1) SK5712001A3 (es)
TR (1) TR200101141T2 (es)
WO (1) WO2000025827A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
EP1257565A4 (en) * 2000-02-01 2005-04-06 Austin Research Inst DERIVED FROM MUCIN-1 ANTIGENE AND ITS USE IN IMMUNOTHERAPY
CN1455680A (zh) * 2000-09-11 2003-11-12 达纳-法伯癌症协会有限公司 Muc1胞外域和癌症治疗组合物及方法
EP1958642A1 (en) 2000-12-22 2008-08-20 Dana-Farber Cancer Institute Regulation of cell growth by MUC1
KR101199789B1 (ko) * 2003-03-24 2012-11-09 더 스크립스 리서치 인스티튜트 종양 성장 억제 ｄｎａ 백신
US7696306B2 (en) 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
WO2005042573A1 (en) * 2003-10-24 2005-05-12 Dana-Farber Cancer Institute, Inc. Modulation of the interaction of muc1 with muc1 ligands
US7871784B2 (en) 2007-02-02 2011-01-18 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins
WO2008097840A2 (en) 2007-02-02 2008-08-14 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of muc1 by hsf1 and stat3
CN106279435B (zh) * 2016-08-16 2019-06-07 新乡医学院 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用
CN113321724B (zh) * 2021-03-24 2022-02-01 深圳市新靶向生物科技有限公司 一种与食道癌驱动基因突变相关的抗原肽及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262545B (it) * 1993-10-25 1996-07-02 Menarini Ricerche Sud S P A A Sistema di espressione per linee cellulari eucariotiche
WO1998037095A2 (en) * 1997-02-24 1998-08-27 Therion Biologics Corporation Recombinant pox virus for immunization against muc1 tumor-associated antigen

Also Published As

Publication number Publication date
PL348156A1 (en) 2002-05-06
WO2000025827A2 (en) 2000-05-11
PE20001287A1 (es) 2000-12-07
ITMI982330A0 (it) 1998-10-30
WO2000025827A3 (en) 2000-08-10
EP1124956A2 (en) 2001-08-22
BG105458A (en) 2002-06-28
CA2348745A1 (en) 2000-05-11
IT1303683B1 (it) 2001-02-23
CZ20011521A3 (cs) 2001-10-17
JP2002528519A (ja) 2002-09-03
TR200101141T2 (tr) 2001-09-21
ITMI982330A1 (it) 2000-04-30
CN1324406A (zh) 2001-11-28
MXPA01004186A (es) 2002-06-04
BR9914892A (pt) 2001-07-17
HUP0103784A2 (hu) 2002-02-28
AU1152200A (en) 2000-05-22
EA200100395A1 (ru) 2001-10-22
SK5712001A3 (en) 2002-04-04
CO5231134A1 (es) 2002-12-27

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