[go: up one dir, main page]

AR020226A1 - Compuestos para la inhibicion de la secrecion de acido gastrico, procesos para su preparacion, formulaciones farmaceuticas y uso de dichos compuestos parapreparar medicamentos - Google Patents

Compuestos para la inhibicion de la secrecion de acido gastrico, procesos para su preparacion, formulaciones farmaceuticas y uso de dichos compuestos parapreparar medicamentos

Info

Publication number
AR020226A1
AR020226A1 ARP990104163A ARP990104163A AR020226A1 AR 020226 A1 AR020226 A1 AR 020226A1 AR P990104163 A ARP990104163 A AR P990104163A AR P990104163 A ARP990104163 A AR P990104163A AR 020226 A1 AR020226 A1 AR 020226A1
Authority
AR
Argentina
Prior art keywords
compounds
processes
preparation
pharmaceutical formulations
gastric acid
Prior art date
Application number
ARP990104163A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR020226A1 publication Critical patent/AR020226A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Compuestos y sales terapéuticamente efectivas de los mismos, de la formula (I), donde los sustituyentes R1 a R4, X y Ar tienen los significados que constanen la descripcion, que inhiben la secrecion de ácido gástrico en forma exogena o endogena, y que por lo tanto pueden usarse en la prevencion y tratamiento deenfermedades inflamatorias gastrointestinales, procesos para su preparacion, formulaciones farmacéuticas y uso de dichos compuestos para preparar medicamentos.
ARP990104163A 1998-08-21 1999-08-19 Compuestos para la inhibicion de la secrecion de acido gastrico, procesos para su preparacion, formulaciones farmaceuticas y uso de dichos compuestos parapreparar medicamentos AR020226A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9802794A SE9802794D0 (sv) 1998-08-21 1998-08-21 New compounds

Publications (1)

Publication Number Publication Date
AR020226A1 true AR020226A1 (es) 2002-05-02

Family

ID=20412307

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990104163A AR020226A1 (es) 1998-08-21 1999-08-19 Compuestos para la inhibicion de la secrecion de acido gastrico, procesos para su preparacion, formulaciones farmaceuticas y uso de dichos compuestos parapreparar medicamentos

Country Status (20)

Country Link
US (3) US6579884B1 (es)
EP (2) EP1105391B1 (es)
JP (1) JP2002523415A (es)
KR (1) KR20010072798A (es)
CN (1) CN1329613A (es)
AR (1) AR020226A1 (es)
AT (1) ATE280768T1 (es)
AU (1) AU5767999A (es)
BR (1) BR9913103A (es)
CA (1) CA2339286A1 (es)
DE (1) DE69921483T2 (es)
DK (1) DK1105391T3 (es)
ES (1) ES2229763T3 (es)
IL (1) IL141166A0 (es)
NO (1) NO20010860L (es)
PT (1) PT1105391E (es)
SE (1) SE9802794D0 (es)
SI (1) SI1105391T1 (es)
WO (1) WO2000011000A2 (es)
ZA (1) ZA200100913B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
WO2004026867A2 (en) * 2002-09-19 2004-04-01 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
ATE382048T1 (de) * 2002-09-19 2008-01-15 Schering Corp Pyrazolopyrimdine als hemmstoffe cyclin abhängiger kinasen
BRPI0406427B8 (pt) 2003-03-10 2021-05-25 Astrazeneca Ab processo para a preparação de roflumilast
SE0301904D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8536492B2 (en) * 2003-10-27 2013-09-17 Applied Materials, Inc. Processing multilayer semiconductors with multiple heat sources
AU2004285394B2 (en) 2003-11-03 2009-01-08 Astrazeneca Ab Imidazo (1,2-A) pyridine derivatives for the treatment of silent gastro-esophageal reflux
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
EP1787991B2 (en) * 2004-07-28 2020-06-24 Takeda Pharmaceutical Company Limited PYRROLO[2,3-c]PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE
WO2006097456A1 (en) * 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2008065199A1 (en) * 2006-12-01 2008-06-05 Galapagos N.V. Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases
EP2573080A1 (en) * 2007-09-27 2013-03-27 The United States of America, as Represented by the Secretary, Department of Health and Human Services Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
CN111606846A (zh) * 2020-05-12 2020-09-01 广州理文科技有限公司 一种n`-三氟甲磺酰基n杂芳香胺类化合物及其制备方法
KR102902555B1 (ko) * 2023-09-15 2025-12-24 (주)휴온스 신규한 이미다조피리딘계 화합물 및 이를 유효성분으로 포함하는 위장관 염증질환 또는 위산-관련 질환의 예방, 개선 또는 치료용 조성물
WO2025058459A1 (ko) * 2023-09-15 2025-03-20 (주)휴온스 신규한 이미다조피리딘계 화합물 및 이를 유효성분으로 포함하는 위장관 염증질환 또는 위산-관련 질환의 예방, 개선 또는 치료용 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ES2167362T3 (es) 1993-04-22 2002-05-16 Byk Gulden Lomberg Chem Fab Sales de piridinio y su utilizacion para combatir a bacterias helicobacter.
UA48122C2 (uk) 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
NZ290818A (en) 1994-07-28 1998-10-28 Byk Gulden Lomberg Chem Fab Benzyl-imidazopyridines
NZ290819A (en) 1994-07-28 1998-06-26 Byk Gulden Lomberg Chem Fab Acyl 8-benzyloxy- or 8-benzylaminoimidazopyridines
JPH10505333A (ja) 1994-07-28 1998-05-26 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング イミダゾピリジン−アゾリジノン
AU3221795A (en) * 1994-07-28 1996-02-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Halogenated imidazopyridines
ATE294802T1 (de) * 1996-01-26 2005-05-15 Altana Pharma Ag 3-alkylimidazopyridine
DE19602853A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue Halogenimidazopyridine
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE9802793D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds

Also Published As

Publication number Publication date
JP2002523415A (ja) 2002-07-30
EP1105391B1 (en) 2004-10-27
US20050154007A1 (en) 2005-07-14
SI1105391T1 (en) 2005-02-28
CN1329613A (zh) 2002-01-02
DE69921483D1 (de) 2004-12-02
BR9913103A (pt) 2001-05-08
AU5767999A (en) 2000-03-14
US20030220364A1 (en) 2003-11-27
ATE280768T1 (de) 2004-11-15
NO20010860D0 (no) 2001-02-20
EP1411056A3 (en) 2004-04-28
DE69921483T2 (de) 2006-02-02
WO2000011000A2 (en) 2000-03-02
IL141166A0 (en) 2002-02-10
PT1105391E (pt) 2005-01-31
NO20010860L (no) 2001-04-23
DK1105391T3 (da) 2005-01-24
US6579884B1 (en) 2003-06-17
EP1411056A2 (en) 2004-04-21
KR20010072798A (ko) 2001-07-31
ZA200100913B (en) 2002-05-02
US6790960B2 (en) 2004-09-14
ES2229763T3 (es) 2005-04-16
SE9802794D0 (sv) 1998-08-21
EP1105391A2 (en) 2001-06-13
WO2000011000A3 (en) 2000-06-15
CA2339286A1 (en) 2000-03-02

Similar Documents

Publication Publication Date Title
AR020226A1 (es) Compuestos para la inhibicion de la secrecion de acido gastrico, procesos para su preparacion, formulaciones farmaceuticas y uso de dichos compuestos parapreparar medicamentos
BR9814755A (pt) Composto, formulação farmacêutica, uso de um composto, e, processos para a preparação de um composto, para inibir a secreção do ácido gástrico, para o tratamento de doenças inflamatórias gastrointestinais, e para o tratamento ou profilaxia de condições que envolvam infecção por helicobacter pylori da mucosa gástrica humana
AR015768A1 (es) DERIVADOS DE IMIDAZO PIRIDINA QUE INHIBEN LA SECRECIoN DE ÁCIDO GÁSTRICO, COMPOSICIoN FARMACÉUTICA, PROCEDIMIENTOS PARA SU PREPARACIoN, FORMULACIoN FARMACÉUTICA, USO DE DICHOS DERIVADOS PARA PREPARAR MEDICAMENTOS Y COMPUESTOS INTERMEDIARIOS uTILES EN EL PROCEDIMIENTO PARA LA PREPARACIoN DE DICHOS DE
BR9406979A (pt) Composto,composicão farmaceutica para tratar uma doenca inflamatória suscetivel de tratamento com um agente anti- inflamatório nao esteroidal processos para tratar uma doenca inflamatória e para preparar um composto sal famacéuticamente aceitável uso de um composto composicão farmaceutica anti-inflamatória nao esteroidal
ES2150489T3 (es) 1-amidinofenil-pirrolidonas, -piperidinonas, -azetinonas como inhibidores de la agregacion de plaquetas.
ES2076935T3 (es) Compuesto de pirazolopiridina y procedimientos para su preparacion.
AR011134A1 (es) Derivados de imidazo piridina substituidos para la inhibicion de la secrecion de acido gastrico; una sal del mismo, procedimiento para su preparacion, formulacion farmaceutica que los contiene y el uso de dicho compuesto para la manufactura de un medicamento
FR2356424A1 (fr) Compositions pharmaceutiques a base d'acide phophono-formique utiles pour lutter contre les infections virales
MX9307779A (es) Compuestos benzoicos fundidos.
IL107157A0 (en) Immunopotentiatory agents and pharmaceutical compositions comprising them
DK1313697T3 (da) Immunregulatoriske forbindelser, derivater deraf samt anvendelse deraf
AR020225A1 (es) Compuestos, productos que los contienen, procesos para su preparacion, formulaciones farmaceuticas, y usos de dichos compuestos
PT1396270E (pt) Processo para a preparacao de compostos uteisncomo intermidiarios.
MY128014A (en) Thiol and thiocarbonyl derivatives which are useful as carboxypeptidase u inhibitors
PT97395A (pt) Processo para a preparacao de 2,9-di-substituidas-4h-pirido{1,2-a}-pirimidin-4-onas e de composicoes farmaceuticas que os contem
NO20050573L (no) 4-'7-halo-2-quino (XA) linyloksy ! fenoksypropionsyrederivater som antineoplastiske midler
NO912414D0 (no) Forbindelse med mavesyreinhiberende effekt og fremgangsmaate for dens fremstilling.
CA2244134A1 (en) Diphenyl stilbenes as prodrugs to cox-2 inhibitors
JPS56115793A (en) Phosphonohydroxyacetic acid* its salt* their manufacture and drug thereof as active component
SE9901572D0 (sv) New compounds
ES2179526T3 (es) Analogos y profarmacos del paclitaxel solubles en agua.
CO5261624A1 (es) Novedosos derivados fenilheteroalquilamina, procesos para su preparacion, composiciones farmaceuticas que comprenden dichos derivados novedosos y su uso en terapia
ATE325809T1 (de) Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure
AR011178A1 (es) Compuesto de sal de sodio de (acido (e) 4,6-dicloro-3-(2-oxo-1- fenilpirrolidin-3-ilideno-metil)-1h-indol-2-carboxilico en su forma hidratada,proceso para su preparacion, composicion farmaceutica que lo contiene y metodo de tratamiento utilizando dicho compuesto
AR030945A1 (es) Amidas de acido fenilciclohexanocarboxilico sustituido y su uso