AR029546A1 - Particulas farmaceuticas con sabor enmascarado - Google Patents
Particulas farmaceuticas con sabor enmascaradoInfo
- Publication number
- AR029546A1 AR029546A1 ARP010103130A ARP010103130A AR029546A1 AR 029546 A1 AR029546 A1 AR 029546A1 AR P010103130 A ARP010103130 A AR P010103130A AR P010103130 A ARP010103130 A AR P010103130A AR 029546 A1 AR029546 A1 AR 029546A1
- Authority
- AR
- Argentina
- Prior art keywords
- active ingredient
- masked
- pharmaceutical particles
- chewable tablets
- masked flavor
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 239000000796 flavoring agent Substances 0.000 title 1
- 235000019634 flavors Nutrition 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000007910 chewable tablet Substances 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen partículas con sabor enmascarado y tabletas masticables preparadas con las mismas. Las partículas con sabor enmascarado comprenden un nucleo que contiene un ingrediente activo y un revestimiento polimérico que recubre dicho nucleo, donde dicho revestimiento comprende una mezcla de: a) un polímero entérico y b) un polímero insoluble formador de película y donde la superficie de dicha partícula está libre del ingrediente activo. Las tabletas masticables producen la liberacion inmediata del ingrediente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21550500P | 2000-06-30 | 2000-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029546A1 true AR029546A1 (es) | 2003-07-02 |
Family
ID=22803235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010103130A AR029546A1 (es) | 2000-06-30 | 2001-06-29 | Particulas farmaceuticas con sabor enmascarado |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7223421B2 (es) |
| EP (1) | EP1166777B1 (es) |
| JP (1) | JP2002087952A (es) |
| KR (1) | KR20020002321A (es) |
| CN (1) | CN1356102A (es) |
| AR (1) | AR029546A1 (es) |
| AT (1) | ATE404180T1 (es) |
| AU (1) | AU784613B2 (es) |
| BR (1) | BR0103033A (es) |
| CA (1) | CA2351814C (es) |
| CO (1) | CO5271674A1 (es) |
| DE (1) | DE60135273D1 (es) |
| ES (1) | ES2311500T3 (es) |
| MX (1) | MXPA01006803A (es) |
| NZ (1) | NZ512683A (es) |
| SA (1) | SA01220402B1 (es) |
| ZA (1) | ZA200105407B (es) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2314893C (en) | 1997-12-22 | 2005-09-13 | Euro-Celtique, S.A. | Opioid agonist/antagonist combinations |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| US20020119196A1 (en) * | 2000-12-21 | 2002-08-29 | Narendra Parikh | Texture masked particles containing an active ingredient |
| US8268333B2 (en) | 2001-04-24 | 2012-09-18 | Lintec Corporation | Orally administered agent and an orally administered agent/supporting substrate complex |
| ATE493130T1 (de) | 2001-05-11 | 2011-01-15 | Endo Pharmaceuticals Inc | Opioid enthaltende arzneiform gegen missbrauch |
| US20040253312A1 (en) * | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
| BR0308927A (pt) * | 2002-04-04 | 2005-01-04 | Pfizer Prod Inc | Comprimido mastigável de sabor agradável |
| DE17154462T1 (de) | 2002-04-05 | 2019-12-19 | Euro-Celtique S.A. | Matrix für nachhaltige, invariante und unabhängige freisetzung von wirkstoffverbindungen |
| US8092831B2 (en) * | 2002-11-08 | 2012-01-10 | Andrx Pharmaceuticals, Llc | Antihistamine and decongestant system |
| US20040258752A1 (en) * | 2003-01-31 | 2004-12-23 | Paruthi Manoj Kumar | Taste masking pharmaceutical composition and process for its preparation |
| US20040186180A1 (en) * | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
| US20040213838A1 (en) * | 2003-04-24 | 2004-10-28 | Mazer Terrence B. | Medical food tablets containing free amino acids |
| US20060124695A1 (en) * | 2003-06-27 | 2006-06-15 | Wakunaga Pharmaceutical Co., Ltd. | Stable liquid preparation |
| US20040265372A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
| US20040265373A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
| JP3881640B2 (ja) * | 2003-08-08 | 2007-02-14 | 塩野義製薬株式会社 | ロラタジンを含むドライシロップ剤 |
| US7282217B1 (en) | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
| US20050095299A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
| US20050095300A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
| US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
| US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
| US8062659B2 (en) | 2004-02-20 | 2011-11-22 | Novartis Ag | Dietary fiber composition |
| US20050186271A1 (en) * | 2004-02-24 | 2005-08-25 | Sheskey Paul J. | Process for dispersing a fluid in a mass of solid particles |
| EP1604666A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD) |
| EP1604667A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the restless leg syndrome |
| ITMI20042356A1 (it) * | 2004-12-10 | 2005-03-10 | Acraf | Composizione farmaceutica orodisperdibile e procedimento per prepararla |
| AP2274A (en) * | 2005-01-28 | 2011-08-19 | Euro Celtiques Sa | Alcohol resistant dosage forms. |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| EP1695700A1 (en) * | 2005-02-28 | 2006-08-30 | Euro-Celtique S.A. | Dosage form containing oxycodone and naloxone |
| EP1813276A1 (en) * | 2006-01-27 | 2007-08-01 | Euro-Celtique S.A. | Tamper resistant dosage forms |
| WO2007123153A1 (ja) * | 2006-04-19 | 2007-11-01 | Ono Pharmaceutical Co., Ltd. | 経口投与用カプセル |
| US20070264335A1 (en) * | 2006-05-09 | 2007-11-15 | Sherman Bernard C | Modified release tablets comprising tramadol |
| US20100297226A1 (en) * | 2006-06-01 | 2010-11-25 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
| US20080031927A1 (en) * | 2006-07-11 | 2008-02-07 | Catani Steven J | Solid oral dosage vitamin and mineral compositions |
| WO2008052033A2 (en) * | 2006-10-25 | 2008-05-02 | Mcneil-Ppc, Inc. | Ibuprofen composition |
| FR2930147B1 (fr) * | 2008-04-18 | 2013-02-08 | Flamel Tech Sa | Forme orale solide dotee d'un double profil de liberation |
| JP5406288B2 (ja) * | 2008-07-07 | 2014-02-05 | ユーロ−セルティーク エス.エイ. | 尿閉を治療するためのオピオイド拮抗薬の使用 |
| ME03298B (me) | 2009-03-10 | 2019-07-20 | Euro Celtique Sa | Farmaceutske kombinacije sa trenutnim oslobađanjem које obuhvataju oksikodon i nalokson |
| US20100239681A1 (en) * | 2009-03-20 | 2010-09-23 | Biokey, Inc. | Controlled Release Particulates Containing Water-Insoluble Drug |
| CN104258408B (zh) * | 2010-03-31 | 2017-10-03 | 持田制药株式会社 | 易服用性固体制剂 |
| CA2847614C (en) | 2011-09-30 | 2018-10-23 | Mochida Pharmaceutical Co., Ltd. | Easily dosable solid preparation |
| FR2999426B1 (fr) * | 2012-12-13 | 2015-01-02 | Flamel Tech Sa | Forme orale multiparticulaire a liberation immediate d'au moins un compose actif, comprenant des particules enrobees resistantes au broyage. |
| JP5836980B2 (ja) * | 2013-01-11 | 2015-12-24 | 信越化学工業株式会社 | 薬物含有粒子、固形製剤及び薬物含有粒子の製造方法 |
| JP2016525138A (ja) | 2013-07-23 | 2016-08-22 | ユーロ−セルティーク エス.エイ. | 疼痛および腸内ディスバイオシスをもたらす疾患および/または腸内細菌移行に対するリスクを高める疾患に罹患している患者における痛みの治療への使用のためのオキシコドンおよびナロキソンの組み合わせ |
| EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| CN112674348A (zh) * | 2020-12-23 | 2021-04-20 | 石药集团中诺药业(泰州)有限公司 | 一种b族维生素含片和咀嚼片制备方法 |
| AU2023311967A1 (en) * | 2022-07-19 | 2025-02-06 | Pinata Holdings Inc. | Inhalable serotonin receptor agonist formulations |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS48103718A (es) | 1972-04-14 | 1973-12-26 | ||
| US4160827A (en) * | 1978-02-06 | 1979-07-10 | The Upjohn Company | Metronidazole phosphate and salts |
| JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
| JPS57120518A (en) * | 1981-01-19 | 1982-07-27 | Tanabe Seiyaku Co Ltd | Preparation of microcapsule |
| US4749575A (en) * | 1983-10-03 | 1988-06-07 | Bio-Dar Ltd. | Microencapsulated medicament in sweet matrix |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4971791A (en) * | 1985-08-26 | 1990-11-20 | The Procter & Gamble Company | Taste masking compositions |
| US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
| US4916161A (en) * | 1988-10-25 | 1990-04-10 | Bristol-Myers Squibb | Taste-masking pharmaceutical agents |
| US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
| CA2063141C (en) * | 1989-08-04 | 1997-03-04 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
| IT1246383B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per il mascheramento del sapore di farmaci |
| FI922107A0 (fi) | 1991-05-10 | 1992-05-08 | Faulding F H & Co Ltd | Mikrokapselkomposition och foerfarande. |
| US5837277A (en) * | 1992-06-04 | 1998-11-17 | Smithkline Beecham Corporation | Palatable pharmaceutical compositions |
| ES2149250T3 (es) * | 1993-04-23 | 2000-11-01 | Novartis Ag | Dispositivo para la administracion de medicamentos con liberacion controlada. |
| ZA945944B (en) * | 1993-08-13 | 1996-02-08 | Eurand America Inc | Procedure for encapsulating nsaids |
| GB9317897D0 (en) * | 1993-08-27 | 1993-10-13 | Plessey Telecomm | Telecommunications switching element |
| JPH07223970A (ja) * | 1994-02-10 | 1995-08-22 | Tanabe Seiyaku Co Ltd | 消化管内適所放出製剤 |
| US5536507A (en) * | 1994-06-24 | 1996-07-16 | Bristol-Myers Squibb Company | Colonic drug delivery system |
| JP3355593B2 (ja) * | 1994-08-19 | 2002-12-09 | 信越化学工業株式会社 | 固形腸溶製剤の製造方法 |
| CA2266629C (en) * | 1996-10-01 | 2002-04-16 | Cima Labs Inc. | Taste-masked microcapsule compositions and methods of manufacture |
| US6046177A (en) * | 1997-05-05 | 2000-04-04 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations |
-
2001
- 2001-06-08 US US09/878,034 patent/US7223421B2/en not_active Expired - Lifetime
- 2001-06-28 CA CA002351814A patent/CA2351814C/en not_active Expired - Fee Related
- 2001-06-29 KR KR1020010038206A patent/KR20020002321A/ko not_active Ceased
- 2001-06-29 CN CN01123387A patent/CN1356102A/zh active Pending
- 2001-06-29 ES ES01305664T patent/ES2311500T3/es not_active Expired - Lifetime
- 2001-06-29 AR ARP010103130A patent/AR029546A1/es unknown
- 2001-06-29 EP EP01305664A patent/EP1166777B1/en not_active Expired - Lifetime
- 2001-06-29 AT AT01305664T patent/ATE404180T1/de not_active IP Right Cessation
- 2001-06-29 DE DE60135273T patent/DE60135273D1/de not_active Expired - Lifetime
- 2001-06-29 ZA ZA200105407A patent/ZA200105407B/xx unknown
- 2001-06-29 NZ NZ512683A patent/NZ512683A/xx unknown
- 2001-06-29 AU AU54158/01A patent/AU784613B2/en not_active Ceased
- 2001-07-02 BR BR0103033-7A patent/BR0103033A/pt not_active Application Discontinuation
- 2001-07-02 MX MXPA01006803A patent/MXPA01006803A/es active IP Right Grant
- 2001-07-02 JP JP2001201173A patent/JP2002087952A/ja active Pending
- 2001-07-03 CO CO01052475A patent/CO5271674A1/es not_active Application Discontinuation
- 2001-09-29 SA SA01220402A patent/SA01220402B1/ar unknown
-
2007
- 2007-04-05 US US11/696,821 patent/US20070196489A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01006803A (es) | 2003-08-20 |
| ZA200105407B (en) | 2003-01-02 |
| CO5271674A1 (es) | 2003-04-30 |
| US20020031552A1 (en) | 2002-03-14 |
| ES2311500T3 (es) | 2009-02-16 |
| EP1166777B1 (en) | 2008-08-13 |
| JP2002087952A (ja) | 2002-03-27 |
| US20070196489A1 (en) | 2007-08-23 |
| BR0103033A (pt) | 2002-03-05 |
| CN1356102A (zh) | 2002-07-03 |
| ATE404180T1 (de) | 2008-08-15 |
| SA01220402B1 (ar) | 2007-02-07 |
| AU784613B2 (en) | 2006-05-11 |
| CA2351814C (en) | 2009-11-17 |
| US7223421B2 (en) | 2007-05-29 |
| NZ512683A (en) | 2003-02-28 |
| AU5415801A (en) | 2002-01-03 |
| DE60135273D1 (de) | 2008-09-25 |
| CA2351814A1 (en) | 2001-12-30 |
| EP1166777A1 (en) | 2002-01-02 |
| KR20020002321A (ko) | 2002-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |