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AR028250A1 - IMIDAZO [1,5-A] -PIRIDO [3,2-E] -PIRAZINONAS, THE USE OF SUCH COMPOUNDS AND ITS SALTS FOR THE PREPARATION OF MEDICINES AND THE MEDICINES SO PREPARED - Google Patents

IMIDAZO [1,5-A] -PIRIDO [3,2-E] -PIRAZINONAS, THE USE OF SUCH COMPOUNDS AND ITS SALTS FOR THE PREPARATION OF MEDICINES AND THE MEDICINES SO PREPARED

Info

Publication number
AR028250A1
AR028250A1 ARP010101174A ARP010101174A AR028250A1 AR 028250 A1 AR028250 A1 AR 028250A1 AR P010101174 A ARP010101174 A AR P010101174A AR P010101174 A ARP010101174 A AR P010101174A AR 028250 A1 AR028250 A1 AR 028250A1
Authority
AR
Argentina
Prior art keywords
medicines
pirazinonas
pirido
imidazo
salts
Prior art date
Application number
ARP010101174A
Other languages
Spanish (es)
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of AR028250A1 publication Critical patent/AR028250A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ARP010101174A 2000-03-14 2001-03-13 IMIDAZO [1,5-A] -PIRIDO [3,2-E] -PIRAZINONAS, THE USE OF SUCH COMPOUNDS AND ITS SALTS FOR THE PREPARATION OF MEDICINES AND THE MEDICINES SO PREPARED AR028250A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10012373A DE10012373A1 (en) 2000-03-14 2000-03-14 Treating erectile dysfunction using new or known imidazo(1,5-a)pyrido(3,2-e)pyrazinone derivatives, as cGMP-selective phosphodiesterase V inhibitors free of cardiovascular side-effects

Publications (1)

Publication Number Publication Date
AR028250A1 true AR028250A1 (en) 2003-04-30

Family

ID=7634668

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010101174A AR028250A1 (en) 2000-03-14 2001-03-13 IMIDAZO [1,5-A] -PIRIDO [3,2-E] -PIRAZINONAS, THE USE OF SUCH COMPOUNDS AND ITS SALTS FOR THE PREPARATION OF MEDICINES AND THE MEDICINES SO PREPARED

Country Status (14)

Country Link
EP (1) EP1267877A1 (en)
JP (1) JP2003528056A (en)
AR (1) AR028250A1 (en)
AU (1) AU2001244192A1 (en)
BG (1) BG107077A (en)
BR (1) BR0109163A (en)
CZ (1) CZ20023078A3 (en)
DE (1) DE10012373A1 (en)
HU (1) HUP0300551A2 (en)
IL (1) IL151646A0 (en)
NO (1) NO20024364L (en)
RU (1) RU2002127413A (en)
SK (1) SK13232002A3 (en)
WO (1) WO2001068097A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
AR059898A1 (en) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv DERIVATIVES OF 3-CIANO-PIRIDONA 1,4-DISUSTITUTED AND ITS USE AS ALLOSTERIC MODULATORS OF MGLUR2 RECEIVERS
RU2308271C1 (en) * 2006-07-28 2007-10-20 Михаил Иосифович Коган Method for preventing the development of erectile dysfunction in patients after urethral trauma
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
RU2345778C1 (en) * 2007-04-26 2009-02-10 ФГУ "Московский научно-исследовательский институт психиатрии Федерального агентства по здравоохранению и социальному развитию" Method for erectile dysfunction treatment in men
DE602008004794D1 (en) 2007-09-14 2011-03-10 Addex Pharmaceuticals Sa 1 ', 3'-DISUBSTITUTED 4-PHENYL-3,4,5,6-TETRAHYDRO-2H, 1'H-Ä1,4'-UPBIPYRIDINYL-2'-ONE
KR20100065191A (en) 2007-09-14 2010-06-15 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
RU2010126622A (en) 2007-11-30 2012-01-10 УАЙТ ЭлЭлСи (US) IMIDAZO [1, 5-A] PYRASINES CONDENSED WITH Aryl and Heteroaryl as Pyrophosphodiesterase Inhibitors 10
EP2344470B1 (en) 2008-09-02 2013-11-06 Janssen Pharmaceuticals, Inc. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
CN102232074B (en) 2008-11-28 2014-12-03 奥梅-杨森制药有限公司 Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
WO2010130422A1 (en) 2009-05-12 2010-11-18 Ortho-Mcneil-Janssen Pharmaceuticals, Inc 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
AR076861A1 (en) 2009-05-12 2011-07-13 Addex Pharma Sa DERIVATIVES OF 1,2,4-TRIAZOLO (4,3-A) PIRIDINE AND ITS USE AS POSITIVE ALOSTERIC MODULATORS OF MGLUR2 RECEIVERS
CA2814998C (en) 2010-11-08 2019-10-29 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
ES2552455T3 (en) 2010-11-08 2015-11-30 Janssen Pharmaceuticals, Inc. 1,2,4-Triazolo [4,3-a] pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
US8993591B2 (en) 2010-11-08 2015-03-31 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
WO2013192225A1 (en) * 2012-06-18 2013-12-27 Dart Neuroscience (Cayman) Ltd Substituted thiophene- and furan-fused azolopyrimidine-5-(6h)-one compounds
JO3368B1 (en) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv 6, 7- dihydropyrazolu [5,1-a] pyrazine-4 (5 hands) -on compounds and their use as negative excretory regulators of Miglore 2 receptors.
JO3367B1 (en) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv 1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
SMT201900545T1 (en) 2014-01-21 2019-11-13 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
PH12019500127B1 (en) 2014-01-21 2022-05-04 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
JP6420400B2 (en) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・（ケイマン）・リミテッド Substituted pyridine azolopyrimidin-5- (6H) -one compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055465A (en) * 1989-05-31 1991-10-08 Berlex Laboratories, Inc. Imidazoquinoxalinones, their aza analogs and process for their preparation
WO1993020077A1 (en) * 1992-04-03 1993-10-14 Yamanouchi Pharmaceutical Co., Ltd. Fused quinoxalinone derivative and pharmaceutical composition containing the same
DE4228095A1 (en) * 1992-08-24 1994-03-03 Asta Medica Ag New 4,5-dihydro-4-oxopyrrolo [1,2-a] quinoxalines and corresponding aza analogues and processes for their preparation
DE4338948A1 (en) * 1993-11-15 1995-05-18 Carlen Judith Treating erectile dysfunction without causing side-effects
DE19510965A1 (en) * 1995-03-24 1996-09-26 Asta Medica Ag New pyrido / 3,2-e / pyrazinone with anti-asthmatic activity and process for their preparation
DE19728301A1 (en) * 1997-07-03 1999-01-07 Dresden Arzneimittel Use of inhibitors of phosphodiesterase 4 for the treatment of allergic rhinitis

Also Published As

Publication number Publication date
NO20024364L (en) 2002-09-27
IL151646A0 (en) 2003-04-10
HUP0300551A2 (en) 2003-07-28
NO20024364D0 (en) 2002-09-12
AU2001244192A1 (en) 2001-09-24
SK13232002A3 (en) 2003-05-02
BG107077A (en) 2003-05-30
WO2001068097A1 (en) 2001-09-20
EP1267877A1 (en) 2003-01-02
CZ20023078A3 (en) 2003-03-12
DE10012373A1 (en) 2001-09-20
BR0109163A (en) 2002-11-26
JP2003528056A (en) 2003-09-24
RU2002127413A (en) 2004-02-27

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