AR026450A1 - Cemento hidraulico de brushita estabilizado con una sal de magnesio - Google Patents
Cemento hidraulico de brushita estabilizado con una sal de magnesioInfo
- Publication number
- AR026450A1 AR026450A1 ARP000105974A ARP000105974A AR026450A1 AR 026450 A1 AR026450 A1 AR 026450A1 AR P000105974 A ARP000105974 A AR P000105974A AR P000105974 A ARP000105974 A AR P000105974A AR 026450 A1 AR026450 A1 AR 026450A1
- Authority
- AR
- Argentina
- Prior art keywords
- component
- brushita
- stabilized
- magnesium salt
- hydraulic cement
- Prior art date
Links
- 239000011396 hydraulic cement Substances 0.000 title 1
- 159000000003 magnesium salts Chemical class 0.000 title 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 2
- 239000004568 cement Substances 0.000 abstract 2
- 239000012467 final product Substances 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- CKRORYDHXIRZCH-UHFFFAOYSA-N phosphoric acid;dihydrate Chemical compound O.O.OP(O)(O)=O CKRORYDHXIRZCH-UHFFFAOYSA-N 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
- C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
- C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
- C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Ceramic Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Abstract
El cemento de brushita para propositos quirurgicos comprende un primer componente que comprende un fosfato básico de calcio, un segundo componente quecomprende un fosfato acídico, un tercer componente que comprende agua, y un cuarto componente que co mprende una fuente de magnesio utilizada para estabilizarel producto final de la reaccion de fraguado entre los componentes. La solubilidad de la fuente de magnesio es menor que 100 g/l. Los componentes estánelegidos en cantidades tales que (i) el pH de la pasta de cemento durante el fraguado es menor que 6,0; y (ii) el producto final de la reaccion de fraguadocomprende dihidrato de fosfato [CaHPO42H2O].
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CH1999/000595 WO2001041824A1 (en) | 1999-12-09 | 1999-12-09 | Brushite hydraulic cement stabilized with a magnesium salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR026450A1 true AR026450A1 (es) | 2003-02-12 |
Family
ID=4551748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000105974A AR026450A1 (es) | 1999-12-09 | 2000-11-13 | Cemento hidraulico de brushita estabilizado con una sal de magnesio |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6733582B1 (es) |
| EP (1) | EP1235599B1 (es) |
| JP (1) | JP5383961B2 (es) |
| KR (1) | KR20020064926A (es) |
| CN (2) | CN101347635B (es) |
| AR (1) | AR026450A1 (es) |
| AT (1) | ATE245456T1 (es) |
| AU (1) | AU766371B2 (es) |
| BR (1) | BR9917570A (es) |
| CA (1) | CA2391947C (es) |
| DE (1) | DE69909850T2 (es) |
| DK (1) | DK1235599T3 (es) |
| ES (1) | ES2204198T3 (es) |
| MX (1) | MXPA02004591A (es) |
| PT (1) | PT1235599E (es) |
| WO (1) | WO2001041824A1 (es) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2463742C (fr) * | 2001-11-14 | 2010-08-10 | Ecole Polytechnique Federale De Lausanne (Epfl) | Multicomposants pateux ou liquides pour ciments phosphocalciques injectables |
| TW200400062A (en) * | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
| CA2487994C (en) * | 2002-06-19 | 2011-11-01 | Marc Bohner | Hydraulic cement based on calcium phosphate for surgical use |
| GB0222291D0 (en) * | 2002-09-26 | 2002-10-30 | Smith & Nephew | Adhesive bone cement |
| WO2005027988A2 (en) * | 2003-09-05 | 2005-03-31 | Norian Corporation | Bone cement compositions having fiber-reinforcement and/or increased flowability |
| GB2407580B (en) * | 2003-10-28 | 2009-02-25 | Univ Cambridge Tech | Biomaterial |
| US7351280B2 (en) | 2004-02-10 | 2008-04-01 | New York University | Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment |
| US7175858B2 (en) * | 2004-07-26 | 2007-02-13 | Skeletal Kinetics Llc | Calcium phosphate cements and methods for using the same |
| US9078884B2 (en) | 2004-09-21 | 2015-07-14 | Thomas Joseph Lally | Bio-material composition and method for spinal fusion |
| CN101076344B (zh) * | 2004-09-21 | 2011-07-13 | T·J·拉利 | 多用途生物材料组合物 |
| US20080119859A1 (en) * | 2005-01-12 | 2008-05-22 | Lally Thomas J | Multi-Purpose Bio-Material Composition |
| US7416602B2 (en) * | 2005-04-08 | 2008-08-26 | Howmedica Leibinger, Inc. | Calcium phosphate cement |
| US7459018B2 (en) * | 2005-04-08 | 2008-12-02 | Howmedica Leibinger Inc. | Injectable calcium phosphate cement |
| WO2007030616A2 (en) | 2005-09-09 | 2007-03-15 | Wright Medical Technology, Inc. | Composite bone graft substitute cement and articles produced therefrom |
| CN100372575C (zh) * | 2005-09-28 | 2008-03-05 | 浙江大学 | 一种具有非均质涂层的医用材料及其制备方法 |
| ES2301320B1 (es) * | 2005-12-15 | 2009-05-01 | Faleh Tamimi Mariño | Granulado de cemento de brushita fraguado con acido glicolico para regeneracion osea. |
| DE102006042142A1 (de) | 2006-09-06 | 2008-03-27 | Curasan Ag | Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung |
| FR2911508B1 (fr) * | 2007-01-19 | 2012-11-09 | Kasios | Substitut osseux a base de ciment phosphocalcique |
| US9433704B2 (en) * | 2007-03-09 | 2016-09-06 | Novabone Products, Llc | Osteostimulative settable bone graft putty |
| US20080317807A1 (en) * | 2007-06-22 | 2008-12-25 | The University Of Hong Kong | Strontium fortified calcium nano-and microparticle compositions and methods of making and using thereof |
| AU2008355685B2 (en) | 2008-05-02 | 2013-10-31 | Dr.H.C. Robert Mathys Stiftung | Calcium phosphate particles and hydraulic cements based thereon |
| US20100001090A1 (en) * | 2008-07-03 | 2010-01-07 | Arthur Hampton Neergaard | Liquid Particle Emitting Device |
| WO2010004057A1 (es) | 2008-07-08 | 2010-01-14 | Histocell, S.L | MATRICES TRIDIMENSIONALES DE MONETITA POROSA ESTRUCTURADA PARA INGENIERIA TISULAR Y REGENERACION OSEA, Y METODO DE PREPARACIόN DE LAS MISMAS |
| WO2010055483A2 (en) | 2008-11-12 | 2010-05-20 | Engqvist Haakan | Hydraulic cements, methods and products |
| CN102448471B (zh) | 2009-03-30 | 2017-04-12 | 可乐丽则武齿科株式会社 | 牙本质矿化剂和其制造方法 |
| CN105125323B (zh) | 2010-03-10 | 2017-04-12 | 奥斯-Q公司 | 用于修复组织缺损的植入体和方法 |
| US10182973B2 (en) | 2010-11-10 | 2019-01-22 | Stryker European Holdings I, Llc | Polymeric bone foam composition and method |
| US8226766B2 (en) * | 2010-12-22 | 2012-07-24 | United States Gypsum Company | Set accelerator for gypsum hydration |
| WO2012089276A1 (en) | 2010-12-31 | 2012-07-05 | Ahmet Cuneyt Tas | Preparation method of brushite and octacalcium phosphate granules |
| RU2477120C2 (ru) * | 2011-04-04 | 2013-03-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет"(НИУ "БелГУ") | Способ получения цемента брушитного типа для замещения костных дефектов |
| CN102274543A (zh) * | 2011-08-01 | 2011-12-14 | 天津美基生物医药科技有限公司 | 镁基骨填充粘合剂及其制备方法与应用 |
| US9463046B2 (en) | 2011-08-22 | 2016-10-11 | Ossdsign Ab | Implants and methods for using such implants to fill holes in bone tissue |
| US8591645B2 (en) | 2011-09-09 | 2013-11-26 | Ossdsign Ab | Hydraulic cements with optimized grain size distribution, methods, articles and kits |
| US20130066327A1 (en) | 2011-09-09 | 2013-03-14 | Håkan Engqvist | Hydraulic cement compositions with low ph methods, articles and kits |
| CA2863381C (en) * | 2012-01-31 | 2021-11-16 | The University Of Toledo | Injectable, biodegradable bone cements and methods of making and using same |
| RU2502525C2 (ru) * | 2012-03-13 | 2013-12-27 | Федеральное государственное бюджетное учреждение науки Институт металлургии и материаловедения им. А.А. Байкова Российской академии наук (ИМЕТ РАН) | Брушитовый гидравлический цемент (варианты) |
| RU2485978C1 (ru) * | 2012-06-07 | 2013-06-27 | Федеральное государственное бюджетное учреждение науки Институт металлургии и материаловедения им. А.А. Байкова Российской академии наук (ИМЕТ РАН) | Пористый кальций-фосфатный цемент |
| EP2931325B1 (en) | 2012-12-14 | 2020-02-19 | OssDsign AB | Cement-forming compositions, monetite cements, implants and methods for correcting bone defects |
| HK1217632A1 (zh) | 2013-02-12 | 2017-01-20 | Ossdsign Ab | 镶嵌型植人物、试剂盒和用於矫正骨缺损的方法 |
| AU2013387611B2 (en) * | 2013-04-22 | 2017-06-01 | Mathys Ag Bettlach | Calcium phosphate cement composition |
| TWI651103B (zh) | 2013-12-13 | 2019-02-21 | 萊特醫技股份有限公司 | 多相骨移植替代材料 |
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| US10881519B2 (en) | 2014-08-14 | 2021-01-05 | Ossdsign Ab | Bone implants for correcting bone defects |
| FR3030498B1 (fr) * | 2014-12-23 | 2019-06-07 | Saint-Gobain Weber | Liant acido-basique comprenant des ciments a base de phosphate |
| WO2016109555A1 (en) | 2014-12-29 | 2016-07-07 | Bioventus, Llc | Systems and methods for improved delivery of osteoinductive molecules in bone repair |
| US20180264167A1 (en) * | 2015-09-23 | 2018-09-20 | Ossdsign Ab | Cement-forming compositions, apatite cements, implants and methods for correcting bone defects |
| CN105833338A (zh) * | 2016-04-25 | 2016-08-10 | 天津市赛宁生物工程技术有限公司 | 可用于医用组织粘合剂的有机镁盐复合物 |
| KR101978386B1 (ko) * | 2016-10-06 | 2019-05-15 | 순천향대학교 산학협력단 | 주입형 다공성 브루샤이트 골 충진재용 조성물 키트 및 골 충진재의 제조방법 |
| ES2901421T3 (es) * | 2017-04-11 | 2022-03-22 | Straumann Holding Ag | Implante dental |
| CN107827381B (zh) * | 2017-11-27 | 2020-10-09 | 固岩科技发展有限公司 | 一种磷酸镁胶凝剂及胶凝材料 |
| CN108950443B (zh) * | 2018-07-04 | 2020-01-10 | 郑州大学第一附属医院 | 一种具有抗菌和骨诱导活性功能的医用钛合金棒材 |
| BR112021007281A2 (pt) | 2018-10-16 | 2021-07-20 | Ossdsign Ab | implantes para preencher orifícios perfurados no osso e métodos para preencher orifícios perfurados no osso |
| US20220169572A1 (en) * | 2019-03-29 | 2022-06-02 | Goodwin Plc | Investment powder |
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| US12343444B2 (en) | 2021-08-16 | 2025-07-01 | Bone Solutions, Inc. | Structural implant to prevent bone defects |
| KR102660274B1 (ko) * | 2022-08-30 | 2024-04-24 | 이노시스 주식회사 | 마그네슘 이온을 함유하는 골 이식재 및 이를 위한 경화액 |
| CN115382012A (zh) * | 2022-09-21 | 2022-11-25 | 苏州大学 | 一种透钙磷石骨水泥及其制备方法和应用 |
| KR102672911B1 (ko) * | 2022-11-08 | 2024-06-10 | 영남대학교 산학협력단 | Plla/bcp 복합소재의 제조방법, 이를 이용한 골조직 재생용 생체활성 지지체의 제조방법 및 골조직 재생용 생체활성 지지체의 제조방법으로 제조된 골조직 재생용 생체활성 지지체 |
| CN116407686B (zh) * | 2022-12-29 | 2025-02-11 | 南京航空航天大学 | 一种高生物活性的透钙磷石/β-磷酸三钙骨组织工程支架的制备方法 |
| CN116812890A (zh) * | 2023-07-07 | 2023-09-29 | 国纳之星(上海)纳米科技发展有限公司 | 一种牙膏摩擦剂二水磷酸氢钙的生产工艺 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4707361A (en) * | 1985-08-02 | 1987-11-17 | Stauffer Chemical Company | Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting |
| US5962028A (en) * | 1988-04-20 | 1999-10-05 | Norian Corporation | Carbonated hydroxyapatite compositions and uses |
| JPH02102657A (ja) * | 1988-10-12 | 1990-04-16 | Mitsubishi Mining & Cement Co Ltd | 骨欠損部、骨空隙部及び歯牙根管部充てん材 |
| JPH03178909A (ja) * | 1989-12-06 | 1991-08-02 | Dainippon Toryo Co Ltd | 根管充填材 |
| JP2621622B2 (ja) | 1990-09-27 | 1997-06-18 | 三菱マテリアル株式会社 | 水硬性リン酸カルシウムセメント |
| US5605713A (en) * | 1991-11-22 | 1997-02-25 | Boltong; Maria G. | Process for the preparation of calcium phosphate cements and its application as bio-materials |
| ES2040626B1 (es) * | 1991-11-22 | 1994-05-16 | Boltong Maria G | Procedimiento para la obtencion de cementos de fosfatos de calcio y su empleo como biomteriales. |
| JPH078548A (ja) * | 1993-06-24 | 1995-01-13 | Mitsui Toatsu Chem Inc | 硬化性生体用粉材 |
| US5496399A (en) * | 1994-08-23 | 1996-03-05 | Norian Corporation | Storage stable calcium phosphate cements |
| DE69803398T2 (de) * | 1997-10-07 | 2002-09-26 | Dr. H.C. Robert Mathys Stiftung, Bettlach | Hydraulischer chirurgischer zement |
-
1999
- 1999-12-09 EP EP99974248A patent/EP1235599B1/en not_active Expired - Lifetime
- 1999-12-09 CA CA002391947A patent/CA2391947C/en not_active Expired - Fee Related
- 1999-12-09 CN CN2008101460929A patent/CN101347635B/zh not_active Expired - Fee Related
- 1999-12-09 DE DE69909850T patent/DE69909850T2/de not_active Expired - Lifetime
- 1999-12-09 BR BR9917570-3A patent/BR9917570A/pt not_active IP Right Cessation
- 1999-12-09 JP JP2001543168A patent/JP5383961B2/ja not_active Expired - Fee Related
- 1999-12-09 ES ES99974248T patent/ES2204198T3/es not_active Expired - Lifetime
- 1999-12-09 AT AT99974248T patent/ATE245456T1/de active
- 1999-12-09 US US10/149,035 patent/US6733582B1/en not_active Expired - Lifetime
- 1999-12-09 KR KR1020027007307A patent/KR20020064926A/ko not_active Abandoned
- 1999-12-09 PT PT99974248T patent/PT1235599E/pt unknown
- 1999-12-09 MX MXPA02004591A patent/MXPA02004591A/es not_active IP Right Cessation
- 1999-12-09 AU AU13721/00A patent/AU766371B2/en not_active Ceased
- 1999-12-09 CN CN99817016A patent/CN1378464A/zh active Pending
- 1999-12-09 WO PCT/CH1999/000595 patent/WO2001041824A1/en not_active Ceased
- 1999-12-09 DK DK99974248T patent/DK1235599T3/da active
-
2000
- 2000-11-13 AR ARP000105974A patent/AR026450A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02004591A (es) | 2004-09-10 |
| US6733582B1 (en) | 2004-05-11 |
| ATE245456T1 (de) | 2003-08-15 |
| JP5383961B2 (ja) | 2014-01-08 |
| ES2204198T3 (es) | 2004-04-16 |
| DK1235599T3 (da) | 2003-10-20 |
| DE69909850T2 (de) | 2004-05-27 |
| EP1235599A1 (en) | 2002-09-04 |
| JP2003516190A (ja) | 2003-05-13 |
| AU1372100A (en) | 2001-06-18 |
| CN1378464A (zh) | 2002-11-06 |
| CN101347635A (zh) | 2009-01-21 |
| WO2001041824A1 (en) | 2001-06-14 |
| BR9917570A (pt) | 2002-08-06 |
| DE69909850D1 (de) | 2003-08-28 |
| CA2391947A1 (en) | 2001-06-14 |
| CA2391947C (en) | 2008-07-15 |
| AU766371B2 (en) | 2003-10-16 |
| CN101347635B (zh) | 2013-10-16 |
| KR20020064926A (ko) | 2002-08-10 |
| EP1235599B1 (en) | 2003-07-23 |
| PT1235599E (pt) | 2003-12-31 |
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