AR026040A1 - Sistema terapeutico transdermal que contiene clorhidrato de tulobuterol para la administracion del broncodilatador tulobuterol a traves de la piel - Google Patents
Sistema terapeutico transdermal que contiene clorhidrato de tulobuterol para la administracion del broncodilatador tulobuterol a traves de la pielInfo
- Publication number
- AR026040A1 AR026040A1 ARP000105398A ARP000105398A AR026040A1 AR 026040 A1 AR026040 A1 AR 026040A1 AR P000105398 A ARP000105398 A AR P000105398A AR P000105398 A ARP000105398 A AR P000105398A AR 026040 A1 AR026040 A1 AR 026040A1
- Authority
- AR
- Argentina
- Prior art keywords
- tulobuterol
- therapeutic system
- transdermal therapeutic
- chlorhydrate
- bronchodilator
- Prior art date
Links
- YREYLAVBNPACJM-UHFFFAOYSA-N 2-(tert-butylamino)-1-(2-chlorophenyl)ethanol Chemical compound CC(C)(C)NCC(O)C1=CC=CC=C1Cl YREYLAVBNPACJM-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000859 tulobuterol Drugs 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 229940124630 bronchodilator Drugs 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000004821 Contact adhesive Substances 0.000 abstract 1
- RSLNRVYIRDVHLY-UHFFFAOYSA-N Tulobuterol hydrochloride Chemical class [Cl-].CC(C)(C)[NH2+]CC(O)C1=CC=CC=C1Cl RSLNRVYIRDVHLY-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229920000058 polyacrylate Polymers 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Un sistema terapéutico transdermal que comprende una capa superior básicamente impermeable al vapor de agua, al menos una capa matriz que contiene comoprincipio activo tulobuterol, así como una capa protectora amovible, se caracteriza por estarforma da la matriz a base de adhesivos de contacto de poliacrilatoy contener tulobuterol en forma de su sal de clorhidrato de tulobuterol como principio activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19950066A DE19950066A1 (de) | 1999-10-16 | 1999-10-16 | Transdermales therapeutisches System mit einem Gehalt an Tulobuterol-hydrochlorid zur Verabreichung des Bronchodilatators Tulobuterol über die Haut |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR026040A1 true AR026040A1 (es) | 2002-12-26 |
Family
ID=7925993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000105398A AR026040A1 (es) | 1999-10-16 | 2000-10-13 | Sistema terapeutico transdermal que contiene clorhidrato de tulobuterol para la administracion del broncodilatador tulobuterol a traves de la piel |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7056528B1 (es) |
| EP (1) | EP1220662B1 (es) |
| JP (2) | JP4874486B2 (es) |
| KR (1) | KR101014074B1 (es) |
| AR (1) | AR026040A1 (es) |
| AT (1) | ATE299019T1 (es) |
| AU (1) | AU7662400A (es) |
| CA (1) | CA2387143C (es) |
| DE (2) | DE19950066A1 (es) |
| ES (1) | ES2245648T3 (es) |
| PT (1) | PT1220662E (es) |
| WO (1) | WO2001028531A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100469995B1 (ko) * | 2002-05-20 | 2005-02-05 | 안국약품 주식회사 | 천식치료제를 함유한 매트릭스형 패취 |
| EP1557164A4 (en) * | 2003-06-20 | 2006-03-15 | Teikoku Seiyaku Kk | ADHESIVE PATTERN WITH TULOBUTEROL |
| DE10340152B4 (de) | 2003-09-01 | 2006-05-04 | BÖCO Böddecker & Co. GmbH & Co. KG | Schloß mit einer Drehfalle und einer Sperrklinke |
| RU2356580C2 (ru) * | 2003-10-28 | 2009-05-27 | Новен Фармасьютикалз, Инк | Композиции и способы, обеспечивающие контролируемую потерю лекарственных средств и доставку в системах трансдермальной доставки лекарственных средств |
| CN1297257C (zh) * | 2004-01-02 | 2007-01-31 | 上海现代药物制剂工程研究中心有限公司 | 含有妥洛特罗的压敏胶,透皮贴剂及制备方法和应用 |
| WO2006051819A1 (ja) | 2004-11-10 | 2006-05-18 | Hisamitsu Pharmaceutical Co., Inc. | 外用製剤及び貼付剤 |
| US20070298089A1 (en) * | 2004-11-10 | 2007-12-27 | Masakazu Saeki | Drug for External Use and Adhesive Patch |
| US8080560B2 (en) * | 2004-12-17 | 2011-12-20 | 3M Innovative Properties Company | Immune response modifier formulations containing oleic acid and methods |
| DE102004062614B4 (de) * | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
| CA2976789C (en) * | 2009-06-05 | 2019-12-31 | Megtec Systems, Inc. | Method of drying a web of printed material |
| JP5766475B2 (ja) * | 2010-03-30 | 2015-08-19 | 日東電工株式会社 | 貼付製剤およびその製造方法 |
| EP2688561B1 (en) * | 2011-03-24 | 2018-08-22 | Teikoku Pharma USA, Inc. | Transdermal compositions comprising an active agent layer and an active agent conversion layer |
| US9120956B2 (en) | 2011-07-21 | 2015-09-01 | Teikoku Seiyaku Co., Ltd. | Water-based plaster |
| JP6325985B2 (ja) | 2012-01-11 | 2018-05-16 | アデレイド リサーチ アンド イノベーション ピーティーワイ リミテッド | 固体媒体上に貯蔵された生物学的サンプル中の脂肪酸の安定化および分析 |
| CN102552221B (zh) * | 2012-01-11 | 2013-09-04 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种妥洛特罗贴剂及其制备方法 |
| KR101856515B1 (ko) | 2012-11-02 | 2018-05-10 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 프로피닐아미노인단 경피 조성물 |
| EA034204B1 (ru) | 2014-10-17 | 2020-01-16 | Фидия Фармачеутичи С.П.А. | Дермальная терапевтическая система с высокой адгезивной способностью |
| TWI741168B (zh) * | 2017-04-28 | 2021-10-01 | 日商日東電工股份有限公司 | 經皮吸收製劑 |
| CN109541065B (zh) * | 2018-12-04 | 2019-10-01 | 山东大学 | 一种妥洛特罗贴剂的分析方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU197847B (en) * | 1984-03-01 | 1989-06-28 | Sandoz Ag | Process for producing therapeutical preparations suitable for transdermatic treating |
| JPH0725669B2 (ja) | 1988-12-23 | 1995-03-22 | 日東電工株式会社 | 経皮投与用医薬製剤 |
| DE4002281A1 (de) * | 1990-01-26 | 1991-08-01 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit dem wirkstoff tulobuterol |
| IT1251469B (it) | 1991-07-15 | 1995-05-15 | Zambon Spa | Sistema terapeutico transdermale per la somministrazione di farmaci ad attivita' broncodilatante. |
| EP0593807A1 (en) * | 1992-10-22 | 1994-04-27 | LTS Lohmann Therapie-Systeme GmbH & Co. KG | Patch for transdermal administration of volatile pharmaceutically active ingredients of chemically basic nature and a process for preparation |
| CN1076972C (zh) * | 1992-07-23 | 2002-01-02 | 久光制药株式会社 | 经皮肤给药的基剂组合物及其药剂组合物 |
| JP2753800B2 (ja) * | 1994-04-14 | 1998-05-20 | 日東電工株式会社 | 経皮吸収型製剤 |
| JP3466305B2 (ja) * | 1994-12-12 | 2003-11-10 | 久光製薬株式会社 | 溶解剤および該溶解剤を含有する外用製剤 |
| CA2264524A1 (en) * | 1996-10-04 | 1998-04-09 | Norihiro Shinkai | Patch |
| DE19653605C2 (de) * | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| IT1294748B1 (it) * | 1997-09-17 | 1999-04-12 | Permatec Tech Ag | Formulazione per un dispositivo transdermico |
| JP3930984B2 (ja) * | 1997-12-12 | 2007-06-13 | 日東電工株式会社 | 経皮吸収型製剤 |
| US6375963B1 (en) * | 1999-06-16 | 2002-04-23 | Michael A. Repka | Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof |
-
1999
- 1999-10-16 DE DE19950066A patent/DE19950066A1/de not_active Ceased
-
2000
- 2000-10-06 EP EP00966123A patent/EP1220662B1/de not_active Expired - Lifetime
- 2000-10-06 ES ES00966123T patent/ES2245648T3/es not_active Expired - Lifetime
- 2000-10-06 AT AT00966123T patent/ATE299019T1/de active
- 2000-10-06 WO PCT/EP2000/009788 patent/WO2001028531A1/de not_active Ceased
- 2000-10-06 CA CA002387143A patent/CA2387143C/en not_active Expired - Fee Related
- 2000-10-06 US US10/110,014 patent/US7056528B1/en not_active Expired - Fee Related
- 2000-10-06 AU AU76624/00A patent/AU7662400A/en not_active Abandoned
- 2000-10-06 JP JP2001531361A patent/JP4874486B2/ja not_active Expired - Fee Related
- 2000-10-06 DE DE50010679T patent/DE50010679D1/de not_active Expired - Lifetime
- 2000-10-06 PT PT00966123T patent/PT1220662E/pt unknown
- 2000-10-13 AR ARP000105398A patent/AR026040A1/es unknown
-
2002
- 2002-04-16 KR KR1020027004866A patent/KR101014074B1/ko not_active Expired - Fee Related
-
2011
- 2011-08-05 JP JP2011171931A patent/JP2011252003A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003528037A (ja) | 2003-09-24 |
| EP1220662A1 (de) | 2002-07-10 |
| CA2387143C (en) | 2009-06-02 |
| DE19950066A1 (de) | 2001-04-26 |
| EP1220662B1 (de) | 2005-07-06 |
| ES2245648T3 (es) | 2006-01-16 |
| KR101014074B1 (ko) | 2011-02-14 |
| KR20020047240A (ko) | 2002-06-21 |
| JP4874486B2 (ja) | 2012-02-15 |
| WO2001028531A1 (de) | 2001-04-26 |
| ATE299019T1 (de) | 2005-07-15 |
| JP2011252003A (ja) | 2011-12-15 |
| PT1220662E (pt) | 2005-10-31 |
| US7056528B1 (en) | 2006-06-06 |
| AU7662400A (en) | 2001-04-30 |
| DE50010679D1 (de) | 2005-08-11 |
| CA2387143A1 (en) | 2001-04-26 |
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