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AR013844A1 - Compuestos derivados de 3-oxo-pirido[1,2-a] bencimidazol-4-carboxamida sustituidos en posicion 5 con alquilo que contiene heteroatomo,- y composiciones farmaceuticas que los comprenden. - Google Patents

Compuestos derivados de 3-oxo-pirido[1,2-a] bencimidazol-4-carboxamida sustituidos en posicion 5 con alquilo que contiene heteroatomo,- y composiciones farmaceuticas que los comprenden.

Info

Publication number
AR013844A1
AR013844A1 ARP970104602A ARP970104602A AR013844A1 AR 013844 A1 AR013844 A1 AR 013844A1 AR P970104602 A ARP970104602 A AR P970104602A AR P970104602 A ARP970104602 A AR P970104602A AR 013844 A1 AR013844 A1 AR 013844A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical compositions
heteroatomo
bencimidazol
pirido
rent
Prior art date
Application number
ARP970104602A
Other languages
English (en)
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of AR013844A1 publication Critical patent/AR013844A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se descrubre un compuesto de la formula general I como util en eln tratamiento de desordenes del sistema nervioso central. Además se descubrencomposiciones farmacéuticas y métodos de tratamiento.
ARP970104602A 1996-10-07 1997-10-06 Compuestos derivados de 3-oxo-pirido[1,2-a] bencimidazol-4-carboxamida sustituidos en posicion 5 con alquilo que contiene heteroatomo,- y composiciones farmaceuticas que los comprenden. AR013844A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2751196P 1996-10-07 1996-10-07

Publications (1)

Publication Number Publication Date
AR013844A1 true AR013844A1 (es) 2001-01-31

Family

ID=21838133

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970104602A AR013844A1 (es) 1996-10-07 1997-10-06 Compuestos derivados de 3-oxo-pirido[1,2-a] bencimidazol-4-carboxamida sustituidos en posicion 5 con alquilo que contiene heteroatomo,- y composiciones farmaceuticas que los comprenden.

Country Status (13)

Country Link
US (1) US5817668A (es)
EP (1) EP0935598B1 (es)
JP (1) JP2001501949A (es)
AR (1) AR013844A1 (es)
AT (1) ATE256126T1 (es)
AU (1) AU719333B2 (es)
CA (1) CA2267943A1 (es)
DE (1) DE69726749T2 (es)
DK (1) DK0935598T3 (es)
ES (1) ES2212081T3 (es)
NZ (1) NZ335060A (es)
PT (1) PT935598E (es)
WO (1) WO1998015553A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922731A (en) * 1997-06-30 1999-07-13 Ortho Pharmaceutical Corporation 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders
DE69824195T2 (de) * 1997-10-07 2005-06-23 Ortho-Mcneil Pharmaceutical, Inc. Dipyridoimidazolderivate zur behandlung von störungen des zentralen nervensystems
US6200984B1 (en) * 1997-10-07 2001-03-13 Ortho-Mcneil Pharmaceutical, Inc. Naphtho-imidazo pyridine derivatives useful in treating central nervous system disorders
JP2002523399A (ja) * 1998-08-25 2002-07-30 ニューロゲン コーポレイション オキソ−ピリドイミダゾール−カルボキサミド：ｇａｂａ脳レセプタリガンド
US6177569B1 (en) 1998-08-25 2001-01-23 Neurogen Corporation Oxo-pyridoimidazole-carboxamides: GABA brain receptor ligands
MXPA02001308A (es) 1999-08-02 2004-07-16 Johnson & Johnson Derivados de pirido (1, 2-a)bencimidazol sustituidos en el anillo c-6 utiles en el tratamiento de trastornos del sistema nervioso central.
GB0008696D0 (en) 2000-04-07 2000-05-31 Merck Sharp & Dohme Therapeutic agents
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
JP4903385B2 (ja) * 2002-12-06 2012-03-28 パーデュー・リサーチ・ファウンデーション 損傷した哺乳類神経組織を治療するためのピリジン類
US7221138B2 (en) 2005-09-27 2007-05-22 Saifun Semiconductors Ltd Method and apparatus for measuring charge pump output current

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE197455T1 (de) * 1992-08-19 2000-11-11 Mcneilab Inc 3-oxo-pyrido (1,2-a) benzimidazol-4-carboxyl und 4-oxo-azepino (1,2-a) benzimidazol-5-carboxyl derivate geeignet für die behandlung von zentralnervensystemerkrankungen
US5521200A (en) * 1993-12-30 1996-05-28 Ho; Winston 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders

Also Published As

Publication number Publication date
ATE256126T1 (de) 2003-12-15
AU719333B2 (en) 2000-05-04
AU4747397A (en) 1998-05-05
JP2001501949A (ja) 2001-02-13
EP0935598A1 (en) 1999-08-18
PT935598E (pt) 2004-03-31
CA2267943A1 (en) 1998-04-16
DK0935598T3 (da) 2004-03-29
EP0935598B1 (en) 2003-12-10
ES2212081T3 (es) 2004-07-16
DE69726749T2 (de) 2005-07-21
WO1998015553A1 (en) 1998-04-16
NZ335060A (en) 2000-05-26
DE69726749D1 (de) 2004-01-22
US5817668A (en) 1998-10-06

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