AR016806A1 - Procedimiento para la estabilizacion de acido ascorbico levogiro (laa), composicion de laa estabilizado en un medio que contiene agua, emulsion que incluyea dicho laa estabilizado, producto vitaminico que comprende a dicha composicion, procedimiento para preparar dicha composicion y metodo para el t - Google Patents
Procedimiento para la estabilizacion de acido ascorbico levogiro (laa), composicion de laa estabilizado en un medio que contiene agua, emulsion que incluyea dicho laa estabilizado, producto vitaminico que comprende a dicha composicion, procedimiento para preparar dicha composicion y metodo para el tInfo
- Publication number
- AR016806A1 AR016806A1 ARP980103904A ARP980103904A AR016806A1 AR 016806 A1 AR016806 A1 AR 016806A1 AR P980103904 A ARP980103904 A AR P980103904A AR P980103904 A ARP980103904 A AR P980103904A AR 016806 A1 AR016806 A1 AR 016806A1
- Authority
- AR
- Argentina
- Prior art keywords
- laa
- composition
- stabilized
- procedure
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 5
- 229960005070 ascorbic acid Drugs 0.000 title abstract 3
- 235000010323 ascorbic acid Nutrition 0.000 title abstract 3
- 239000011668 ascorbic acid Substances 0.000 title abstract 3
- 239000000839 emulsion Substances 0.000 title abstract 2
- 230000006641 stabilisation Effects 0.000 title abstract 2
- 238000011105 stabilization Methods 0.000 title abstract 2
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 239000000178 monomer Substances 0.000 abstract 2
- 239000011782 vitamin Substances 0.000 abstract 2
- 229940088594 vitamin Drugs 0.000 abstract 2
- 229930003231 vitamin Natural products 0.000 abstract 2
- 235000013343 vitamin Nutrition 0.000 abstract 2
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8129—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un procedimiento para la estabilizacion de LAA en un medio acuoso que comprende la etapa de poner en contacto el LAA con por lo menos un compuesto que escapaz de formar puentes de hidrogeno con el LAA. Dicho compuesto capaz de formar puentes de hidrogeno con el LAA es un polímero que comprende una pluralidad deunidades monoméricas iguales, de peso molecular inferior a 100g/mol, y con un grupo heteroatomico en una cantidad superior a aproximadamente el 70% de larelacion entre la masa molecular dedicho compuesto y el peso molecular de su unidad monomérica. Además, se dan a conocer: una composicion acuosa estable deLAA que comprende, además del referido ácido ascorbico, por lo menos un compuesto que está ligado al LAA por puentes de hidrogeno, y un procedimiento para lapreparacion de la misma; una emulsion que incluye, en una fase acuosa, por lo menos un compuesto ligado al ácido ascorbico levogiro (LAA) a través de puentesde hidrogeno; un producto vitamínico en el que la composicion estable de LAA está contenida en envolturas orgánicas que permiten una liberacion gradual yprolongada de dicho LAA en el organismo. Dicho producto vitamínico puede comprender además por lo menos un compuesto capaz de estimular el metabolismo de losfibroblastos; y un método para el tratamiento cosmético, terapéutico o nutricional que comprende la administracion de dicha composicion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9704418A BR9704418A (pt) | 1997-08-08 | 1997-08-08 | Processo para estabilização de ácido ascórbico levógiro (laa) composição aquosa estável de laa processo para preparação de uma solução tópica estável de laa e método para tratamento cosmético farmacêutico ou nutricional |
| BR9704728A BR9704728B1 (pt) | 1997-09-16 | 1997-09-16 | processo para estabilização de ácido ascórbico levógiro (laa), composição aquosa estável de laa, processo para preparação de uma solução tópica de laa e produto vitamìnico. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR016806A1 true AR016806A1 (es) | 2001-08-01 |
Family
ID=38835018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980103904A AR016806A1 (es) | 1997-08-08 | 1998-08-06 | Procedimiento para la estabilizacion de acido ascorbico levogiro (laa), composicion de laa estabilizado en un medio que contiene agua, emulsion que incluyea dicho laa estabilizado, producto vitaminico que comprende a dicha composicion, procedimiento para preparar dicha composicion y metodo para el t |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6037481A (es) |
| EP (1) | EP0949919B1 (es) |
| JP (1) | JP4011634B2 (es) |
| AR (1) | AR016806A1 (es) |
| CA (1) | CA2268030A1 (es) |
| CO (1) | CO4960667A1 (es) |
| DE (1) | DE69829838T2 (es) |
| PE (1) | PE108599A1 (es) |
| WO (1) | WO1999007362A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6365137B1 (en) | 1999-04-06 | 2002-04-02 | Collaborative Laboratories, Inc. | Skin whitening agents |
| BRPI0003166B1 (pt) * | 1999-07-16 | 2015-08-25 | Natura Cosmeticos Sa | Processo para estabilização de compostos antioxidantes, e composições aquosas |
| US6261566B1 (en) * | 1999-10-22 | 2001-07-17 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing mulberry extract and retinoids |
| US6497889B2 (en) * | 2000-06-20 | 2002-12-24 | Kyowa Hakko Kogyo Co., Ltd. | Cosmetics |
| EP1359885A4 (en) * | 2001-01-25 | 2005-03-16 | Gen Hospital Corp | NOS-HEMMER FOR THE TREATMENT OF WRINKLES |
| DK1842557T3 (da) | 2004-12-22 | 2013-12-02 | Nitto Denko Corp | Lægemiddelbærer og lægemiddelbærerkit til inhibition af fibrose |
| US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| US20070077220A1 (en) * | 2005-09-30 | 2007-04-05 | Ramirez Jose E | Stable ascorbic acid compositions |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| US20070269534A1 (en) * | 2006-02-02 | 2007-11-22 | Ramirez Jose E | Methods of treating skin to enhance therapeutic treatment thereof |
| US20070178058A1 (en) * | 2006-02-02 | 2007-08-02 | Ramirez Jose E | Methods of using stable ascorbic acid compositions |
| TWI407971B (zh) * | 2007-03-30 | 2013-09-11 | Nitto Denko Corp | Cancer cells and tumor-related fibroblasts |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2132662A (en) * | 1937-04-08 | 1938-10-11 | Abbott Lab | Aliphatic amine salts of cevitamic acid |
| US2721161A (en) * | 1951-10-23 | 1955-10-18 | American Home Prod | Ascorbic acid preparation |
| JPS61207316A (ja) * | 1985-03-13 | 1986-09-13 | Shiseido Co Ltd | 皮膚外用剤 |
| CA1325774C (en) * | 1987-01-27 | 1994-01-04 | James M. Wilmott | Cosmetic preparation incorporating stabilized ascorbic acid |
| US4983382A (en) * | 1987-01-27 | 1991-01-08 | Avon Products, Inc. | Cosmetic preparation incorporating stabilized ascorbic acid |
| DK0381543T3 (da) * | 1989-01-31 | 1993-10-04 | Coletica | Anvendelse af opløsninger af atelokollagen og polyholosider, f.eks. glucosaminoglycaner, til fremstilling af mikrokapsler, mikrokapsler fremstillet på denne måde, fremgangsmåder til fremstilling af sådanne mikrokapsler og kosmetiskeeller farmaceutiske sammensætninger eller levnedsmiddelsammensætninger, hvori de er til stede |
| CA2010319C (en) * | 1989-02-20 | 2001-03-13 | Yohzoh Yamamoto | Foamable polymer composition and foamed article |
| US5140043A (en) * | 1989-04-17 | 1992-08-18 | Duke University | Stable ascorbic acid compositions |
| JP2906152B2 (ja) * | 1989-07-18 | 1999-06-14 | 株式会社資生堂 | 過酸化脂質分解剤組成物 |
| US5225220A (en) * | 1990-05-11 | 1993-07-06 | Alpine Lace Brands, Inc. | Process for preparing low fat cheese products |
| JPH07227256A (ja) * | 1993-12-24 | 1995-08-29 | Takeda Chem Ind Ltd | 経口液剤 |
| FR2715844B1 (fr) * | 1994-02-04 | 1996-03-29 | Oreal | Emulsion contenant de l'acide ascorbique stabilisé, procédé de traitement cosmétique la mettant en Óoeuvre, ses utilisations. |
| US5877212A (en) * | 1997-04-16 | 1999-03-02 | Yu; Ruey J. | Molecular complex and control-release of alpha hydroxyacids |
-
1997
- 1997-10-22 US US08/955,524 patent/US6037481A/en not_active Expired - Lifetime
-
1998
- 1998-08-06 AR ARP980103904A patent/AR016806A1/es active IP Right Grant
- 1998-08-06 CO CO98045321A patent/CO4960667A1/es unknown
- 1998-08-07 EP EP98942403A patent/EP0949919B1/en not_active Expired - Lifetime
- 1998-08-07 WO PCT/BR1998/000056 patent/WO1999007362A1/en not_active Ceased
- 1998-08-07 DE DE69829838T patent/DE69829838T2/de not_active Expired - Lifetime
- 1998-08-07 JP JP51144299A patent/JP4011634B2/ja not_active Expired - Fee Related
- 1998-08-07 CA CA002268030A patent/CA2268030A1/en not_active Abandoned
- 1998-08-10 PE PE1998000714A patent/PE108599A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0949919B1 (en) | 2005-04-20 |
| EP0949919A1 (en) | 1999-10-20 |
| JP4011634B2 (ja) | 2007-11-21 |
| DE69829838T2 (de) | 2006-03-02 |
| WO1999007362A1 (en) | 1999-02-18 |
| CO4960667A1 (es) | 2000-09-25 |
| US6037481A (en) | 2000-03-14 |
| PE108599A1 (es) | 1999-11-22 |
| CA2268030A1 (en) | 1999-02-18 |
| DE69829838D1 (de) | 2005-05-25 |
| JP2001501976A (ja) | 2001-02-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11185478B2 (en) | Buffered microencapsulated compositions and methods | |
| KR0178377B1 (ko) | 사용직전에혼합될수있는친수성담체및비타민c를갖는피부병리학적조성물 | |
| AR016806A1 (es) | Procedimiento para la estabilizacion de acido ascorbico levogiro (laa), composicion de laa estabilizado en un medio que contiene agua, emulsion que incluyea dicho laa estabilizado, producto vitaminico que comprende a dicha composicion, procedimiento para preparar dicha composicion y metodo para el t | |
| US7211249B2 (en) | Heat-generating composition for topical application to skin | |
| CN104870179B (zh) | 缓冲微囊组合物及方法 | |
| BR0012136A (pt) | Inibidores de reabsorção de norepinefrina altamente seletivos e métodos de uso dos mesmos | |
| EP2583665A2 (en) | Cosmetic composition containing retinol stabilized by porous polymer beads and nanoemulsion | |
| KR19990064336A (ko) | 경피투여를 위한 조성물 | |
| JP2004203893A (ja) | ベツリン酸を含む化粧品組成物 | |
| US6110476A (en) | System for stabilizing ascorbic acid based on a phosphonic acid derivative and on a metabisulfite | |
| CA2504361A1 (en) | Formulations containing melatonin, ginkgo biloba, and biotin | |
| JP2019026641A (ja) | 外用組成物、外用組成物の安定化方法及び混合製剤用組成物 | |
| CA2419877C (en) | Storage stable tretinoin and 4-hydroxy anisole containing topical composition | |
| US6239174B1 (en) | Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields | |
| AU744295B2 (en) | Composition and method for treatment of aging skin | |
| US7109237B2 (en) | Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields | |
| EP1765259B1 (en) | Cosmetic compositions and methods for sensory cooling | |
| JP2005343834A (ja) | 皮膚外用剤 | |
| KR100561691B1 (ko) | 수상에서 비타민 c를 안정화시키기 위한 조성물 및 이를이용한 비타민 c의 안정화 방법 | |
| US20030149102A1 (en) | Composition containing stabilized ascorbic acid, and uses thereof | |
| KR100966919B1 (ko) | 코팅된 항산화제 입자를 포함하는 수계 화장료 조성물 및상기 코팅된 항산화제 입자의 제조 방법 | |
| KR100198508B1 (ko) | 폴리락트산-알부틴 화장료 조성물 | |
| JPH0193509A (ja) | 皮膚外用剤 | |
| JP7060860B2 (ja) | 分子内ジスルフィド結合形成能を有するペプチドの利用 | |
| KR20250019808A (ko) | 안티에이징 효과를 지닌 화장료 조성물 및 이의 제조 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |