AR015465A1 - Una formulacion parenteral que comprende 5h-dibenz (b,f)azepin-5-carboxamida y agua o un solvente basado en agua, una forma de dosificacion unitaria y unrecipiente que los comprende y el uso de dicha formulacion para la preparacion de un medicamento - Google Patents
Una formulacion parenteral que comprende 5h-dibenz (b,f)azepin-5-carboxamida y agua o un solvente basado en agua, una forma de dosificacion unitaria y unrecipiente que los comprende y el uso de dicha formulacion para la preparacion de un medicamentoInfo
- Publication number
- AR015465A1 AR015465A1 ARP980105003A ARP980105003A AR015465A1 AR 015465 A1 AR015465 A1 AR 015465A1 AR P980105003 A ARP980105003 A AR P980105003A AR P980105003 A ARP980105003 A AR P980105003A AR 015465 A1 AR015465 A1 AR 015465A1
- Authority
- AR
- Argentina
- Prior art keywords
- water
- formulation
- dibenz
- azepin
- carboxamide
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- ZFXVFMBOFIEPII-UHFFFAOYSA-N 1h-azepine-4-carboxamide Chemical compound NC(=O)C1=CC=CNC=C1 ZFXVFMBOFIEPII-UHFFFAOYSA-N 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002552 dosage form Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000002904 solvent Substances 0.000 title abstract 2
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001037 epileptic effect Effects 0.000 abstract 1
- 230000007928 solubilization Effects 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Una formulacion parental que comprende una 5H-dibenz(b,f)azepin-5-carboxamida y agua o un solvente basado en agua, donde la formulacion no contiene otrosauxiliares de solubilizacion. La formulacion parenteral es util en el tratamiento de ataques resultantes de por ejemplo, ataque epiléptico. Además se describeuna forma de dosificacion unitaria y un recipiente que comprende una cantidad terapéuticamente efectiva de 5H dibenz(b,f)azepin-5-carboxamida y el uso de dichaformulacion parenteral para lapreparacion de un medicamento
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9721497.7A GB9721497D0 (en) | 1997-10-09 | 1997-10-09 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015465A1 true AR015465A1 (es) | 2001-05-02 |
Family
ID=10820342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980105003A AR015465A1 (es) | 1997-10-09 | 1998-10-07 | Una formulacion parenteral que comprende 5h-dibenz (b,f)azepin-5-carboxamida y agua o un solvente basado en agua, una forma de dosificacion unitaria y unrecipiente que los comprende y el uso de dicha formulacion para la preparacion de un medicamento |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US6316417B1 (es) |
| EP (1) | EP1033988B1 (es) |
| JP (2) | JP2001519395A (es) |
| KR (1) | KR100760326B1 (es) |
| CN (1) | CN1210032C (es) |
| AR (1) | AR015465A1 (es) |
| AT (1) | ATE257383T1 (es) |
| AU (1) | AU748034B2 (es) |
| BR (1) | BR9812861A (es) |
| CA (1) | CA2304661C (es) |
| CO (2) | CO5090854A1 (es) |
| CZ (1) | CZ298900B6 (es) |
| DE (1) | DE69821024T2 (es) |
| DK (1) | DK1033988T3 (es) |
| ES (1) | ES2214738T3 (es) |
| GB (1) | GB9721497D0 (es) |
| HU (1) | HU226106B1 (es) |
| ID (1) | ID24134A (es) |
| IL (1) | IL135123A0 (es) |
| MY (1) | MY122129A (es) |
| NO (1) | NO327263B1 (es) |
| NZ (1) | NZ503526A (es) |
| PE (1) | PE121998A1 (es) |
| PL (1) | PL192287B1 (es) |
| PT (1) | PT1033988E (es) |
| RU (1) | RU2242231C2 (es) |
| SK (1) | SK286253B6 (es) |
| TR (1) | TR200000870T2 (es) |
| TW (1) | TW584563B (es) |
| WO (1) | WO1999018966A1 (es) |
| ZA (1) | ZA989183B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
| US20100204178A1 (en) | 2006-10-02 | 2010-08-12 | James Cloyd | Novel parenteral carbamazepine formulation |
| CA2624463C (en) * | 2005-09-30 | 2017-02-14 | Ovation Pharmaceuticals, Inc. | Novel parenteral carbamazepine formulation |
| WO2007092620A2 (en) * | 2006-02-09 | 2007-08-16 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
| US8372431B2 (en) | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
| CN101711739B (zh) * | 2008-10-08 | 2012-07-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 卡马西平的口服药物组合物 |
| CN105726466A (zh) * | 2014-12-10 | 2016-07-06 | 辽宁药联制药有限公司 | 一种奥卡西平注射剂及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202311A (en) * | 1988-08-19 | 1993-04-13 | Children's Medical Center Corporation | Stabilized fgf composition |
| EP0435826A1 (de) * | 1989-12-27 | 1991-07-03 | Ciba-Geigy Ag | Intravenöse Lösungen für Status Epilepticus |
| DE59010072D1 (de) * | 1989-12-27 | 1996-02-29 | Ciba Geigy Ag | Vorrichtung zum Homogenisieren der inhomogenen Lichtverteilung eines Laserstrahllichtbündels |
| US5284662A (en) * | 1990-10-01 | 1994-02-08 | Ciba-Geigy Corp. | Oral osmotic system for slightly soluble active agents |
| RU2020972C1 (ru) * | 1991-02-07 | 1994-10-15 | Мегдятов Рашид Салехович | Способ лечения невралгии тройничного нерва |
| US5231089A (en) * | 1991-12-02 | 1993-07-27 | University Of Florida | Method of improving oral bioavailability of carbamazepine |
| FR2702148B1 (fr) | 1993-03-05 | 1995-04-07 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement du neuro-sida. |
| US5472714A (en) * | 1993-09-08 | 1995-12-05 | Ciba-Geigy Corporation | Double-layered oxcarbazepine tablets |
| US5466683A (en) * | 1994-08-25 | 1995-11-14 | Teva Pharmaceutical Industries Ltd. | Water-soluble analogs of carbamazepine |
-
1997
- 1997-10-09 GB GBGB9721497.7A patent/GB9721497D0/en not_active Ceased
-
1998
- 1998-09-17 TW TW087115501A patent/TW584563B/zh not_active IP Right Cessation
- 1998-10-05 CO CO98057677D patent/CO5090854A1/es unknown
- 1998-10-05 CO CO98057677A patent/CO4950520A1/es unknown
- 1998-10-07 AU AU96298/98A patent/AU748034B2/en not_active Ceased
- 1998-10-07 KR KR1020007003210A patent/KR100760326B1/ko not_active Expired - Fee Related
- 1998-10-07 US US09/509,973 patent/US6316417B1/en not_active Expired - Fee Related
- 1998-10-07 BR BR9812861-2A patent/BR9812861A/pt not_active Application Discontinuation
- 1998-10-07 SK SK505-2000A patent/SK286253B6/sk not_active IP Right Cessation
- 1998-10-07 CZ CZ20001279A patent/CZ298900B6/cs not_active IP Right Cessation
- 1998-10-07 IL IL13512398A patent/IL135123A0/xx unknown
- 1998-10-07 AT AT98950110T patent/ATE257383T1/de not_active IP Right Cessation
- 1998-10-07 TR TR2000/00870T patent/TR200000870T2/xx unknown
- 1998-10-07 PE PE1998000950A patent/PE121998A1/es not_active Application Discontinuation
- 1998-10-07 HU HU0004362A patent/HU226106B1/hu not_active IP Right Cessation
- 1998-10-07 WO PCT/EP1998/006382 patent/WO1999018966A1/en not_active Ceased
- 1998-10-07 DK DK98950110T patent/DK1033988T3/da active
- 1998-10-07 DE DE69821024T patent/DE69821024T2/de not_active Expired - Lifetime
- 1998-10-07 ID IDW20000588A patent/ID24134A/id unknown
- 1998-10-07 RU RU2000110741/15A patent/RU2242231C2/ru not_active IP Right Cessation
- 1998-10-07 PL PL339446A patent/PL192287B1/pl not_active IP Right Cessation
- 1998-10-07 JP JP2000515601A patent/JP2001519395A/ja not_active Withdrawn
- 1998-10-07 CN CNB988099888A patent/CN1210032C/zh not_active Expired - Fee Related
- 1998-10-07 NZ NZ503526A patent/NZ503526A/xx unknown
- 1998-10-07 PT PT98950110T patent/PT1033988E/pt unknown
- 1998-10-07 ES ES98950110T patent/ES2214738T3/es not_active Expired - Lifetime
- 1998-10-07 CA CA002304661A patent/CA2304661C/en not_active Expired - Fee Related
- 1998-10-07 MY MYPI98004586A patent/MY122129A/en unknown
- 1998-10-07 AR ARP980105003A patent/AR015465A1/es unknown
- 1998-10-07 EP EP98950110A patent/EP1033988B1/en not_active Expired - Lifetime
- 1998-10-08 ZA ZA989183A patent/ZA989183B/xx unknown
-
2000
- 2000-04-04 NO NO20001730A patent/NO327263B1/no not_active IP Right Cessation
-
2001
- 2001-11-09 US US10/037,090 patent/US6458770B1/en not_active Expired - Fee Related
-
2005
- 2005-05-06 JP JP2005135218A patent/JP2005281314A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |