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AR015311A1 - Compuestos diaril selenuros, composiciones farmaceuticas y composiciones cosmeticas que comprenden al menos uno de dichos compuestos y utilizacion de la composicion cosmetica - Google Patents

Compuestos diaril selenuros, composiciones farmaceuticas y composiciones cosmeticas que comprenden al menos uno de dichos compuestos y utilizacion de la composicion cosmetica

Info

Publication number
AR015311A1
AR015311A1 ARP990102753A ARP990102753A AR015311A1 AR 015311 A1 AR015311 A1 AR 015311A1 AR P990102753 A ARP990102753 A AR P990102753A AR P990102753 A ARP990102753 A AR P990102753A AR 015311 A1 AR015311 A1 AR 015311A1
Authority
AR
Argentina
Prior art keywords
radical
hydrogen atom
given below
lower alkyl
iii
Prior art date
Application number
ARP990102753A
Other languages
English (en)
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9527328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR015311(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of AR015311A1 publication Critical patent/AR015311A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00Compounds containing selenium
    • C07C391/02Compounds containing selenium having selenium atoms bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compuestos diaril selenuros que responden a la formula general (I) en la que R representa:(i)el radical-CH3, (ii) el radical CH2-O-R5 (iii)el radical -COR6teniendo R5 y R6 los significados dados a continuacion: Ar representa un radical elelgido entrelos radicales de formulas (a)-(e) , teniendo R7 el significadodado aa continuacion, -R2 y R3 idénticos o diferentes representan independientemente un radical elegido entre: (i) un átomo de hidrogeno, (ii) un radicalelegido entre los radicales tertiobutilo, 1-metilciclohexilo o 1-Adamantilo, (iii) un radical -OR8, teniendo R8 el significado dado a continuacion, (iv) unradical poliéter, estando entendido que al menos uno de los radicales R2 o R3 representa un radical (ii), R2 y R1 tomados en conjunto pueden formar con elciclo aromático adyacente un ciclo saturado de 5 o 6 eslabones eventualmente sustituidos por grupos metilos y/o eventualmente interrumpidos por un átomo deoxígeno o de azufre. R4 representa un átomo de hidrogeno, un átomo dehalogeno, un radical alquilo inferior, un radical OR9, un radical poliéter, o un radicalCOR10, teniendo R9 y R10 los significados dados a continuacion. R5 representa un átomo de hidrogeno, un radical inferior, o un radical COR11 teniendo R11 elsignificado dado a continuacion. R6 representa un radical elegido entre: (i) un átomo de hidrogeno, (ii) un radical alquilo inferior, (iii) un radical OR12,teniendo R12 el significado dado a continuacion. (iv) un radical de formula (II) teniendo R y R lossignificados dados a continuacion.R7 representa un átomode hidrogeno, un átomo de halogeno, un radical alquilo inferior, un radical nitro, un radical OR13, un radical poliéter o un radical de la formula (III)teniendo R13, R14 y R15 los significados dados a continuacion, R8 representa un átomo de hidrogeno, un radical alquilo inferior, un radical arilo eventualmentesustituido, un radical aralquilo eventualmente sustituido, un radical monohidroxialquilo o polihidroxialquilo o un radical acilo inferior. R9 representa unátomo de hidrogeno, un radical alquilo inferior, un radical arilo eventualmente sustituido, un radical aralquilo eventualmente sustituido , un radical
ARP990102753A 1998-06-12 1999-06-10 Compuestos diaril selenuros, composiciones farmaceuticas y composiciones cosmeticas que comprenden al menos uno de dichos compuestos y utilizacion de la composicion cosmetica AR015311A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9807439A FR2779720B1 (fr) 1998-06-12 1998-06-12 Nouveaux composes diarylselenures et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie

Publications (1)

Publication Number Publication Date
AR015311A1 true AR015311A1 (es) 2001-04-18

Family

ID=9527328

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990102753A AR015311A1 (es) 1998-06-12 1999-06-10 Compuestos diaril selenuros, composiciones farmaceuticas y composiciones cosmeticas que comprenden al menos uno de dichos compuestos y utilizacion de la composicion cosmetica

Country Status (19)

Country Link
US (2) US6992094B1 (es)
EP (1) EP1086080B1 (es)
JP (1) JP3566210B2 (es)
KR (1) KR100429045B1 (es)
CN (1) CN1267418C (es)
AR (1) AR015311A1 (es)
AT (1) ATE274493T1 (es)
AU (1) AU753187B2 (es)
BR (1) BR9911833A (es)
CA (1) CA2334843C (es)
DE (1) DE69919705T2 (es)
DK (1) DK1086080T3 (es)
ES (1) ES2228048T3 (es)
FR (1) FR2779720B1 (es)
IL (1) IL140076A0 (es)
NO (1) NO20006337L (es)
PT (1) PT1086080E (es)
WO (1) WO1999065872A1 (es)
ZA (1) ZA200006518B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT412703B (de) 2001-12-04 2005-06-27 Vis Vitalis Lizenz & Handels Verwendung von selenithältigen präparaten zur topischen oder bukkalen anwendung
FR2840300B1 (fr) * 2002-06-04 2004-07-16 Galderma Res & Dev NOUVEAUX LIGANDS INHIBITEURS DES RECEPTEURS RARs, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
JP2006511444A (ja) 2002-06-04 2006-04-06 ガルデルマ・リサーチ・アンド・デヴェロップメント・エス・エヌ・セ Rar受容体の阻害剤であるリガンド
FR2847255B1 (fr) * 2002-11-18 2006-11-17 Galderma Res & Dev Nouveaux ligands antagonistes des recepteurs rars, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
WO2004046096A2 (en) 2002-11-18 2004-06-03 Galderma Research & Development,S.N.C. Novel ligands that are antagonists of raf receptors, process for preparing them and use thereof in human medicine and in cosmetics
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
RU2333214C1 (ru) * 2007-03-14 2008-09-10 Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) Способ получения 1,3-ди (4-r-фенилселено)адамантанов
FR2931661B1 (fr) 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
AT511159A1 (de) 2011-02-16 2012-09-15 Selo Medical Gmbh Pharmazeutische zusammensetzungen enthaltend selenit- oder selenathältige verbindungen
CN103086935B (zh) * 2011-10-28 2015-05-20 沈阳药科大学 二苯硒醚、二苯硒亚砜、二苯硒砜类化合物及其用途
EP3262942A1 (de) * 2016-06-27 2018-01-03 Evonik Degussa GmbH Selenodiaryle zur anwendung als mikrobizid sowie als arzneimittel

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170105B1 (en) * 1984-07-07 1990-10-17 Koichi Prof. Dr. Shudo Benzoic acid derivatives
FR2601670B1 (fr) * 1986-07-17 1988-10-07 Cird Nouveaux derives bicycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique
FR2676439B1 (fr) * 1991-05-13 1994-10-28 Cird Galderma Nouveaux composes bi-aromatiques derives d'un motif salicylique, leur procede de preparation et leur utilisation en medecine humaine et veterinaire ainsi qu'en cosmetique.
ES2149814T3 (es) * 1992-04-22 2000-11-16 Ligand Pharm Inc Compuestos que tienen selectividad para los receptores de retinoides x.
JPH08506323A (ja) * 1992-11-25 1996-07-09 ラ ホヤ キャンサー リサーチ ファウンデーション Rxrホモダイマー形成ならびに架橋二環式芳香族化合物および調節遺伝子発現におけるそれらの使用
JPH08505852A (ja) * 1993-01-11 1996-06-25 リガンド・ファーマシューティカルズ・インコーポレーテッド レチノイドxレセプターに対する選択性を有する化合物
FR2713635B1 (fr) 1993-12-15 1996-01-05 Cird Galderma Nouveaux composés propynyl bi-aromatiques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
FR2719043B1 (fr) 1994-04-26 1996-05-31 Cird Galderma Nouveaux composés bicycliques-aromatiques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
FR2722985B1 (fr) * 1994-07-27 1996-09-13 Cird Galderma Nouvelles compositions a base d'un melange synergetique entre au moins un ligand specifique des rxrs et au moins un ligand specifique de rar-x ou de vdr, et leurs utilisations
AU7598596A (en) * 1995-11-01 1997-05-22 Allergan, Inc. Sulfides, sulfoxides and sulfones disubstituted with a tetrahydronaphthalenyl, chromanyl, thiochromanyl or tetrahydroquinolinyl and substituted phenyl or heteroaryl group, having retinoid-like biological activity
FR2755965B1 (fr) * 1996-11-19 1998-12-18 Cird Galderma Composes biaromatiques, compositions pharmaceutiques et cosmetiques les contenant et utilisations

Also Published As

Publication number Publication date
DE69919705T2 (de) 2005-09-15
KR20010052781A (ko) 2001-06-25
ZA200006518B (en) 2001-07-30
BR9911833A (pt) 2001-09-25
KR100429045B1 (ko) 2004-04-29
ATE274493T1 (de) 2004-09-15
US6992094B1 (en) 2006-01-31
FR2779720B1 (fr) 2002-08-16
JP2002518371A (ja) 2002-06-25
AU4049199A (en) 2000-01-05
AU753187B2 (en) 2002-10-10
CA2334843A1 (fr) 1999-12-23
DK1086080T3 (da) 2005-01-17
JP3566210B2 (ja) 2004-09-15
NO20006337L (no) 2001-02-12
IL140076A0 (en) 2002-02-10
EP1086080A1 (fr) 2001-03-28
US20060014803A1 (en) 2006-01-19
CN1267418C (zh) 2006-08-02
EP1086080B1 (fr) 2004-08-25
ES2228048T3 (es) 2005-04-01
CN1305458A (zh) 2001-07-25
WO1999065872A1 (fr) 1999-12-23
PT1086080E (pt) 2004-12-31
FR2779720A1 (fr) 1999-12-17
CA2334843C (fr) 2006-11-21
NO20006337D0 (no) 2000-12-12
DE69919705D1 (de) 2004-09-30

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