AR003421A1 - Mezclas de bencimidazoles sustituidos, un proceso para su preparacion y el uso de los mismos para preparar agentes contra protozoos parasitarios - Google Patents
Mezclas de bencimidazoles sustituidos, un proceso para su preparacion y el uso de los mismos para preparar agentes contra protozoos parasitariosInfo
- Publication number
- AR003421A1 AR003421A1 ARP960102728A AR10272896A AR003421A1 AR 003421 A1 AR003421 A1 AR 003421A1 AR P960102728 A ARP960102728 A AR P960102728A AR 10272896 A AR10272896 A AR 10272896A AR 003421 A1 AR003421 A1 AR 003421A1
- Authority
- AR
- Argentina
- Prior art keywords
- mixtures
- preparation
- parasitic protozoa
- substituted benzimidazoles
- same
- Prior art date
Links
- 150000001556 benzimidazoles Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000003071 parasitic effect Effects 0.000 title abstract 2
- LCTXBFGHZLGBNU-UHFFFAOYSA-M amprolium Chemical compound [Cl-].NC1=NC(CCC)=NC=C1C[N+]1=CC=CC=C1C LCTXBFGHZLGBNU-UHFFFAOYSA-M 0.000 abstract 3
- 229960003683 amprolium Drugs 0.000 abstract 3
- NHZLNPMOSADWGC-UHFFFAOYSA-N 4-amino-N-(2-quinoxalinyl)benzenesulfonamide Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CN=C(C=CC=C2)C2=N1 NHZLNPMOSADWGC-UHFFFAOYSA-N 0.000 abstract 2
- ZDPIZLCVJAAHHR-UHFFFAOYSA-N Clopidol Chemical compound CC1=NC(C)=C(Cl)C(O)=C1Cl ZDPIZLCVJAAHHR-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229960000731 clopidol Drugs 0.000 abstract 2
- JHAYEQICABJSTP-UHFFFAOYSA-N decoquinate Chemical compound N1C=C(C(=O)OCC)C(=O)C2=C1C=C(OCC)C(OCCCCCCCCCC)=C2 JHAYEQICABJSTP-UHFFFAOYSA-N 0.000 abstract 2
- 229960001878 decoquinate Drugs 0.000 abstract 2
- 229960003097 sulfaquinoxaline Drugs 0.000 abstract 2
- 241000224483 Coccidia Species 0.000 abstract 1
- 208000003495 Coccidiosis Diseases 0.000 abstract 1
- 206010023076 Isosporiasis Diseases 0.000 abstract 1
- 229930182504 Lasalocid Natural products 0.000 abstract 1
- WQGJEAMPBSZCIF-HKSLRPGUSA-N Maduramicin Chemical compound N.O1[C@@H](C)[C@H](OC)[C@@H](OC)C[C@H]1O[C@@H]1[C@H]([C@@]2(C)O[C@H](CC2)[C@@]2(C)O[C@]3(O[C@@H]([C@H](C)[C@@H](O)C3)[C@@H](C)[C@H]3[C@@H]([C@@H](OC)[C@H](C)[C@@](O)(CC(O)=O)O3)OC)CC2)O[C@@H]([C@@H]2[C@H](C[C@@H](C)[C@@](C)(O)O2)C)C1 WQGJEAMPBSZCIF-HKSLRPGUSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 229930191564 Monensin Natural products 0.000 abstract 1
- GAOZTHIDHYLHMS-UHFFFAOYSA-N Monensin A Natural products O1C(CC)(C2C(CC(O2)C2C(CC(C)C(O)(CO)O2)C)C)CCC1C(O1)(C)CCC21CC(O)C(C)C(C(C)C(OC)C(C)C(O)=O)O2 GAOZTHIDHYLHMS-UHFFFAOYSA-N 0.000 abstract 1
- VHKXXVVRRDYCIK-CWCPJSEDSA-N Narasin Chemical compound C[C@H]1C[C@H](C)[C@H]([C@@H](CC)C(O)=O)O[C@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 VHKXXVVRRDYCIK-CWCPJSEDSA-N 0.000 abstract 1
- VHKXXVVRRDYCIK-UHFFFAOYSA-N Narasin Natural products CC1CC(C)C(C(CC)C(O)=O)OC1C(C)C(O)C(C)C(=O)C(CC)C1C(C)CC(C)C2(C=CC(O)C3(OC(C)(CC3)C3OC(C)C(O)(CC)CC3)O2)O1 VHKXXVVRRDYCIK-UHFFFAOYSA-N 0.000 abstract 1
- NNOPDLNHPOLRRE-UHFFFAOYSA-N Nequinate Chemical compound CCCCC1=CC(C(C(C(=O)OC)=CN2)=O)=C2C=C1OCC1=CC=CC=C1 NNOPDLNHPOLRRE-UHFFFAOYSA-N 0.000 abstract 1
- UKHWDRMMMYWSFL-UHFFFAOYSA-N Nicarbazin Chemical compound CC=1C=C(C)NC(=O)N=1.C1=CC([N+](=O)[O-])=CC=C1NC(=O)NC1=CC=C([N+]([O-])=O)C=C1 UKHWDRMMMYWSFL-UHFFFAOYSA-N 0.000 abstract 1
- KQXDHUJYNAXLNZ-XQSDOZFQSA-N Salinomycin Chemical compound O1[C@@H]([C@@H](CC)C(O)=O)CC[C@H](C)[C@@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 KQXDHUJYNAXLNZ-XQSDOZFQSA-N 0.000 abstract 1
- 239000004189 Salinomycin Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- BBMULGJBVDDDNI-OWKLGTHSSA-N lasalocid Chemical compound C([C@@H]1[C@@]2(CC)O[C@@H]([C@H](C2)C)[C@@H](CC)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCC=2C(=C(O)C(C)=CC=2)C(O)=O)C[C@](O)(CC)[C@H](C)O1 BBMULGJBVDDDNI-OWKLGTHSSA-N 0.000 abstract 1
- 229960000320 lasalocid Drugs 0.000 abstract 1
- 229960005358 monensin Drugs 0.000 abstract 1
- GAOZTHIDHYLHMS-KEOBGNEYSA-N monensin A Chemical compound C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(O)=O)O2 GAOZTHIDHYLHMS-KEOBGNEYSA-N 0.000 abstract 1
- 229960001851 narasin Drugs 0.000 abstract 1
- 229940073485 nicarbazin Drugs 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
- 229960001548 salinomycin Drugs 0.000 abstract 1
- 235000019378 salinomycin Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invención se refiere a mezclas de bencimidazoles substituidos (I), en donde R1, R2, R3, R4, R5 y R6 tiene los significados dados en lamemoria descriptiva: con uno o varios de los compuestos siguientes: poliéteres antibióticos comomadu ramicina, Lasalocid, Monensin, Narasin, salinomicina oagente sintéticos contra la coccidiosis, como: Amprolium, Amprolium + Sulfaquinoxalina,Amprolium+Sulfaquinoxalina + Ethobapate, Nicarbazin, Clopidol,Clopidol + Metilbenzoquate,Decoquina te, Arprinocid, Bencenoacetonitrilo, Diclazuril, Toltrazuril, Robenidin, Halofuginon, Zoalen como agentes para lalucha contra protozoos parasitarios, especialmente coccidios, en animales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19519821A DE19519821A1 (de) | 1995-05-31 | 1995-05-31 | Mittel gegen parasitäre Protozoen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR003421A1 true AR003421A1 (es) | 1998-08-05 |
Family
ID=7763229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960102728A AR003421A1 (es) | 1995-05-31 | 1996-05-24 | Mezclas de bencimidazoles sustituidos, un proceso para su preparacion y el uso de los mismos para preparar agentes contra protozoos parasitarios |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6034116A (es) |
| EP (1) | EP0828487B1 (es) |
| JP (1) | JPH11505854A (es) |
| KR (1) | KR100424610B1 (es) |
| CN (1) | CN1196485C (es) |
| AR (1) | AR003421A1 (es) |
| AT (1) | ATE254917T1 (es) |
| AU (1) | AU694663B2 (es) |
| BR (1) | BR9608594B1 (es) |
| CZ (1) | CZ290157B6 (es) |
| DE (2) | DE19519821A1 (es) |
| DK (1) | DK0828487T3 (es) |
| ES (1) | ES2211962T3 (es) |
| HU (1) | HUP9802292A3 (es) |
| NO (1) | NO320712B1 (es) |
| NZ (1) | NZ308526A (es) |
| PL (1) | PL185216B1 (es) |
| SK (1) | SK284508B6 (es) |
| TW (1) | TW403651B (es) |
| WO (1) | WO1996038140A1 (es) |
| ZA (1) | ZA964415B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562829B1 (en) * | 1997-05-23 | 2003-05-13 | Hadasit Medical Research Services & Development Co., Ltd. | Treatment of hepatic cirrhosis |
| DE19824483A1 (de) * | 1998-06-02 | 1999-12-09 | Bayer Ag | Halbfeste wäßrige Zubereitungen für orale Applikation von Toltrazuril-Sulfon |
| DE19831985A1 (de) * | 1998-07-16 | 2000-01-20 | Bayer Ag | Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen |
| NZ510998A (en) * | 1998-10-08 | 2003-02-28 | New Ace Res Company | Triazine based anitcoccidial agents for treating protozoal infections |
| DE19958388A1 (de) * | 1999-12-03 | 2001-06-07 | Bayer Ag | Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten |
| DE10049468A1 (de) * | 2000-10-06 | 2002-04-11 | Bayer Ag | N-Alkoxyalkyl-substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen |
| US20030179058A1 (en) * | 2002-01-18 | 2003-09-25 | Microlab, Inc. | System and method for routing input signals using single pole single throw and single pole double throw latching micro-magnetic switches |
| DE102004042958A1 (de) * | 2004-09-02 | 2006-03-09 | Bayer Healthcare Ag | Neue antiparasitäre Kombination von Wirkstoffen |
| DE102005000746A1 (de) * | 2005-01-05 | 2006-07-13 | Bayer Healthcare Ag | Bekämpfung der Histomoniasis |
| DE102007025908A1 (de) | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
| DE102009038950A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue antiparasitäre Kombination von Wirkstoffen |
| EP3496714A4 (en) | 2016-08-11 | 2020-04-22 | Adamis Pharmaceuticals Corporation | DRUG COMPOSITIONS. |
| US11166464B2 (en) * | 2017-03-06 | 2021-11-09 | The United States Of America, As Represented By The Secretary Of Agriculture | Self-assembled active agents |
| US11564910B2 (en) | 2017-12-08 | 2023-01-31 | Adamis Pharmaceuticals Corporation | Drug compositions |
| US20220000876A1 (en) * | 2018-11-02 | 2022-01-06 | Adamis Pharmaceuticals Corporation | Drug compositions |
| UA129752C2 (uk) * | 2020-07-03 | 2025-07-23 | Ніхон Нохіяку Ко., Лтд. | Протикокцидний засіб |
| CN117534620A (zh) * | 2023-11-10 | 2024-02-09 | 六盘水师范学院 | 一种基于钯催化碳氢键官能化的2-三氟甲基苯并咪唑类化合物制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4237617A1 (de) * | 1992-11-06 | 1994-05-11 | Bayer Ag | Verwendung von substituierten Benzimidazolen |
| US5331003A (en) * | 1993-03-26 | 1994-07-19 | Eli Lilly And Company | Anticoccidial methods |
-
1995
- 1995-05-31 DE DE19519821A patent/DE19519821A1/de not_active Withdrawn
-
1996
- 1996-04-02 TW TW085103825A patent/TW403651B/zh not_active IP Right Cessation
- 1996-05-20 EP EP96919789A patent/EP0828487B1/de not_active Expired - Lifetime
- 1996-05-20 AT AT96919789T patent/ATE254917T1/de not_active IP Right Cessation
- 1996-05-20 JP JP8536141A patent/JPH11505854A/ja not_active Ceased
- 1996-05-20 NZ NZ308526A patent/NZ308526A/xx not_active IP Right Cessation
- 1996-05-20 CN CNB961960787A patent/CN1196485C/zh not_active Expired - Fee Related
- 1996-05-20 CZ CZ19973789A patent/CZ290157B6/cs not_active IP Right Cessation
- 1996-05-20 WO PCT/EP1996/002164 patent/WO1996038140A1/de not_active Ceased
- 1996-05-20 HU HU9802292A patent/HUP9802292A3/hu unknown
- 1996-05-20 DK DK96919789T patent/DK0828487T3/da active
- 1996-05-20 DE DE59610836T patent/DE59610836D1/de not_active Expired - Fee Related
- 1996-05-20 ES ES96919789T patent/ES2211962T3/es not_active Expired - Lifetime
- 1996-05-20 PL PL96323594A patent/PL185216B1/pl not_active IP Right Cessation
- 1996-05-20 AU AU58193/96A patent/AU694663B2/en not_active Ceased
- 1996-05-20 KR KR1019970708524A patent/KR100424610B1/ko not_active Expired - Fee Related
- 1996-05-20 BR BRPI9608594-0A patent/BR9608594B1/pt not_active IP Right Cessation
- 1996-05-20 SK SK1598-97A patent/SK284508B6/sk not_active IP Right Cessation
- 1996-05-20 US US08/952,758 patent/US6034116A/en not_active Expired - Fee Related
- 1996-05-24 AR ARP960102728A patent/AR003421A1/es active IP Right Grant
- 1996-05-30 ZA ZA964415A patent/ZA964415B/xx unknown
-
1997
- 1997-11-26 NO NO19975433A patent/NO320712B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO320712B1 (no) | 2006-01-23 |
| DK0828487T3 (da) | 2004-04-05 |
| ZA964415B (en) | 1997-01-09 |
| NO975433D0 (no) | 1997-11-26 |
| HUP9802292A2 (hu) | 1999-05-28 |
| CN1192682A (zh) | 1998-09-09 |
| TW403651B (en) | 2000-09-01 |
| ES2211962T3 (es) | 2004-07-16 |
| BR9608594A (pt) | 1999-01-05 |
| PL185216B1 (pl) | 2003-04-30 |
| DE59610836D1 (de) | 2004-01-08 |
| MX9709187A (es) | 1998-03-31 |
| JPH11505854A (ja) | 1999-05-25 |
| BR9608594B1 (pt) | 2010-07-27 |
| NO975433L (no) | 1998-01-20 |
| US6034116A (en) | 2000-03-07 |
| CN1196485C (zh) | 2005-04-13 |
| ATE254917T1 (de) | 2003-12-15 |
| AU694663B2 (en) | 1998-07-23 |
| HUP9802292A3 (en) | 2001-04-28 |
| WO1996038140A1 (de) | 1996-12-05 |
| KR100424610B1 (ko) | 2004-07-27 |
| EP0828487A1 (de) | 1998-03-18 |
| NZ308526A (en) | 1999-05-28 |
| DE19519821A1 (de) | 1996-12-05 |
| KR19990022045A (ko) | 1999-03-25 |
| CZ290157B6 (cs) | 2002-06-12 |
| EP0828487B1 (de) | 2003-11-26 |
| AU5819396A (en) | 1996-12-18 |
| PL323594A1 (en) | 1998-04-14 |
| SK284508B6 (sk) | 2005-05-05 |
| SK159897A3 (en) | 1998-09-09 |
| CZ378997A3 (cs) | 1998-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR003421A1 (es) | Mezclas de bencimidazoles sustituidos, un proceso para su preparacion y el uso de los mismos para preparar agentes contra protozoos parasitarios | |
| ES2118835T3 (es) | 2-etil-1h-imidazo(4,5-c)quinolin-4-aminas antiviricas. | |
| IL154925A0 (en) | Modulation of il-2 and il-15-mediated t cell responses | |
| AR039823A1 (es) | Moduladores ureicos derivados de la amino-tetralina del receptor vr1 de vanilloides | |
| AR022860A1 (es) | Derivados de camptotecina que poseen actividad antitumoral | |
| AR007855A1 (es) | Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios, uso en medicinay composiciones farmaceuticas que los contienen | |
| IS6750A (is) | Samrunnin heterósýklísk súkkínímíð efnasambönd oghliðstæður þeirra, stillar fyrir starfsemi kjarnahormónaviðtaka | |
| PT1093819E (pt) | Compostos e composicoes para fornecimento de agentes activos | |
| CO5011096A1 (es) | Medicamentos que contienen antagonistas del receptor 5-ht3 para el tratamiento de la ibs | |
| ES2175079T3 (es) | Derivados de indol utiles como inhibidores de cgmp-pde. | |
| TR199802698T2 (xx) | Valsartan�n kat� oral doz formlar�. | |
| UA41316C2 (uk) | Трициклічні похідні піролу і фармацевтичний препарат | |
| TR200201001T2 (tr) | Pürin türevleri | |
| CY1112815T1 (el) | Ανταγωνιστες υποδοχεα ορμονης απελευθερωσης γοναδοτροπινης και μεθοδοι που σχετιζονται με αυτους | |
| PT1146861E (pt) | Formulacoes de particulas de hidrogel | |
| NO980700D0 (no) | Perifert aktive anti-hyperalgesi opiater | |
| MY131434A (en) | Angiotensin ii antagonists | |
| UA27776C2 (uk) | Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців | |
| MX9200361A (es) | Nuevo uso del antagonista de adenosina. | |
| DE602004020638D1 (de) | Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten | |
| ECSP034766A (es) | Una combinacion que comprende combretastatina y agentes anticancerigenos | |
| TR200200359T2 (tr) | Cgrp Antagonist'lerinin ve cgrp-release (Gevşeme)-Engelleyici Menopoza Bağlı Deri Kızarıklıklarında Kullanılması | |
| DE69330754D1 (de) | 2,5-DIOXO-2,5-DIHYDRO-1H-BENZ[b]AZEPINE ALS NMDA REZEPTOR ANTAGONISTEN | |
| GB1321509A (en) | Azepine derivatives | |
| ES2059534T3 (es) | Nuevos derivados benzopiranos antihipertensivos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |