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AR003271A1 - Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica. - Google Patents

Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica.

Info

Publication number
AR003271A1
AR003271A1 ARP960103997A AR10399796A AR003271A1 AR 003271 A1 AR003271 A1 AR 003271A1 AR P960103997 A ARP960103997 A AR P960103997A AR 10399796 A AR10399796 A AR 10399796A AR 003271 A1 AR003271 A1 AR 003271A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
asthma
molecular weight
low molecular
preparation
Prior art date
Application number
ARP960103997A
Other languages
English (en)
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Publication of AR003271A1 publication Critical patent/AR003271A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un método para el tratamiento de un paciente afectado de asma inducida por antígeno, que ha sido estimulado con un antígeno inductor de asma, quecomprende la administración intrabronquial al paciente de una composición farmacéutica quecontien e entre 0,05 mg aproximadamente y 1,0 mgaproximadamente de heparinas de peso molecular ultrabajo (en inglés ULMWH) por kilogramo de peso del paciente, en cada dosis; dicha ULMWH tiene un pesomolecular promedio de 3.000 daltons ó menos.
ARP960103997A 1995-08-18 1996-08-15 Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica. AR003271A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/516,786 US5690910A (en) 1995-08-18 1995-08-18 Method for treating asthma

Publications (1)

Publication Number Publication Date
AR003271A1 true AR003271A1 (es) 1998-07-08

Family

ID=24057086

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103997A AR003271A1 (es) 1995-08-18 1996-08-15 Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica.

Country Status (21)

Country Link
US (1) US5690910A (es)
EP (1) EP0844869B1 (es)
JP (1) JP3263723B2 (es)
KR (1) KR100451901B1 (es)
AR (1) AR003271A1 (es)
AT (1) ATE300938T1 (es)
AU (1) AU701691B2 (es)
CA (1) CA2229060A1 (es)
CZ (1) CZ292134B6 (es)
DE (1) DE69635023T2 (es)
DK (1) DK0844869T3 (es)
ES (1) ES2244974T3 (es)
HU (1) HUP9901614A3 (es)
IL (1) IL123166A (es)
NZ (2) NZ315275A (es)
PL (1) PL186912B1 (es)
PT (1) PT844869E (es)
SK (1) SK282759B6 (es)
UA (1) UA62919C2 (es)
WO (1) WO1997006783A1 (es)
ZA (1) ZA966838B (es)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980865A (en) * 1995-08-18 1999-11-09 Baker Norton Pharmaceuticals, Inc. Method for treating late phase allergic reactions and inflammatory diseases
US20020086852A1 (en) * 1998-05-14 2002-07-04 Cantor Jerome O. Method for treating respiratory disorders associated with pulmonary elastic fiber injury
CA2341412A1 (en) 1998-08-27 2000-03-09 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase i and ii
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
US6235725B1 (en) * 1998-10-30 2001-05-22 Baker Norton Pharmaceuticals, Inc. Methods and compositions for the prevention of tolerance to medications
SI1124563T1 (en) * 1998-10-30 2005-02-28 Ivax Research, Inc. Methods and compositions for the prevention of tolerance to bronchodilators
EP1190364A2 (en) 1999-04-23 2002-03-27 Massachusetts Institute Of Technology System and method for polymer notation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1266013B1 (en) 2000-03-08 2014-10-15 Massachusetts Institute Of Technology Heparinase iii and uses thereof
ATE426805T1 (de) 2000-09-12 2009-04-15 Massachusetts Inst Technology Verfahren und produkte, die mit niedermolekularem heparin assoziiert sind
EP1328260A2 (en) * 2000-10-18 2003-07-23 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
PT1494732E (pt) 2002-03-20 2008-03-20 Mannkind Corp Aparelho de inalação
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
MX2007001903A (es) 2004-08-20 2007-08-02 Mannkind Corp Catalisis de sintesis de dicetopiperazina.
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
EP1791555B1 (en) * 2004-09-10 2013-03-13 Pharmaorigin ApS Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
US8592393B2 (en) * 2007-11-02 2013-11-26 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US9351992B2 (en) * 2007-11-02 2016-05-31 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
US8569262B2 (en) 2007-11-02 2013-10-29 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
RU2608439C2 (ru) 2008-06-13 2017-01-18 Маннкайнд Корпорейшн Ингалятор для сухого порошка и система для доставки лекарственных средств
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
MX2012006265A (es) * 2009-12-03 2012-07-25 Opko Health Inc Formulaciones disacaridas hipersulfatadas.
BR112012026542A2 (pt) 2010-04-16 2016-07-12 Momenta Pharmaceuticals Inc abordagem seletiva de tecido
CN103096870B (zh) 2010-06-17 2017-04-19 动量制药公司 调节毛发生长的方法和组合物
RU2528093C2 (ru) * 2010-07-21 2014-09-10 Олег Ильич Эпштейн Фармацевтическая композиция и способ лечения острых и хронических заболевания дыхательной системы и синдрома кашля
WO2012058424A1 (en) * 2010-10-29 2012-05-03 Opko Health, Inc. Hypersulfated disaccharides to treat elastase related disorders
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
EP3003324A4 (en) 2013-05-28 2017-01-25 Momenta Pharmaceuticals, Inc. Pharmaceutical compositions
CA2918369C (en) 2013-07-18 2021-06-29 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2018035050A1 (en) 2016-08-16 2018-02-22 Opko Pharmaceuticals, Llc Pure heptasulfated disaccharides having improved oral bioavailability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK140493A3 (en) * 1991-06-10 1994-10-05 Schering Corp Non-chlorofluorocarbon aerosol formulations
AU3938093A (en) * 1992-04-02 1993-11-08 Baker Norton Pharmaceuticals, Inc. Method and composition for treating antigen-induced and exercise-induced asthma

Also Published As

Publication number Publication date
KR100451901B1 (ko) 2005-09-12
PL186912B1 (pl) 2004-03-31
EP0844869A4 (en) 2003-04-09
ATE300938T1 (de) 2005-08-15
IL123166A (en) 2002-07-25
JP3263723B2 (ja) 2002-03-11
UA62919C2 (en) 2004-01-15
EP0844869B1 (en) 2005-08-03
HUP9901614A2 (hu) 1999-09-28
IL123166A0 (en) 1998-09-24
DE69635023D1 (de) 2005-09-08
HK1007060A1 (en) 1999-04-01
SK17298A3 (en) 1998-09-09
MX9801165A (es) 1998-07-31
ES2244974T3 (es) 2005-12-16
CZ48198A3 (cs) 1998-11-11
PT844869E (pt) 2005-10-31
US5690910A (en) 1997-11-25
NZ337996A (en) 2001-04-27
DE69635023T2 (de) 2006-05-24
WO1997006783A1 (en) 1997-02-27
AU701691B2 (en) 1999-02-04
KR19990037688A (ko) 1999-05-25
DK0844869T3 (da) 2005-12-12
HUP9901614A3 (en) 2000-04-28
CZ292134B6 (cs) 2003-08-13
NZ315275A (en) 2000-01-28
AU6694596A (en) 1997-03-12
JPH11511196A (ja) 1999-09-28
PL324970A1 (en) 1998-06-22
SK282759B6 (sk) 2002-12-03
ZA966838B (en) 1997-02-19
CA2229060A1 (en) 1997-02-27
EP0844869A1 (en) 1998-06-03

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