AR008393A3 - Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento - Google Patents
Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimientoInfo
- Publication number
- AR008393A3 AR008393A3 ARP970102613A ARP970102613A AR008393A3 AR 008393 A3 AR008393 A3 AR 008393A3 AR P970102613 A ARP970102613 A AR P970102613A AR P970102613 A ARP970102613 A AR P970102613A AR 008393 A3 AR008393 A3 AR 008393A3
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- compounds
- exclusive use
- alkyl
- preparing aza
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 150000008043 acidic salts Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Proceso para preparar aza ciclohexapéptidos de formula I en donde: R1 es CH2CH2NH2 o CH2-CONH2; R1 es alquil C9-C21, alquenil C9-C21, alcoxifenil C1-C10alcoxinaftil C1-C10; o alcoxiterfenil C1-C10; R11 es H, alquil C1-C4, alquenil C3-C4, (CH2)2-4 OH, o (CH2)2-6NRIVRV, R111 es H, alquil C1-C4 alquenil C3-C4,(CH2)2-4OH, (CH2)2-6NRIVRV, o R11 y R111 tomados juntos son (CH2)4, (CH2)5 (CH2)2O(CH2)2OCH2)2NH(CH2)2; RIV es H O alquil C1-C4, RV es H o alquil C1-C4, Qes N u O o sus sales deadici on de ácido de los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2048396P | 1996-06-14 | 1996-06-14 | |
| GBGB9614325.0A GB9614325D0 (en) | 1996-07-08 | 1996-07-08 | A process for preparing certain aza cyclohexapeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008393A3 true AR008393A3 (es) | 2000-01-19 |
Family
ID=26309664
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970102613A AR008393A3 (es) | 1996-06-14 | 1997-06-13 | Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento |
| ARP980101679A AR017997A3 (es) | 1996-06-14 | 1998-04-13 | Procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980101679A AR017997A3 (es) | 1996-06-14 | 1998-04-13 | Procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0912603B1 (es) |
| JP (1) | JP3089037B2 (es) |
| KR (1) | KR100341953B1 (es) |
| CN (1) | CN1122672C (es) |
| AR (2) | AR008393A3 (es) |
| AT (1) | ATE252112T1 (es) |
| AU (1) | AU712857B2 (es) |
| BR (1) | BR9709691B1 (es) |
| CA (1) | CA2256620C (es) |
| CZ (2) | CZ287742B6 (es) |
| DE (1) | DE69725580T2 (es) |
| DK (1) | DK0912603T3 (es) |
| EA (1) | EA002049B1 (es) |
| ES (1) | ES2208914T3 (es) |
| HR (1) | HRP970318B1 (es) |
| HU (1) | HU227427B1 (es) |
| NZ (1) | NZ332798A (es) |
| PL (1) | PL187035B1 (es) |
| PT (1) | PT912603E (es) |
| RS (1) | RS49572B (es) |
| SI (1) | SI0912603T1 (es) |
| SK (1) | SK284043B6 (es) |
| TW (1) | TW450975B (es) |
| UA (1) | UA54433C2 (es) |
| WO (1) | WO1997047645A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2340647A1 (en) * | 1998-08-28 | 2000-03-09 | Eli Lilly And Company | Reversible boronate complexes of 1,2-cis-diol cyclic-peptides |
| EP1785432A1 (en) | 2005-11-15 | 2007-05-16 | Sandoz AG | Process and intermediates for the synthesis of caspofungin. |
| WO2008012310A1 (en) | 2006-07-26 | 2008-01-31 | Sandoz Ag | Caspofungin formulations |
| US8048853B2 (en) * | 2008-06-13 | 2011-11-01 | Xellia Pharmaceuticals Aps | Process for preparing pharmaceutical compound and intermediates thereof |
| EP2240507A2 (en) * | 2008-06-25 | 2010-10-20 | TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Processes for preparing high purity aza cyclohexapeptides |
| CN101648994B (zh) * | 2009-08-06 | 2012-09-05 | 上海天伟生物制药有限公司 | 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途 |
| CN101792486A (zh) * | 2010-04-12 | 2010-08-04 | 浙江海正药业股份有限公司 | 一种合成醋酸卡泊芬净的方法 |
| CN102367269B (zh) | 2010-11-10 | 2013-11-06 | 上海天伟生物制药有限公司 | 一种卡泊芬净类似物及其制备方法和用途 |
| CN102367268B (zh) | 2010-11-10 | 2013-11-06 | 上海天伟生物制药有限公司 | 一种卡泊芬净类似物及其用途 |
| CN102367267B (zh) | 2010-11-10 | 2013-09-04 | 上海天伟生物制药有限公司 | 一种卡泊芬净的制备方法 |
| CN102219833A (zh) * | 2011-04-18 | 2011-10-19 | 深圳市健元医药科技有限公司 | 一种更加安全的棘白菌类抗真菌药的制备方法 |
| CN102746384B (zh) | 2011-04-22 | 2016-01-20 | 上海天伟生物制药有限公司 | 一种高纯度的卡泊芬净或其盐及其制备方法和用途 |
| CN107778360B (zh) * | 2016-08-27 | 2020-06-12 | 鲁南制药集团股份有限公司 | 一种制备醋酸卡泊芬净的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
| US5516756A (en) | 1994-10-31 | 1996-05-14 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
| US5552521A (en) * | 1995-02-10 | 1996-09-03 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
| AR006598A1 (es) | 1996-04-19 | 1999-09-08 | Merck Sharp & Dohme | "composiciones anti-fungosas, su uso en la manufactura de medicamentos y un procedimiento para su preparación" |
-
1997
- 1997-06-09 HR HR970318A patent/HRP970318B1/xx not_active IP Right Cessation
- 1997-06-10 NZ NZ332798A patent/NZ332798A/xx not_active IP Right Cessation
- 1997-06-10 WO PCT/US1997/009833 patent/WO1997047645A1/en not_active Ceased
- 1997-06-10 CA CA002256620A patent/CA2256620C/en not_active Expired - Lifetime
- 1997-06-10 JP JP10501708A patent/JP3089037B2/ja not_active Expired - Lifetime
- 1997-06-10 HU HU9903678A patent/HU227427B1/hu not_active IP Right Cessation
- 1997-06-10 SK SK1694-98A patent/SK284043B6/sk not_active IP Right Cessation
- 1997-06-10 AU AU33039/97A patent/AU712857B2/en not_active Expired
- 1997-06-10 EA EA199900027A patent/EA002049B1/ru not_active IP Right Cessation
- 1997-06-10 EP EP97928884A patent/EP0912603B1/en not_active Expired - Lifetime
- 1997-06-10 PL PL97330400A patent/PL187035B1/pl unknown
- 1997-06-10 PT PT97928884T patent/PT912603E/pt unknown
- 1997-06-10 ES ES97928884T patent/ES2208914T3/es not_active Expired - Lifetime
- 1997-06-10 KR KR1019980710154A patent/KR100341953B1/ko not_active Expired - Lifetime
- 1997-06-10 DK DK97928884T patent/DK0912603T3/da active
- 1997-06-10 CZ CZ19984119A patent/CZ287742B6/cs not_active IP Right Cessation
- 1997-06-10 AT AT97928884T patent/ATE252112T1/de active
- 1997-06-10 CN CN97195496A patent/CN1122672C/zh not_active Expired - Lifetime
- 1997-06-10 BR BRPI9709691-1A patent/BR9709691B1/pt not_active IP Right Cessation
- 1997-06-10 TW TW086107988A patent/TW450975B/zh not_active IP Right Cessation
- 1997-06-10 DE DE69725580T patent/DE69725580T2/de not_active Expired - Lifetime
- 1997-06-10 SI SI9730589T patent/SI0912603T1/xx unknown
- 1997-06-13 AR ARP970102613A patent/AR008393A3/es active IP Right Grant
- 1997-10-06 UA UA99010195A patent/UA54433C2/uk unknown
-
1998
- 1998-04-13 AR ARP980101679A patent/AR017997A3/es active IP Right Grant
- 1998-12-07 RS YUP-560/98A patent/RS49572B/sr unknown
-
2000
- 2000-06-22 CZ CZ20002362A patent/CZ287743B6/cs not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |