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AR007739A1 - A PROCESS FOR THE PREPARATION OF N- (R) - (2-HYDROXY-2-PIRIDINE-3-IL-ETIL) -2- (4-NITRO-PHENYL) -ACETAMIDE - Google Patents

A PROCESS FOR THE PREPARATION OF N- (R) - (2-HYDROXY-2-PIRIDINE-3-IL-ETIL) -2- (4-NITRO-PHENYL) -ACETAMIDE

Info

Publication number
AR007739A1
AR007739A1 ARP970103145A ARP970103145A AR007739A1 AR 007739 A1 AR007739 A1 AR 007739A1 AR P970103145 A ARP970103145 A AR P970103145A AR P970103145 A ARP970103145 A AR P970103145A AR 007739 A1 AR007739 A1 AR 007739A1
Authority
AR
Argentina
Prior art keywords
acetamide
hydroxy
preparation
piridine
etil
Prior art date
Application number
ARP970103145A
Other languages
Spanish (es)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9616805.9A external-priority patent/GB9616805D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of AR007739A1 publication Critical patent/AR007739A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)

Abstract

Un proceso para la preparación de N-(R)-(2-hidroxi-2-piridina-3-il-metil)-2 -(4-nitrofenil)-acetamida de fórmula estructural I que comprende incubar unsustrato de fórmula estructural III con una levadura en medio nutriente.A process for the preparation of N- (R) - (2-hydroxy-2-pyridine-3-yl-methyl) -2 - (4-nitrophenyl) -acetamide of structural formula I comprising incubating a substrate of structural formula III with a yeast in nutrient medium.

ARP970103145A 1996-07-22 1997-07-14 A PROCESS FOR THE PREPARATION OF N- (R) - (2-HYDROXY-2-PIRIDINE-3-IL-ETIL) -2- (4-NITRO-PHENYL) -ACETAMIDE AR007739A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2205596P 1996-07-22 1996-07-22
GBGB9616805.9A GB9616805D0 (en) 1996-08-09 1996-08-09 N-(R)-(2-hydroxy-2-pyridine-3-yl-ethyl)-2-(4-nitrophenyl)-acetamide

Publications (1)

Publication Number Publication Date
AR007739A1 true AR007739A1 (en) 1999-11-10

Family

ID=26309849

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970103145A AR007739A1 (en) 1996-07-22 1997-07-14 A PROCESS FOR THE PREPARATION OF N- (R) - (2-HYDROXY-2-PIRIDINE-3-IL-ETIL) -2- (4-NITRO-PHENYL) -ACETAMIDE

Country Status (3)

Country Link
AR (1) AR007739A1 (en)
AU (1) AU3804697A (en)
WO (1) WO1998003672A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010102198A (en) * 1999-02-16 2001-11-15 후루타 타케시 SUBSTITUTED ACETYLPYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR OPTICALLY ACTIVE β3 AGONIST BY THE USE OF THE SAME
US7129067B2 (en) * 2002-06-28 2006-10-31 Takasago International Corporation Method for producing lactone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3638759A1 (en) * 1986-11-13 1988-06-09 Schering Ag STEREO-SPECIFIC KETOR REDUCTION OF BICYCLOOCTANDION-CARBONIC ACID ESTERS BY MICRO-ORGANISMS
EP0538693A3 (en) * 1991-10-23 1994-08-17 Squibb & Sons Inc Stereoselective preparation of halophenyl alcohols
IL113410A (en) * 1994-04-26 1999-11-30 Merck & Co Inc Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them
US5491077A (en) * 1994-07-20 1996-02-13 Merck & Co., Inc. Microbial method

Also Published As

Publication number Publication date
AU3804697A (en) 1998-02-10
WO1998003672A1 (en) 1998-01-29

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AR007739A1 (en) A PROCESS FOR THE PREPARATION OF N- (R) - (2-HYDROXY-2-PIRIDINE-3-IL-ETIL) -2- (4-NITRO-PHENYL) -ACETAMIDE