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AR004860A1 - Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal - Google Patents

Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal

Info

Publication number
AR004860A1
AR004860A1 ARP960105500A ARP960105500A AR004860A1 AR 004860 A1 AR004860 A1 AR 004860A1 AR P960105500 A ARP960105500 A AR P960105500A AR P960105500 A ARP960105500 A AR P960105500A AR 004860 A1 AR004860 A1 AR 004860A1
Authority
AR
Argentina
Prior art keywords
antibodies
receptor
sequence
abnormal
police
Prior art date
Application number
ARP960105500A
Other languages
English (en)
Original Assignee
Dupuis Laurent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9485198&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR004860(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dupuis Laurent filed Critical Dupuis Laurent
Publication of AR004860A1 publication Critical patent/AR004860A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un polipeptido purificado que comprende una secuencia de aminoácidos elegida entre a) la secuencia SEC ID N°2, b) toda la secuencia biológicamenteactiva derivada del SEC ID n°2. Se proporciona además, un método para producirlo, unmé todo para identificarlo y/o aislarlo, una composiciónfarmacéutica que lo comprende, un ligando o mudulador de dicho péptido, la secuencia nucléicos aislada que codifica a dicho péptido. También seproporciona un vector que contiene a dichasecuen cia, la utilización que dicho vector para transfectar una célula huésped, una sonda nucleotídica, unasecuencia antisentido y anticuerpos. Además se describen las utilizaciones de dicho polipétido, secuencia sonda y anticuerpos, métodos dediagnóst ico invitro y un kit para el diagnóstico in vitro.
ARP960105500A 1995-12-06 1996-12-05 Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal AR004860A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514424A FR2742156A1 (fr) 1995-12-06 1995-12-06 Polypeptide recepteur de l'il-13
PCT/FR1996/001756 WO1997020926A1 (fr) 1995-12-06 1996-11-07 Polypeptide recepteur de l'il-i3

Publications (1)

Publication Number Publication Date
AR004860A1 true AR004860A1 (es) 1999-03-10

Family

ID=9485198

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP960105500A AR004860A1 (es) 1995-12-06 1996-12-05 Anticuerpos mono o policionales, anticuerpos conjugados, o sus fragmentos, su utilizacion y metodo de diagnostico in vitro de patologias correlacionadas con una expresion anormal del receptor de la il-13, a partir de muestras biologicas susceptibles de contener el receptor de la il-13 expresado a un nivel anormal
ARP060104650A AR056723A2 (es) 1995-12-06 2006-10-25 Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP060104650A AR056723A2 (es) 1995-12-06 2006-10-25 Polipeptido purificado metodo para producirlo , metodo para identificarlo y/ o aislarlo composicion farmaceutica que lo comprende, secuencia de acidos nucleicos aislada que codifica dicho polipeptido, vector que contiene a dicha secuencia celula huesped transfectada por dicho vector, sonda nucleotid

Country Status (19)

Country Link
US (4) US7928073B2 (es)
EP (1) EP0876482B1 (es)
JP (3) JP3415162B2 (es)
AR (2) AR004860A1 (es)
AT (1) ATE234922T1 (es)
AU (1) AU7576096A (es)
BR (1) BR9611697B1 (es)
CA (1) CA2238893C (es)
DE (1) DE69626859T2 (es)
DK (1) DK0876482T3 (es)
ES (1) ES2192620T3 (es)
FR (1) FR2742156A1 (es)
MX (1) MX9804419A (es)
MY (1) MY123740A (es)
NO (3) NO324775B1 (es)
PT (1) PT876482E (es)
TW (1) TW565570B (es)
WO (1) WO1997020926A1 (es)
ZA (1) ZA9610238B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2238080C (en) * 1995-10-23 2012-03-13 Amrad Operations Pty. Ltd. A novel haemopoietin receptor and genetic sequences encoding same
US6911530B1 (en) 1995-10-23 2005-06-28 Amrad Operations, Pty., Ltd. Haemopoietin receptor and genetic sequences encoding same
US7078494B1 (en) 1996-03-01 2006-07-18 Genetics Institute, Llc Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding
US5710023A (en) 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain
EP0812913A3 (en) * 1996-06-12 1999-08-04 Smithkline Beecham Corporation HR-1 receptor, a receptor of the cytokine receptors family
WO1998010638A1 (en) * 1996-09-10 1998-03-19 Amrad Operations Pty. Ltd. Therapeutic molecules
GB9625899D0 (en) * 1996-12-13 1997-01-29 Glaxo Group Ltd Substances and their uses
US6743604B1 (en) 1996-12-13 2004-06-01 Smithkline Beecham Corporation Substances and their uses
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
US7189400B2 (en) 1998-03-17 2007-03-13 Genetics Institute, Llc Methods of treatment with antagonists of MU-1
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
WO2000036103A1 (en) 1998-12-14 2000-06-22 Genetics Institute, Inc. Cytokine receptor chain
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
US20020197266A1 (en) * 2000-02-08 2002-12-26 Waldemar Debinski Immunotherapy using interleukin 13 receptor subunit alpha 2
WO2001077332A2 (en) * 2000-04-07 2001-10-18 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
EA011686B1 (ru) 2002-07-15 2009-04-28 Уайт Способ модуляции развития и функций т-клеток-хелперов
ES2385038T3 (es) 2003-12-23 2012-07-17 Genentech, Inc. Nuevos anticuerpos Anti-IL 13 y usos de los mismos
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
MX2007005083A (es) 2004-10-29 2007-10-03 Topigen Pharmaceuticals Inc Oligonucleotidos antisentido para tratar alergias y proliferacion celular neoplastica.
JP2008520684A (ja) 2004-11-17 2008-06-19 アブジェニックス・インコーポレーテッド Ｉｌ−１３に対する完全ヒトモノクローナル抗体
GB0615881D0 (en) * 2006-08-10 2006-09-20 Univ Southampton Novel peptide for treatment of asthma
CA2685123A1 (en) * 2007-04-23 2008-10-30 Wyeth Methods and compositions for treating and monitoring treatment of il-13-associated disorders
EP2850093B1 (en) 2012-01-27 2019-01-09 The Board of Trustees of the Leland Stanford Junior University Therapeutic il-13 polypeptides
US9738696B2 (en) 2012-08-09 2017-08-22 The Board Of Trustees Of The Leland Stanford Junior University Superkines and synthekines: repurposed cytokines with new and enhanced signaling activities
EP2970492B1 (en) 2013-03-15 2019-05-08 Wake Forest University Health Sciences Antibodies against human and canine il-13ra2
PL3044323T3 (pl) 2013-09-13 2022-06-27 F.Hoffmann-La Roche Ag Sposoby wykrywania i ilościowego oznaczania białka komórki gospodarza w liniach komórkowych
MY193481A (en) 2013-09-13 2022-10-17 Genentech Inc Method and compositions comprising purified recombinant polypeptides
JP6936934B2 (ja) 2013-09-24 2021-09-22 メディシナ セラピューティクス インコーポレイテッド インターロイキン−４受容体結合融合タンパク質及びその使用
EP3694558B1 (en) 2017-10-10 2024-04-10 Medicenna Therapeutics Inc. Il-4-fusion formulations for treatment of central nervous system (cns) tumors
WO2019239213A2 (en) 2018-06-01 2019-12-19 Medicenna Therapeutics Inc. Uses and methods for oncolytic virus targeting of il-4/il-13 and fusions thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5596072A (en) * 1992-08-21 1997-01-21 Schering Corporation Method of refolding human IL-13
US5587459A (en) * 1994-08-19 1996-12-24 Regents Of The University Of Minnesota Immunoconjugates comprising tyrosine kinase inhibitors
US6911530B1 (en) * 1995-10-23 2005-06-28 Amrad Operations, Pty., Ltd. Haemopoietin receptor and genetic sequences encoding same
US5710023A (en) * 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain

Also Published As

Publication number Publication date
US20050282216A1 (en) 2005-12-22
US8318910B2 (en) 2012-11-27
PT876482E (pt) 2003-07-31
MX9804419A (es) 1998-09-30
MY123740A (en) 2006-06-30
NO331148B1 (no) 2011-10-24
NO982550L (no) 1998-08-05
BR9611697B1 (pt) 2013-09-17
CA2238893A1 (fr) 1997-06-12
JPH11511028A (ja) 1999-09-28
CA2238893C (fr) 2013-10-08
TW565570B (en) 2003-12-11
JP3737793B2 (ja) 2006-01-25
ZA9610238B (en) 1998-06-05
JP4185070B2 (ja) 2008-11-19
US20060035855A1 (en) 2006-02-16
NO20092994L (no) 1998-08-05
EP0876482B1 (fr) 2003-03-19
DE69626859T2 (de) 2003-12-24
DK0876482T3 (da) 2003-07-21
NO20074034L (no) 1998-08-05
EP0876482A1 (fr) 1998-11-11
US20110201029A1 (en) 2011-08-18
ES2192620T3 (es) 2003-10-16
JP2005323595A (ja) 2005-11-24
AR056723A2 (es) 2007-10-17
BR9611697A (pt) 1999-02-17
NO328197B1 (no) 2010-01-04
DE69626859D1 (de) 2003-04-24
ATE234922T1 (de) 2003-04-15
WO1997020926A1 (fr) 1997-06-12
FR2742156A1 (fr) 1997-06-13
JP3415162B2 (ja) 2003-06-09
US7928073B2 (en) 2011-04-19
AU7576096A (en) 1997-06-27
JP2003180382A (ja) 2003-07-02
NO324775B1 (no) 2007-12-10
US20060035856A1 (en) 2006-02-16
NO982550D0 (no) 1998-06-04

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