AR004088A1 - Gonadotropinas compuestas por una subunidad alfa y una subunidad beta - Google Patents
Gonadotropinas compuestas por una subunidad alfa y una subunidad betaInfo
- Publication number
- AR004088A1 AR004088A1 ARP960104879A ARP960104879A AR004088A1 AR 004088 A1 AR004088 A1 AR 004088A1 AR P960104879 A ARP960104879 A AR P960104879A AR P960104879 A ARP960104879 A AR P960104879A AR 004088 A1 AR004088 A1 AR 004088A1
- Authority
- AR
- Argentina
- Prior art keywords
- gonadotropins
- subunit
- beta
- alpha
- alpha subunit
- Prior art date
Links
- 102000006771 Gonadotropins Human genes 0.000 title abstract 5
- 108010086677 Gonadotropins Proteins 0.000 title abstract 5
- 239000002622 gonadotropin Substances 0.000 title abstract 5
- 229940094892 gonadotropins Drugs 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a gonadotropinas compuestas por una subunidad alfa y una subunidad beta, comprendiendo dicha gonadotropinaspuentes disulfuro no nativos, preferentemente puentes disulfuro intersubunidades nonat ivos. Las gonadotropinas de acuerdo con la invencióntienen una estabilidad mejorada. La presente invención provee además composiciones farmacéuticas que comprenden dichas gonadotropinas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95202876 | 1995-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR004088A1 true AR004088A1 (es) | 1998-09-30 |
Family
ID=8220762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960104879A AR004088A1 (es) | 1995-10-24 | 1996-10-24 | Gonadotropinas compuestas por una subunidad alfa y una subunidad beta |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5691455A (es) |
| EP (1) | EP0785215B1 (es) |
| JP (1) | JP4086922B2 (es) |
| KR (1) | KR100498532B1 (es) |
| CN (1) | CN1161381C (es) |
| AR (1) | AR004088A1 (es) |
| AT (1) | ATE218584T1 (es) |
| AU (1) | AU711081B2 (es) |
| BR (1) | BR9605220B1 (es) |
| CA (1) | CA2188508C (es) |
| DE (1) | DE69621577T2 (es) |
| DK (1) | DK0785215T3 (es) |
| ES (1) | ES2177721T3 (es) |
| HU (1) | HU222043B1 (es) |
| IL (1) | IL119412A (es) |
| RU (1) | RU2174407C2 (es) |
| TR (1) | TR199600852A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100706469B1 (ko) * | 1997-06-25 | 2007-04-10 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | 이황화결합으로 연결된 당단백질 호르몬 유사체, 이의제조방법 및 이의 용도 |
| ZA987497B (en) * | 1997-09-08 | 1999-02-23 | Akzo Nobel Nv | Expression of gonadotropins in dictyostelium |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3852422A (en) * | 1971-06-26 | 1974-12-03 | Serono Ist Farm | Long-active gonadotropins |
-
1995
- 1995-11-09 US US08/556,114 patent/US5691455A/en not_active Expired - Lifetime
-
1996
- 1996-10-11 IL IL11941296A patent/IL119412A/xx not_active IP Right Cessation
- 1996-10-22 DK DK96202940T patent/DK0785215T3/da active
- 1996-10-22 EP EP96202940A patent/EP0785215B1/en not_active Expired - Lifetime
- 1996-10-22 CA CA002188508A patent/CA2188508C/en not_active Expired - Fee Related
- 1996-10-22 HU HU9602923A patent/HU222043B1/hu not_active IP Right Cessation
- 1996-10-22 ES ES96202940T patent/ES2177721T3/es not_active Expired - Lifetime
- 1996-10-22 DE DE69621577T patent/DE69621577T2/de not_active Expired - Lifetime
- 1996-10-22 AT AT96202940T patent/ATE218584T1/de not_active IP Right Cessation
- 1996-10-23 CN CNB961219521A patent/CN1161381C/zh not_active Expired - Fee Related
- 1996-10-23 KR KR1019960047613A patent/KR100498532B1/ko not_active Expired - Fee Related
- 1996-10-23 RU RU96121076/14A patent/RU2174407C2/ru not_active IP Right Cessation
- 1996-10-23 BR BRPI9605220-1A patent/BR9605220B1/pt not_active IP Right Cessation
- 1996-10-24 JP JP28263896A patent/JP4086922B2/ja not_active Expired - Fee Related
- 1996-10-24 AU AU70378/96A patent/AU711081B2/en not_active Ceased
- 1996-10-24 AR ARP960104879A patent/AR004088A1/es active IP Right Grant
- 1996-10-24 TR TR96/00852A patent/TR199600852A2/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE218584T1 (de) | 2002-06-15 |
| HU9602923D0 (en) | 1996-12-30 |
| MX9605048A (es) | 1997-09-30 |
| HUP9602923A1 (hu) | 1999-02-01 |
| AU711081B2 (en) | 1999-10-07 |
| EP0785215B1 (en) | 2002-06-05 |
| IL119412A (en) | 2000-07-26 |
| JP4086922B2 (ja) | 2008-05-14 |
| CA2188508C (en) | 2005-12-20 |
| KR970021096A (ko) | 1997-05-28 |
| HU222043B1 (hu) | 2003-04-28 |
| ES2177721T3 (es) | 2002-12-16 |
| RU2174407C2 (ru) | 2001-10-10 |
| TR199600852A3 (es) | 1997-05-21 |
| DE69621577D1 (de) | 2002-07-11 |
| CN1161381C (zh) | 2004-08-11 |
| TR199600852A2 (tr) | 1997-05-21 |
| US5691455A (en) | 1997-11-25 |
| BR9605220A (pt) | 1998-07-21 |
| CA2188508A1 (en) | 1997-04-25 |
| BR9605220B1 (pt) | 2010-10-19 |
| CN1154371A (zh) | 1997-07-16 |
| DK0785215T3 (da) | 2002-09-16 |
| EP0785215A1 (en) | 1997-07-23 |
| JPH09176039A (ja) | 1997-07-08 |
| DE69621577T2 (de) | 2003-01-16 |
| IL119412A0 (en) | 1997-01-10 |
| AU7037896A (en) | 1997-05-01 |
| KR100498532B1 (ko) | 2005-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |