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AP720A - Hypolipidemic 1,4-benzothiazepine-1, 1-dioxides. - Google Patents

Hypolipidemic 1,4-benzothiazepine-1, 1-dioxides. Download PDF

Info

Publication number
AP720A
AP720A APAP/P/1997/000920A AP9700920A AP720A AP 720 A AP720 A AP 720A AP 9700920 A AP9700920 A AP 9700920A AP 720 A AP720 A AP 720A
Authority
AP
ARIPO
Prior art keywords
dioxide
tetrahydro
phenyl
ethyl
butyl
Prior art date
Application number
APAP/P/1997/000920A
Other languages
English (en)
Other versions
AP9700920A0 (en
Inventor
Lawrence Edward Brieaddy
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of AP9700920A0 publication Critical patent/AP9700920A0/xx
Application granted granted Critical
Publication of AP720A publication Critical patent/AP720A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
APAP/P/1997/000920A 1994-08-10 1995-08-09 Hypolipidemic 1,4-benzothiazepine-1, 1-dioxides. AP720A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28852794A 1994-08-10 1994-08-10
PCT/GB1995/001884 WO1996005188A1 (fr) 1994-08-10 1995-08-09 1,4-benzothiazepine-1,1-dioxydes a action hypolipidemique

Publications (2)

Publication Number Publication Date
AP9700920A0 AP9700920A0 (en) 1997-01-31
AP720A true AP720A (en) 1999-01-08

Family

ID=23107516

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/000920A AP720A (en) 1994-08-10 1995-08-09 Hypolipidemic 1,4-benzothiazepine-1, 1-dioxides.

Country Status (30)

Country Link
US (1) US5910494A (fr)
EP (2) EP1203769A1 (fr)
JP (1) JP2935756B2 (fr)
KR (1) KR100354288B1 (fr)
CN (1) CN1059673C (fr)
AP (1) AP720A (fr)
AT (1) ATE226946T1 (fr)
AU (1) AU696073B2 (fr)
BG (1) BG62048B1 (fr)
BR (1) BR9508586A (fr)
CA (1) CA2197099A1 (fr)
CZ (1) CZ37397A3 (fr)
DE (1) DE69528704T2 (fr)
DK (1) DK0775126T3 (fr)
EE (1) EE9700028A (fr)
ES (1) ES2185711T3 (fr)
FI (1) FI970531L (fr)
HU (1) HUT77129A (fr)
IL (1) IL114877A (fr)
IS (1) IS4418A (fr)
MX (1) MX9700890A (fr)
NO (1) NO308131B1 (fr)
NZ (1) NZ290911A (fr)
OA (1) OA10597A (fr)
PL (1) PL184512B1 (fr)
PT (1) PT775126E (fr)
RU (1) RU2156245C2 (fr)
SK (1) SK17797A3 (fr)
WO (1) WO1996005188A1 (fr)
ZA (1) ZA956647B (fr)

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PT775126E (pt) 2003-02-28
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