[go: up one dir, main page]

AP2707A - Antiviral drugs for treatment of arenavirus infection - Google Patents

Antiviral drugs for treatment of arenavirus infection

Info

Publication number
AP2707A
AP2707A AP2010005172A AP2010005172A AP2707A AP 2707 A AP2707 A AP 2707A AP 2010005172 A AP2010005172 A AP 2010005172A AP 2010005172 A AP2010005172 A AP 2010005172A AP 2707 A AP2707 A AP 2707A
Authority
AP
ARIPO
Prior art keywords
treatment
antiviral drugs
arenavirus infection
arenavirus
infection
Prior art date
Application number
AP2010005172A
Other languages
English (en)
Other versions
AP2010005172A0 (en
Inventor
Dongcheng Dai
Dennis E Hruby
Tovc C Bolken
Original Assignee
Siga Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Technologies Inc filed Critical Siga Technologies Inc
Publication of AP2010005172A0 publication Critical patent/AP2010005172A0/en
Application granted granted Critical
Publication of AP2707A publication Critical patent/AP2707A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AP2010005172A 2007-08-27 2008-08-26 Antiviral drugs for treatment of arenavirus infection AP2707A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93569107P 2007-08-27 2007-08-27
PCT/US2008/074328 WO2009029622A2 (en) 2007-08-27 2008-08-26 Antiviral drugs for treatment of arenavirus infection

Publications (2)

Publication Number Publication Date
AP2010005172A0 AP2010005172A0 (en) 2010-02-28
AP2707A true AP2707A (en) 2013-07-29

Family

ID=40388109

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2010005172A AP2707A (en) 2007-08-27 2008-08-26 Antiviral drugs for treatment of arenavirus infection

Country Status (12)

Country Link
US (3) US8461177B2 (xx)
EP (1) EP2182805B1 (xx)
JP (1) JP5393679B2 (xx)
KR (1) KR101585584B1 (xx)
CN (1) CN101801189B (xx)
AP (1) AP2707A (xx)
AU (1) AU2008293532B2 (xx)
CA (1) CA2698075C (xx)
ES (1) ES2424214T3 (xx)
MX (1) MX2010002278A (xx)
WO (1) WO2009029622A2 (xx)
ZA (1) ZA201001389B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2590962A1 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
JP2009525338A (ja) 2006-02-01 2009-07-09 サイガ・テクノロジーズ・インコーポレーテッド 抗アレナウイルス化合物
US8791110B2 (en) 2006-02-01 2014-07-29 Siga Technologies, Inc. Anti-arenaviral compounds
US8871746B2 (en) 2006-03-02 2014-10-28 Kineta Four, LLC Antiviral drugs for treatment of arenavirus infection
EP1988776B1 (en) 2006-03-02 2012-08-08 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
AU2008256727A1 (en) 2007-05-23 2008-12-04 Siga Technologies, Inc. Antiviral drugs for treatment or prevention of dengue infection
KR101585584B1 (ko) 2007-08-27 2016-01-14 키네타 포 엘엘씨 아레나바이러스 감염을 치료하기 위한 항바이러스 약물
BR112014020345B1 (pt) 2012-02-17 2021-09-21 Kineta Four Llc Composto antiviral, composição farmacêutica compreendendo dito composto e uso dos mesmos para tratar infecção viral ou doença associada à mesma
EP3065778A1 (en) * 2013-11-06 2016-09-14 Celgene Corporation Compositions and methods for the treatment of viral diseases with pde4 modulators
MX391006B (es) 2014-09-22 2025-03-21 Univ Minnesota Sistema de genética inversa del virus pichindé y métodos de uso.
US11352328B2 (en) 2016-07-12 2022-06-07 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus
IL282021B2 (en) 2018-10-05 2025-04-01 Annapurna Bio Inc Compounds and compositions for treating conditions associated with APJ receptor activity
US12419865B2 (en) 2018-12-06 2025-09-23 Arisan Therapeutics Inc. Compounds for the treatment of arenavirus infection
CN111973598B (zh) * 2020-09-09 2021-04-13 武汉珈创生物技术股份有限公司 达拉非尼和/或其可药用衍生物在制备抗沙粒病毒药物中的应用
EP4367112A1 (en) 2021-07-09 2024-05-15 Plexium, Inc. Aryl compounds and pharmaceutical compositions that modulate ikzf2
WO2023107705A1 (en) 2021-12-10 2023-06-15 Incyte Corporation Bicyclic amines as cdk12 inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855713B2 (en) * 2001-09-08 2005-02-15 Boehringer Ingelheim Pharma Kg Benzimidazole derivatives, a process for their manufacture and use as a medicine
US20060194969A1 (en) * 2002-12-13 2006-08-31 Zimmermann Peter J 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS527965A (en) * 1975-06-05 1977-01-21 Icn Pharmaceuticals 33deazaguanine derivatives and antiiviral and antiibacterial agent containing same
US4131735A (en) 1975-11-25 1978-12-26 Agfa-Gevaert, N.V. Preparation of α-acylacetamides using tetramethyl guanidine condensing agent
US4492708A (en) 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
CA2338147A1 (en) * 1998-07-20 2000-02-03 Kuo-Long Yu Substituted benzimidazole antiviral agents
AU7922900A (en) * 1999-10-27 2001-05-08 Novartis Ag Thiazole and imidazo (4,5-b) pyridine compounds and their pharmaceutical use
HN2001000224A (es) * 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
US7687641B2 (en) 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
KR20100018029A (ko) 2004-07-18 2010-02-16 씨에스엘 리미티드 면역자극 복합체 및 향상된 인터페론-감마 반응을 유도하기 위한 올리고뉴클레오티드 제제
CA2590962A1 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
JP2009525338A (ja) 2006-02-01 2009-07-09 サイガ・テクノロジーズ・インコーポレーテッド 抗アレナウイルス化合物
WO2007100888A2 (en) 2006-03-02 2007-09-07 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
EP1988776B1 (en) 2006-03-02 2012-08-08 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
MX363189B (es) 2007-04-23 2019-03-14 Siga Tech Inc Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas.
AU2008256727A1 (en) 2007-05-23 2008-12-04 Siga Technologies, Inc. Antiviral drugs for treatment or prevention of dengue infection
KR101585584B1 (ko) 2007-08-27 2016-01-14 키네타 포 엘엘씨 아레나바이러스 감염을 치료하기 위한 항바이러스 약물
CA2709784A1 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
BRPI0905388A2 (pt) 2008-01-15 2015-10-13 Siga Technologies Inc "composição farmacêutica; compostos e métodos de tratamento de infecção por arenavirus"
EP2293671A4 (en) 2008-06-03 2012-03-21 Siga Technologies Inc SMALL MOLECULAR INHIBITORS FOR TREATING OR PREVENTING DENGUE INFECTIONS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855713B2 (en) * 2001-09-08 2005-02-15 Boehringer Ingelheim Pharma Kg Benzimidazole derivatives, a process for their manufacture and use as a medicine
US20060194969A1 (en) * 2002-12-13 2006-08-31 Zimmermann Peter J 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KATRITZKY, A. R. ET AL: "The preparation of indolocarbazoles. VI. Compounds from two of the amino-1-phenylbenzotriazoles", XP002609242, retrieved from STN Database accession no. 1954:21836 & JOURNAL OF THE CHEMICAL SOCIETY 412-16 CODEN: JCSOA9; ISSN: 0368-1769, 1953, *
MILATA V ET AL: "Benzazolylmethylheteroarylamines", COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, INSTITUTE OF ORGANIC CHEMISTRY & BIOCHEMISTRY, PRAGUE; CZ, vol. 59, no. 3, 1 January 1994 (1994-01-01), pages 725-730, XP002592059, ISSN: 0010-0765 *

Also Published As

Publication number Publication date
JP5393679B2 (ja) 2014-01-22
ZA201001389B (en) 2010-11-24
WO2009029622A3 (en) 2009-04-23
JP2010538000A (ja) 2010-12-09
CA2698075C (en) 2016-04-12
CN101801189B (zh) 2015-08-26
WO2009029622A2 (en) 2009-03-05
CN101801189A (zh) 2010-08-11
EP2182805A2 (en) 2010-05-12
CA2698075A1 (en) 2009-03-05
AU2008293532B2 (en) 2014-08-28
AP2010005172A0 (en) 2010-02-28
EP2182805B1 (en) 2013-06-26
US9096597B2 (en) 2015-08-04
US20110064693A1 (en) 2011-03-17
MX2010002278A (es) 2010-03-17
AU2008293532A1 (en) 2009-03-05
KR101585584B1 (ko) 2016-01-14
ES2424214T3 (es) 2013-09-30
KR20100080516A (ko) 2010-07-08
US20140128426A1 (en) 2014-05-08
EP2182805A4 (en) 2010-12-22
US20140243367A1 (en) 2014-08-28
US8754082B2 (en) 2014-06-17
US8461177B2 (en) 2013-06-11

Similar Documents

Publication Publication Date Title
AP2707A (en) Antiviral drugs for treatment of arenavirus infection
ZA200807507B (en) Antiviral drugs for treatment of arenavirus infection
ZA201004193B (en) Antiviral drugs for treatment of arenavirus infection
ZA201007617B (en) Antiviral drugs for treatment of arenavirus infection
ZA200807506B (en) Antiviral drugs for treatment of arenavirus infection
AP2009005070A0 (en) Antiviral drugs for treatment or prevention of dengue infection
IL251327A0 (en) Antiviral compounds, preparations containing them and their use for the treatment of arnovirus infections
SI2073860T1 (sl) Obloge, ki sproĺ äśajo zdravilo za medicinske naprave
ZA200906126B (en) Use of IL-23 antigonists for treatment of infection
PL2154969T3 (pl) Leczenie synukleinopatii
NO2016023I1 (no) Glycerol fenylbutyrat
HRP20181877T1 (hr) Postupci za liječenje lijekovima koji uklanjaju amonijak
GB0715790D0 (en) Drug combination for the treatment of sialorrhoea
EP2359835A4 (en) THERAPEUTIC AGAINST VIRUS INFECTIONS WITH POLYALKYLENEIMIN
AP2008004560A0 (en) Treatment of HIV
GB0815179D0 (en) Medication and treatment for infection
GB0720136D0 (en) Treatment of blood disorded
IL186961A0 (en) Inhalation device for simultaneous treatment of multiple patients
SI2330892T1 (sl) Postopki zdravljenja z uporabo zdravil, ki odstranjujejo amoniak
GB0813716D0 (en) Treatment of viral infection
GB0704989D0 (en) Treatment of influenza
GB0700886D0 (en) Medical treatment