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NO993731L - Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne - Google Patents

Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne

Info

Publication number
NO993731L
NO993731L NO993731A NO993731A NO993731L NO 993731 L NO993731 L NO 993731L NO 993731 A NO993731 A NO 993731A NO 993731 A NO993731 A NO 993731A NO 993731 L NO993731 L NO 993731L
Authority
NO
Norway
Prior art keywords
medicine
pyrrolopyrazolopyrimidine
compound
pyrrolopyrazolopyrimidine compound
Prior art date
Application number
NO993731A
Other languages
English (en)
Other versions
NO314404B1 (no
NO993731D0 (no
Inventor
Takayuki Namiki
Masayuki Yuasa
Takako Takakuwa
Satoshi Ichinomiya
Yukio Kawazu
Kenichi Kishii
Norio Funayama
Mariko Harada
Kyoko Taneda
Naoki Hiyama
Tomoaki Yahiro
Mayumi Sugio
Masashi Tamai
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Publication of NO993731D0 publication Critical patent/NO993731D0/no
Publication of NO993731L publication Critical patent/NO993731L/no
Publication of NO314404B1 publication Critical patent/NO314404B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19993731A 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav NO314404B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9020387A JPH10218881A (ja) 1997-02-03 1997-02-03 新規なピロロピラゾロピリミジン誘導体
PCT/JP1998/000315 WO1998033799A1 (en) 1997-02-03 1998-01-27 Pyrrolopyrazolopyrimidine compound and medicine comprising the same

Publications (3)

Publication Number Publication Date
NO993731D0 NO993731D0 (no) 1999-08-02
NO993731L true NO993731L (no) 1999-09-22
NO314404B1 NO314404B1 (no) 2003-03-17

Family

ID=12025624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993731A NO314404B1 (no) 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav

Country Status (7)

Country Link
US (2) US5942515A (no)
EP (1) EP1021447A1 (no)
JP (1) JPH10218881A (no)
AU (1) AU725356B2 (no)
CA (1) CA2228360A1 (no)
NO (1) NO314404B1 (no)
WO (1) WO1998033799A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE271051T1 (de) * 1997-02-14 2004-07-15 Pola Chem Ind Inc Heilmittel/vorbeugemittel für erkrankungen der atemwege
US6329382B1 (en) 1997-02-14 2001-12-11 Pola Chemical Industries, Inc. Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidine remedies/preventives for respiratory diseases
TWI271406B (en) * 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
DE10012861C2 (de) * 2000-03-16 2002-07-11 Gsf Forschungszentrum Umwelt Rekombinante HHV8-DNA
ATE493988T1 (de) 2001-07-13 2011-01-15 Btg Internat Ltd Company No 2664412 Pyrimidinderivate enthaltendes medikament
US7329668B2 (en) 2003-02-25 2008-02-12 Bristol-Myers Squibb Company Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
CN101115754B (zh) * 2005-02-16 2010-11-10 巴斯福股份公司 5-烷氧基烷基-6-烷基-7-氨基唑并嘧啶、其制备方法、其在防治病原性真菌中的用途以及包含所述物质的试剂
SI2266990T1 (sl) 2008-04-15 2013-01-31 Eisai R&D Management Co. Ltd. Spojina 3-fenilpirazolo(5,1-b)tiazola
WO2012024495A1 (en) * 2010-08-18 2012-02-23 Massachusetts Institute Of Technology Use of azides in synthesis
WO2012027239A1 (en) * 2010-08-23 2012-03-01 Schering Corporation NOVEL PYRAZOLO[1,5-a]PYRROLO[3,2-e]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
WO2012178125A1 (en) 2011-06-22 2012-12-27 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
SMT202100425T1 (it) 2012-12-07 2021-09-14 Vertex Pharma 2-ammino-n-(piperidin-1-il-piridin-3-il) pirazolo[1,5alpha]piirimidina-3-carbossiammide come inibitore di atr chinasi
US8969360B2 (en) 2013-03-15 2015-03-03 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
WO2014143240A1 (en) 2013-03-15 2014-09-18 Vertex Pharmaceuticals Incorporated Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase
EP2970289A1 (en) 2013-03-15 2016-01-20 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
PT3077397T (pt) 2013-12-06 2020-01-22 Vertex Pharma Composto de 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]pirazolo[1,5-a]pirimidin-3-carboxamida útil como inibidor da atr quinase, a sua preparação, diferentes formas sólidas e derivados radiomarcados do mesmo
SI3152212T1 (sl) 2014-06-05 2020-06-30 Vertex Pharmaceuticals Inc. Radioaktivno označeni derivati 2-amino-6-fluoro-N-(5-fluoro-piridin-3-IL)-pirazolo (1,5-A)pirimidin-3- karboksamidne spojine, koristni kot inhibitor kinaze ATR, priprava navedene spojine in njene različne trdne oblike
SG10201811175WA (en) 2014-06-17 2019-01-30 Vertex Pharma Method for treating cancer using a combination of chk1 and atr inhibitors
HK1258570A1 (zh) 2015-09-30 2019-11-15 Vertex Pharmaceuticals Inc. 使用dna损伤剂及atr抑制剂的组合治疗癌症的方法
CN116265467B (zh) * 2021-12-16 2025-04-18 成都科岭源医药技术有限公司 一种合成tyk2抑制剂的中间体及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276880A (ja) * 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
DK69592A (da) * 1992-05-26 1993-11-27 Eskofot As Apparat til eksponering og fremkaldelse af lysfoelsomt materiale, fortrinsvis offsetplader

Also Published As

Publication number Publication date
AU725356B2 (en) 2000-10-12
WO1998033799A1 (en) 1998-08-06
NO314404B1 (no) 2003-03-17
AU5577798A (en) 1998-08-25
JPH10218881A (ja) 1998-08-18
EP1021447A1 (en) 2000-07-26
US5942515A (en) 1999-08-24
NO993731D0 (no) 1999-08-02
CA2228360A1 (en) 1998-08-03
US6057330A (en) 2000-05-02

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