NO995531D0 - Nye mellomprodukter og fremgangsmåte for fremstilling derav - Google Patents
Nye mellomprodukter og fremgangsmåte for fremstilling deravInfo
- Publication number
- NO995531D0 NO995531D0 NO995531A NO995531A NO995531D0 NO 995531 D0 NO995531 D0 NO 995531D0 NO 995531 A NO995531 A NO 995531A NO 995531 A NO995531 A NO 995531A NO 995531 D0 NO995531 D0 NO 995531D0
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- processes
- new intermediates
- thienyl
- general formula
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- HVLUYXIJZLDNIS-UHFFFAOYSA-N 2-thiophen-2-ylethanamine Chemical compound NCCC1=CC=CS1 HVLUYXIJZLDNIS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9700886A HU225504B1 (en) | 1997-05-13 | 1997-05-13 | Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them |
| PCT/HU1998/000046 WO1998051682A1 (en) | 1997-05-13 | 1998-05-11 | New intermediates and process for the preparation thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO995531D0 true NO995531D0 (no) | 1999-11-12 |
| NO995531L NO995531L (no) | 1999-12-13 |
| NO325305B1 NO325305B1 (no) | 2008-03-25 |
Family
ID=89995121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19995531A NO325305B1 (no) | 1997-05-13 | 1999-11-12 | Nye mellomprodukter, isomerer derav og fremgangsmate for fremstilling av disse |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6215005B1 (no) |
| EP (1) | EP0981525B1 (no) |
| JP (1) | JP4279903B2 (no) |
| AT (1) | ATE258551T1 (no) |
| AU (1) | AU7444698A (no) |
| BR (1) | BR9809113B1 (no) |
| CA (1) | CA2288637C (no) |
| DE (1) | DE69821347T2 (no) |
| DK (1) | DK0981525T3 (no) |
| ES (1) | ES2213900T3 (no) |
| HU (1) | HU225504B1 (no) |
| NO (1) | NO325305B1 (no) |
| PT (1) | PT981525E (no) |
| WO (1) | WO1998051682A1 (no) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU226421B1 (en) | 1998-11-09 | 2008-12-29 | Sanofi Aventis | Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides |
| US6495691B1 (en) | 2001-07-06 | 2002-12-17 | Brantford Chemicals Inc. | Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives |
| US6767913B2 (en) | 2001-12-18 | 2004-07-27 | Teva Pharmaceutical Industries Ltd. | Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms |
| US7074928B2 (en) | 2002-01-11 | 2006-07-11 | Teva Pharmaceutical Industries, Ltd. | Polymorphs of clopidogrel hydrogensulfate |
| HUP0200438A3 (en) * | 2002-02-06 | 2003-10-28 | Egis Gyogyszergyar Nyilvanosan | Novel clopidogrel hydrochloride polymorphs, process for the preparation thereof, their use and pharmaceutical compositions containing them |
| IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| US6800759B2 (en) * | 2002-08-02 | 2004-10-05 | Teva Pharmaceutical Industries Ltd. | Racemization and enantiomer separation of clopidogrel |
| AU2003238664A1 (en) | 2003-03-12 | 2004-09-30 | Cadila Healthcare Limited | Polymorphs and amorphous form of (s) - (+) -clopidogrel bisulfate |
| US20040250673A1 (en) * | 2003-06-10 | 2004-12-16 | Salerno Paul Michael | Ergonomic pedal board |
| GB0321256D0 (en) | 2003-09-11 | 2003-10-08 | Generics Uk Ltd | Novel crystalline compounds |
| DE602004025267D1 (de) | 2003-11-03 | 2010-03-11 | Cadila Healthcare Ltd | Verfahren zur herstellung form i von (s)-(+)- clopidogrelbisulfat |
| US20060154957A1 (en) * | 2004-09-21 | 2006-07-13 | Nina Finkelstein | Crystalline clopidogrel hydrobromide and processes for preparation thereof |
| JP2008526896A (ja) * | 2005-02-24 | 2008-07-24 | テバ ファーマシューティカル インダストリーズ リミティド | 医薬製剤に適したグロピドグレル塩基及びその調製 |
| WO2007032023A2 (en) | 2005-07-12 | 2007-03-22 | Rpg Life Sciences Limited | A process for preparation of methyl-(+)-(s)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h)-acetic acid methyl ester or salts thereof having higher chiral purity and products thereof |
| US20090099363A1 (en) * | 2006-04-27 | 2009-04-16 | Saxena Rahul | Process for the preparation of polymorphic forms of clopidogrel hydrogen sulfate |
| CA2655844A1 (en) * | 2006-08-03 | 2008-02-14 | Teva Pharmaceutical Industries Ltd. | Process for preparing clopidogrel bisulphate |
| EP1980563A1 (en) | 2007-04-09 | 2008-10-15 | BATTULA, Srinivasa Reddy | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate |
| WO2010046476A1 (en) * | 2008-10-24 | 2010-04-29 | Sandoz Ag | A process for the preparation of s-clopidogrel |
| KR102860417B1 (ko) * | 2023-08-21 | 2025-09-17 | ㈜분자와물질 | 다성분, 단일반응에 의한 질소-치환된 아미노산을 포함하는 테트라하이드로티에노피리딘 유도체의 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2508455A1 (fr) | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines |
| FR2530247B1 (fr) | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
| FR2608607B1 (fr) | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
| FR2623810B2 (fr) | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| FR2614619B1 (fr) | 1987-04-29 | 1989-09-15 | Sanofi Sa | Procede de preparation de n-((chloro-2)-benzyl) (thienyl-2)-2 ethylamine |
| FR2652575B1 (fr) * | 1989-09-29 | 1992-01-24 | Sanofi Sa | Procede de preparation d'acides alpha-bromo phenylacetiques. |
| FR2664596B1 (fr) * | 1990-07-10 | 1994-06-10 | Sanofi Sa | Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese. |
| WO1998011064A1 (en) * | 1996-09-12 | 1998-03-19 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2-substituted ethyl-2-amines |
-
1997
- 1997-05-13 HU HU9700886A patent/HU225504B1/hu unknown
-
1998
- 1998-05-11 AU AU74446/98A patent/AU7444698A/en not_active Abandoned
- 1998-05-11 CA CA002288637A patent/CA2288637C/en not_active Expired - Lifetime
- 1998-05-11 EP EP98921668A patent/EP0981525B1/en not_active Expired - Lifetime
- 1998-05-11 DE DE69821347T patent/DE69821347T2/de not_active Expired - Lifetime
- 1998-05-11 BR BRPI9809113-1A patent/BR9809113B1/pt not_active IP Right Cessation
- 1998-05-11 AT AT98921668T patent/ATE258551T1/de active
- 1998-05-11 ES ES98921668T patent/ES2213900T3/es not_active Expired - Lifetime
- 1998-05-11 WO PCT/HU1998/000046 patent/WO1998051682A1/en not_active Ceased
- 1998-05-11 JP JP54895498A patent/JP4279903B2/ja not_active Expired - Lifetime
- 1998-05-11 PT PT98921668T patent/PT981525E/pt unknown
- 1998-05-11 US US09/423,548 patent/US6215005B1/en not_active Expired - Lifetime
- 1998-05-11 DK DK98921668T patent/DK0981525T3/da active
-
1999
- 1999-11-12 NO NO19995531A patent/NO325305B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE258551T1 (de) | 2004-02-15 |
| HUP9700886A3 (en) | 2000-06-28 |
| BR9809113B1 (pt) | 2010-03-09 |
| HU9700886D0 (en) | 1997-07-28 |
| JP4279903B2 (ja) | 2009-06-17 |
| US6215005B1 (en) | 2001-04-10 |
| HUP9700886A2 (hu) | 1999-09-28 |
| NO325305B1 (no) | 2008-03-25 |
| HU225504B1 (en) | 2007-01-29 |
| CA2288637C (en) | 2005-11-15 |
| EP0981525B1 (en) | 2004-01-28 |
| DE69821347D1 (de) | 2004-03-04 |
| CA2288637A1 (en) | 1998-11-19 |
| JP2001525817A (ja) | 2001-12-11 |
| ES2213900T3 (es) | 2004-09-01 |
| BR9809113A (pt) | 2000-08-01 |
| PT981525E (pt) | 2004-05-31 |
| DE69821347T2 (de) | 2004-12-02 |
| DK0981525T3 (da) | 2004-05-10 |
| NO995531L (no) | 1999-12-13 |
| EP0981525A1 (en) | 2000-03-01 |
| AU7444698A (en) | 1998-12-08 |
| WO1998051682A1 (en) | 1998-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |