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NO982315L - FremgangsmÕte for fremstilling av 3-amino-1,2,4-benzotriazindioksyd - Google Patents

FremgangsmÕte for fremstilling av 3-amino-1,2,4-benzotriazindioksyd

Info

Publication number
NO982315L
NO982315L NO982315A NO982315A NO982315L NO 982315 L NO982315 L NO 982315L NO 982315 A NO982315 A NO 982315A NO 982315 A NO982315 A NO 982315A NO 982315 L NO982315 L NO 982315L
Authority
NO
Norway
Prior art keywords
amino
preparation
benzofurazan
oxide
benzotriazine
Prior art date
Application number
NO982315A
Other languages
English (en)
Other versions
NO311216B1 (no
NO982315D0 (no
Inventor
Richard E Philion
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO982315D0 publication Critical patent/NO982315D0/no
Publication of NO982315L publication Critical patent/NO982315L/no
Publication of NO311216B1 publication Critical patent/NO311216B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
    • C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO19982315A 1995-12-04 1998-05-20 Fremgangsmåte for fremstilling av 3-amino-1,2,4- benzotriazindioksyd NO311216B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/566,979 US5672702A (en) 1995-12-04 1995-12-04 Process for preparing 3 amino 1, 2, 4-benzotriazine dioxide
PCT/US1996/018761 WO1997020828A1 (en) 1995-12-04 1996-11-21 Process for preparing 3-amino-1,2,4-benzotriazine dioxide

Publications (3)

Publication Number Publication Date
NO982315D0 NO982315D0 (no) 1998-05-20
NO982315L true NO982315L (no) 1998-05-20
NO311216B1 NO311216B1 (no) 2001-10-29

Family

ID=24265255

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19982315A NO311216B1 (no) 1995-12-04 1998-05-20 Fremgangsmåte for fremstilling av 3-amino-1,2,4- benzotriazindioksyd

Country Status (18)

Country Link
US (1) US5672702A (no)
EP (1) EP0865435B1 (no)
JP (1) JP2000501705A (no)
KR (1) KR100502041B1 (no)
CN (1) CN1068595C (no)
AT (1) ATE213234T1 (no)
AU (1) AU721627B2 (no)
BR (1) BR9611864A (no)
CZ (1) CZ292732B6 (no)
DE (1) DE69619267T2 (no)
DK (1) DK0865435T3 (no)
ES (1) ES2172696T3 (no)
MX (1) MX9804421A (no)
NO (1) NO311216B1 (no)
NZ (1) NZ323602A (no)
PT (1) PT865435E (no)
RU (1) RU2178413C2 (no)
WO (1) WO1997020828A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042192A1 (en) * 2001-11-13 2003-05-22 Sanofi-Synthelabo Preparation of 3-amino-1,2,4-benzotriazine dioxide
EP1931769A2 (en) * 2005-10-03 2008-06-18 Genetix Pharmaceuticals Inc. Method for selectively depleting hypoxic cells
CN101683319B (zh) * 2008-09-24 2012-09-05 杭州民生药业有限公司 一种替拉扎明非肠道给药含水制剂及其制备方法
JP2015500295A (ja) * 2011-12-07 2015-01-05 エスアールアイ インターナショナルＳＲＩ Ｉｎｔｅｒｎａｔｉｏｎａｌ ヒト結核菌を標的とする医薬としてのベンゾトリアジンオキサイド類
US9278124B2 (en) 2012-10-16 2016-03-08 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794742A (fr) * 1972-02-01 1973-07-30 Bayer Ag Nouveaux di-n-oxydes (1,4) de benzo-1,2,4-triazine, leur procede de preparation et leur application comme medicaments et additifs de nutrition
US3980779A (en) * 1972-02-01 1976-09-14 Bayer Aktiengesellschaft 3-Amino-1,2,4-benzotriazine-1,4-di-N-oxide compositions and method of using same
US3991189A (en) * 1972-11-15 1976-11-09 Bayer Aktiengesellschaft Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives
DE2255946A1 (de) * 1972-11-15 1974-05-22 Bayer Ag Verfahren zur herstellung von neuen eckige klammer auf 3-benzo-1,2,4-triazinyldioxid (1,4) eckige klammer zu -harnstoffen, sowie ihre verwendung als arzneimittel und futterzusatzmittel
US3957779A (en) * 1972-11-15 1976-05-18 Bayer Aktiengesellschaft Benzo-1,2,4-triazines
DE2255947A1 (de) * 1972-11-15 1974-05-22 Bayer Ag Substituierte 3-amino-benzo-1,2,4triazin-di-n-oxide (1,4), verfahren zu ihrer herstellung sowie ihre verwendung als antimikrobielle mittel
CH576231A5 (en) * 1973-02-02 1976-06-15 Ciba Geigy Ag 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth
WO1988002366A1 (en) * 1986-09-25 1988-04-07 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
US5175287A (en) * 1986-09-25 1992-12-29 S R I International Process for preparing 1,2,4-benzotriazine oxides
HU221201B1 (en) * 1989-09-18 2002-08-28 Stanford Res Inst Int Process for producing 1,2,4-benzotriazin-oxide derivatives applicable as radiation sensitizer and selective cytotoxic agent, and pharmaceutical compositions containing them
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin

Also Published As

Publication number Publication date
NO311216B1 (no) 2001-10-29
BR9611864A (pt) 1999-05-18
ATE213234T1 (de) 2002-02-15
EP0865435A1 (en) 1998-09-23
KR19990071913A (ko) 1999-09-27
CN1207736A (zh) 1999-02-10
PT865435E (pt) 2002-07-31
NO982315D0 (no) 1998-05-20
NZ323602A (en) 1999-10-28
KR100502041B1 (ko) 2005-09-26
AU1058897A (en) 1997-06-27
EP0865435A4 (en) 1998-12-23
MX9804421A (es) 1998-09-30
CZ172398A3 (cs) 1998-09-16
CN1068595C (zh) 2001-07-18
RU2178413C2 (ru) 2002-01-20
CZ292732B6 (cs) 2003-12-17
EP0865435B1 (en) 2002-02-13
JP2000501705A (ja) 2000-02-15
US5672702A (en) 1997-09-30
AU721627B2 (en) 2000-07-13
ES2172696T3 (es) 2002-10-01
HK1017358A1 (en) 1999-11-19
DK0865435T3 (da) 2002-05-27
DE69619267T2 (de) 2003-12-24
WO1997020828A1 (en) 1997-06-12
DE69619267D1 (de) 2002-03-21

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