NO982124L - Kondenserte imidazolderivater som multilegemiddel resistanse modulatorer - Google Patents

Kondenserte imidazolderivater som multilegemiddel resistanse modulatorer

Info

Publication number: NO982124L
Authority: NO; Norway
Prior art keywords: multidrug resistance; imidazole derivatives; condensed imidazole; resistance modulators; modulators
Prior art date: 1996-03-19

Application number

NO982124A

Other languages

English (en)

Other versions

NO310659B1 (no

NO982124D0 (no

Inventor

Frans Eduard Janssens

Joseph Elisabeth Leenaerts

Fran Ois Maria Sommen

Dominique Louis Nest Surleraux

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-19

Filing date

1998-05-11

Publication date

1998-09-18

1998-05-11 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1998-05-11 Publication of NO982124D0 publication Critical patent/NO982124D0/no

1998-09-18 Publication of NO982124L publication Critical patent/NO982124L/no

2001-08-06 Publication of NO310659B1 publication Critical patent/NO310659B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

NO19982124A 1996-03-19 1998-05-11 Kondenserte imidazolderivater som multilegemiddel resistanse modulatorer NO310659B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96200755		1996-03-19
PCT/EP1997/001264 WO1997034897A1 (en)	1996-03-19	1997-03-11	Fused imidazole derivatives as multidrug resistance modulators

Publications (3)

Publication Number	Publication Date
NO982124D0 NO982124D0 (no)	1998-05-11
NO982124L true NO982124L (no)	1998-09-18
NO310659B1 NO310659B1 (no)	2001-08-06

Family

ID=8223797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19982124A NO310659B1 (no)	1996-03-19	1998-05-11	Kondenserte imidazolderivater som multilegemiddel resistanse modulatorer

Country Status (29)

Country	Link
US (3)	US6218381B1 (no)
EP (1)	EP0888352B1 (no)
JP (3)	JP3630434B2 (no)
KR (2)	KR100349500B1 (no)
CN (1)	CN1083453C (no)
AR (1)	AR006271A1 (no)
AT (1)	ATE241626T1 (no)
BG (1)	BG62734B1 (no)
BR (1)	BR9708140A (no)
CA (1)	CA2237594C (no)
CZ (1)	CZ294060B6 (no)
DE (1)	DE69722389T2 (no)
EA (1)	EA001004B1 (no)
EE (1)	EE03773B1 (no)
ES (1)	ES2200159T3 (no)
HR (1)	HRP970161B1 (no)
HU (1)	HU224528B1 (no)
ID (1)	ID16375A (no)
IL (1)	IL124572A (no)
MX (1)	MX9804426A (no)
MY (1)	MY118282A (no)
NO (1)	NO310659B1 (no)
NZ (1)	NZ330466A (no)
PL (1)	PL193444B1 (no)
SK (1)	SK284434B6 (no)
TR (1)	TR199801191T2 (no)
TW (1)	TW527186B (no)
WO (1)	WO1997034897A1 (no)
ZA (1)	ZA972351B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6544979B1 (en)	1997-09-18	2003-04-08	Janssen Pharmaceuticals, N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceutical agents
CA2326485C (en) *	1998-04-01	2008-12-09	Rtp Pharma Inc.	Anticancer compositions
US6743794B2 (en)	1999-12-22	2004-06-01	Eli Lilly And Company	Methods and compounds for inhibiting MRP1
US6376514B1 (en)	2000-10-17	2002-04-23	The Procter & Gamble Co.	Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en)	2000-10-17	2004-02-17	The Procter & Gamble Company	Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
ES2475240T3 (es)	2001-06-12	2014-07-10	Janssen Pharmaceutica Nv	Derivados de imidazol tetrac�clicos sustituidos novedosos, procesos para su preparación, composiciones farmacéuticas que los comprenden y su uso como medicamento
EP1832287B1 (en) *	2001-11-23	2009-02-25	Janssen Pharmaceutica, N.V.	The use of histamine receptor antagonists for the reduction of intracranial pressure
GB0301736D0 (en) *	2003-01-24	2003-02-26	Xenova Ltd	Pharmaceutical compounds
US9682984B2 (en) *	2013-03-25	2017-06-20	Crystal Pharma S.A.U.	Methods for the preparation of alcaftadine
CN103408549B (zh) *	2013-06-14	2016-01-20	苏州汇和药业有限公司	一种阿卡他定中间体的制备方法

Family Cites Families (24)

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Publication number	Priority date	Publication date	Assignee	Title
DE2418502C3 (de) *	1974-04-11	1980-04-24	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4153719A (en) *	1977-09-06	1979-05-08	Sterling Drug Inc.	Aromatic diketones
JPS56125326A (en) *	1980-03-07	1981-10-01	Asahi Kagaku Kogyo Kk	Preparation of chlorinated phenoxytoluenes in high selectivity
US4567184A (en)	1982-12-01	1986-01-28	Usv Pharmaceutical Corporation	Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
US4778931A (en)	1982-12-01	1988-10-18	Usv Pharmaceutical Corporation	Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
US4794188A (en)	1982-12-01	1988-12-27	Usv Pharmaceutical Corporation	Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
US4588722A (en)	1984-01-09	1986-05-13	Janssen Pharmaceutica N.V.	N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
JPS61151176A (ja) *	1984-12-24	1986-07-09	Sumitomo Chem Co Ltd	ベンズイミダゾール誘導体およびそれを有効成分とする殺虫、殺ダニ剤
US4631287A (en) *	1985-04-16	1986-12-23	Usv Pharmaceutical Corp.	Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
AU7100887A (en) *	1986-04-07	1987-10-08	Sumitomo Chemical Company, Limited	Halogenated aromatic ethers and alcohol and aldehyde intermediates
JPS6475441A (en) *	1987-09-16	1989-03-22	Sumitomo Chemical Co	Production of optically active ether compound
JPH01254680A (ja) *	1988-04-01	1989-10-11	Sumitomo Chem Co Ltd	複素環化合物、その製造法およびそれを有効成分とする殺菌剤
US5393753A (en) *	1990-10-10	1995-02-28	Schering Corporation	Substituted imidazobenzazepines
IL101851A (en)	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
IL101850A (en)	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
GB9122590D0 (en) *	1991-10-24	1991-12-04	Lilly Industries Ltd	Pharmaceutical compounds
ATE182582T1 (de) *	1992-02-06	1999-08-15	Merrell Pharma Inc	Umkehr der mehrfachresistenz gegen medikamente durch triphenyl-piperidin derivate
AU676702B2 (en)	1992-12-04	1997-03-20	Janssen Pharmaceutica N.V.	Antiallergic imidazo{1,2-a}(pyrrolo, thieno or furano){2,3-d}azepine derivatives
EP0691962B1 (en)	1993-03-29	2000-09-13	Basf Aktiengesellschaft	1-amino-3-phenoxy propane derivatives as modulators of multi-drug resistance
ATE198480T1 (de)	1993-07-13	2001-01-15	Janssen Pharmaceutica Nv	Antiallergische imidazoazepine
US5486612A (en) *	1993-12-14	1996-01-23	Eli Lilly And Company	N-benzyl dihydroindole LTD4 antagonists
US5596008A (en) *	1995-02-10	1997-01-21	G. D. Searle & Co.	3,4-Diaryl substituted pyridines for the treatment of inflammation
FR2731708B1 (fr)	1995-03-13	1997-04-30	Synthelabo	Derives de piperidine, leur procede de preparation et leur application en therapeutique
TW382017B (en)	1995-12-27	2000-02-11	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

1997
- 1997-03-05 TW TW086102623A patent/TW527186B/zh not_active IP Right Cessation
- 1997-03-11 CZ CZ19981529A patent/CZ294060B6/cs not_active IP Right Cessation
- 1997-03-11 PL PL97327985A patent/PL193444B1/pl not_active IP Right Cessation
- 1997-03-11 AT AT97908226T patent/ATE241626T1/de not_active IP Right Cessation
- 1997-03-11 WO PCT/EP1997/001264 patent/WO1997034897A1/en not_active Ceased
- 1997-03-11 KR KR1020017008287A patent/KR100349500B1/ko not_active Expired - Fee Related
- 1997-03-11 CA CA002237594A patent/CA2237594C/en not_active Expired - Fee Related
- 1997-03-11 KR KR1019980703754A patent/KR100330698B1/ko not_active Expired - Fee Related
- 1997-03-11 NZ NZ330466A patent/NZ330466A/xx unknown
- 1997-03-11 HU HU9900415A patent/HU224528B1/hu not_active IP Right Cessation
- 1997-03-11 TR TR1998/01191T patent/TR199801191T2/xx unknown
- 1997-03-11 EA EA199800586A patent/EA001004B1/ru unknown
- 1997-03-11 EE EE9800281A patent/EE03773B1/xx not_active IP Right Cessation
- 1997-03-11 JP JP53312197A patent/JP3630434B2/ja not_active Expired - Fee Related
- 1997-03-11 BR BR9708140A patent/BR9708140A/pt not_active IP Right Cessation
- 1997-03-11 DE DE69722389T patent/DE69722389T2/de not_active Expired - Fee Related
- 1997-03-11 IL IL12457297A patent/IL124572A/en not_active IP Right Cessation
- 1997-03-11 CN CN97192399A patent/CN1083453C/zh not_active Expired - Fee Related
- 1997-03-11 EP EP97908226A patent/EP0888352B1/en not_active Expired - Lifetime
- 1997-03-11 ES ES97908226T patent/ES2200159T3/es not_active Expired - Lifetime
- 1997-03-11 US US09/142,932 patent/US6218381B1/en not_active Expired - Fee Related
- 1997-03-11 SK SK662-98A patent/SK284434B6/sk not_active IP Right Cessation
- 1997-03-17 MY MYPI97001123A patent/MY118282A/en unknown
- 1997-03-18 ZA ZA972351A patent/ZA972351B/xx unknown
- 1997-03-18 AR ARP970101072A patent/AR006271A1/es unknown
- 1997-03-19 ID IDP970888A patent/ID16375A/id unknown
- 1997-03-19 HR HR970161A patent/HRP970161B1/xx not_active IP Right Cessation
1998
- 1998-05-11 NO NO19982124A patent/NO310659B1/no not_active IP Right Cessation
- 1998-05-18 BG BG102459A patent/BG62734B1/bg unknown
- 1998-06-03 MX MX9804426A patent/MX9804426A/es not_active IP Right Cessation
2001
- 2001-02-02 US US09/775,524 patent/US6476018B1/en not_active Expired - Fee Related
- 2001-06-01 JP JP2001167003A patent/JP4205319B2/ja not_active Expired - Fee Related
2002
- 2002-07-02 US US10/187,665 patent/US20030087895A1/en not_active Abandoned
2003
- 2003-10-08 JP JP2003349802A patent/JP4251447B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU709683B2 (en)	1999-09-02
TR199801191T2 (xx)	1998-10-21
EA199800586A1 (ru)	1998-12-24
EA001004B1 (ru)	2000-08-28
WO1997034897A1 (en)	1997-09-25
KR100330698B1 (ko)	2002-10-31
HUP9900415A3 (en)	2001-11-28
HUP9900415A2 (hu)	1999-05-28
ID16375A (id)	1997-09-25
JP4205319B2 (ja)	2009-01-07
EE9800281A (et)	1999-02-15
NZ330466A (en)	1999-03-29
BG62734B1 (bg)	2000-06-30
ZA972351B (en)	1998-09-18
US6218381B1 (en)	2001-04-17
JP2004067701A (ja)	2004-03-04
BG102459A (en)	1999-06-30
PL327985A1 (en)	1999-01-04
US20030087895A1 (en)	2003-05-08
CA2237594A1 (en)	1997-09-25
US6476018B1 (en)	2002-11-05
JP2000505477A (ja)	2000-05-09
ATE241626T1 (de)	2003-06-15
HRP970161A2 (en)	1998-04-30
CA2237594C (en)	2006-05-30
NO310659B1 (no)	2001-08-06
EP0888352A1 (en)	1999-01-07
AR006271A1 (es)	1999-08-11
TW527186B (en)	2003-04-11
BR9708140A (pt)	1999-07-27
CN1083453C (zh)	2002-04-24
EP0888352B1 (en)	2003-05-28
JP2002012594A (ja)	2002-01-15
NO982124D0 (no)	1998-05-11
CZ152998A3 (cs)	1999-02-17
AU2026997A (en)	1997-10-10
DE69722389D1 (de)	2003-07-03
SK284434B6 (sk)	2005-04-01
EE03773B1 (et)	2002-06-17
KR20000064358A (ko)	2000-11-06
DE69722389T2 (de)	2009-09-24
HU224528B1 (hu)	2005-10-28
JP3630434B2 (ja)	2005-03-16
SK66298A3 (en)	1999-06-11
KR100349500B1 (ko)	2002-08-21
IL124572A0 (en)	1998-12-06
MY118282A (en)	2004-09-30
ES2200159T3 (es)	2004-03-01
CN1211985A (zh)	1999-03-24
PL193444B1 (pl)	2007-02-28
JP4251447B2 (ja)	2009-04-08
MX9804426A (es)	1998-09-30
HK1015769A1 (en)	1999-10-22
IL124572A (en)	2002-03-10
HRP970161B1 (en)	2002-06-30
CZ294060B6 (cs)	2004-09-15

Publication	Publication Date	Title
PT1019090E (pt)	2004-05-31	Derivados polimeros de camptotecina
DE69718179D1 (de)	2003-02-06	Radauswuchtvorrichtung
PT934320E (pt)	2003-07-31	Derivados de naftiridina
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ID19403A (id)	1998-07-09	Senyawa-senyawa heterosiklik
ID19609A (id)	1998-07-23	Senyawa-senyawa heterosiklik
ID16152A (id)	1997-09-04	Senyawa-senyawa triaril
PT1005446E (pt)	2004-06-30	Derivados de n-aroilfenilalanina
ID15904A (id)	1997-08-14	Senyawa-senyawa tiofenopirimidina
BR9710352A (pt)	1999-08-17	Compostos piridilpirrole
ID18685A (id)	1998-04-30	Senyawa trisiklik tersubstitusi
FI972660L (fi)	1997-08-22	Piperatsini-2,5-dionijohdannaiset monilääke resistanssi modulaattoreina
DE69716924D1 (de)	2002-12-12	Phosphonat-nukleotid-verbindungen
ATE255098T1 (de)	2003-12-15	Substituierte chromanderivate
BR9709065A (pt)	1999-08-03	Derivados de alquilaminobenzotiazole e-benzoxazol
PT1003719E (pt)	2002-10-31	Derivados microbicidas de n-sulfonil-glicinalquiniloxifenemetilamida
PT1027362E (pt)	2005-08-31	Derivados de cetolidos 2-halogeno-6-o-substituidos
PT922050E (pt)	2003-12-31	Derivados de 3-descladinose-2,3-anidroeritromicina
BR9705635A (pt)	1999-05-18	Compostos
ATE255099T1 (de)	2003-12-15	Substituierte chromanderivate
NO982124D0 (no)	1998-05-11	Kondenserte imidazolderivater som multilegemiddel resistanse modulatorer
PT923594E (pt)	2003-02-28	Compostos de bromotiacumicina
PT906279E (pt)	2003-02-28	Derivados de pirrol
PT931087E (pt)	2002-09-30	Novos derivados de piranosido
ATE211884T1 (de)	2002-02-15	Halopropargyl-einschlussverbindungen

Legal Events

Date	Code	Title	Description
2010-11-01	MM1K	Lapsed by not paying the annual fees