NO981282L - Calcitriolderivater og deres anvendelser - Google Patents
Calcitriolderivater og deres anvendelserInfo
- Publication number
- NO981282L NO981282L NO981282A NO981282A NO981282L NO 981282 L NO981282 L NO 981282L NO 981282 A NO981282 A NO 981282A NO 981282 A NO981282 A NO 981282A NO 981282 L NO981282 L NO 981282L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- vitamin
- modified
- calcitriol
- modified compound
- Prior art date
Links
- 150000001668 calcitriol derivatives Chemical class 0.000 title 1
- 229930003316 Vitamin D Natural products 0.000 abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 235000019166 vitamin D Nutrition 0.000 abstract 3
- 239000011710 vitamin D Substances 0.000 abstract 3
- 229940046008 vitamin d Drugs 0.000 abstract 3
- 238000001727 in vivo Methods 0.000 abstract 2
- -1 vitamin D compounds Chemical class 0.000 abstract 2
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 235000020964 calcitriol Nutrition 0.000 abstract 1
- 239000011612 calcitriol Substances 0.000 abstract 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 abstract 1
- 229960005084 calcitriol Drugs 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53186795A | 1995-09-21 | 1995-09-21 | |
| US08/531,403 US5952317A (en) | 1995-09-21 | 1995-09-21 | Calcitriol derivatives and their uses |
| PCT/US1996/015184 WO1997011053A1 (fr) | 1995-09-21 | 1996-09-20 | Derives de calcitriol et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO981282D0 NO981282D0 (no) | 1998-03-20 |
| NO981282L true NO981282L (no) | 1998-05-22 |
Family
ID=27063537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO981282A NO981282L (no) | 1995-09-21 | 1998-03-20 | Calcitriolderivater og deres anvendelser |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1021401A1 (fr) |
| JP (1) | JP3372259B2 (fr) |
| KR (1) | KR100327922B1 (fr) |
| AU (1) | AU717238B2 (fr) |
| CA (1) | CA2229316C (fr) |
| HU (1) | HUP9802303A3 (fr) |
| NO (1) | NO981282L (fr) |
| NZ (2) | NZ319819A (fr) |
| WO (1) | WO1997011053A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795909A (en) | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| AU5305600A (en) * | 1999-08-17 | 2001-03-13 | Wisconsin Alumni Research Foundation | Animal feed containing hydrolyzable calcitriol derivatives |
| KR100317935B1 (ko) * | 1999-10-20 | 2001-12-22 | 유승필 | 대사성 골질환 치료용 약제조성물 및 이의 제조방법 |
| US20020045606A1 (en) | 1999-12-02 | 2002-04-18 | Reddy Satyanarayana G. | Esters of vitamin D3 and uses thereof |
| US20030195175A1 (en) * | 2002-03-25 | 2003-10-16 | Deluca Hector F. | Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone |
| AU2005216651A1 (en) | 2004-03-01 | 2005-09-09 | Bioxell Spa | Treatment of interstitial cystitis with vitamin D compounds |
| WO2006051106A1 (fr) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Emploi combiné de dérivés de vitamine d et d'agents antiproliférants pour le traitement de cancers de la vessie |
| PT3095447T (pt) | 2006-02-03 | 2022-01-24 | Opko Renal Llc | Tratamento da insuficiência e deficiência de vitamina d com 25-hidroxivitamina d2 e 25-hidroxivitamina d3 |
| SI2037936T1 (sl) | 2006-06-21 | 2014-11-28 | Opko Renal, Llc | Postopek zdravljenja in prepreäśevanja sekundarnega hiperparatiroidizma |
| EP3225243B1 (fr) | 2007-04-25 | 2025-09-03 | Opko Renal, LLC | Procédé sûr et efficace de traitement et de prévention de l'hyperparathyroïdisme secondaire dans une maladie rénale chronique |
| EP2148684B1 (fr) | 2007-04-25 | 2013-01-16 | Cytochroma Inc. | Procédé de traitement d'une insuffisance et d'une carence en vitamine d |
| JP5647516B2 (ja) | 2007-04-25 | 2014-12-24 | シトクロマ インコーポレイテッド | ビタミンｄ療法のための方法および化合物 |
| SI2481400T1 (sl) | 2007-04-25 | 2014-11-28 | Opko IP Holdings II, Inc. | Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti nosilec |
| ES2593356T3 (es) | 2008-04-02 | 2016-12-07 | Opko Ireland Global Holdings, Ltd. | Métodos, composiciones, usos y kits útiles para la deficiencia de la vitamina D y trastornos relacionados |
| LT2552484T (lt) | 2010-03-29 | 2020-04-27 | Opko Ireland Global Holdings, Ltd. | Būdai ir kompozicijos, skirti paratiroidų lygiams sumažinti |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
| KR101983654B1 (ko) * | 2018-07-24 | 2019-05-29 | 한국과학기술원 | Cfc 증후군 환자의 발달 저해를 완화할 수 있는 치료용 조성물 |
| CN114656413B (zh) * | 2022-03-30 | 2024-04-09 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物及其制备方法 |
| CN114681467B (zh) * | 2022-03-30 | 2024-03-12 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物在制备抗肿瘤药物中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
| US4206131A (en) * | 1978-06-19 | 1980-06-03 | The Upjohn Company | Compounds and process |
| US4188345A (en) * | 1978-07-26 | 1980-02-12 | Wisconsin Alumni Research Foundation | Fluorovitamin D compounds and processes for their preparation |
| JPS5846508A (ja) * | 1981-09-14 | 1983-03-18 | 日本石油化学株式会社 | 導電性材料の製法 |
| FR2530624B1 (fr) * | 1982-07-26 | 1987-08-07 | Wisconsin Alumni Res Found | Nouveaux analogues de la vitamine d et compositions pharmaceutiques ou veterinaires les contenant |
| JPH0825993B2 (ja) * | 1990-08-20 | 1996-03-13 | 大同ほくさん株式会社 | ビタミンｄ２およびｄ３又は活性型ビタミンｄ２およびｄ３の製造方法，並びにその中間体 |
| JPH05339230A (ja) * | 1992-03-12 | 1993-12-21 | Nisshin Flour Milling Co Ltd | 活性型ビタミンｄ２及びその誘導体の製造法 |
| JP3182215B2 (ja) * | 1992-06-26 | 2001-07-03 | 日清製粉株式会社 | １−アシルオキシビタミンｄ誘導体 |
-
1996
- 1996-09-20 JP JP51294597A patent/JP3372259B2/ja not_active Expired - Fee Related
- 1996-09-20 EP EP96933853A patent/EP1021401A1/fr not_active Withdrawn
- 1996-09-20 WO PCT/US1996/015184 patent/WO1997011053A1/fr not_active Ceased
- 1996-09-20 CA CA002229316A patent/CA2229316C/fr not_active Expired - Fee Related
- 1996-09-20 AU AU72426/96A patent/AU717238B2/en not_active Ceased
- 1996-09-20 NZ NZ319819A patent/NZ319819A/en unknown
- 1996-09-20 NZ NZ501318A patent/NZ501318A/en unknown
- 1996-09-20 HU HU9802303A patent/HUP9802303A3/hu unknown
- 1996-09-20 KR KR1019980702077A patent/KR100327922B1/ko not_active Expired - Fee Related
-
1998
- 1998-03-20 NO NO981282A patent/NO981282L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9802303A2 (hu) | 1999-02-01 |
| NO981282D0 (no) | 1998-03-20 |
| EP1021401A1 (fr) | 2000-07-26 |
| CA2229316A1 (fr) | 1997-03-27 |
| KR19990063628A (ko) | 1999-07-26 |
| WO1997011053A1 (fr) | 1997-03-27 |
| AU7242696A (en) | 1997-04-09 |
| KR100327922B1 (ko) | 2002-05-09 |
| JP3372259B2 (ja) | 2003-01-27 |
| HUP9802303A3 (en) | 1999-05-28 |
| CA2229316C (fr) | 2005-04-12 |
| NZ319819A (en) | 2000-02-28 |
| MX9801943A (es) | 1998-08-30 |
| NZ501318A (en) | 2001-07-27 |
| JPH11511475A (ja) | 1999-10-05 |
| AU717238B2 (en) | 2000-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |