NO980594L - Fremgangsmåte for rensingen av et intermediat i fremstillingen av iopamidol - Google Patents

Fremgangsmåte for rensingen av et intermediat i fremstillingen av iopamidol

Info

Publication number: NO980594L
Authority: NO; Norway
Prior art keywords: purification; iopamidol; preparation; triiodo; oxopropyl
Prior art date: 1996-06-13

Application number

NO980594A

Other languages

English (en)

Other versions

NO980594D0 (no

NO324342B1 (no

Inventor

Nicola Desantis

Original Assignee

Fructamine Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-13

Filing date

1998-02-11

Publication date

1998-04-07

1998-02-11 Application filed by Fructamine Spa filed Critical Fructamine Spa

1998-02-11 Publication of NO980594D0 publication Critical patent/NO980594D0/no

1998-04-07 Publication of NO980594L publication Critical patent/NO980594L/no

2007-09-24 Publication of NO324342B1 publication Critical patent/NO324342B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Removal Of Specific Substances (AREA)
Carbon And Carbon Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO19980594A 1996-06-13 1998-02-11 Fremgangsmate ved fremstilling av (S)-N, N'-bis((2-hydroksy-1-(hydroksymetyl)etyl)-5-((2-hydroksy-1-oksopropyl)amino)-2,4,6-trijod-1,3-benzendikarboksamid NO324342B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT96MI001204A IT1288114B1 (it)	1996-06-13	1996-06-13	Processo per la purificazione di un intermedio
PCT/EP1997/003021 WO1997047590A2 (en)	1996-06-13	1997-06-11	Process for the purification of an intermediate in the preparation of iopamidol

Publications (3)

Publication Number	Publication Date
NO980594D0 NO980594D0 (no)	1998-02-11
NO980594L true NO980594L (no)	1998-04-07
NO324342B1 NO324342B1 (no)	2007-09-24

Family

ID=11374420

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19980594A NO324342B1 (no)	1996-06-13	1998-02-11	Fremgangsmate ved fremstilling av (S)-N, N'-bis((2-hydroksy-1-(hydroksymetyl)etyl)-5-((2-hydroksy-1-oksopropyl)amino)-2,4,6-trijod-1,3-benzendikarboksamid

Country Status (17)

Country	Link
US (1)	US5849953A (no)
EP (1)	EP0851854B1 (no)
JP (1)	JP4018751B2 (no)
CN (1)	CN1089335C (no)
AT (1)	ATE210630T1 (no)
AU (1)	AU3094597A (no)
CZ (1)	CZ293956B6 (no)
DE (1)	DE69709044T2 (no)
ES (1)	ES2165610T3 (no)
HU (1)	HU227980B1 (no)
IL (1)	IL123259A (no)
IN (1)	IN182809B (no)
IT (1)	IT1288114B1 (no)
NO (1)	NO324342B1 (no)
PT (1)	PT851854E (no)
WO (1)	WO1997047590A2 (no)
ZA (1)	ZA975203B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1299202B1 (it) *	1998-05-08	2000-02-29	Dibra Spa	Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
IT1302200B1 (it)	1998-09-11	2000-07-31	Dibra Spa	PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
DE102007053531B4 (de) *	2007-11-09	2010-10-21	Hs Genion Gmbh	Rolloeinrichtung
EP2230227A1 (en)	2009-03-20	2010-09-22	Bracco Imaging S.p.A	Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en)	2009-04-21	2010-10-27	Bracco Imaging S.p.A	Process for the iodination of aromatic compounds
IT1403988B1 (it) *	2010-07-15	2013-11-08	Bracco Imaging Spa	Processo per la preparazione di agenti di contrasto.
PL2931696T3 (pl)	2012-12-11	2019-01-31	Bracco Imaging S.P.A	Ciągły sposób otrzymywania kwasu (S)-2-acetyloksypropionowego
SI3066071T1 (en)	2013-11-05	2018-08-31	Bracco Imaging S.P.A.	Preparation of jopamidol
HUE049284T2 (hu)	2014-06-10	2020-09-28	Bracco Imaging Spa	Eljárás (S)-2-acetiloxipropionsav és származékai elõállítására
PT108524B (pt) *	2015-06-02	2017-12-15	Hovione Farmaciência S A	Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
JP7012722B2 (ja)	2016-12-05	2022-01-28	ブラッコ・イメージング・ソシエタ・ペル・アチオニ	放射線画像診断剤中間体の機械化学的合成

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3324107A (en) *	1964-03-27	1967-06-06	Du Pont	Dialkylamide purification
US3576870A (en) *	1967-07-05	1971-04-27	Du Pont	Process for purifying n,n-dimethylacetamide
CH608189A5 (no) *	1974-12-13	1978-12-29	Savac Ag
CH616403A5 (en) *	1975-10-29	1980-03-31	Bracco Ind Chimica Spa	Process for the preparation of 2,4,6-triodoisophthalamides which are readily soluble in water.
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
GB2088850B (en) *	1980-12-09	1983-09-28	Coal Industry Patents Ltd	Treatment of n-methyl pyrrolidone
IT1256162B (it) *	1992-10-27	1995-11-29	Zambon Spa	Processo per la preparazione di un intermedio della sintesi organica

1996
- 1996-06-13 IT IT96MI001204A patent/IT1288114B1/it active IP Right Grant
1997
- 1997-06-11 JP JP50119798A patent/JP4018751B2/ja not_active Expired - Lifetime
- 1997-06-11 CN CN97190690A patent/CN1089335C/zh not_active Expired - Lifetime
- 1997-06-11 ES ES97925993T patent/ES2165610T3/es not_active Expired - Lifetime
- 1997-06-11 IL IL12325997A patent/IL123259A/xx not_active IP Right Cessation
- 1997-06-11 WO PCT/EP1997/003021 patent/WO1997047590A2/en not_active Ceased
- 1997-06-11 DE DE69709044T patent/DE69709044T2/de not_active Expired - Lifetime
- 1997-06-11 EP EP97925993A patent/EP0851854B1/en not_active Expired - Lifetime
- 1997-06-11 PT PT97925993T patent/PT851854E/pt unknown
- 1997-06-11 AU AU30945/97A patent/AU3094597A/en not_active Abandoned
- 1997-06-11 HU HU9901631A patent/HU227980B1/hu unknown
- 1997-06-11 AT AT97925993T patent/ATE210630T1/de not_active IP Right Cessation
- 1997-06-11 CZ CZ1998399A patent/CZ293956B6/cs not_active IP Right Cessation
- 1997-06-12 ZA ZA9705203A patent/ZA975203B/xx unknown
- 1997-06-12 US US08/873,771 patent/US5849953A/en not_active Expired - Lifetime
- 1997-06-13 IN IN1291MA1997 patent/IN182809B/en unknown
1998
- 1998-02-11 NO NO19980594A patent/NO324342B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ITMI961204A0 (no)	1996-06-13
IL123259A0 (en)	1998-09-24
HUP9901631A3 (en)	2001-02-28
CN1195338A (zh)	1998-10-07
ZA975203B (en)	1998-01-20
ITMI961204A1 (it)	1997-12-13
CZ39998A3 (cs)	1998-07-15
IN182809B (no)	1999-07-24
IL123259A (en)	2000-07-16
WO1997047590A2 (en)	1997-12-18
IT1288114B1 (it)	1998-09-10
CZ293956B6 (cs)	2004-08-18
HU227980B1 (en)	2012-07-30
CN1089335C (zh)	2002-08-21
NO980594D0 (no)	1998-02-11
EP0851854B1 (en)	2001-12-12
EP0851854A2 (en)	1998-07-08
AU3094597A (en)	1998-01-07
JP4018751B2 (ja)	2007-12-05
NO324342B1 (no)	2007-09-24
DE69709044D1 (de)	2002-01-24
ATE210630T1 (de)	2001-12-15
JPH11510827A (ja)	1999-09-21
HUP9901631A2 (hu)	1999-08-30
PT851854E (pt)	2002-06-28
US5849953A (en)	1998-12-15
WO1997047590A3 (en)	1998-04-02
ES2165610T3 (es)	2002-03-16
DE69709044T2 (de)	2002-08-22

Publication	Publication Date	Title
NO980594L (no)	1998-04-07	Fremgangsmåte for rensingen av et intermediat i fremstillingen av iopamidol
PT1150943E (pt)	2004-02-27	Preparacao de iodixanol
DE69203623D1 (de)	1995-08-31	Ceramide, Verfahren zu ihrer Herstellung und ihre Verwendungen in Kosmetik und Dermopharmazie.
MX9200206A (es)	1992-08-01	1,2,3,4- TETRAHIDROCICLOPENT (b) INDOLES SUSBSTITUIDOS, 1,2,3,3a-4,8a- HEXAHIDROCICLOPENT (b) INDOLES Y COMPUESTOS RELACIONADOS, COMPUESTOS INTERMEDIOS Y UN PROCEDIMIENTO PARA LA PREPARACIONDE LOS MISMOS Y SU USO COMO MEDICAMENTOS.
GR3001816T3 (en)	1992-11-23	Process for the preparation of thienylethyl amines, and dithienylethyl amines so obtained
HUP9700667A2 (hu)	1999-06-28	Eljárás egy jódozott kontrasztanyag, a jopamidol szintézisében alkalmazható közbenső termék előállítására és ennek felhasználásával iopamidol előállítására
CA2229470A1 (en)	1997-12-18	Process for the purification of an intermediate in the preparation of iopamidol
BR9606624A (pt)	1997-11-11	Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água
NO20011241D0 (no)	2001-03-12	FremgangsmÕte ved fremstilling av S-N,N'-bis[2-hydroksy-1-
BR0004965A (pt)	2001-06-19	Processo para preparação de compostos de cromano esterificados
FR2881128B1 (fr)	2007-03-23	Nouvelle methode de synthese de la zeolithe zbm-30 a partir d'un melange de composes amines
DE69919382D1 (de)	2004-09-16	Herstellung von 5-amino-isophthalamiden
NO993851D0 (no)	1999-08-10	Fremgangsmåte ved krystallisering fra en lineaer eller forgrenet (C5-C6) alkohol eller deres blandinger av (S)-N,N'-bis[2-hydroksy-1-(hydroksymetyl)etyl]-5-[(2-hydroksy-1-oksopropyl)amino]-2,4,6-trijod-1,3-benzendikarboksamid

Legal Events

Date	Code	Title	Description
2017-07-10	MK1K	Patent expired