NO985970L - Indolinderivater anvendelige som 5_HT-2C-reseptor-antagonister - Google Patents

Indolinderivater anvendelige som 5_HT-2C-reseptor-antagonister

Info

Publication number: NO985970L
Authority: NO; Norway
Prior art keywords: receptor antagonists; derivatives useful; indoline derivatives; indoline; useful
Prior art date: 1996-06-20

Application number

NO985970A

Other languages

English (en)

Other versions

NO985970D0 (no

NO316756B1 (no

Inventor

Steven Mark Bromidge

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-20

Filing date

1998-12-18

Publication date

1998-12-18

1998-12-18 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1998-12-18 Publication of NO985970D0 publication Critical patent/NO985970D0/no

1998-12-18 Publication of NO985970L publication Critical patent/NO985970L/no

2004-04-26 Publication of NO316756B1 publication Critical patent/NO316756B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

NO19985970A 1996-06-20 1998-12-18 Indolinderivater, deres fremstilling og anvendelse, og farmasoytiske preparater inneholdende dem NO316756B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9612885.5A GB9612885D0 (en)	1996-06-20	1996-06-20	Novel compounds
PCT/EP1997/003157 WO1997048700A1 (en)	1996-06-20	1997-06-16	Indoline derivatives useful as 5-ht-2c receptor antagonists

Publications (3)

Publication Number	Publication Date
NO985970D0 NO985970D0 (no)	1998-12-18
NO985970L true NO985970L (no)	1998-12-18
NO316756B1 NO316756B1 (no)	2004-04-26

Family

ID=10795577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19985970A NO316756B1 (no)	1996-06-20	1998-12-18	Indolinderivater, deres fremstilling og anvendelse, og farmasoytiske preparater inneholdende dem

Country Status (27)

Country	Link
US (2)	US6313145B1 (no)
EP (1)	EP0912556B1 (no)
JP (1)	JP2000512644A (no)
KR (1)	KR20040101563A (no)
CN (1)	CN1147485C (no)
AR (1)	AR008244A1 (no)
AT (1)	ATE196766T1 (no)
AU (1)	AU718000B2 (no)
BR (1)	BR9709982A (no)
CA (1)	CA2258559A1 (no)
CO (1)	CO4870758A1 (no)
CZ (1)	CZ289799B6 (no)
DE (1)	DE69703242T2 (no)
DK (1)	DK0912556T3 (no)
ES (1)	ES2152682T3 (no)
GB (1)	GB9612885D0 (no)
GR (1)	GR3034847T3 (no)
HU (1)	HUP9903480A3 (no)
IL (1)	IL127304A (no)
NO (1)	NO316756B1 (no)
NZ (1)	NZ332840A (no)
PL (1)	PL186885B1 (no)
PT (1)	PT912556E (no)
TR (1)	TR199802552T2 (no)
TW (1)	TW360650B (no)
WO (1)	WO1997048700A1 (no)
ZA (1)	ZA975416B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9710523D0 (en) *	1997-05-23	1997-07-16	Smithkline Beecham Plc	Novel compounds
AU3030899A (en) *	1998-02-25	1999-09-15	Smithkline Beecham Plc	Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives
GB0019950D0 (en) *	2000-08-12	2000-09-27	Smithkline Beecham Plc	Compounds
US20030008880A1 (en) *	2001-05-02	2003-01-09	Pfizer Inc.	4-(2-Pyridyl) piperizines having 5HT7 receptor agonist activity
MXPA04005151A (es)	2001-11-28	2004-08-11	Upjohn Co	Compuestos terapeuticos.
GB0200283D0 (en) *	2002-01-08	2002-02-20	Smithkline Beecham Plc	Compounds
WO2003076426A2 (en)	2002-03-04	2003-09-18	Pharmacia & Upjohn Company	Pyridinyloxy derivatives as 5-ht receptor ligands
WO2003089409A1 (en) *	2002-04-19	2003-10-30	Glaxo Group Limited	Compounds having affinity at 5ht2c receptor and use thereof in therapy
GB0305024D0 (en) *	2003-03-05	2003-04-09	Glaxo Group Ltd	Compounds
GB0305553D0 (en) *	2003-03-11	2003-04-16	Glaxo Group Ltd	Compounds
KR101062376B1 (ko) *	2008-04-10	2011-09-06	한국화학연구원	신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
CA2749783A1 (en)	2009-01-16	2010-07-22	Massachusetts Institute Of Technology	Diagnosis and treatment of autism spectrum disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2142721A1 (en) *	1992-08-20	1994-03-03	Ian T. Forbes	Condensed indole derivatives as 5ht and 5ht antagonists
GB9313913D0 (en)	1993-07-06	1993-08-18	Smithkline Beecham Plc	Novel compounds
EP0807104A2 (en)	1995-02-02	1997-11-19	Smithkline Beecham Plc	Heterocyclic compounds possessing 5ht 2c? receptor antagonist activity
PL184490B1 (pl) *	1995-02-02	2002-11-29	Smithkline Beecham Plc	Nowe pochodne indolu jako antagonista receptora T
GB9607219D0 (en)	1996-04-04	1996-06-12	Smithkline Beecham Plc	Novel compounds
US6028055A (en)	1996-10-22	2000-02-22	Genetech, Inc.	Receptor selective BNP

1996
- 1996-06-20 GB GBGB9612885.5A patent/GB9612885D0/en active Pending
1997
- 1997-06-16 NZ NZ332840A patent/NZ332840A/xx unknown
- 1997-06-16 AT AT97929202T patent/ATE196766T1/de not_active IP Right Cessation
- 1997-06-16 ES ES97929202T patent/ES2152682T3/es not_active Expired - Lifetime
- 1997-06-16 HU HU9903480A patent/HUP9903480A3/hu not_active Application Discontinuation
- 1997-06-16 EP EP97929202A patent/EP0912556B1/en not_active Expired - Lifetime
- 1997-06-16 BR BR9709982A patent/BR9709982A/pt not_active Application Discontinuation
- 1997-06-16 DK DK97929202T patent/DK0912556T3/da active
- 1997-06-16 DE DE69703242T patent/DE69703242T2/de not_active Expired - Fee Related
- 1997-06-16 KR KR10-2004-7017304A patent/KR20040101563A/ko not_active Abandoned
- 1997-06-16 CA CA002258559A patent/CA2258559A1/en not_active Abandoned
- 1997-06-16 AU AU33396/97A patent/AU718000B2/en not_active Ceased
- 1997-06-16 TR TR1998/02552T patent/TR199802552T2/xx unknown
- 1997-06-16 PT PT97929202T patent/PT912556E/pt unknown
- 1997-06-16 CN CNB971955395A patent/CN1147485C/zh not_active Expired - Fee Related
- 1997-06-16 US US09/202,772 patent/US6313145B1/en not_active Expired - Fee Related
- 1997-06-16 PL PL97330708A patent/PL186885B1/pl not_active IP Right Cessation
- 1997-06-16 WO PCT/EP1997/003157 patent/WO1997048700A1/en not_active Ceased
- 1997-06-16 JP JP10502260A patent/JP2000512644A/ja not_active Ceased
- 1997-06-16 IL IL12730497A patent/IL127304A/xx not_active IP Right Cessation
- 1997-06-16 CZ CZ19984204A patent/CZ289799B6/cs not_active IP Right Cessation
- 1997-06-18 AR ARP970102675A patent/AR008244A1/es active IP Right Grant
- 1997-06-19 ZA ZA975416A patent/ZA975416B/xx unknown
- 1997-06-19 TW TW086108550A patent/TW360650B/zh active
- 1997-06-20 CO CO97034433A patent/CO4870758A1/es unknown
1998
- 1998-12-18 NO NO19985970A patent/NO316756B1/no unknown
2000
- 2000-11-14 GR GR20000402536T patent/GR3034847T3/el not_active IP Right Cessation
2001
- 2001-09-06 US US09/948,289 patent/US20020035134A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO985970D0 (no)	1998-12-18
EP0912556A1 (en)	1999-05-06
TW360650B (en)	1999-06-11
CN1222152A (zh)	1999-07-07
KR20040101563A (ko)	2004-12-02
HUP9903480A2 (en)	2000-07-28
ATE196766T1 (de)	2000-10-15
NO316756B1 (no)	2004-04-26
GR3034847T3 (en)	2001-02-28
HK1019744A1 (en)	2000-02-25
IL127304A0 (en)	1999-09-22
US20020035134A1 (en)	2002-03-21
BR9709982A (pt)	1999-08-10
US6313145B1 (en)	2001-11-06
CA2258559A1 (en)	1997-12-24
DE69703242D1 (de)	2000-11-09
DK0912556T3 (da)	2001-01-22
JP2000512644A (ja)	2000-09-26
PL330708A1 (en)	1999-05-24
AR008244A1 (es)	1999-12-29
HUP9903480A3 (en)	2002-12-28
CZ420498A3 (cs)	1999-05-12
DE69703242T2 (de)	2001-03-08
ZA975416B (en)	1999-01-25
PT912556E (pt)	2001-02-28
PL186885B1 (pl)	2004-03-31
NZ332840A (en)	2000-05-26
CN1147485C (zh)	2004-04-28
EP0912556B1 (en)	2000-10-04
ES2152682T3 (es)	2001-02-01
CZ289799B6 (cs)	2002-04-17
AU3339697A (en)	1998-01-07
AU718000B2 (en)	2000-04-06
WO1997048700A1 (en)	1997-12-24
GB9612885D0 (en)	1996-08-21
CO4870758A1 (es)	1999-12-27
TR199802552T2 (xx)	1999-02-22
IL127304A (en)	2003-07-06

Publication	Publication Date	Title
NO985225L (no)	1998-11-09	Indolderivater nyttige som endotelinreseptorantagonister
FI973205A0 (fi)	1997-08-01	Indolijohdannaisia 5-HT-reseptoriantagonisteina
DK0630376T3 (da)	1999-06-23	Kondenserede indolderivater som 5-HT4-receptorantagonister
DK0804419T3 (da)	2003-11-24	Quinolinderivater som tachykinin NK 3-receptor-antagonister
DK0856001T3 (da)	2002-12-30	Pyrimidinderivater som 5-HT2C-receptor-antagonister
DE69734833D1 (de)	2006-01-12	Vitronektin rezeptor antagonisten
FI961628A7 (fi)	1996-04-12	Indolijohdannaisia NMDA-antagonisteina
NO974043L (no)	1997-11-03	Indolderivater som EAA-antagonister
DK0906294T3 (da)	2003-05-05	Benzoxazinon-dopamin D4-receptor-antagonister
NO985970L (no)	1998-12-18	Indolinderivater anvendelige som 5_HT-2C-reseptor-antagonister
FI951798A0 (fi)	1995-04-13	Bentsofuraanijohdannaiset 5-HT1-kaltaisina reseptoriantagonisteina
NO985972D0 (no)	1998-12-18	Indolinderivater anvendelige som 5-HT-2C reseptorantagonister
NO963775D0 (no)	1996-09-09	Indol-derivater som CCK-reseptorantagonister
SI0912556T1 (en)	2001-02-28	Indoline derivatives useful as 5-ht-2c receptor antagonists
HK1019747A (en)	2000-02-25	Indoline derivatives useful as 5-ht-2c receptor antagonists