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NO985551L - FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid) - Google Patents

FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid)

Info

Publication number
NO985551L
NO985551L NO985551A NO985551A NO985551L NO 985551 L NO985551 L NO 985551L NO 985551 A NO985551 A NO 985551A NO 985551 A NO985551 A NO 985551A NO 985551 L NO985551 L NO 985551L
Authority
NO
Norway
Prior art keywords
hydrazinecarboximidamide
ethanediylidene
bis
methyl
preparation
Prior art date
Application number
NO985551A
Other languages
English (en)
Other versions
NO985551D0 (no
Inventor
Richard Philion
Steven A Elenbaas
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO985551D0 publication Critical patent/NO985551D0/no
Publication of NO985551L publication Critical patent/NO985551L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Fremgangsmåte for fremstilling av 2,2'-(l-metyl-l,2-etandiyliden)bis[hydrazinkarboks-imidamid] ved: a) omsetning av aminoguanidinhydroklorid med metylglyoksalaldehyd eller metylglyoksaldimetylacetal; og b) rensing av 2,2'-(l-metyl-l,2-etandiyliden)bis [hydrazinkarboksimidamid]-forbindelsen ved krystallisering fra et surt vandig-isopropylalkohol-medium.
NO985551A 1996-05-30 1998-11-27 FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid) NO985551L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/655,518 US5693673A (en) 1996-05-30 1996-05-30 Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bis hydrazine caroximidamide!
PCT/US1997/008347 WO1997045110A1 (en) 1996-05-30 1997-05-19 Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bis[hydrazine carboximidamide]

Publications (2)

Publication Number Publication Date
NO985551D0 NO985551D0 (no) 1998-11-27
NO985551L true NO985551L (no) 1999-01-28

Family

ID=24629215

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985551A NO985551L (no) 1996-05-30 1998-11-27 FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid)

Country Status (8)

Country Link
US (1) US5693673A (no)
EP (1) EP0782983A2 (no)
JP (1) JP2000511181A (no)
AU (1) AU3008497A (no)
BR (1) BR9710170A (no)
CA (1) CA2252606A1 (no)
NO (1) NO985551L (no)
WO (1) WO1997045110A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102924339B (zh) * 2012-11-23 2014-06-04 温州澳珀化工有限公司 一种制备米托胍腙的方法
CN119874620A (zh) * 2025-03-24 2025-04-25 中国科学院过程工程研究所 一种酰胺肼类化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355491A (en) * 1965-09-09 1967-11-28 Dow Chemical Co 1, 2-ethylenebis
US4520031A (en) * 1981-06-01 1985-05-28 The United States Of America As Represented By The Secretary Of Department Of Health And Human Services Method for reducing toxic effects of methyl-glyoxal bis-guanylhydrazone

Also Published As

Publication number Publication date
CA2252606A1 (en) 1997-12-04
AU3008497A (en) 1998-01-05
JP2000511181A (ja) 2000-08-29
WO1997045110A1 (en) 1997-12-04
EP0782983A2 (en) 1997-07-09
US5693673A (en) 1997-12-02
BR9710170A (pt) 1999-08-10
NO985551D0 (no) 1998-11-27

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application