NO984508D0 - Tiazolinsyre-derivater - Google Patents
Tiazolinsyre-derivaterInfo
- Publication number
- NO984508D0 NO984508D0 NO984508A NO984508A NO984508D0 NO 984508 D0 NO984508 D0 NO 984508D0 NO 984508 A NO984508 A NO 984508A NO 984508 A NO984508 A NO 984508A NO 984508 D0 NO984508 D0 NO 984508D0
- Authority
- NO
- Norway
- Prior art keywords
- thiazoline derivatives
- thiazoline
- derivatives
- chelators
- useful
- Prior art date
Links
- 150000003549 thiazolines Chemical class 0.000 title 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/624,289 US5840739A (en) | 1992-11-16 | 1996-03-29 | Thiazoline acid derivatives |
| PCT/US1997/004666 WO1997036885A1 (en) | 1996-03-29 | 1997-03-31 | Thiazoline acid derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO984508D0 true NO984508D0 (no) | 1998-09-28 |
| NO984508L NO984508L (no) | 1998-11-23 |
| NO315608B1 NO315608B1 (no) | 2003-09-29 |
Family
ID=24501405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19984508A NO315608B1 (no) | 1996-03-29 | 1998-09-28 | Tiazolinsyre-derivater, anvendelse av dem og farmasöytiske preparater inneholdende dem |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5840739A (no) |
| EP (3) | EP1380577B1 (no) |
| JP (2) | JP3800559B2 (no) |
| KR (1) | KR20000005100A (no) |
| AT (1) | ATE449088T1 (no) |
| AU (1) | AU715889B2 (no) |
| BR (1) | BR9708460A (no) |
| CA (1) | CA2250243C (no) |
| DE (1) | DE69739670D1 (no) |
| NO (1) | NO315608B1 (no) |
| NZ (2) | NZ509967A (no) |
| PL (1) | PL329172A1 (no) |
| WO (1) | WO1997036885A1 (no) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045531B1 (en) | 1997-03-11 | 2006-05-16 | The General Hospital Corporation | Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator |
| EP1052985B1 (en) * | 1998-02-04 | 2004-12-22 | University Of Florida Research Foundation, Inc. | N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and sodium salts thereof for iron chelating therapy |
| US6323218B1 (en) | 1998-03-11 | 2001-11-27 | The General Hospital Corporation | Agents for use in the treatment of Alzheimer's disease |
| US6638711B1 (en) | 1999-04-29 | 2003-10-28 | The General Hospital Corporation | Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation |
| US6083966A (en) | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
| US6159983A (en) * | 1998-09-18 | 2000-12-12 | University Of Florida | Method and composition for treatment of inflammatory bowel disease |
| NZ509172A (en) * | 1998-09-21 | 2004-02-27 | Univ Florida | Antimalarial agents |
| EP1488791A3 (en) * | 1998-09-21 | 2005-04-06 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
| CA2394524A1 (en) | 1999-12-21 | 2001-06-28 | Raymond J. Bergeron | N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy |
| US6689788B1 (en) * | 2000-08-25 | 2004-02-10 | University Of Florida | Method and composition for treatment of inflammatory bowel disease |
| US6878828B2 (en) | 2002-05-15 | 2005-04-12 | Genzyme Corporation | Synthesis of 2-alkylcysteine via substituted thiazoline ester |
| US20040044220A1 (en) * | 2002-08-22 | 2004-03-04 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| US20040132789A1 (en) * | 2002-08-22 | 2004-07-08 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| AU2003267245C1 (en) | 2002-09-20 | 2008-05-29 | Promega Corporation | Luminescence-based methods and probes for measuring cytochrome P450 activity |
| WO2005034949A1 (en) * | 2003-09-09 | 2005-04-21 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
| TR201910900T4 (tr) | 2005-04-04 | 2019-08-21 | Univ Florida | Desferritiyokin polieter analogları. |
| EP2272973B1 (en) * | 2005-05-31 | 2015-05-27 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| CN101687825B (zh) | 2007-03-15 | 2014-04-23 | 佛罗里达大学研究基金公司 | 去铁硫辛聚醚类似物 |
| JP5597200B2 (ja) | 2008-08-18 | 2014-10-01 | プロメガ コーポレイション | ルミネッセンスを生じる化合物およびチトクロムｐ４５０３ａ酵素を検出するための方法 |
| EP2459544A4 (en) * | 2009-07-27 | 2012-12-05 | Ferrokin Biosciences Inc | DESDAADESFERROTHIOCIN POLYETHERAL ANALOGUE PROGRUGS USING METAL CHLORIDE |
| CN104114170B (zh) | 2011-12-16 | 2021-07-06 | 佛罗里达大学研究基金会 | 4′-去铁硫素类似物的用途 |
| JP6838966B2 (ja) | 2013-11-22 | 2021-03-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | デスフェリチオシン類似体およびその使用 |
| US9790537B2 (en) | 2014-01-29 | 2017-10-17 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| CN107708693A (zh) | 2015-04-27 | 2018-02-16 | 佛罗里达大学研究基金会 | 代谢程序化的金属螯合剂及其用途 |
| BR112020024261B8 (pt) | 2018-05-29 | 2022-05-17 | Cersci Therapeutics Inc | Composto de fórmula (ia) e composição farmacêutica |
| JP2022531453A (ja) | 2019-05-10 | 2022-07-06 | セルシィ セラピューティクス，インコーポレーテッド | チアゾリン抗痛覚過敏薬の製造方法及び多形体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1137529A (en) * | 1967-05-04 | 1968-12-27 | Wyeth John & Brother Ltd | Thiazole compositions |
| CY800A (en) * | 1968-04-09 | 1976-12-01 | Wyeth John & Brother Ltd | Novel thiazoline derivatives, the preparation thereof and compositions containing the same |
| DE3002989A1 (de) * | 1980-01-29 | 1981-07-30 | Hoechst Ag, 6000 Frankfurt | Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels |
| DE3170401D1 (en) * | 1980-07-28 | 1985-06-13 | Ciba Geigy Ag | Triazoline derivatives and processes for their preparation |
| US5393777A (en) * | 1990-11-15 | 1995-02-28 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Deferration using anguibactin siderophore |
| AU5602594A (en) * | 1992-11-16 | 1994-06-08 | University Of Florida Research Foundation, Inc. | 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives |
-
1996
- 1996-03-29 US US08/624,289 patent/US5840739A/en not_active Expired - Fee Related
-
1997
- 1997-03-31 PL PL97329172A patent/PL329172A1/xx unknown
- 1997-03-31 EP EP03021526A patent/EP1380577B1/en not_active Expired - Lifetime
- 1997-03-31 EP EP09160649A patent/EP2096112A3/en not_active Withdrawn
- 1997-03-31 CA CA002250243A patent/CA2250243C/en not_active Expired - Fee Related
- 1997-03-31 AU AU25410/97A patent/AU715889B2/en not_active Ceased
- 1997-03-31 KR KR1019980707738A patent/KR20000005100A/ko not_active Ceased
- 1997-03-31 NZ NZ509967A patent/NZ509967A/en unknown
- 1997-03-31 WO PCT/US1997/004666 patent/WO1997036885A1/en not_active Ceased
- 1997-03-31 EP EP97916924A patent/EP0900209A4/en not_active Withdrawn
- 1997-03-31 NZ NZ332049A patent/NZ332049A/en unknown
- 1997-03-31 AT AT03021526T patent/ATE449088T1/de not_active IP Right Cessation
- 1997-03-31 DE DE69739670T patent/DE69739670D1/de not_active Expired - Fee Related
- 1997-03-31 BR BR9708460-3A patent/BR9708460A/pt not_active Application Discontinuation
- 1997-03-31 JP JP53533897A patent/JP3800559B2/ja not_active Expired - Fee Related
-
1998
- 1998-09-28 NO NO19984508A patent/NO315608B1/no not_active IP Right Cessation
-
2006
- 2006-03-13 JP JP2006067600A patent/JP2006152004A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000505086A (ja) | 2000-04-25 |
| KR20000005100A (ko) | 2000-01-25 |
| US5840739A (en) | 1998-11-24 |
| EP0900209A4 (en) | 2001-09-19 |
| PL329172A1 (en) | 1999-03-15 |
| NZ332049A (en) | 2001-04-27 |
| EP2096112A3 (en) | 2009-09-09 |
| EP2096112A2 (en) | 2009-09-02 |
| NO984508L (no) | 1998-11-23 |
| NO315608B1 (no) | 2003-09-29 |
| ATE449088T1 (de) | 2009-12-15 |
| CA2250243A1 (en) | 1997-10-09 |
| WO1997036885A1 (en) | 1997-10-09 |
| AU715889B2 (en) | 2000-02-10 |
| AU2541097A (en) | 1997-10-22 |
| EP0900209A1 (en) | 1999-03-10 |
| JP2006152004A (ja) | 2006-06-15 |
| EP1380577B1 (en) | 2009-11-18 |
| JP3800559B2 (ja) | 2006-07-26 |
| EP1380577A1 (en) | 2004-01-14 |
| BR9708460A (pt) | 2000-01-04 |
| NZ509967A (en) | 2005-06-24 |
| DE69739670D1 (de) | 2009-12-31 |
| CA2250243C (en) | 2002-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |