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NO984290L - Pharmaceutically useful compounds - Google Patents

Pharmaceutically useful compounds

Info

Publication number
NO984290L
NO984290L NO984290A NO984290A NO984290L NO 984290 L NO984290 L NO 984290L NO 984290 A NO984290 A NO 984290A NO 984290 A NO984290 A NO 984290A NO 984290 L NO984290 L NO 984290L
Authority
NO
Norway
Prior art keywords
pharmaceutically useful
useful compounds
compounds
arylpyrazolisoquinoline
pharmaceuticals
Prior art date
Application number
NO984290A
Other languages
Norwegian (no)
Other versions
NO984290D0 (en
Inventor
John Bantick
Roger Bonnert
Peter Cage
David Donald
Mark Furber
Simon Hirst
Matthew Perry
Eifion Phillips
Original Assignee
Astra Pharma Prod
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605803.7A external-priority patent/GB9605803D0/en
Priority claimed from GBGB9610474.0A external-priority patent/GB9610474D0/en
Priority claimed from GBGB9610894.9A external-priority patent/GB9610894D0/en
Priority claimed from GBGB9700862.7A external-priority patent/GB9700862D0/en
Application filed by Astra Pharma Prod, Astra Ab filed Critical Astra Pharma Prod
Publication of NO984290D0 publication Critical patent/NO984290D0/en
Publication of NO984290L publication Critical patent/NO984290L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

2-arylpyrazolisokinolin- og -cinnolinonderivater, fremgangsmåter for deres fremstilling, deres anvendelse som legemidler, og farmasøytiske formuleringer inneholdende disse forbindelsene.2-arylpyrazolisoquinoline and quinolinone derivatives, processes for their preparation, their use as pharmaceuticals, and pharmaceutical formulations containing these compounds.

NO984290A 1996-03-20 1998-09-16 Pharmaceutically useful compounds NO984290L (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9605803.7A GB9605803D0 (en) 1996-03-20 1996-03-20 Pharmaceutically-active compound
GBGB9610474.0A GB9610474D0 (en) 1996-05-18 1996-05-18 Pharmaceutically active compounds
GBGB9610894.9A GB9610894D0 (en) 1996-05-24 1996-05-24 Pharmaceutically useful compounds
GBGB9700862.7A GB9700862D0 (en) 1997-01-16 1997-01-16 Pharmaceutically useful compounds
PCT/SE1997/000471 WO1997034893A1 (en) 1996-03-20 1997-03-20 Pharmaceutically useful compounds

Publications (2)

Publication Number Publication Date
NO984290D0 NO984290D0 (en) 1998-09-16
NO984290L true NO984290L (en) 1998-10-27

Family

ID=27451427

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984290A NO984290L (en) 1996-03-20 1998-09-16 Pharmaceutically useful compounds

Country Status (19)

Country Link
EP (1) EP0888347A1 (en)
JP (1) JP2000506884A (en)
KR (1) KR20000064716A (en)
CN (1) CN1218472A (en)
AR (1) AR006520A1 (en)
AU (1) AU712141B2 (en)
BR (1) BR9708103A (en)
CA (1) CA2247814A1 (en)
CZ (1) CZ297798A3 (en)
EE (1) EE9800298A (en)
ID (1) ID16283A (en)
IL (1) IL126271A0 (en)
IS (1) IS4848A (en)
NO (1) NO984290L (en)
NZ (1) NZ331614A (en)
PL (1) PL328921A1 (en)
SK (1) SK118798A3 (en)
TR (1) TR199801861T2 (en)
WO (1) WO1997034893A1 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10110749A1 (en) * 2001-03-07 2002-09-12 Bayer Ag Substituted aminodicarboxylic acid derivatives
JP2003002863A (en) * 2001-06-25 2003-01-08 Nippon Soda Co Ltd Method for producing benzoic acids and novel compounds
US6642249B2 (en) 2001-07-04 2003-11-04 Active Biotech Ab Immunomodulating compounds
SE0102404D0 (en) * 2001-07-04 2001-07-04 Active Biotech Ab Novel immunomodulating compounds
DE10229762A1 (en) * 2002-07-03 2004-01-22 Aventis Pharma Deutschland Gmbh Pyrazoloisoquinoline derivatives for the inhibition of NFkappaB-inducing kinase
JP2006509047A (en) 2002-11-22 2006-03-16 アクティブ バイオテック アクチボラーグ Pyrazoloquinolines with immunomodulatory activity
EP1572689B1 (en) * 2002-12-16 2009-03-11 Active Biotech AB Tetracyclic immunomodulatory compounds
KR101133959B1 (en) * 2003-03-14 2012-04-09 메디진 아게 Immunomodulating heterocyclic compounds
GB0325644D0 (en) 2003-11-04 2003-12-10 Avidex Ltd Immuno ihibitory pyrazolone compounds
EP1692111A2 (en) 2003-12-12 2006-08-23 Wyeth, A Corporation of the State of Delaware Quinolines useful in treating cardiovascular disease
FR2870239B1 (en) * 2004-05-11 2006-06-16 Sanofi Synthelabo DERIVATIVES OF 2H- OR 3H-BENZO [E] INDAZOL-1-YLE CARBAMATE, THEIR PREPARATION AND THEIR THERAPEUTIC USE.
GB0411770D0 (en) * 2004-05-26 2004-06-30 Avidex Ltd Immuno inhibitory heterocyclic compouds
MX2007001238A (en) * 2004-08-09 2007-04-17 Avidex Ltd Immunomodulating oxopyrrazolocinnolines as cd80 inhibitors.
RS20090208A (en) 2006-10-31 2010-06-30 Pfizer Products Inc. Pyrazoline compounds as mineralocorticoid receptor antagonists
CN102372710A (en) 2010-08-18 2012-03-14 山东轩竹医药科技有限公司 Fused cyclic compound being taken as mineral corticoid recept antagonist
CN103347873A (en) 2011-02-09 2013-10-09 日产化学工业株式会社 Pyrazole derivative and pest control agent
DK3846904T3 (en) * 2018-09-07 2023-08-21 Merck Patent Gmbh 5-MORPHOLIN-4-YL-PYRAZOLO[4,3-B]PYRIDINE DERIVATIVES
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
CA3188639A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
EP4298099A1 (en) 2021-02-25 2024-01-03 Incyte Corporation Spirocyclic lactams as jak2 v617f inhibitors
JP2025509672A (en) 2022-03-17 2025-04-11 インサイト・コーポレイション Tricyclic urea compounds as JAK2 V617F inhibitors
CN119638634B (en) * 2023-09-18 2026-01-30 上海赛默罗生物科技有限公司 2-oxo-coral compounds, their preparation methods and uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524146A (en) * 1982-12-08 1985-06-18 Ciba-Geigy Corporation Certain -2-heterocycle substituted pyrazoloquinolines
JPS61112075A (en) * 1984-11-05 1986-05-30 Shionogi & Co Ltd Thienylpyrazoloquinoline derivative
SE8903564D0 (en) * 1989-10-26 1989-10-26 Pharmacia Ab NEW USE CONDENSED QUINOLINE COMPOUND
JPH05194515A (en) * 1991-07-31 1993-08-03 Kyowa Hakko Kogyo Co Ltd Condensed naphthyridine derivative

Also Published As

Publication number Publication date
CA2247814A1 (en) 1997-09-25
ID16283A (en) 1997-09-18
CN1218472A (en) 1999-06-02
JP2000506884A (en) 2000-06-06
KR20000064716A (en) 2000-11-06
EP0888347A1 (en) 1999-01-07
PL328921A1 (en) 1999-03-01
EE9800298A (en) 1999-02-15
CZ297798A3 (en) 1999-03-17
AU712141B2 (en) 1999-10-28
AU2186797A (en) 1997-10-10
TR199801861T2 (en) 1998-12-21
WO1997034893A1 (en) 1997-09-25
IS4848A (en) 1998-09-16
IL126271A0 (en) 1999-05-09
BR9708103A (en) 1999-07-27
NZ331614A (en) 2000-07-28
AR006520A1 (en) 1999-09-08
NO984290D0 (en) 1998-09-16
SK118798A3 (en) 1999-03-12

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