NO972475L - Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav - Google Patents
Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse deravInfo
- Publication number
- NO972475L NO972475L NO972475A NO972475A NO972475L NO 972475 L NO972475 L NO 972475L NO 972475 A NO972475 A NO 972475A NO 972475 A NO972475 A NO 972475A NO 972475 L NO972475 L NO 972475L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- formulation
- new antithrombotic
- antithrombotic formulation
- new
- Prior art date
Links
- 230000002785 anti-thrombosis Effects 0.000 title abstract 2
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 208000005189 Embolism Diseases 0.000 abstract 1
- 101000712605 Theromyzon tessulatum Theromin Proteins 0.000 abstract 1
- 229940122388 Thrombin inhibitor Drugs 0.000 abstract 1
- 208000001435 Thromboembolism Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 239000003868 thrombin inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Ny farmasfaytisk formulering omfattende trombininhibitoren H00C-CH2-(R)-Cgl-Aze- Pab i kombinasjon med ett eller flere absorpsjonsforsterkende midler, en fremgangsmåte for fremstilling av en slik farmasøytisk formulering, anvendelse av en slik formulering i behandlingen av tromboembolisme samt en metode for behandling av en pasient som har behov for antitrombotisk behandling og tromboembolisme ved bruk av nevnte formulering.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9404196A SE9404196D0 (sv) | 1994-12-02 | 1994-12-02 | New antithrombotic formulation |
| PCT/SE1995/001425 WO1996016671A1 (en) | 1994-12-02 | 1995-11-29 | New antithrombotic formulation, process for its manufacturing, and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO972475L true NO972475L (no) | 1997-05-30 |
| NO972475D0 NO972475D0 (no) | 1997-05-30 |
Family
ID=20396207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972475A NO972475D0 (no) | 1994-12-02 | 1997-05-30 | Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5795896A (no) |
| EP (1) | EP0799052B1 (no) |
| JP (1) | JPH10513438A (no) |
| CN (1) | CN1168635A (no) |
| AR (1) | AR002254A1 (no) |
| AT (1) | ATE208628T1 (no) |
| AU (1) | AU689994B2 (no) |
| BR (1) | BR9509853A (no) |
| CA (1) | CA2206459A1 (no) |
| CZ (1) | CZ147097A3 (no) |
| DE (1) | DE69523943T2 (no) |
| DK (1) | DK0799052T3 (no) |
| EE (1) | EE03338B1 (no) |
| ES (1) | ES2168395T3 (no) |
| FI (1) | FI972332A7 (no) |
| HU (1) | HU216631B (no) |
| IL (1) | IL116153A (no) |
| IS (1) | IS4483A (no) |
| NO (1) | NO972475D0 (no) |
| NZ (1) | NZ297118A (no) |
| PL (1) | PL320692A1 (no) |
| PT (1) | PT799052E (no) |
| SE (1) | SE9404196D0 (no) |
| SK (1) | SK61797A3 (no) |
| TR (1) | TR199501517A2 (no) |
| WO (1) | WO1996016671A1 (no) |
| ZA (1) | ZA9510242B (no) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6984627B1 (en) * | 1993-06-03 | 2006-01-10 | Astrazeneca Ab | Peptide derivatives |
| SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
| GB9526273D0 (en) * | 1995-12-21 | 1996-02-21 | Astra Ab | New prodrugs |
| AR005245A1 (es) | 1995-12-21 | 1999-04-28 | Astrazeneca Ab | Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion |
| SE9602145D0 (sv) * | 1996-05-31 | 1996-05-31 | Astra Ab | New improved formulation for treatment of thromboembolism |
| US6423334B1 (en) * | 1997-10-01 | 2002-07-23 | Elan Corporation, Plc | Composition and method for enhancing transport across gastrointestinal tract cell layers |
| AR023510A1 (es) * | 1999-04-21 | 2002-09-04 | Astrazeneca Ab | Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina. |
| AR023819A1 (es) * | 1999-05-03 | 2002-09-04 | Astrazeneca Ab | FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION |
| SE9902550D0 (sv) * | 1999-07-02 | 1999-07-02 | Astra Ab | New crystalline forms |
| SE9904377D0 (sv) * | 1999-12-01 | 1999-12-01 | Astra Pharma Prod | Pharmaceutical combinations |
| US6462021B1 (en) | 2000-11-06 | 2002-10-08 | Astrazeneca Ab | Use of low molecular weight thrombin inhibitor |
| SE0101932D0 (sv) * | 2001-05-31 | 2001-05-31 | Astrazeneca Ab | Pharmaceutical combinations |
| US6884768B2 (en) | 2001-06-14 | 2005-04-26 | Otsuka Pharmaceutical Co., Ltd. | Medicinal compositions |
| SE0103590D0 (sv) * | 2001-10-26 | 2001-10-26 | Astrazeneca Ab | New Combination |
| SE0203349D0 (sv) * | 2002-11-12 | 2002-11-12 | Astrazeneca Ab | New use |
| DK1569912T3 (en) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors. |
| US7345093B2 (en) * | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
| US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
| US20060046962A1 (en) * | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
| US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| RU2354647C2 (ru) | 2007-06-28 | 2009-05-10 | Общество С Ограниченной Ответственностью "Бионика" | Новые соединения, обладающие функцией ингибиторов тромбина, и фармацевтические композиции на их основе |
| EP2271347B1 (en) | 2008-03-28 | 2016-05-11 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
| US8541360B2 (en) * | 2008-11-19 | 2013-09-24 | Ben Venue Laboratories, Inc. | Parenteral formulations comprising sugar-based esters and ethers |
| US8440631B2 (en) * | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US20100215730A1 (en) * | 2009-02-20 | 2010-08-26 | Intrepid Therapeutics, Inc. | Compositions for Nasal Administration of Phenothiazines |
| US20110070294A1 (en) * | 2009-09-23 | 2011-03-24 | Javeri Indu | Methods for the Administration of Drugs Using Liposomes |
| US20110070293A1 (en) * | 2009-09-23 | 2011-03-24 | Javeri Indu | Methods for the Preparation of Liposomes Comprising Docetaxel |
| US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
| CN103796656A (zh) | 2011-06-14 | 2014-05-14 | 哈尔生物药投资有限责任公司 | 苯二氮卓的投与 |
| EA202091615A1 (ru) | 2018-12-21 | 2021-03-05 | Аегис Терапьютикс, Ллс | Интраназальные составы на основе эпинефрина и способы лечения заболевания |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU178398B (en) * | 1979-06-12 | 1982-04-28 | Gyogyszerkutato Intezet | Process for producing new agmatine derivatives of activity against haemagglutination |
| US4568636A (en) * | 1981-03-25 | 1986-02-04 | Pentapharm Ag | Tripeptide derivatives |
| US4395401A (en) * | 1981-09-09 | 1983-07-26 | Smithkline Beckman Corporation | Renally active dipeptides |
| HU192646B (en) * | 1984-12-21 | 1987-06-29 | Gyogyszerkutato Intezet | Process for preparing new n-alkyl-peptide aldehydes |
| ZA86746B (en) * | 1985-02-04 | 1986-09-24 | Merrell Dow Pharma | Novel peptidase inhibitors |
| DE3505555A1 (de) * | 1985-02-18 | 1986-09-11 | Behringwerke Ag, 3550 Marburg | Neue oligopeptidylargininolderivate und deren homologe, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel |
| PT84170B (pt) * | 1986-01-24 | 1989-03-30 | Sanofi Sa | Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas |
| DE3606480A1 (de) * | 1986-02-28 | 1987-09-03 | Behringwerke Ag | Oligopeptidylnitrilderivate, diese enthaltende mittel, verfahren zu ihrer herstellung und ihre verwendung |
| US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| EP0362002B1 (en) * | 1988-09-01 | 1995-07-26 | Merrell Dow Pharmaceuticals Inc. | HIV protease inhibitors |
| ZA897514B (en) * | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
| US5053392A (en) * | 1989-12-01 | 1991-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Novel arginine, glycine, aspartic acid derivatives as platelet-aggregation inhibitors |
| US5037819A (en) * | 1990-06-04 | 1991-08-06 | Bristol-Myers Squibb Company | Azetidin-2-one derivatives as serine protease inhibitors |
| US5110812A (en) * | 1990-06-04 | 1992-05-05 | Bristol-Myers Squibb Co. | Azetidin-2-one derivatives as serine protease inhibitors |
| TW201303B (no) * | 1990-07-05 | 1993-03-01 | Hoffmann La Roche | |
| GB9017694D0 (en) * | 1990-08-13 | 1990-09-26 | Sandoz Ltd | Improvements in or relating to organic chemistry |
| GB9019558D0 (en) * | 1990-09-07 | 1990-10-24 | Szelke Michael | Enzyme inhibitors |
| IL99527A (en) * | 1990-09-28 | 1997-08-14 | Lilly Co Eli | Tripeptide antithrombotic agents |
| GB9024129D0 (en) * | 1990-11-06 | 1990-12-19 | Thrombosis Research Trust | Inhibitors and substrates of thrombin |
| CA2073776A1 (en) * | 1990-11-15 | 1992-05-16 | Joerg Stuerzebecher | Meta-substituted phenyl alanine derivatives |
| DE4115468A1 (de) * | 1991-05-11 | 1992-11-12 | Behringwerke Ag | Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien |
| SE9102462D0 (sv) * | 1991-08-28 | 1991-08-28 | Astra Ab | New isosteric peptides |
| ZA928581B (en) * | 1991-11-12 | 1994-05-06 | Lilly Co Eli | Antithrombotic agents |
| SE9103612D0 (sv) * | 1991-12-04 | 1991-12-04 | Astra Ab | New peptide derivatives |
| SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
-
1994
- 1994-12-02 SE SE9404196A patent/SE9404196D0/xx unknown
-
1995
- 1995-11-27 IL IL11615395A patent/IL116153A/xx not_active IP Right Cessation
- 1995-11-29 DK DK95940490T patent/DK0799052T3/da active
- 1995-11-29 FI FI972332A patent/FI972332A7/fi unknown
- 1995-11-29 DE DE69523943T patent/DE69523943T2/de not_active Expired - Fee Related
- 1995-11-29 JP JP8518675A patent/JPH10513438A/ja not_active Ceased
- 1995-11-29 AT AT95940490T patent/ATE208628T1/de not_active IP Right Cessation
- 1995-11-29 EP EP95940490A patent/EP0799052B1/en not_active Expired - Lifetime
- 1995-11-29 NZ NZ297118A patent/NZ297118A/xx unknown
- 1995-11-29 SK SK617-97A patent/SK61797A3/sk unknown
- 1995-11-29 WO PCT/SE1995/001425 patent/WO1996016671A1/en not_active Ceased
- 1995-11-29 BR BR9509853A patent/BR9509853A/pt not_active Application Discontinuation
- 1995-11-29 PT PT95940490T patent/PT799052E/pt unknown
- 1995-11-29 PL PL95320692A patent/PL320692A1/xx unknown
- 1995-11-29 CA CA002206459A patent/CA2206459A1/en not_active Abandoned
- 1995-11-29 HU HU9800503A patent/HU216631B/hu not_active IP Right Cessation
- 1995-11-29 EE EE9700121A patent/EE03338B1/xx unknown
- 1995-11-29 CZ CZ971470A patent/CZ147097A3/cs unknown
- 1995-11-29 ES ES95940490T patent/ES2168395T3/es not_active Expired - Lifetime
- 1995-11-29 AU AU41915/96A patent/AU689994B2/en not_active Ceased
- 1995-11-29 US US08/564,122 patent/US5795896A/en not_active Expired - Fee Related
- 1995-11-29 CN CN95196581A patent/CN1168635A/zh active Pending
- 1995-11-30 TR TR95/01517A patent/TR199501517A2/xx unknown
- 1995-11-30 AR ARP950100405A patent/AR002254A1/es not_active Application Discontinuation
- 1995-12-01 ZA ZA9510242A patent/ZA9510242B/xx unknown
-
1997
- 1997-05-16 IS IS4483A patent/IS4483A/is unknown
- 1997-05-30 NO NO972475A patent/NO972475D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE9404196D0 (sv) | 1994-12-02 |
| CN1168635A (zh) | 1997-12-24 |
| IL116153A0 (en) | 1996-01-31 |
| JPH10513438A (ja) | 1998-12-22 |
| ES2168395T3 (es) | 2002-06-16 |
| AR002254A1 (es) | 1998-03-11 |
| HUT77655A (hu) | 1998-07-28 |
| PT799052E (pt) | 2002-05-31 |
| EP0799052A1 (en) | 1997-10-08 |
| IS4483A (is) | 1997-05-16 |
| EP0799052B1 (en) | 2001-11-14 |
| ATE208628T1 (de) | 2001-11-15 |
| IL116153A (en) | 1999-11-30 |
| SK61797A3 (en) | 1998-03-04 |
| CA2206459A1 (en) | 1996-06-06 |
| NO972475D0 (no) | 1997-05-30 |
| PL320692A1 (en) | 1997-10-27 |
| TR199501517A2 (tr) | 1996-07-21 |
| DE69523943D1 (de) | 2001-12-20 |
| ZA9510242B (en) | 1996-06-03 |
| MX9703975A (es) | 1997-09-30 |
| FI972332A0 (fi) | 1997-06-02 |
| FI972332L (fi) | 1997-06-02 |
| CZ147097A3 (cs) | 1998-02-18 |
| WO1996016671A1 (en) | 1996-06-06 |
| DK0799052T3 (da) | 2002-02-25 |
| FI972332A7 (fi) | 1997-06-02 |
| HU216631B (hu) | 1999-07-28 |
| AU689994B2 (en) | 1998-04-09 |
| AU4191596A (en) | 1996-06-19 |
| BR9509853A (pt) | 1997-12-30 |
| US5795896A (en) | 1998-08-18 |
| EE03338B1 (et) | 2001-02-15 |
| DE69523943T2 (de) | 2002-06-27 |
| NZ297118A (en) | 1998-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |