[go: up one dir, main page]

NO972450L - Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav - Google Patents

Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav

Info

Publication number
NO972450L
NO972450L NO972450A NO972450A NO972450L NO 972450 L NO972450 L NO 972450L NO 972450 A NO972450 A NO 972450A NO 972450 A NO972450 A NO 972450A NO 972450 L NO972450 L NO 972450L
Authority
NO
Norway
Prior art keywords
phosphinyloxymethyl
thiadiazolidin
dioxides
substituted
preparations
Prior art date
Application number
NO972450A
Other languages
English (en)
Other versions
NO972450D0 (no
Inventor
John J Court
Ranjit C Desai
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of NO972450D0 publication Critical patent/NO972450D0/no
Publication of NO972450L publication Critical patent/NO972450L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539—Five-membered rings
    • C07F9/65392—Five-membered rings containing two nitrogen atoms
    • C07F9/65397—Five-membered rings containing two nitrogen atoms having the two nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

Substituerte 2-(fosfinyloksymetyl)-l,2,5-tiadiazolidin-3-on 1,1-dioksider, farmasøytiske preparater inneholdende slike forbindelser og metoder for behandling av degenerative sykdommer under anvendelse derav.
NO972450A 1994-12-02 1997-05-29 Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav NO972450L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/348,411 US5541168A (en) 1994-12-02 1994-12-02 Substituted 2-(phosphinyloxymethyl)-1,2,5-thiadiazolidin-3-one 1,1-dioxides and compositions and method of use thereof
PCT/US1995/015565 WO1996016970A1 (en) 1994-12-02 1995-11-30 Substituted 2-(phosphinyloxymethyl)-1,2,5-thiadiazolidin-3-one 1,1-dioxides and compositions and method of use thereof

Publications (2)

Publication Number Publication Date
NO972450D0 NO972450D0 (no) 1997-05-29
NO972450L true NO972450L (no) 1997-05-29

Family

ID=23367928

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972450A NO972450L (no) 1994-12-02 1997-05-29 Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav

Country Status (12)

Country Link
US (1) US5541168A (no)
EP (1) EP0794956A4 (no)
JP (1) JP2001520626A (no)
CN (1) CN1173179A (no)
AU (1) AU704233B2 (no)
CA (1) CA2205950A1 (no)
FI (1) FI972310L (no)
HU (1) HUT78043A (no)
MX (1) MX9704035A (no)
NO (1) NO972450L (no)
NZ (1) NZ297344A (no)
WO (1) WO1996016970A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420401B1 (en) * 1997-08-22 2002-07-16 Wichita State University 1,2,5, thiadiazolidin-3-one 1,1-dioxide derivatives
CO5261615A1 (es) 1999-12-01 2003-03-31 Agouron Pharma Compuestos, composiciones y metodos para estimular el crecimiento y elongacion de neuronas
US7432292B2 (en) * 2002-12-30 2008-10-07 Vertex Pharmaceuticals Incorporated Sulfhydantoins as phosphate isosteres
CN113372368B (zh) 2020-03-09 2022-04-12 苏州爱科百发生物医药技术有限公司 一种弹性蛋白酶抑制剂前药及其用途
EP4674840A1 (en) * 2023-02-28 2026-01-07 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Chemical coupling linker and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236917A (en) * 1989-05-04 1993-08-17 Sterling Winthrop Inc. Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
DE4141218A1 (de) * 1991-12-13 1993-06-17 Luitpold Werk Chem Pharm Thiadiazincarbonsaeureamidderivate, verfahren zu ihrer herstellung und arzneimittel
AU668694B2 (en) * 1991-12-19 1996-05-16 Sanofi-Synthelabo Saccharin derivative proteolytic enzyme inhibitors
US5378720A (en) * 1991-12-19 1995-01-03 Sterling Winthrop Inc. Saccharin derivative proteolytic enzyme inhibitors
US5296496A (en) * 1991-12-27 1994-03-22 Sterling Winthrop Inc. 2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
US5187173A (en) * 1991-12-27 1993-02-16 Sterling Winthrop Inc. 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof

Also Published As

Publication number Publication date
EP0794956A4 (en) 1998-02-11
JP2001520626A (ja) 2001-10-30
EP0794956A1 (en) 1997-09-17
CN1173179A (zh) 1998-02-11
FI972310A7 (fi) 1997-07-21
NZ297344A (en) 1998-11-25
WO1996016970A1 (en) 1996-06-06
AU704233B2 (en) 1999-04-15
HUT78043A (hu) 1999-07-28
AU4248596A (en) 1996-06-19
CA2205950A1 (en) 1996-06-06
NO972450D0 (no) 1997-05-29
MX9704035A (es) 1998-02-28
FI972310A0 (fi) 1997-05-30
US5541168A (en) 1996-07-30
FI972310L (fi) 1997-07-21

Similar Documents

Publication Publication Date Title
NO972451L (no) Heterosyklyloksy- og tiometyl-1,2,5-tiadiazolidin-3-on 1,1-dioksyder og preparater og fremgangsmåte for anvendelse derav
NO973479L (no) Substituerte heterosykliske forbindelser, fremgangsmåte for fremstilling og farmasöytiske blandinger inneholdende samme
NO972391L (no) 2-substituerte 1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metoder for anvendelse derav
UA26213C2 (uk) Засіб для профілактики та лікуваhhя остеопорозу та фармацевтичhа композиція hа їх осhові
NO306346B1 (no) N-substituerte azabicykloalkanderivater, anvendelse derav og farmasöytisk preparat
MY106315A (en) Pharmaceutical agents
MY103802A (en) 5-lipoxygenase inhibiting 4-(4-phenyl-1- piperazinyl) phenols.
DK0693285T3 (da) Farmaceutiske præparater, der indeholder et bisphosphonat og et antiresorberende middel til inhibering af knogletab
DE3478810D1 (en) Benzazocinone and benzazoninone derivatives, process for their preparation, pharmaceutical preparations containing these compounds, and their therapeutical use
GR900100326A (en) Saccharin derivatives useful as proteolytic enzyme inhibitors and preparation thereof
AU563650B2 (en) Pharmaceutical compositions of benzothiophene derivatives
FI945975L (fi) Haarautuneella aminoryhmällä substituoituja tiatsoleja, menetelmiä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
MA22495A1 (fr) Derives d'amidinophenylalanine, procede pour leur preparation et leur utilisation
NO972449L (no) Substituerte 2-arylkarbonyloksymetyl-1,2,5-tiadiazolidin-3-on-1,1-dioksidderivater og preparater og fremgangsmåte for anvendelse derav
KR950700310A (ko) 헤테로트리사이클릭 유도체, 그의 제조방법 및 그를 함유하는 약제학적 조성물(heterotricyclic derivatives, process for their preparation and pharmaceutical compositions containing them)
NO972450L (no) Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav
HUT77868A (hu) Imidazopiridin-azolidinonok, ezeket tartalmazó gyógyszerkészítmények, alkalmazásuk és eljárás előállításukra
NO972435L (no) 2-(2,3,5,6-tetrafluor-4-pyridyl)-1,2,5-tradiazolidin-3-on 1,1-dioksider og preparater og metoder for anvendelse derav
DE3578125D1 (de) Formulierung von entzuendungshemmenden arzneimitteln.
ATE328597T1 (de) Arzneimittel zur verminderung der effekte während oder nach der menopause und verfahren tur behandlung under verwendung derselben
DK130293D0 (da) Benzox(thi)azine derivatives, pharmaceutical compositions thereof, and method of treating therewith