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NO972211L - Sulfonamide-substituted chromanes, their preparation, their use as a drug or diagnostic, and drugs containing the chromanes - Google Patents

Sulfonamide-substituted chromanes, their preparation, their use as a drug or diagnostic, and drugs containing the chromanes

Info

Publication number
NO972211L
NO972211L NO972211A NO972211A NO972211L NO 972211 L NO972211 L NO 972211L NO 972211 A NO972211 A NO 972211A NO 972211 A NO972211 A NO 972211A NO 972211 L NO972211 L NO 972211L
Authority
NO
Norway
Prior art keywords
chromanes
preparation
sulfonamide
diagnostic
drug
Prior art date
Application number
NO972211A
Other languages
Norwegian (no)
Other versions
NO972211D0 (en
NO315556B1 (en
Inventor
Hans Jochen Lang
Uwe Gerlach
Joachim Brendel
Heinrich Christian Englert
Heinz Goegelein
Max Hropot
Helmut Bohn
Andreas Herling
Andreas Busch
Rainer Greger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19619614A external-priority patent/DE19619614A1/en
Priority claimed from DE1996139462 external-priority patent/DE19639462A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO972211D0 publication Critical patent/NO972211D0/en
Publication of NO972211L publication Critical patent/NO972211L/en
Publication of NO315556B1 publication Critical patent/NO315556B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Sal roiuunNI-subst.i tiicili: knunajii r mt -il IuiiikI ( lj og formel (Ia). iler K( A), K(U). K(C) og K(l) LI 1 K(8) har diverse betydninger, er fremragende egnet for frems LI 11 lrig av et nedlkainent for blokkering av IC^-kanalen som åpnes av cykllsk adenosinmoiiofosfat (cAMP), for fremstilling av et nedlkament for inhiber ing av mavesyresekresjonen;. Tor behandling av ulcere l maven og LntesLlnalområdet og særlig duodenum, for behandling av rcfluksoesofagiLL, ?or behandling av dlaré-sykdonmer, for Lerapl og prevensjon av alle typer aryUnler, inkludert ventrikulire og supraveritrikulære arytmler samt for kontroll av reentry-aryUnier og prevensjon av plutselig hjertedwl som fulge av kaiiinerfl Jiiiiier.Sal roiuunNI-subst.i tiicili: knunajii r mt -il IuiiikI (lj and formula (Ia). Iler K (A), K (U). K (C) and K (l) LI 1 K (8) have miscellaneous meaning, is excellently suitable for promoting LI 11 lrig of a down-blocking IC 1 channel opened by cyclic adenosine moiophosphate (cAMP), for the preparation of a down-block for inhibiting gastric acid secretion; especially the duodenum, for the treatment of rcfluxesophagyLL, or for the treatment of dlaré diseases, for Lerapl and contraception of all types of aryUnler, including ventricular and supraveritricular arrhythmias as well as for the control of reentry-aryUnier and the prevention of sudden cardiac diarrhea followed by Ji.

NO19972211A 1996-05-15 1997-05-14 Chromogens, their preparation and use, as well as medications containing the compounds NO315556B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619614A DE19619614A1 (en) 1996-05-15 1996-05-15 New sulphonamide derivatives of chroman
DE1996139462 DE19639462A1 (en) 1996-09-26 1996-09-26 New sulphonamide derivatives of chroman

Publications (3)

Publication Number Publication Date
NO972211D0 NO972211D0 (en) 1997-05-14
NO972211L true NO972211L (en) 1997-11-17
NO315556B1 NO315556B1 (en) 2003-09-22

Family

ID=26025736

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19972211A NO315556B1 (en) 1996-05-15 1997-05-14 Chromogens, their preparation and use, as well as medications containing the compounds

Country Status (23)

Country Link
EP (1) EP0807629B1 (en)
JP (1) JP4234798B2 (en)
KR (1) KR100547921B1 (en)
CN (1) CN1204134C (en)
AR (2) AR007115A1 (en)
AT (1) ATE260909T1 (en)
AU (1) AU711986B2 (en)
BR (1) BR9703161A (en)
CA (1) CA2205477A1 (en)
CZ (1) CZ149497A3 (en)
DE (1) DE59711352D1 (en)
DK (1) DK0807629T3 (en)
ES (1) ES2218617T3 (en)
HR (1) HRP970255B1 (en)
HU (1) HUP9700903A3 (en)
IL (1) IL120827A (en)
NO (1) NO315556B1 (en)
NZ (1) NZ314800A (en)
PL (1) PL191330B1 (en)
PT (1) PT807629E (en)
SK (1) SK283837B6 (en)
TR (1) TR199700369A2 (en)
TW (1) TW496866B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329200A (en) * 1996-12-16 1999-05-28 Hoechst Ag Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (en) * 1997-02-11 1998-08-13 Hoechst Ag Sulfonamide-substituted compounds, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
DE19706675A1 (en) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
EP0895994A3 (en) * 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulphonamide-substituted Pyranopyridines, process for their production and their use as a drug or diagnostics as well as medicaments containing them
DE19742509A1 (en) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and pharmaceutical preparations containing them
DE19742508A1 (en) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamide-substituted chromanes, processes for their preparation, their use as medicaments or diagnostic agents and pharmaceutical preparations containing them
DE19748469A1 (en) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as medicaments and pharmaceutical preparations containing them
JP2002523451A (en) 1998-09-01 2002-07-30 ブリストル−マイヤーズ スクイブ カンパニー Potassium channel inhibitors and methods
DE19858253A1 (en) * 1998-12-17 2000-06-21 Aventis Pharma Gmbh Use of KQt1 channel inhibitors for the manufacture of a medicament for the treatment of diseases caused by helminths and ectoparasites
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
UA91189C2 (en) * 2004-03-23 2010-07-12 Ниссан Кемикал Индастриз, Лтд. Tricyclic benzopyran compound as anti-arrhythmic agents
US7884109B2 (en) 2005-04-05 2011-02-08 Wyeth Llc Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
AR063142A1 (en) 2006-10-04 2008-12-30 Pharmacopeia Inc DERIVATIVES OF 2- (BENCIMIDAZOLIL) PURINE AND PURINONES 6-USEFUL SUBSTITUTES AS IMMUNOSUPPRESSORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
WO2008043019A1 (en) 2006-10-04 2008-04-10 Pharmacopeia, Inc 8-substituted 2-(benzimidazolyl) purine derivatives for immunosuppression
PL2426133T3 (en) * 2009-04-30 2016-04-29 Nissan Chemical Ind Ltd Novel crystal forms of tricyclic benzopyran compound and processes for producing same
TWI583677B (en) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 Coumarin derivative
CN103012380B (en) * 2013-01-10 2015-03-04 山东大学 Chroman compound, and preparation method and application thereof
JP6089055B2 (en) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 Pharmaceuticals containing coumarin derivatives
AR117169A1 (en) 2018-11-28 2021-07-14 Bayer Ag (TIO) PYRIDAZINE AMIDES AS FUNGICIDE COMPOUNDS
WO2021224220A1 (en) 2020-05-06 2021-11-11 Bayer Aktiengesellschaft Pyridine (thio)amides as fungicidal compounds
WO2021228734A1 (en) 2020-05-12 2021-11-18 Bayer Aktiengesellschaft Triazine and pyrimidine (thio)amides as fungicidal compounds
BR112022023550A2 (en) 2020-05-19 2023-01-03 Bayer Cropscience Ag AZABICYCLIC (THIO)AMIDES AS FUNGICIDAL COMPOUNDS
CN115697059A (en) 2020-05-27 2023-02-03 拜耳公司 active compound combination
EP4426677A1 (en) 2021-11-03 2024-09-11 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737195A1 (en) * 1987-11-03 1989-05-18 Bayer Ag CHROME DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS
FR2639349B1 (en) * 1988-11-23 1991-02-22 Sanofi Sa NOVEL CHROMANE DERIVATIVES ACTIVE IN THE CENTRAL NERVOUS SYSTEM, THEIR PREPARATION METHOD AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof

Also Published As

Publication number Publication date
DK0807629T3 (en) 2004-05-17
SK60397A3 (en) 1998-02-04
AU711986B2 (en) 1999-10-28
CZ149497A3 (en) 1997-12-17
HRP970255B1 (en) 2003-10-31
MX9703534A (en) 1997-11-29
JP4234798B2 (en) 2009-03-04
ATE260909T1 (en) 2004-03-15
TR199700369A2 (en) 1997-12-21
IL120827A (en) 2004-12-15
EP0807629B1 (en) 2004-03-03
AR010314A1 (en) 2000-06-07
HRP970255A2 (en) 1998-04-30
DE59711352D1 (en) 2004-04-08
TW496866B (en) 2002-08-01
NO972211D0 (en) 1997-05-14
AR007115A1 (en) 1999-10-13
HU9700903D0 (en) 1997-07-28
HUP9700903A3 (en) 1999-03-01
JPH1067772A (en) 1998-03-10
BR9703161A (en) 1998-09-29
CN1169429A (en) 1998-01-07
ES2218617T3 (en) 2004-11-16
NO315556B1 (en) 2003-09-22
PL191330B1 (en) 2006-04-28
EP0807629A1 (en) 1997-11-19
CA2205477A1 (en) 1997-11-15
KR19980024020A (en) 1998-07-06
AU2080697A (en) 1997-11-20
SK283837B6 (en) 2004-03-02
NZ314800A (en) 1999-02-25
KR100547921B1 (en) 2006-10-19
PL319995A1 (en) 1997-11-24
HUP9700903A2 (en) 1998-12-28
IL120827A0 (en) 1997-09-30
PT807629E (en) 2004-07-30
CN1204134C (en) 2005-06-01
HK1006640A1 (en) 1999-03-12

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