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NO971590D0 - Defektive adenovirus omfattende et terapeutisk gen og et immunobeskyttende gen - Google Patents

Defektive adenovirus omfattende et terapeutisk gen og et immunobeskyttende gen

Info

Publication number
NO971590D0
NO971590D0 NO971590A NO971590A NO971590D0 NO 971590 D0 NO971590 D0 NO 971590D0 NO 971590 A NO971590 A NO 971590A NO 971590 A NO971590 A NO 971590A NO 971590 D0 NO971590 D0 NO 971590D0
Authority
NO
Norway
Prior art keywords
gene
immunoprotective
defective adenoviruses
therapeutic
therapeutic gene
Prior art date
Application number
NO971590A
Other languages
English (en)
Norwegian (no)
Other versions
NO971590L (no
Inventor
Martin Lee
Michel Perricaudet
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO971590L publication Critical patent/NO971590L/no
Publication of NO971590D0 publication Critical patent/NO971590D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO971590A 1994-10-17 1997-04-07 Defektive adenovirus omfattende et terapeutisk gen og et immunobeskyttende gen NO971590D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9412346A FR2725726B1 (fr) 1994-10-17 1994-10-17 Vecteurs viraux et utilisation en therapie genique
PCT/FR1995/001326 WO1996012030A1 (fr) 1994-10-17 1995-10-11 Adenovirus defectifs comprenant un gene therapeutique et un gene immunoprotecteur

Publications (2)

Publication Number Publication Date
NO971590L NO971590L (no) 1997-04-07
NO971590D0 true NO971590D0 (no) 1997-04-07

Family

ID=9467911

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971590A NO971590D0 (no) 1994-10-17 1997-04-07 Defektive adenovirus omfattende et terapeutisk gen og et immunobeskyttende gen

Country Status (11)

Country Link
US (1) US6669942B2 (fr)
EP (1) EP0787198A1 (fr)
JP (1) JP3816952B2 (fr)
AU (1) AU712243B2 (fr)
CA (1) CA2201399A1 (fr)
FI (1) FI971613A7 (fr)
FR (1) FR2725726B1 (fr)
IL (1) IL115584A (fr)
NO (1) NO971590D0 (fr)
WO (1) WO1996012030A1 (fr)
ZA (1) ZA958686B (fr)

Families Citing this family (46)

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WO1994024267A1 (fr) * 1993-04-20 1994-10-27 Robinson, William, S. Methode et materiel de traitement de patients infectes par des agents infectieux intracellulaires
PT811073E (pt) * 1995-02-24 2007-03-30 Univ Pennsylvania Utilização de moduladores imunitários para preparar medicamentos que inibem as respostas imunitárias contra vírus recombinantes co-administrados
US6372208B1 (en) 1999-09-28 2002-04-16 The Trustees Of The University Of Pennsylvania Method of reducing an immune response to a recombinant virus
US6251957B1 (en) 1995-02-24 2001-06-26 Trustees Of The University Of Pennsylvania Method of reducing an immune response to a recombinant virus
US5872154A (en) * 1995-02-24 1999-02-16 The Trustees Of The University Of Pennsylvania Method of reducing an immune response to a recombinant adenovirus
US6281010B1 (en) 1995-06-05 2001-08-28 The Trustees Of The University Of Pennsylvania Adenovirus gene therapy vehicle and cell line
US6783980B2 (en) * 1995-06-15 2004-08-31 Crucell Holland B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
WO1997000326A1 (fr) * 1995-06-15 1997-01-03 Introgene B.V. Systemes d'empaquetage pour adenovirus recombinant chez l'homme, destine a la therapie genique
AUPN477695A0 (en) * 1995-08-14 1995-09-07 Commonwealth Scientific And Industrial Research Organisation Gene therapy
WO1998000166A1 (fr) * 1996-07-03 1998-01-08 Merial, Inc. ADENOVIRUS CANIN DE RECOMBINAISON (ACR) CONTENANT DE l'ADN EXOGENE
WO1998010087A1 (fr) * 1996-09-06 1998-03-12 Trustees Of The University Of Pennsylvania Vecteurs d'adenovirus de chimpanze
US6696423B1 (en) 1997-08-29 2004-02-24 Biogen, Inc. Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta
EP1025242A1 (fr) 1997-10-30 2000-08-09 Cornell Research Foundation, Inc. Procede inhibant la reponse immunitaire a un vecteur recombine
US20040043489A1 (en) * 1998-07-08 2004-03-04 Menzo Havenga Gene delivery vectors provided with a tissue tropism for dendritic cells and methods of use
US20030017138A1 (en) 1998-07-08 2003-01-23 Menzo Havenga Chimeric adenoviruses
US6929946B1 (en) 1998-11-20 2005-08-16 Crucell Holland B.V. Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
US6451319B1 (en) 1999-04-09 2002-09-17 Schering-Plough Veterinary Corporation Recombinant and mutant adenoviruses
WO2000061773A1 (fr) * 1999-04-09 2000-10-19 Schering-Plough Ltd. Adenovirus recombinants et mutants derives de l'adenovirus type 1 bovin
ATE364707T1 (de) * 1999-05-17 2007-07-15 Crucell Holland Bv Rekombinanter humaner adenovirus-serotyp 35
US6913922B1 (en) * 1999-05-18 2005-07-05 Crucell Holland B.V. Serotype of adenovirus and uses thereof
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
US20050232900A1 (en) * 1999-05-18 2005-10-20 Crucell Holland B.V. Serotype of adenovirus and uses thereof
GB9924981D0 (en) 1999-10-21 1999-12-22 Univ Manchester Gene therapy
CN1254719A (zh) * 1999-11-19 2000-05-31 钱其军 一种缺陷型腺病毒及其构建方法
EP1157999A1 (fr) * 2000-05-24 2001-11-28 Introgene B.V. Méthodes et moyens pour améliorer la transplantation de la peau en utilisant des vecteurs d'apport de genes munis d'un tropisme pour des fibroblastes primaires ainsi que d'autres utilisations de celles-ci
EP1322774A2 (fr) * 2000-09-20 2003-07-02 Crucell Holland B.V. Vecteurs de transfert de genes munis d'un tropisme tissulaire pour des cellules dendritiques
DE60138403D1 (de) 2000-09-26 2009-05-28 Crucell Holland Bv Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten
EP1203819A3 (fr) * 2000-10-06 2002-08-07 Transgene S.A. Vecteurs anti-inflammatoires
KR100432953B1 (ko) * 2001-09-01 2004-05-28 김주항 개선된 종양 살상 효과를 나타내는 재조합 아데노바이러스
CN100497639C (zh) 2002-04-25 2009-06-10 克鲁塞尔荷兰公司 生产腺病毒载体的手段和方法
ATE511401T1 (de) 2004-08-12 2011-06-15 Cedars Sinai Medical Center Kombinierte gentherapie zur behandlung makroskopischer glioma
WO2007086879A2 (fr) 2005-02-11 2007-08-02 University Of Southern California Procedes d’expression de proteines avec des ponts disulfure
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
AU2006311752A1 (en) * 2005-11-07 2007-05-18 Sidney Kimmel Cancer Center CD40 ligand fusion protein vaccine
WO2008095027A2 (fr) 2007-01-30 2008-08-07 Cedars-Sinai Medical Center Vecteur adenoviral comprenant une thymidine kinase de virus herpes simplex virus type 1 et un transgene pour augmenter l'expression du transgene
WO2010056901A2 (fr) 2008-11-13 2010-05-20 University Of Southern California Procédé d'expression de protéines avec ponts disulfure avec des rendements et une activité améliorés
US10837020B2 (en) * 2009-04-22 2020-11-17 Massachusetts Institute Of Technology Innate immune suppression enables repeated delivery of long RNA molecules
EP2421563B1 (fr) 2009-04-22 2017-04-12 Massachusetts Institute of Technology Suppression immunitaire innée permettant la distribution répétée de longues molécules d'arn
WO2012125791A2 (fr) * 2011-03-17 2012-09-20 Xiaoliu Zhang Incorporation du gène b18r pour stimuler l'effet antitumoral d'une virothérapie
US8445781B1 (en) 2011-11-15 2013-05-21 Nova D. Chasser Electrical receptacle cover having safety bracket for use with fragrance dispenser
TW201823465A (zh) 2016-09-20 2018-07-01 德商百靈佳殷格翰維美迪加股份有限公司 新穎豬流感疫苗
CN109715204B (zh) 2016-09-20 2023-08-22 勃林格殷格翰动物保健有限公司 新的ehv插入位点orf70
EA201990718A1 (ru) 2016-09-20 2019-10-31 Векторы аденовируса собачьих
DK3516064T3 (da) 2016-09-20 2025-07-14 Boehringer Ingelheim Vetmedica Gmbh Nye promotorer
US11839655B2 (en) 2017-09-01 2023-12-12 Microvax, Llc Combination cancer therapy
EP4221738A1 (fr) 2020-09-30 2023-08-09 Alma Bio Therapeutics Thérapie par acide nucléique pour la modulation différentielle de la microflore hôte

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1216710B1 (fr) * 1991-10-04 2006-04-05 Whitehead Institute For Biomedical Research Régulation de réponses immunitaires de l'organisme à l'aide de cytokines et d'antigènes
FR2688514A1 (fr) * 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
WO1994004196A1 (fr) * 1992-08-14 1994-03-03 Imperial Cancer Research Technology Limited Therapie de tumeurs
WO1994012649A2 (fr) * 1992-12-03 1994-06-09 Genzyme Corporation Therapie genique de la fibrose kystique
FR2705686B1 (fr) 1993-05-28 1995-08-18 Transgene Sa Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.

Also Published As

Publication number Publication date
NO971590L (no) 1997-04-07
US6669942B2 (en) 2003-12-30
US20020006395A1 (en) 2002-01-17
IL115584A (en) 2005-11-20
AU712243B2 (en) 1999-11-04
FI971613L (fi) 1997-04-16
AU3658495A (en) 1996-05-06
CA2201399A1 (fr) 1996-04-25
WO1996012030A1 (fr) 1996-04-25
JPH10507079A (ja) 1998-07-14
FI971613A0 (fi) 1997-04-16
IL115584A0 (en) 1996-01-19
FI971613A7 (fi) 1997-04-16
FR2725726B1 (fr) 1997-01-03
ZA958686B (en) 1996-05-22
JP3816952B2 (ja) 2006-08-30
EP0787198A1 (fr) 1997-08-06
FR2725726A1 (fr) 1996-04-19

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Legal Events

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