NO975872D0 - Formuleringer for kontrollert frigjöring av lite opplöselige medikamenter - Google Patents

Formuleringer for kontrollert frigjöring av lite opplöselige medikamenter

Info

Publication number: NO975872D0
Authority: NO; Norway
Prior art keywords: core; controlled release; formulation; poorly soluble; formulations
Prior art date: 1995-07-03

Application number

NO975872A

Other languages

English (en)

Other versions

NO975872L (no

Inventor

Maurice Joseph Clancy

Kenneth Ian Cumming

Michael Meyers

Original Assignee

Elan Corp Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-03

Filing date

1997-12-12

Publication date

1997-12-12

1997-12-12 Application filed by Elan Corp Plc filed Critical Elan Corp Plc

1997-12-12 Publication of NO975872D0 publication Critical patent/NO975872D0/no

1998-03-03 Publication of NO975872L publication Critical patent/NO975872L/no

Links

238000009472 formulation Methods 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 4
238000013270 controlled release Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 3
239000011248 coating agent Substances 0.000 abstract 2
238000000576 coating method Methods 0.000 abstract 2
CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
239000007962 solid dispersion Substances 0.000 abstract 2
ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
RZTAMFZIAATZDJ-HNNXBMFYSA-N 5-o-ethyl 3-o-methyl (4s)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)[C@@H]1C1=CC=CC(Cl)=C1Cl RZTAMFZIAATZDJ-HNNXBMFYSA-N 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
ZBBHBTPTTSWHBA-UHFFFAOYSA-N Nicardipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)CC=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZBBHBTPTTSWHBA-UHFFFAOYSA-N 0.000 abstract 1
RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 1
GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229960005132 cisapride Drugs 0.000 abstract 1
DCSUBABJRXZOMT-IRLDBZIGSA-N cisapride Chemical compound C([C@@H]([C@@H](CC1)NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)OC)N1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-IRLDBZIGSA-N 0.000 abstract 1
DCSUBABJRXZOMT-UHFFFAOYSA-N cisapride Natural products C1CC(NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)C(OC)CN1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-UHFFFAOYSA-N 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 abstract 1
229960001259 diclofenac Drugs 0.000 abstract 1
229960003580 felodipine Drugs 0.000 abstract 1
229960001680 ibuprofen Drugs 0.000 abstract 1
229960000905 indomethacin Drugs 0.000 abstract 1
239000008185 minitablet Substances 0.000 abstract 1
229960001783 nicardipine Drugs 0.000 abstract 1
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 1
229960001597 nifedipine Drugs 0.000 abstract 1
239000008188 pellet Substances 0.000 abstract 1
229960000502 poloxamer Drugs 0.000 abstract 1
229920001983 poloxamer Polymers 0.000 abstract 1
239000003826 tablet Substances 0.000 abstract 1
229960000351 terfenadine Drugs 0.000 abstract 1
229960000278 theophylline Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

Health & Medical Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO975872A 1995-07-03 1997-12-12 Formuleringer for kontrollert frigjöring av lite opplöselige medikamenter NO975872L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IE950492A IE80467B1 (en)	1995-07-03	1995-07-03	Controlled release formulations for poorly soluble drugs
US89795P	1995-07-06	1995-07-06
PCT/IE1996/000039 WO1997002017A1 (en)	1995-07-03	1996-07-01	Controlled release formulations for poorly soluble drugs

Publications (2)

Publication Number	Publication Date
NO975872D0 true NO975872D0 (no)	1997-12-12
NO975872L NO975872L (no)	1998-03-03

Family

ID=26319833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO975872A NO975872L (no)	1995-07-03	1997-12-12	Formuleringer for kontrollert frigjöring av lite opplöselige medikamenter

Country Status (20)

Country	Link
EP (1)	EP0836475B1 (no)
JP (1)	JPH11508587A (no)
KR (1)	KR19990028693A (no)
AT (1)	ATE208192T1 (no)
AU (1)	AU700654B2 (no)
BG (1)	BG102228A (no)
BR (1)	BR9609663A (no)
CA (1)	CA2226008A1 (no)
CZ (1)	CZ413497A3 (no)
DE (1)	DE69616795T2 (no)
HU (1)	HUP9900231A2 (no)
IE (1)	IE80467B1 (no)
IL (1)	IL122663A0 (no)
NO (1)	NO975872L (no)
NZ (1)	NZ311145A (no)
PL (1)	PL324402A1 (no)
SK (1)	SK175997A3 (no)
TW (1)	TW426528B (no)
WO (1)	WO1997002017A1 (no)
ZA (1)	ZA965609B (no)

Families Citing this family (55)

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IT1283029B1 (it) *	1996-05-17	1998-04-03	Resa Farma	Composizioni farmaceutiche a base di diclofenac
BE1009856A5 (fr) *	1995-07-14	1997-10-07	Sandoz Sa	Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
US6126970A (en) *	1995-12-01	2000-10-03	Janssen Pharmaceutica N.V.	Cisapride sustained release
CA2275604A1 (en) *	1997-01-03	1998-07-09	Kenneth Iain Cumming	Sustained release cisapride mini-tablet formulation
DE19710009A1 (de) *	1997-03-12	1998-09-24	Knoll Ag	Mehrphasige wirkstoffhaltige Zubereitungsformen
US6312724B1 (en)	1997-04-04	2001-11-06	Isa Odidi	Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
NZ328751A (en) *	1997-09-16	1999-01-28	Bernard Charles Sherman	Solid medicament containing an anionic surfactant and cyclosporin
KR20000069356A (ko) *	1997-10-07	2000-11-25	리차드 디. 슈미트	급속방출식 약물전달 제형
US6013280A (en) *	1997-10-07	2000-01-11	Fuisz Technologies Ltd.	Immediate release dosage forms containing microspheres
NZ333474A (en)	1998-01-02	1999-06-29	Mcneil Ppc Inc	A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IE980115A1 (en) *	1998-02-16	2000-02-09	Biovail Internat Ltd	Solubilizing delivery systems and method of manufacture
US6787157B1 (en)	1998-03-10	2004-09-07	Abbott Laboratories	Multiphase active ingredient-containing formulations
CA2301042A1 (en) *	1998-06-11	1999-12-16	Em Industries, Inc.	Micro-osmotic controlled drug delivery systems
TW407058B (en) *	1998-07-17	2000-10-01	Dev Center Biotechnology	Oral cisapride dosage forms with an extended duration
IE981008A1 (en) *	1998-12-02	2000-06-14	Fuisz Internat Ltd	Microparticles Containing Water Insoluble Active Agents
ATE404178T1 (de) *	1999-02-10	2008-08-15	Pfizer Prod Inc	Vorrichtung mit matrixgesteuerter wirkstofffreisetzung
US6706283B1 (en)	1999-02-10	2004-03-16	Pfizer Inc	Controlled release by extrusion of solid amorphous dispersions of drugs
EP1064938A1 (en) *	1999-06-28	2001-01-03	Sanofi-Synthelabo	Pharmaceutical dosage forms for controlled release producing at least a timed pulse
SE9902742D0 (sv) *	1999-07-20	1999-07-20	Astra Ab	New pharmaceutical formultion
KR100379299B1 (ko) *	2000-01-15	2003-04-10	주식회사 중외제약	펠로디핀의 가용화 방법 및 방출제어형 제제
KR20040100835A (ko)	2001-02-15	2004-12-02	킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨	안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법
EP1390063B1 (en) *	2001-05-03	2004-11-17	F. Hoffmann-La Roche Ag	Pharmaceutical dosage form of amorphous nelfinavir mesylate
AR033711A1 (es) *	2001-05-09	2004-01-07	Novartis Ag	Composiciones farmaceuticas
US7101569B2 (en)	2001-08-14	2006-09-05	Franz G Andrew	Methods of administering levothyroxine pharmaceutical compositions
TWI252111B (en) *	2001-12-14	2006-04-01	Solvay Pharm Gmbh	Matrix film tablet with controlled release of a natural mixture of conjugated estrogens
US20050232995A1 (en)	2002-07-29	2005-10-20	Yam Nyomi V	Methods and dosage forms for controlled delivery of paliperidone and risperidone
KR20040011248A (ko) *	2002-07-30	2004-02-05	환인제약 주식회사	암로디핀의 고체분산체와 그 제조방법 및 그를 포함하는약학적 조성물
WO2004050068A1 (en)	2002-11-29	2004-06-17	Janssen Pharmaceutica N.V.	Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
WO2004066981A1 (en) *	2003-01-29	2004-08-12	Sun Pharmaceutical Industries Limited	Oral controlled release pharmaceutical composition containing metaxalone as active agent
WO2004069180A2 (en)	2003-01-31	2004-08-19	Smithkline Beecham Corporation	Solid dispersion compositions
IE20040202A1 (en) *	2003-03-28	2004-10-06	Sigmoid Biotechnologies Ltd	Solid oral dosage form containing seamless microcapsules
EP1682092A2 (en) *	2003-11-13	2006-07-26	Alza Corporation	Melt blend dispersions comprising a low water solubility drug and an ethylene oxide-propylene oxide block copolymer
WO2005065653A1 (en) *	2003-12-19	2005-07-21	E.I. Du Pont De Nemours And Company	Intimate coating of ibuprofen with poloxamers to enhance aqueous dissolution
US8974823B2 (en)	2003-12-31	2015-03-10	Bend Research, Inc.	Solid compositions of low-solubility drugs and poloxamers
KR100598326B1 (ko)	2004-04-10	2006-07-10	한미약품 주식회사	ＨＭＧ-ＣｏＡ 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
US20080292702A1 (en) *	2005-12-16	2008-11-27	Hanmi Pharm. Co. Ltd.	Solid Dispersion Comprising An Active Ingredient Having A Low Melting Point And Tablet For Oral Administration Comprising Same
CA2660086C (en)	2006-08-16	2014-09-16	Novartis Ag	Method of making solid dispersions of highly crystalline therapeutic compounds
WO2008120131A2 (en) *	2007-03-30	2008-10-09	Wockhardt Research Centre	Pharmaceutical compositions of diclofenac and misoprostol
CA2683415C (en)	2007-04-04	2020-12-08	Sigmoid Pharma Limited	An oral pharmaceutical composition
WO2008132707A1 (en)	2007-04-26	2008-11-06	Sigmoid Pharma Limited	Manufacture of multiple minicapsules
CN106727424A (zh)	2009-04-24	2017-05-31	伊休蒂卡有限公司	双氯芬酸的新剂型
JP5640079B2 (ja)	2009-05-18	2014-12-10	シグモイド・ファーマ・リミテッドＳｉｇｍｏｉｄＰｈａｒｍａＬｉｍｉｔｅｄ	油滴含有組成物
BR112012002963A2 (pt)	2009-08-12	2017-10-24	Sigmoid Pharma Ltd	composições imunomoduladoras compreendendo uma matriz de polímero e uma fase oleosa
FR2967577B1 (fr) *	2010-11-18	2013-07-12	Advicenne Pharma	Composition pharmaceutique comprenant du sel de bicarbonate, et son utilisation comme medicament
FR2967576B1 (fr) *	2010-11-18	2013-07-12	Advicenne Pharma	Composition pharmaceutique comprenant du sel precurseur du cycle de krebs, en particulier du sel de citrate, et son utilisation comme medicament
GB201020032D0 (en)	2010-11-25	2011-01-12	Sigmoid Pharma Ltd	Composition
DE102012105512A1 (de) *	2012-06-25	2014-04-24	Hennig Arzneimittel Gmbh & Co. Kg	Arzneiform zur verlängerten Freisetzung von Wirkstoffen
GB201212010D0 (en)	2012-07-05	2012-08-22	Sigmoid Pharma Ltd	Formulations
CN102784128B (zh) *	2012-07-31	2015-01-07	北京协和药厂	一种非洛地平缓释制剂及其制备方法
GB201319791D0 (en)	2013-11-08	2013-12-25	Sigmoid Pharma Ltd	Formulations
US9526734B2 (en)	2014-06-09	2016-12-27	Iceutica Pty Ltd.	Formulation of meloxicam
EA036036B1 (ru)	2014-11-07	2020-09-16	Сигмойд Фарма Лимитед	Композиции, содержащие циклоспорин
CN112118830B (zh) *	2018-05-14	2023-11-10	比利时胶囊公司	高活性剂载量的固体剂型
CN113350309B (zh) *	2021-08-09	2021-11-12	北京五和博澳药业股份有限公司	一种难溶性药物渗透泵控释片剂及其制备方法
WO2025253272A1 (en) *	2024-06-05	2025-12-11	Chiaphua Industries Ltd.	Quick,self-dissolving,foamable antimicrobial tablet and method of preparation thereof

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EP0317780B1 (en) *	1987-11-25	1992-05-20	American Cyanamid Company	Sustained (controlled) release delivery system for substituted dihydropyridine calcium channel blockers

1995
- 1995-07-03 IE IE950492A patent/IE80467B1/en not_active IP Right Cessation
1996
- 1996-07-01 SK SK1759-97A patent/SK175997A3/sk unknown
- 1996-07-01 WO PCT/IE1996/000039 patent/WO1997002017A1/en not_active Ceased
- 1996-07-01 AU AU62394/96A patent/AU700654B2/en not_active Ceased
- 1996-07-01 NZ NZ311145A patent/NZ311145A/xx unknown
- 1996-07-01 KR KR1019970710016A patent/KR19990028693A/ko not_active Ceased
- 1996-07-01 IL IL12266396A patent/IL122663A0/xx unknown
- 1996-07-01 PL PL96324402A patent/PL324402A1/xx unknown
- 1996-07-01 CA CA002226008A patent/CA2226008A1/en not_active Abandoned
- 1996-07-01 BR BR9609663A patent/BR9609663A/pt not_active Application Discontinuation
- 1996-07-01 JP JP9504959A patent/JPH11508587A/ja active Pending
- 1996-07-01 AT AT96921053T patent/ATE208192T1/de active
- 1996-07-01 EP EP96921053A patent/EP0836475B1/en not_active Expired - Lifetime
- 1996-07-01 DE DE69616795T patent/DE69616795T2/de not_active Expired - Fee Related
- 1996-07-01 HU HU9900231A patent/HUP9900231A2/hu unknown
- 1996-07-01 CZ CZ974134A patent/CZ413497A3/cs unknown
- 1996-07-02 ZA ZA965609A patent/ZA965609B/xx unknown
- 1996-08-28 TW TW085110466A patent/TW426528B/zh not_active IP Right Cessation
1997
- 1997-12-12 NO NO975872A patent/NO975872L/no not_active Application Discontinuation
1998
- 1998-02-02 BG BG102228A patent/BG102228A/xx unknown

Also Published As

Publication number	Publication date
WO1997002017A1 (en)	1997-01-23
SK175997A3 (en)	1998-06-03
NZ311145A (en)	1999-06-29
NO975872L (no)	1998-03-03
CZ413497A3 (cs)	1998-04-15
TW426528B (en)	2001-03-21
DE69616795D1 (de)	2001-12-13
ZA965609B (en)	1997-01-27
JPH11508587A (ja)	1999-07-27
BG102228A (en)	1998-10-30
BR9609663A (pt)	1999-05-18
MX9710413A (es)	1998-07-31
ATE208192T1 (de)	2001-11-15
AU6239496A (en)	1997-02-05
IL122663A0 (en)	1998-08-16
IE80467B1 (en)	1998-07-29
KR19990028693A (ko)	1999-04-15
AU700654B2 (en)	1999-01-14
PL324402A1 (en)	1998-05-25
DE69616795T2 (de)	2002-08-08
EP0836475B1 (en)	2001-11-07
EP0836475A1 (en)	1998-04-22
CA2226008A1 (en)	1997-01-23
HUP9900231A2 (hu)	1999-06-28

Publication	Publication Date	Title
NO975872D0 (no)	1997-12-12	Formuleringer for kontrollert frigjöring av lite opplöselige medikamenter
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