[go: up one dir, main page]

NO974150L - 6-arylpyrazolo[3,4-d]pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav - Google Patents

6-arylpyrazolo[3,4-d]pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav

Info

Publication number
NO974150L
NO974150L NO974150A NO974150A NO974150L NO 974150 L NO974150 L NO 974150L NO 974150 A NO974150 A NO 974150A NO 974150 A NO974150 A NO 974150A NO 974150 L NO974150 L NO 974150L
Authority
NO
Norway
Prior art keywords
pyrimidin
ones
methods
arylpyrazolo
preparations
Prior art date
Application number
NO974150A
Other languages
English (en)
Other versions
NO974150D0 (no
Inventor
Edward R Bacon
Baldev Singh
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of NO974150D0 publication Critical patent/NO974150D0/no
Publication of NO974150L publication Critical patent/NO974150L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

6-ar>'lpyrazolo[3,4-d]-pyrimidin-4-oner, farmasøytiske preparater inneholdende disse og metoder for å bevirke c-GMP-fosfodiesteraseinhibering, behandlet av hjertesvikt og/eller hypertensjon.
NO974150A 1995-03-10 1997-09-09 6-arylpyrazolo[3,4-d]pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav NO974150L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40226195A 1995-03-10 1995-03-10
PCT/US1996/003100 WO1996028448A1 (en) 1995-03-10 1996-03-05 6-ARYL PYRAZOLO[3,4-d]PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF

Publications (2)

Publication Number Publication Date
NO974150D0 NO974150D0 (no) 1997-09-09
NO974150L true NO974150L (no) 1997-11-07

Family

ID=23591191

Family Applications (1)

Application Number Title Priority Date Filing Date
NO974150A NO974150L (no) 1995-03-10 1997-09-09 6-arylpyrazolo[3,4-d]pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav

Country Status (13)

Country Link
US (2) US5736548A (no)
EP (1) EP0813534A4 (no)
JP (1) JPH11501926A (no)
KR (1) KR19980702892A (no)
AU (1) AU708809B2 (no)
CA (1) CA2211729A1 (no)
CZ (1) CZ280697A3 (no)
HU (1) HUP9801394A3 (no)
NO (1) NO974150L (no)
NZ (1) NZ303886A (no)
PL (1) PL322452A1 (no)
WO (1) WO1996028448A1 (no)
ZA (1) ZA961948B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664261B2 (en) 1996-02-07 2003-12-16 Neurocrine Biosciences, Inc. Pyrazolopyrimidines as CRF receptor antagonists
DE19709877A1 (de) * 1997-03-11 1998-09-17 Bayer Ag 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate
KR100390612B1 (ko) 1997-04-25 2003-07-07 화이자 인코포레이티드 타입 5 시클릭 구아노신 3',5'-모노포스페이트포스포디에스테라제를 억제하는 성기능 장애 치료용피라졸로피리미디논 제조용 중간체의 제조 방법
GB9722520D0 (en) 1997-10-24 1997-12-24 Pfizer Ltd Compounds
SK15532000A3 (sk) 1998-04-20 2001-12-03 Pfizer Inc. Pyrazolopyrimidínové inhibítory cgmp pde5 na použitie na liečbu sexuálnych dysfunkcií, spôsob ich prípravy, medziprodukty a farmaceutický prostriedok s ich obsahom
GB9823101D0 (en) 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
GB9823102D0 (en) 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
GB9823103D0 (en) 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
US6225315B1 (en) * 1998-11-30 2001-05-01 Pfizer Inc Method of treating nitrate-induced tolerance
GB9828340D0 (en) * 1998-12-22 1999-02-17 Novartis Ag Organic compounds
NZ517324A (en) 1999-10-11 2003-09-26 Pfizer 5-(2-substituted-5-heterocyclylsulphonylpyrid-3-YL)- dihydropyrazolo[4,3-d]pyrimidin-7-ones as phosphodiesterase inhibitors
TWI265925B (en) 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
EA008596B1 (ru) 2003-04-29 2007-06-29 Пфайзер Инк. 5,7-ДИАМИНОПИРАЗОЛО[4,3-d]ПИРИМИДИНЫ, ПОЛЕЗНЫЕ ПРИ ЛЕЧЕНИИ ГИПЕРТЕНЗИИ
JP2007504243A (ja) * 2003-09-03 2007-03-01 ニューロジェン・コーポレーション ５−アリール−ピラゾロ［４，３−ｄ］ピリミジン類、ピリジン類、ピラジン類及び関連化合物
BR112014013178A2 (pt) 2011-12-09 2017-06-13 Chiesi Farm Spa composto, composição farmacêutica e uso de um composto
BR112014030410A2 (pt) * 2012-06-07 2017-06-27 Hoffmann La Roche inibidores de pirazolopirimidona e pirazolopiridona de tanquirase
US8883857B2 (en) 2012-12-07 2014-11-11 Baylor College Of Medicine Small molecule xanthine oxidase inhibitors and methods of use
KR102590848B1 (ko) 2016-12-28 2023-10-19 다트 뉴로사이언스, 엘엘씨 Pde2 억제제로서 치환된 피라졸로피리미디논 화합물
ES2902365T3 (es) 2017-11-27 2022-03-28 Dart Neuroscience Llc Compuestos de furanopirimidina sustituidos como inhibidores de PDE1
IL316462A (en) 2022-04-22 2024-12-01 Vertex Pharma Heteroaryl compounds for the treatment of pain

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211732A (en) * 1965-10-12 Pyrazolob:x-d]pyrlil/hdines
US3165520A (en) * 1965-01-12 Certificate of correction
CH398626A (de) * 1960-05-11 1966-03-15 Ciba Geigy Verfahren zur Herstellung neuer Pyrazolopyrimidine
GB937722A (en) * 1960-05-11 1963-09-25 Ciba Ltd New pyrazolopyrimidines and process for the preparation thereof
GB1284084A (en) * 1969-04-17 1972-08-02 Delmar Chem PROCESS FOR MAKING 1H-PYRAZOLO[3,4-d]PYRIMIDINES
US3732225A (en) * 1970-07-23 1973-05-08 Squibb & Sons Inc Pyrazolo(3,4-d)pyrimidine derivatives
US4666908A (en) * 1985-04-05 1987-05-19 Warner-Lambert Company 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use
WO1988000192A1 (en) * 1986-06-26 1988-01-14 Warner-Lambert Company 5-SUBSTITUTED PYRAZOLO[4,3-d]PYRIMIDIN-7-ONES
US5075310A (en) * 1988-07-01 1991-12-24 Smith Kline & French Laboratories, Ltd. Pyrimidone derivatives as bronchodilators
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9121028D0 (en) * 1991-10-03 1991-11-13 Pfizer Ltd Therapeutic agents
US5294612A (en) * 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
GB9315017D0 (en) * 1993-07-20 1993-09-01 Glaxo Lab Sa Chemical compounds

Also Published As

Publication number Publication date
EP0813534A1 (en) 1997-12-29
ZA961948B (en) 1996-09-17
WO1996028448A1 (en) 1996-09-19
EP0813534A4 (en) 1998-06-10
PL322452A1 (en) 1998-02-02
HUP9801394A2 (hu) 1998-10-28
AU5093396A (en) 1996-10-02
US5736548A (en) 1998-04-07
JPH11501926A (ja) 1999-02-16
US5958929A (en) 1999-09-28
NO974150D0 (no) 1997-09-09
AU708809B2 (en) 1999-08-12
HUP9801394A3 (en) 2000-07-28
KR19980702892A (ko) 1998-08-05
MX9706878A (es) 1998-06-28
CZ280697A3 (cs) 1998-04-15
CA2211729A1 (en) 1996-09-19
NZ303886A (en) 1998-11-25

Similar Documents

Publication Publication Date Title
NO974150L (no) 6-arylpyrazolo[3,4-d]pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav
ATE182892T1 (de) Mercaptoacetylamide von pyridazo(1,2-a>(1,2>- diazepin -derivaten als eukephalinase und ace- inhibitoren
NO984082D0 (no) Pyrimido£5,4-d|pyrimidiner, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte for fremstilling derav
NO995006L (no) Nye forbindelser
CA2137203A1 (en) Protein kinase c inhibitors
CA2216535A1 (en) Protein kinase c inhibitors
DK0779888T3 (da) Pyrimido[5,4-d]pyrimidiner, lægemidler indeholdende disse forbindelser, anvendelse deraf og fremgangsmåder til fremstilling
DK0708772T3 (da) Imidazo[4,5,-c]pyridin-4-aminer
NO974151D0 (no) 6-substituerte pyrazolo (3,4-d) pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav
CA2263561A1 (en) Thienopyrimidines
NO984081D0 (no) Pyrimido£5,4-d|pyrimidiner, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte for fremtilling derav
TR199800012T1 (xx) Piroloprimidinler ve preparasyon i�in tatbikler.
MY118068A (en) Protein kinase c inhibitor
MD1861F2 (en) Derivatives of the 6-arylpyrido[2,3-d]pyrimidines and naphthyridines, pharmaceutical composition on base thereof, methods of treatment and inhibition of the tyrosine kinaze receptor celle proliferation and migration
TR200000197T2 (tr) Yeni bileşimler
IL118269A0 (en) Tetralin derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
BR9907788A (pt) Agentes antiinflamatórios seletivos paraglicocorticóides
NO993027L (no) Pyrrolo[3,4-D]pyrimidinonderivater og deres anvendelse som legemidler
IE873339L (en) 6-Benzoxazinyl- and¹6-benzothiazinyl-2,3,4,5-tetrahydropyridazin -3-ones.
MY115211A (en) Novel amino acid derivatives, their preparation and use
EP0272914A3 (en) 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones
FR2713234B1 (fr) Nouveaux dérivés de la triphénodioxazine, leur préparation et leur utilisation comme pigments.
NZ324118A (en) Furan-and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of the replication of hiv-1 and hiv-1 mutants
PT935598E (pt) Derivados de 3-oxo-pirido (1,2-a)benzimidazole-4-carboxamida alquilo substituidos contendo 5 heteroatomos uteis no tratamento de disturbios do sistema nervoso central
GEP20084346B (en) Protein kinase c inhibitors