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NO962812L - Fremgangsmåte for behandling av neurogen inflammasjon - Google Patents

Fremgangsmåte for behandling av neurogen inflammasjon

Info

Publication number
NO962812L
NO962812L NO962812A NO962812A NO962812L NO 962812 L NO962812 L NO 962812L NO 962812 A NO962812 A NO 962812A NO 962812 A NO962812 A NO 962812A NO 962812 L NO962812 L NO 962812L
Authority
NO
Norway
Prior art keywords
neurogenic inflammation
procedure
treatment
alkoxy
cgb
Prior art date
Application number
NO962812A
Other languages
English (en)
Other versions
NO962812D0 (no
Inventor
Knud Erik Andersen
Uffe Bang Olsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO962812D0 publication Critical patent/NO962812D0/no
Publication of NO962812L publication Critical patent/NO962812L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Fremgangsmåte for behandling av neurogen inflammasjon hos et individ som trenger det, omfattende admini- strering av en effektiv mengde av en forbindelse med formel (I) \ .(CHjJnCGB. (D hvor R1 og R2 uavhengig av hverandre er hydrogen, halogen, trifluormetyl, Ct_6- alkyl eller C^-alkoksy; Y er >N-CH2-, >CH-CH2- eller >C=CH- når s er O, l eller 2, eller Y er >CH-CH=N- eller >C=N- når s er O, hvor bare det under- strekede atom deltar i ringsystemet; X er -O-; Z er -O-, -S-, -CH2-, -CH2- CH2-, -CH=CH-CH2-, -CH2-CH=CH-, -CH2CH2- CH2-, -CH=CH- eller -O-CH2-; R4 og R5 er hver hydrogen eller kan, når m er 2, til sammen være en binding; R6 er OH eller C^-alkoksy; p er O eller 1; qer O eller 1; ser O, l eller 2; rer 2, 3 eller 4; mer l eller 2; ner l når m er l, eller n er O når m er 2; eller et farmasøytisk akseptabelt salt derav, til individet.
NO962812A 1994-01-04 1996-07-03 Fremgangsmåte for behandling av neurogen inflammasjon NO962812L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK2094 1994-01-04
PCT/DK1995/000003 WO1995018615A1 (en) 1994-01-04 1995-01-03 A method of treating neurogenic inflammation

Publications (2)

Publication Number Publication Date
NO962812D0 NO962812D0 (no) 1996-07-03
NO962812L true NO962812L (no) 1996-09-04

Family

ID=8088844

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962812A NO962812L (no) 1994-01-04 1996-07-03 Fremgangsmåte for behandling av neurogen inflammasjon

Country Status (13)

Country Link
EP (1) EP0735872A1 (no)
JP (1) JPH09507849A (no)
CN (1) CN1142183A (no)
AU (1) AU1311195A (no)
BR (1) BR9506453A (no)
CA (1) CA2180239A1 (no)
CZ (1) CZ198396A3 (no)
FI (1) FI962750A7 (no)
HU (1) HUT76281A (no)
IL (1) IL112223A0 (no)
NO (1) NO962812L (no)
WO (1) WO1995018615A1 (no)
ZA (1) ZA9530B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022342A1 (en) * 1995-12-15 1997-06-26 Novo Nordisk A/S Novel method
US7417040B2 (en) 2004-03-01 2008-08-26 Bristol-Myers Squibb Company Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965639A (en) * 1960-12-20 New basically substituted azepine
FI864246A7 (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
DK93791D0 (da) * 1991-05-17 1991-05-17 Novo Nordisk As Nye heterocykliske carboxylsyrer

Also Published As

Publication number Publication date
CN1142183A (zh) 1997-02-05
JPH09507849A (ja) 1997-08-12
CZ198396A3 (en) 1997-01-15
BR9506453A (pt) 1997-09-02
EP0735872A1 (en) 1996-10-09
HU9601826D0 (en) 1996-09-30
FI962750L (fi) 1996-09-04
CA2180239A1 (en) 1995-07-13
FI962750A0 (fi) 1996-07-04
ZA9530B (en) 1996-07-04
NO962812D0 (no) 1996-07-03
AU1311195A (en) 1995-08-01
FI962750A7 (fi) 1996-09-04
HUT76281A (en) 1997-07-28
IL112223A0 (en) 1995-03-30
WO1995018615A1 (en) 1995-07-13

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