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NO965301L - 2,4,6-trijod-5-substituerte-amino-isoftalatestere nyttige som röntgenkontrastmidler for medisinsk diagnostisk billeddannelse - Google Patents

2,4,6-trijod-5-substituerte-amino-isoftalatestere nyttige som röntgenkontrastmidler for medisinsk diagnostisk billeddannelse

Info

Publication number
NO965301L
NO965301L NO965301A NO965301A NO965301L NO 965301 L NO965301 L NO 965301L NO 965301 A NO965301 A NO 965301A NO 965301 A NO965301 A NO 965301A NO 965301 L NO965301 L NO 965301L
Authority
NO
Norway
Prior art keywords
contrast agents
medical diagnostic
triiod
amino
substituted
Prior art date
Application number
NO965301A
Other languages
English (en)
Other versions
NO965301D0 (no
Inventor
Edward R Bacon
Sol J Daum
Kimberly G Estep
Original Assignee
Nanosystems Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosystems Llc filed Critical Nanosystems Llc
Publication of NO965301L publication Critical patent/NO965301L/no
Publication of NO965301D0 publication Critical patent/NO965301D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser med struktur (I) hvor Q er (II); er et tall fra 0 til 20; Rer H, alkyl, fluoralkyl, cykloalkyl, aryl, aralkyl, alkoksyalkyl eller acetamid-alkyl;2,3,og Rer uavhengig H, alkyl, fluoralkyl, halogen, hydroksy, acylamino, acetamido-alkyl, cyano, sulfonyl, karboksamido eller sulfonamido; Rer alkyl, cykloalkyl, aryl eller aralkyl; og Rer H eller -C00Rer nyttige som kontrastmidler i medisinske diagnostiske røntgenbilleddannende sammensetninger og fremgangsmåter.
NO965301A 1994-06-24 1996-12-11 2,4,6-trijod-5-substituerte-amino-isoftalatestere nyttige som röntgenkontrastmidler for medisinsk diagnostisk billeddannelse NO965301D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26559094A 1994-06-24 1994-06-24
PCT/US1995/007400 WO1996000210A1 (en) 1994-06-24 1995-06-09 2,4,6-triiodo-5-substituted-amino-isophthalate esters useful as x-ray contrast agents for medical diagnostic imaging

Publications (2)

Publication Number Publication Date
NO965301L true NO965301L (no) 1996-12-11
NO965301D0 NO965301D0 (no) 1996-12-11

Family

ID=23011079

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965301A NO965301D0 (no) 1994-06-24 1996-12-11 2,4,6-trijod-5-substituerte-amino-isoftalatestere nyttige som röntgenkontrastmidler for medisinsk diagnostisk billeddannelse

Country Status (9)

Country Link
US (1) US5670136A (no)
EP (1) EP0766663A1 (no)
JP (1) JPH10502083A (no)
AU (1) AU2823795A (no)
CA (1) CA2191983A1 (no)
FI (1) FI965094L (no)
IL (1) IL114305A0 (no)
NO (1) NO965301D0 (no)
WO (1) WO1996000210A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
US6375986B1 (en) 2000-09-21 2002-04-23 Elan Pharma International Ltd. Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
US6969529B2 (en) 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6270806B1 (en) 1999-03-03 2001-08-07 Elan Pharma International Limited Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions
US6797820B2 (en) * 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
US7998507B2 (en) * 2000-09-21 2011-08-16 Elan Pharma International Ltd. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors
US7198795B2 (en) 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
US20030152519A1 (en) * 2001-11-07 2003-08-14 Reinhard Koenig Methods for vascular imaging using nanoparticulate contrast agents
WO2003082213A2 (en) * 2002-03-28 2003-10-09 Imcor Pharmaceutical Company Compositions and methods for delivering pharmaceutically active agents using nanoparticulates
FR3062850B1 (fr) 2017-02-10 2020-01-31 Guerbet Procede de preparation monotope de composes organo-iodes
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2820814A (en) * 1955-03-21 1958-01-21 Schering Corp Polyiodinated 5-aminoisophthalic acids, salts, and esters
NL239757A (no) * 1958-06-03
US3144479A (en) * 1958-08-07 1964-08-11 Chemie Linz Ag New iodine-containing benzoic acid esters
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters
US5344638A (en) * 1993-03-11 1994-09-06 Sterling Winthrop Inc. Compositions of iodobenzoic acid derivatives for visualization of the gastrointestinal tract
US5264610A (en) * 1993-03-29 1993-11-23 Sterling Winthrop Inc. Iodinated aromatic propanedioates

Also Published As

Publication number Publication date
CA2191983A1 (en) 1996-01-04
IL114305A0 (en) 1995-10-31
WO1996000210A1 (en) 1996-01-04
FI965094A7 (fi) 1996-12-18
EP0766663A1 (en) 1997-04-09
JPH10502083A (ja) 1998-02-24
US5670136A (en) 1997-09-23
FI965094A0 (fi) 1996-12-18
FI965094L (fi) 1996-12-18
NO965301D0 (no) 1996-12-11
AU2823795A (en) 1996-01-19

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