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NO964871L - Nye agonistforbindelser - Google Patents

Nye agonistforbindelser

Info

Publication number
NO964871L
NO964871L NO964871A NO964871A NO964871L NO 964871 L NO964871 L NO 964871L NO 964871 A NO964871 A NO 964871A NO 964871 A NO964871 A NO 964871A NO 964871 L NO964871 L NO 964871L
Authority
NO
Norway
Prior art keywords
agonist compounds
new agonist
new
compounds
therapy
Prior art date
Application number
NO964871A
Other languages
English (en)
Norwegian (no)
Other versions
NO964871D0 (no
Inventor
Helmut Schmidhammer
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO964871D0 publication Critical patent/NO964871D0/no
Publication of NO964871L publication Critical patent/NO964871L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO964871A 1994-05-18 1996-11-15 Nye agonistforbindelser NO964871L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401727A SE9401727D0 (sv) 1994-05-18 1994-05-18 New compounds I
PCT/SE1995/000504 WO1995031464A1 (en) 1994-05-18 1995-05-09 New agonist compounds

Publications (2)

Publication Number Publication Date
NO964871D0 NO964871D0 (no) 1996-11-15
NO964871L true NO964871L (no) 1996-11-15

Family

ID=20394058

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964871A NO964871L (no) 1994-05-18 1996-11-15 Nye agonistforbindelser

Country Status (18)

Country Link
US (1) US5886001A (is)
EP (1) EP0759923A1 (is)
JP (1) JPH10500132A (is)
CN (1) CN1152314A (is)
AU (1) AU690281B2 (is)
BR (1) BR9507656A (is)
CA (1) CA2189139A1 (is)
FI (1) FI964576A0 (is)
HU (1) HU9603171D0 (is)
IL (1) IL113627A0 (is)
IS (1) IS4381A (is)
NO (1) NO964871L (is)
NZ (1) NZ287177A (is)
PL (1) PL317250A1 (is)
SE (1) SE9401727D0 (is)
SK (1) SK139696A3 (is)
WO (1) WO1995031464A1 (is)
ZA (1) ZA953699B (is)

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US5849731A (en) * 1995-09-26 1998-12-15 Toray Industries, Inc. Indole derivatives and medical application thereof
ES2217533T3 (es) * 1997-01-16 2004-11-01 Toray Industries, Inc. Derivados de indolomorfinano y medicamentos/preventivos para transtornos cerebrales.
GB9717629D0 (en) * 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents
US6500824B1 (en) * 1998-08-06 2002-12-31 Regents Of The University Of Minnesota Kappa (OP2) opioid receptor antagonists
US7232829B2 (en) 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
WO2002080919A1 (en) * 2001-04-06 2002-10-17 Regents Of The University Of Minnesota Therapeutic compounds and methods
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung
KR101255074B1 (ko) 2003-10-01 2013-04-16 아돌로 코포레이션 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
JP2010503669A (ja) 2006-09-12 2010-02-04 アドラー コーポレーション 認知機能の強化のためのｎ含有スピロ化合物の使用
US9321116B2 (en) * 2009-03-05 2016-04-26 United Technologies Corporation Cold metal transfer gas metal arc welding apparatus and method of operation
EP2340832A1 (en) 2009-12-23 2011-07-06 Universität Innsbruck Morphinan-6-one compounds for the treatment or prevention of neurodegenerative diseases
JP6091426B2 (ja) * 2010-12-23 2017-03-08 フェニックス ファーマラブス インク 鎮痛剤として有用な新規モルフィナン類
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
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CN104603097A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗多发性硬化症的组合物和方法
EP2852570B1 (en) 2012-05-23 2020-04-22 Cellixbio Private Limited Composition for the treatment of inflammatory bowel disease
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
US9187427B2 (en) 2012-08-03 2015-11-17 Cellix Bio Private Limited N-substituted nicotinamide compounds and compositions for the treatment migraine and neurologic diseases
US9624168B2 (en) 2012-09-06 2017-04-18 Cellix Bio Private Limited Compositions and methods for the treatment inflammation and lipid disorders
CN104364231A (zh) 2012-09-08 2015-02-18 塞利克斯比奥私人有限公司 用于治疗炎症和脂质异常的组合物和方法
HU231191B1 (hu) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Izotóp tartalmú morfin molekulák
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
EP3004049B1 (en) 2013-06-04 2018-09-05 Cellixbio Private Limited Compositions and methods for the treatment of diabetes and pre-diabetes
EP3077398B1 (en) 2013-12-05 2020-03-11 The University of Bath Novel opioid compounds and their uses
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
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ES2787223T3 (es) 2014-11-07 2020-10-15 Univ Minnesota Sales y composiciones útiles para tratar enfermedades
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
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Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics
DK0577847T3 (da) * 1992-01-23 1999-06-23 Toray Industries Morphinanderivat og medicinsk anvendelse deraf
ATE239732T1 (de) * 1992-09-29 2003-05-15 Toray Industries Indol-derivat, verfahren zu dessen herstellung und dessen medizinische anwendung
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5780479A (en) * 1997-04-04 1998-07-14 Regents Of The University Of Minnesota Use of opioid antagonists to treat impulse-control disorders

Also Published As

Publication number Publication date
IL113627A0 (en) 1995-08-31
ZA953699B (en) 1995-11-20
EP0759923A1 (en) 1997-03-05
NO964871D0 (no) 1996-11-15
NZ287177A (en) 1997-11-24
US5886001A (en) 1999-03-23
AU2581895A (en) 1995-12-05
CA2189139A1 (en) 1995-11-23
SK139696A3 (en) 1997-05-07
FI964576A7 (fi) 1996-11-15
FI964576L (fi) 1996-11-15
CN1152314A (zh) 1997-06-18
AU690281B2 (en) 1998-04-23
FI964576A0 (fi) 1996-11-15
HU9603171D0 (en) 1997-01-28
WO1995031464A1 (en) 1995-11-23
SE9401727D0 (sv) 1994-05-18
BR9507656A (pt) 1997-09-23
IS4381A (is) 1996-11-08
PL317250A1 (en) 1997-04-01
JPH10500132A (ja) 1998-01-06

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