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NO953280D0 - Pyrrolidenmetylderivater og fremgangsmåte for deres fremstilling - Google Patents

Pyrrolidenmetylderivater og fremgangsmåte for deres fremstilling

Info

Publication number
NO953280D0
NO953280D0 NO953280A NO953280A NO953280D0 NO 953280 D0 NO953280 D0 NO 953280D0 NO 953280 A NO953280 A NO 953280A NO 953280 A NO953280 A NO 953280A NO 953280 D0 NO953280 D0 NO 953280D0
Authority
NO
Norway
Prior art keywords
alkyl
alkoxy
alkenyl
substituted
unsubstituted
Prior art date
Application number
NO953280A
Other languages
English (en)
Other versions
NO305796B1 (no
NO953280L (no
Inventor
Gianfederico Doria
Anna Maria Isetta
Marcellino Tibolla
Maria Chiara Fornasiero
Mario Ferrari
Domenico Trizio
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of NO953280D0 publication Critical patent/NO953280D0/no
Publication of NO953280L publication Critical patent/NO953280L/no
Publication of NO305796B1 publication Critical patent/NO305796B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
NO953280A 1993-12-23 1995-08-21 Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomprodukt NO305796B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939326284A GB9326284D0 (en) 1993-12-23 1993-12-23 Pyrrolydenemethyl-derivatives and process for their preparation
PCT/EP1994/004006 WO1995017381A1 (en) 1993-12-23 1994-12-02 Novel 2,2'-bi-1h-pyrrole derivatives with immunosuppressant activity

Publications (3)

Publication Number Publication Date
NO953280D0 true NO953280D0 (no) 1995-08-21
NO953280L NO953280L (no) 1995-08-21
NO305796B1 NO305796B1 (no) 1999-07-26

Family

ID=10747089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953280A NO305796B1 (no) 1993-12-23 1995-08-21 Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomprodukt

Country Status (25)

Country Link
US (1) US5691334A (no)
EP (2) EP1241162A1 (no)
JP (1) JP3594311B2 (no)
KR (1) KR100365057B1 (no)
CN (1) CN1120153C (no)
AT (1) ATE224874T1 (no)
AU (1) AU689169B2 (no)
CA (1) CA2155096A1 (no)
DE (1) DE69431429T2 (no)
DK (1) DK0686147T3 (no)
ES (1) ES2184786T3 (no)
FI (1) FI109688B (no)
GB (1) GB9326284D0 (no)
HU (1) HUT73663A (no)
IL (1) IL112022A (no)
MY (1) MY113304A (no)
NO (1) NO305796B1 (no)
NZ (1) NZ276716A (no)
PL (1) PL183112B1 (no)
PT (1) PT686147E (no)
RU (1) RU2145957C1 (no)
TW (1) TW285670B (no)
UA (1) UA57697C2 (no)
WO (1) WO1995017381A1 (no)
ZA (1) ZA9410203B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1009856A5 (fr) * 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
GB9603212D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives
GB9619706D0 (en) * 1996-09-20 1996-11-06 Pharmacia Spa Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und
GB9705035D0 (en) * 1997-03-11 1997-04-30 Pharmacia & Upjohn Spa Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation
US5989591A (en) * 1997-03-14 1999-11-23 American Home Products Corporation Rapamycin formulations for oral administration
KR100252197B1 (ko) * 1997-09-20 2000-04-15 박호군 세라시아 마르세센스 균주의 배양액으로 부터 분리한 면역억제제용 프로디지오신
GB9802745D0 (en) 1998-02-09 1998-04-08 Pharmacia & Upjohn Spa Benzyloxy prodigiosine compounds
US20040014987A1 (en) * 2000-01-26 2004-01-22 Gemin X Biotechnologies Inc. Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
US6407244B1 (en) 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
KR20010081515A (ko) * 2000-02-15 2001-08-29 복성해 프로디지오신의 당뇨병 예방 및 치료용 조성물
KR100392225B1 (ko) * 2001-04-19 2003-07-22 한국생명공학연구원 류머티스 관절염 치료용 프로디지오신 조성물
US7144912B2 (en) 2001-07-18 2006-12-05 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression
PL1644363T3 (pl) * 2003-05-30 2012-07-31 Gemin X Pharmaceuticals Canada Inc Związki triheterocykliczne, kompozycje i metody leczenia raka
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
WO2006089397A1 (en) * 2005-02-22 2006-08-31 Gemin X Biotechnologies Inc. Methods for treating arthritis using triheterocyclic compounds
KR100674222B1 (ko) * 2005-07-11 2007-01-24 한국생명공학연구원 세라시아 마르세센스 ｂ-1231 ｋｃｔｃ 0386ｂｐ로부터분리한 프로디지오신을 유효성분으로 포함한 급성이식편대숙주병의 예방 및 치료용 조성물
CA2636275C (en) 2006-01-06 2013-02-12 Sepracor Inc. Tetralone-based monoamine reuptake inhibitors
AU2007205114B2 (en) 2006-01-06 2012-11-08 Sunovion Pharmaceuticals Inc. Cycloalkylamines as monoamine reuptake inhibitors
AU2007233041B2 (en) 2006-03-31 2013-05-02 Sepracor Inc. Preparation of chiral amides and amines
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US20080051400A1 (en) * 2006-07-06 2008-02-28 Gemin X Biotechnologies Inc. Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
AU2008259841B2 (en) 2007-05-31 2015-02-05 Sunovion Pharmaceuticals Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
CN103387529B (zh) * 2013-07-30 2016-03-30 中国农业科学院烟草研究所 抗tmv的三吡咯环类化合物及其制备方法和用途
ES2615077B1 (es) * 2015-12-02 2018-03-14 Universidad De Burgos Una nueva familia de compuestos, procedimiento de obtención de los mismos y sus usos en el tratamiento y/o profilaxis de enfermedades

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280429A (ja) * 1985-06-06 1986-12-11 Chugai Pharmaceut Co Ltd 免疫抑制剤
SU1409276A1 (ru) * 1985-11-10 1988-07-15 Донецкий медицинский институт им.М.Горького Способ лечени острых кишечных инфекций
JPH02250828A (ja) * 1989-03-23 1990-10-08 Nippon Kayaku Co Ltd 新規免疫抑制剤

Also Published As

Publication number Publication date
HUT73663A (en) 1996-09-30
JPH08507090A (ja) 1996-07-30
CA2155096A1 (en) 1995-06-29
NO305796B1 (no) 1999-07-26
US5691334A (en) 1997-11-25
WO1995017381A1 (en) 1995-06-29
IL112022A0 (en) 1995-03-15
AU1109095A (en) 1995-07-10
PL310387A1 (en) 1995-12-11
IL112022A (en) 1998-12-27
HU9502782D0 (en) 1995-11-28
GB9326284D0 (en) 1994-02-23
KR960701009A (ko) 1996-02-24
TW285670B (no) 1996-09-11
ES2184786T3 (es) 2003-04-16
CN1120153C (zh) 2003-09-03
PT686147E (pt) 2003-02-28
JP3594311B2 (ja) 2004-11-24
FI953919A0 (fi) 1995-08-21
DK0686147T3 (da) 2003-02-03
AU689169B2 (en) 1998-03-26
FI109688B (fi) 2002-09-30
EP0686147A1 (en) 1995-12-13
UA57697C2 (uk) 2003-07-15
CN1118164A (zh) 1996-03-06
MY113304A (en) 2002-01-31
FI953919A7 (fi) 1995-08-21
ZA9410203B (en) 1995-10-20
DE69431429T2 (de) 2003-05-15
ATE224874T1 (de) 2002-10-15
EP1241162A1 (en) 2002-09-18
DE69431429D1 (de) 2002-10-31
PL183112B1 (pl) 2002-05-31
EP0686147B1 (en) 2002-09-25
NO953280L (no) 1995-08-21
KR100365057B1 (ko) 2003-06-09
NZ276716A (en) 1996-12-20
RU2145957C1 (ru) 2000-02-27

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