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NO952559L - N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler - Google Patents

N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler

Info

Publication number
NO952559L
NO952559L NO952559A NO952559A NO952559L NO 952559 L NO952559 L NO 952559L NO 952559 A NO952559 A NO 952559A NO 952559 A NO952559 A NO 952559A NO 952559 L NO952559 L NO 952559L
Authority
NO
Norway
Prior art keywords
gastrin
pyrrolidines
cholecystokinin
acyl
drugs
Prior art date
Application number
NO952559A
Other languages
English (en)
Other versions
NO952559D0 (no
Inventor
Marc Capet
Marie-Christine Dubroeucq
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO952559L publication Critical patent/NO952559L/no
Publication of NO952559D0 publication Critical patent/NO952559D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Forbindelser med formelen: N l J CO-CH-NH-CO-R5 (II der substituentene har diverse betydninger. Forbindelsene rapporteres å ha Interessante farmakologiske egenskaper, særlig en sterk affinitet for reseptorer for cholecystoklnln (CCK) og gastrln. Forblndelsenes fremstilling beskrives. Videre beskrives medikamenter Inneholdende . forbindelsene samt deres fremstilling.
NO952559A 1993-01-07 1995-06-26 N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler NO952559D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9300077A FR2700165B1 (fr) 1993-01-07 1993-01-07 Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
PCT/FR1994/000008 WO1994015914A1 (fr) 1993-01-07 1994-01-03 N-acyl pyrrolidines et des medicaments pour le traitement ou la prevention des desordres lies a la ckk et la gastrine

Publications (2)

Publication Number Publication Date
NO952559L true NO952559L (no) 1995-06-26
NO952559D0 NO952559D0 (no) 1995-06-26

Family

ID=9442866

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952559A NO952559D0 (no) 1993-01-07 1995-06-26 N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler

Country Status (19)

Country Link
US (1) US5624939A (no)
EP (1) EP0678088B1 (no)
JP (1) JPH08505614A (no)
KR (1) KR960700228A (no)
AT (1) ATE143946T1 (no)
AU (1) AU5819294A (no)
CA (1) CA2152281A1 (no)
DE (1) DE69400702T2 (no)
DK (1) DK0678088T3 (no)
ES (1) ES2094048T3 (no)
FR (1) FR2700165B1 (no)
GR (1) GR3021313T3 (no)
HU (1) HUT74095A (no)
IL (1) IL108290A0 (no)
NO (1) NO952559D0 (no)
NZ (1) NZ259398A (no)
RU (1) RU95116448A (no)
WO (1) WO1994015914A1 (no)
ZA (1) ZA9480B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2721608B1 (fr) * 1994-06-22 1996-07-19 Rhone Poulenc Rorer Sa Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2744361B1 (fr) * 1996-02-07 1998-02-27 Rhone Poulenc Rorer Sa Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
FR2744362B1 (fr) * 1996-02-07 1998-02-27 Rhone Poulenc Rorer Sa Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
TW442449B (en) 1996-07-04 2001-06-23 Hoechst Ag Process for preparing 1,2-dichloroethane by direct chlorination
US6737409B2 (en) * 2001-07-19 2004-05-18 Hoffmann-La Roche Inc. Dolastatin 10 derivatives
DE10218377B4 (de) * 2002-04-25 2004-03-11 Rea Gesellschaft Für Recycling Von Energie Und Abfall Mbh Verfahren und Vorrichtung zur Schwerstoffabtrennung aus Aufschlämmungen
US8247438B2 (en) 2008-02-27 2012-08-21 Neuropill, Inc. Methods for treating schizophrenia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
FR2667864B2 (fr) * 1990-03-07 1994-08-05 Rhone Poulenc Sante Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
FR2678938B1 (fr) * 1991-07-10 1993-10-08 Rhone Poulenc Rorer Sa Derives de pyrrolidine, leur preparation et les medicaments les contenant.

Also Published As

Publication number Publication date
EP0678088B1 (fr) 1996-10-09
JPH08505614A (ja) 1996-06-18
US5624939A (en) 1997-04-29
AU5819294A (en) 1994-08-15
ZA9480B (en) 1994-08-11
IL108290A0 (en) 1994-04-12
DK0678088T3 (da) 1996-11-18
HUT74095A (en) 1996-11-28
HU9502067D0 (en) 1995-09-28
DE69400702T2 (de) 1997-03-06
ES2094048T3 (es) 1997-01-01
DE69400702D1 (de) 1996-11-14
RU95116448A (ru) 1997-06-10
FR2700165B1 (fr) 1995-02-17
EP0678088A1 (fr) 1995-10-25
NO952559D0 (no) 1995-06-26
ATE143946T1 (de) 1996-10-15
WO1994015914A1 (fr) 1994-07-21
CA2152281A1 (fr) 1994-07-21
GR3021313T3 (en) 1997-01-31
NZ259398A (en) 1996-02-27
KR960700228A (ko) 1996-01-19
FR2700165A1 (fr) 1994-07-08

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