NO943909D0 - Laktam-dipeptider som har HLE-inhiberende aktivitet - Google Patents

Laktam-dipeptider som har HLE-inhiberende aktivitet

Info

Publication number: NO943909D0
Authority: NO; Norway
Prior art keywords: heterocyclic compounds; hle; dipeptides; lactam; inhibitory activity
Prior art date: 1992-04-16

Application number

NO943909A

Other languages

English (en)

Other versions

NO943909L (no

Inventor

Peter Robert Bernstein

Royston Martin Thomas

Peter Warner

Donald John Wolanin

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-16

Filing date

1994-10-14

Publication date

1994-10-14

1992-04-16 Priority claimed from GB929208380A external-priority patent/GB9208380D0/en

1992-04-16 Priority claimed from GB929208379A external-priority patent/GB9208379D0/en

1992-07-08 Priority claimed from GB929214448A external-priority patent/GB9214448D0/en

1992-08-14 Priority claimed from GB929217363A external-priority patent/GB9217363D0/en

1992-08-14 Priority claimed from GB929217364A external-priority patent/GB9217364D0/en

1992-08-14 Priority claimed from GB929217362A external-priority patent/GB9217362D0/en

1994-10-14 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1994-10-14 Publication of NO943909L publication Critical patent/NO943909L/no

1994-10-14 Publication of NO943909D0 publication Critical patent/NO943909D0/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO943909A 1992-04-16 1994-10-14 Laktam-dipeptider som har HLE-inhiberende aktivitet NO943909D0 (no)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
GB929208380A GB9208380D0 (en)	1992-04-16	1992-04-16	Heterocyclic compounds
GB929208379A GB9208379D0 (en)	1992-04-16	1992-04-16	Heterocyclic amines
GB929214448A GB9214448D0 (en)	1992-07-08	1992-07-08	Heterocyclic agents
GB929217363A GB9217363D0 (en)	1992-08-14	1992-08-14	Heterocyclic amines
GB929217364A GB9217364D0 (en)	1992-08-14	1992-08-14	Heterocyclic agents
GB929217362A GB9217362D0 (en)	1992-08-14	1992-08-14	Heterocyclic compounds
PCT/GB1993/000794 WO1993021212A1 (en)	1992-04-16	1993-04-15	Lactam dipeptides having hle inhibiting activity

Publications (2)

Publication Number	Publication Date
NO943909L NO943909L (no)	1994-10-14
NO943909D0 true NO943909D0 (no)	1994-10-14

Family

ID=27547161

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO943909A NO943909D0 (no)	1992-04-16	1994-10-14	Laktam-dipeptider som har HLE-inhiberende aktivitet

Country Status (13)

Country	Link
EP (1)	EP0630382B1 (no)
JP (1)	JPH07505873A (no)
AT (1)	ATE149175T1 (no)
AU (1)	AU4076993A (no)
CA (1)	CA2132543A1 (no)
DE (1)	DE69308291T2 (no)
FI (1)	FI944802L (no)
GB (1)	GB9307555D0 (no)
HU (1)	HUT70430A (no)
IL (1)	IL105424A0 (no)
MX (1)	MX9302215A (no)
NO (1)	NO943909D0 (no)
WO (1)	WO1993021212A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6159938A (en) *	1994-11-21	2000-12-12	Cortech, Inc.	Serine protease inhibitors comprising α-keto heterocycles
US6150334A (en) *	1994-11-21	2000-11-21	Cortech, Inc.	Serine protease inhibitors-tripeptoid analogs
US5998379A (en) *	1994-11-21	1999-12-07	Cortech Inc.	Serine protease inhibitors-proline analogs
US6100238A (en) *	1994-11-21	2000-08-08	Cortech Inc.	Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors
US5618792A (en) *	1994-11-21	1997-04-08	Cortech, Inc.	Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
US6001813A (en) *	1994-11-21	1999-12-14	Cortech Inc.	Val-pro containing α-keto oxadiazoles as serine protease inhibitors
US6001811A (en) *	1994-11-21	1999-12-14	Cortech Inc.	Serine protease inhibitors--N-substituted derivatives
US6001814A (en) *	1994-11-21	1999-12-14	Cortech Inc.	Serine protease inhibitors
US20020119985A1 (en)	1994-11-21	2002-08-29	Albert Gyorkos	Serine protease inhibitors
US6015791A (en) *	1994-11-21	2000-01-18	Cortech Inc.	Serine protease inhibitors-cycloheptane derivatives
EP0826671B1 (en) *	1995-04-27	2004-12-29	Mitsubishi Pharma Corporation	Heterocyclic amide compounds and medicinal use of the same
HUP0100669A3 (en) *	1996-12-06	2001-12-28	Cortech Inc Denver	Peptide derivatives as serine protease inhibitors, their use and pharmaceutical compositions comprising thereof
US6656910B2 (en)	1997-12-04	2003-12-02	Cortech, Inc.	Serine protease inhibitors
EP1089752A4 (en)	1998-06-03	2002-01-02	Cortech Inc	ALPHA-KETO OXADIAZOLE AS A SERINE PROTEASE INHIBITOR
EP1842884A3 (en)	2001-07-30	2010-11-24	Sanko Chemical Industry Co., Ltd.	Antistatic composition and method for production
IL163453A0 (en)	2004-08-10	2009-02-11	Yeda Res & Dev	Enzyme inhibitor in leukemia
EP2424841A1 (en) *	2009-04-27	2012-03-07	Elan Pharmaceuticals Inc.	Pyridinone antagonists of alpha-4 integrins
JP7672641B2 (ja)	2019-09-17	2025-05-08	メレオバイオファーマ４リミテッド	移植片拒絶反応、閉塞性細気管支炎症候群、及び移植片対宿主病の治療に使用するためのアルベレスタット
MX2022012942A (es)	2020-04-16	2023-01-11	Mereo Biopharma 4 Ltd	Metodos que involucran el inhibidor de la elastasa de neutrofilo alvelestat para el tratamiento de enfermedades respiratorias mediadas por deficiencia de alfa-1 antitripsina.
IL312002A (en)	2021-10-20	2024-06-01	Mereo Biopharma 4 Ltd	Neutrophil elastase inhibitors for use in the treatment of fibrosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0369391A3 (en) *	1988-11-15	1991-09-25	Boehringer Ingelheim Pharmaceuticals Inc.	N-substituted amides
GB9207145D0 (en) *	1991-04-18	1992-05-13	Ici Plc	Heterocyclic amides

1993
- 1993-04-13 GB GB939307555A patent/GB9307555D0/en active Pending
- 1993-04-15 JP JP5518137A patent/JPH07505873A/ja active Pending
- 1993-04-15 EP EP93910157A patent/EP0630382B1/en not_active Expired - Lifetime
- 1993-04-15 AU AU40769/93A patent/AU4076993A/en not_active Abandoned
- 1993-04-15 HU HU9402968A patent/HUT70430A/hu unknown
- 1993-04-15 CA CA002132543A patent/CA2132543A1/en not_active Abandoned
- 1993-04-15 FI FI944802A patent/FI944802L/fi not_active Application Discontinuation
- 1993-04-15 AT AT93910157T patent/ATE149175T1/de active
- 1993-04-15 DE DE69308291T patent/DE69308291T2/de not_active Expired - Fee Related
- 1993-04-15 WO PCT/GB1993/000794 patent/WO1993021212A1/en not_active Ceased
- 1993-04-16 IL IL105424A patent/IL105424A0/xx unknown
- 1993-04-16 MX MX9302215A patent/MX9302215A/es unknown
1994
- 1994-10-14 NO NO943909A patent/NO943909D0/no unknown

Also Published As

Publication number	Publication date
FI944802A7 (fi)	1994-10-12
AU4076993A (en)	1993-11-18
EP0630382B1 (en)	1997-02-26
FI944802A0 (fi)	1994-10-12
MX9302215A (es)	1993-10-01
DE69308291D1 (de)	1997-04-03
GB9307555D0 (en)	1993-06-02
NO943909L (no)	1994-10-14
FI944802L (fi)	1994-10-12
CA2132543A1 (en)	1993-10-28
IL105424A0 (en)	1993-08-18
WO1993021212A1 (en)	1993-10-28
ATE149175T1 (de)	1997-03-15
EP0630382A1 (en)	1994-12-28
HU9402968D0 (en)	1995-02-28
HUT70430A (en)	1995-10-30
JPH07505873A (ja)	1995-06-29
DE69308291T2 (de)	1997-06-26

Publication	Publication Date	Title
FI944803A0 (fi)	1994-10-12	HLE-estävää aktiivisuutta omaavia laktaamipeptidejä
NO923197D0 (no)	1992-08-14	Substituerte heterocykliske forbindelser
TW262475B (en)	1995-11-11	Heterocyclic amides, intermediates and process for their preparation and pharmaceutical compositions containing them
NO943909D0 (no)	1994-10-14	Laktam-dipeptider som har HLE-inhiberende aktivitet
AU3959693A (en)	1993-11-18	Alpha-aminoboronic acid peptides and their use as elastase inhibitors
NO943911L (no)	1994-10-14	Pyrimidinyl-acetamider som elastaseinhibitorer
FI946202A0 (fi)	1994-12-30	Fluoria sisältäviä dipeptidejä inhibiittoreina ihmisen lenkosyyttielastaasi-inhibiittoreita vastaan
ATE157099T1 (de)	1997-09-15	Laktam-dipeptide mit inhibierender wirkung auf die menschliche leukozytenelastase
DK0397427T3 (da)	1994-06-06	Fluoramidderivater med human leukocytelastase-inhiberende aktivitet
DK0399688T3 (da)	1994-08-29	Trifluorketopeptidderivater, som er nyttige som human leukocyt-elastaseinhibitorer
NO944659L (no)	1995-01-24	Laktam-dipeptider med HLE-inhiberende aktivitet