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NO942230L - Substituted benzimidazoles, processes for their preparation and their use - Google Patents

Substituted benzimidazoles, processes for their preparation and their use

Info

Publication number
NO942230L
NO942230L NO942230A NO942230A NO942230L NO 942230 L NO942230 L NO 942230L NO 942230 A NO942230 A NO 942230A NO 942230 A NO942230 A NO 942230A NO 942230 L NO942230 L NO 942230L
Authority
NO
Norway
Prior art keywords
compounds
processes
preparation
substituted benzimidazoles
och
Prior art date
Application number
NO942230A
Other languages
Norwegian (no)
Other versions
NO942230D0 (en
Inventor
Karl Bjorn Christer Holstein
Gunnel Elisabeth Sunden
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO942230D0 publication Critical patent/NO942230D0/en
Publication of NO942230L publication Critical patent/NO942230L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Nye forbindelser av formelen: OCH, OM hvor R1 og R2, som er forskjellige, hver er metyl, -C(0)-CH3 eller -C(0)-OCH3 og hvorved en av R1 eller R2 alltid er metyl; og M er et fysiologisk akseptabelt motion, samt fremgangsmåter for fremstilling av disse forbindelsene, farmasøytiske preparater inneholdene forbindelsene som aktiv bestanddel og anvendelse av forbindelsene innen medisinen.New compounds of the formula: OCH, OM wherein R 1 and R 2 which are different are each methyl, -C (O) -CH 3 or -C (O) -OCH 3 and wherein one of R 1 or R 2 is always methyl; and M is a physiologically acceptable exercise, as well as methods for preparing these compounds, pharmaceutical compositions containing the compounds as active ingredient and the use of the compounds in medicine.

NO942230A 1991-12-19 1994-06-14 Substituted benzimidazoles, processes for their preparation and their use NO942230L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9103776A SE9103776D0 (en) 1991-12-19 1991-12-19 NEW COMPOUNDS
PCT/SE1992/000844 WO1993012124A1 (en) 1991-12-19 1992-12-08 Substituted benzimidazoles, process for their preparation as well as their use

Publications (2)

Publication Number Publication Date
NO942230D0 NO942230D0 (en) 1994-06-14
NO942230L true NO942230L (en) 1994-06-14

Family

ID=20384667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942230A NO942230L (en) 1991-12-19 1994-06-14 Substituted benzimidazoles, processes for their preparation and their use

Country Status (25)

Country Link
EP (1) EP0628049A1 (en)
JP (1) JPH07502503A (en)
KR (1) KR940703840A (en)
CN (1) CN1031827C (en)
AP (1) AP397A (en)
AU (1) AU665043B2 (en)
CA (1) CA2124689A1 (en)
CZ (1) CZ146794A3 (en)
FI (1) FI942912A7 (en)
HR (1) HRP921400A2 (en)
HU (1) HUT68270A (en)
IL (1) IL104025A0 (en)
IS (2) IS4079A (en)
MA (1) MA22746A1 (en)
MX (1) MX9207269A (en)
NO (1) NO942230L (en)
NZ (1) NZ246220A (en)
SE (1) SE9103776D0 (en)
SI (1) SI9200402A (en)
SK (1) SK73594A3 (en)
TN (1) TNSN92115A1 (en)
TW (1) TW224100B (en)
WO (1) WO1993012124A1 (en)
YU (1) YU101692A (en)
ZA (1) ZA928836B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19645974C1 (en) * 1996-11-07 1998-08-13 Andreas Johannes Kesel (Z) -5 - [[3-Hydroxy-2-methyl-5 - [(phosphonooxy) methyl] -4-pyridinyl] methylene] -2-thioxo-4-thiazolidinone, process for its preparation and use
EP1051181B1 (en) * 1997-12-31 2004-03-17 The University Of Kansas Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
WO2007014846A1 (en) 2005-07-28 2007-02-08 Intervet International B.V. Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
TWI385169B (en) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd Heterocyclic substituted pyridine derivatives and antifungal agent containing same
WO2007144362A1 (en) 2006-06-14 2007-12-21 Intervet International B.V. A suspension comprising benzimidazole carbamate and a polysorbate
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
US8513287B2 (en) * 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
MX365051B (en) * 2014-11-26 2019-05-09 Univ Mexico Nac Autonoma Novel hydrosoluble compounds derived from benzimidazole used in treating fasciolosis.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
SE8801907D0 (en) * 1988-05-20 1988-05-20 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
SE9002206D0 (en) * 1990-06-20 1990-06-20 Haessle Ab NEW COMPOUNDS
ATE184602T1 (en) * 1990-06-20 1999-10-15 Astra Ab DIALKOXYPYRIDINYLBENZIMIDAZOLE DERIVATIVES, PROCESS FOR PRODUCTION AND PHARMACEUTICAL USE THEREOF

Also Published As

Publication number Publication date
WO1993012124A1 (en) 1993-06-24
MA22746A1 (en) 1993-07-01
SE9103776D0 (en) 1991-12-19
NO942230D0 (en) 1994-06-14
CN1073446A (en) 1993-06-23
AU3175293A (en) 1993-07-19
AP9200463A0 (en) 1993-01-31
FI942912A0 (en) 1994-06-17
FI942912L (en) 1994-06-17
CA2124689A1 (en) 1993-06-24
YU101692A (en) 1995-10-03
SI9200402A (en) 1993-06-30
HRP921400A2 (en) 1994-08-31
EP0628049A1 (en) 1994-12-14
IS4079A (en) 1993-06-20
HU9401840D0 (en) 1994-09-28
AP397A (en) 1995-08-14
KR940703840A (en) 1994-12-12
CN1031827C (en) 1996-05-22
IL104025A0 (en) 1993-05-13
NZ246220A (en) 1996-02-27
MX9207269A (en) 1993-06-01
CZ146794A3 (en) 1996-02-14
TNSN92115A1 (en) 1993-06-08
FI942912A7 (en) 1994-06-17
ZA928836B (en) 1993-07-05
AU665043B2 (en) 1995-12-14
HUT68270A (en) 1995-06-28
JPH07502503A (en) 1995-03-16
TW224100B (en) 1994-05-21
SK73594A3 (en) 1995-02-08
IS3960A (en) 1993-06-20

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