NO941188L - Prevention of allograft repulsion by anti-adhesion molecules - Google Patents
Prevention of allograft repulsion by anti-adhesion moleculesInfo
- Publication number
- NO941188L NO941188L NO941188A NO941188A NO941188L NO 941188 L NO941188 L NO 941188L NO 941188 A NO941188 A NO 941188A NO 941188 A NO941188 A NO 941188A NO 941188 L NO941188 L NO 941188L
- Authority
- NO
- Norway
- Prior art keywords
- prevention
- adhesion molecules
- allograft
- antibodies
- treatment
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 102100022339 Integrin alpha-L Human genes 0.000 abstract 1
- 102000015271 Intercellular Adhesion Molecule-1 Human genes 0.000 abstract 1
- 108010064593 Intercellular Adhesion Molecule-1 Proteins 0.000 abstract 1
- 108010064548 Lymphocyte Function-Associated Antigen-1 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det tilveiebringes preparater og metoder for å forlenge funksjonen til et transplantert allograft og forhindre transplantat-frastotning. Spesielt fremkalles toleranse hos et mottager-pattedyr overfor et transplantert organ eller vev ved behandling med et preparat som omfatter mer enn en adhesjons-molekyl-inhibitor som omfatter antistoffer for adhesjonsmolekylet og tilsvarende ligand, f.eks. antistoffer for LFA-1 og ICAM-1. Preparatene ifølge oppfinnelsen kan videre anvendes for behandling av inflammatoriske reaksjoner, så vel som allergier og autoimmunsykdommer.Preparations and methods are provided to extend the function of a transplanted allograft and prevent graft rejection. In particular, tolerance of a recipient mammal to a transplanted organ or tissue is induced by treatment with a composition comprising more than one adhesion molecule inhibitor comprising antibodies to the adhesion molecule and corresponding ligand, e.g. antibodies for LFA-1 and ICAM-1. The compositions of the invention can further be used for the treatment of inflammatory reactions, as well as allergies and autoimmune diseases.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76804491A | 1991-10-01 | 1991-10-01 | |
| PCT/US1992/008279 WO1993006864A1 (en) | 1991-10-01 | 1992-09-29 | Preventing allograft rejection with antibodies to adhesion molecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO941188D0 NO941188D0 (en) | 1994-03-30 |
| NO941188L true NO941188L (en) | 1994-05-31 |
Family
ID=26785050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO941188A NO941188L (en) | 1991-10-01 | 1994-03-30 | Prevention of allograft repulsion by anti-adhesion molecules |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO941188L (en) |
-
1994
- 1994-03-30 NO NO941188A patent/NO941188L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO941188D0 (en) | 1994-03-30 |
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