NO941152L - Sykliske adhesjonsinhibitorer - Google Patents

Sykliske adhesjonsinhibitorer

Info

Publication number: NO941152L
Authority: NO; Norway
Prior art keywords: lys; alanine; asp; atoms; prodn
Prior art date: 1993-04-01

Application number

NO941152A

Other languages

English (en)

Other versions

NO941152D0 (no

NO313756B1 (no

Inventor

Alfred Jonczyk

Gunter Holzemann

Brunhilde Felding-Habermann

Friedrich Rippmann

Beate Diefenbach

Horst Kessler

Roland Haubner

Jochen Wermuth

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-01

Filing date

1994-03-29

Publication date

1994-10-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6484433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO941152(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-03-29 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1994-03-29 Publication of NO941152D0 publication Critical patent/NO941152D0/no

1994-10-03 Publication of NO941152L publication Critical patent/NO941152L/no

2002-11-25 Publication of NO313756B1 publication Critical patent/NO313756B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Zoology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Physical Education & Sports Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Pyrane Compounds (AREA)

NO19941152A 1993-04-01 1994-03-29 Syklopeptidforbindelser, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstillingderav, samt anvdendelse av forbindelsene til fremstilling avmedikamenter og immobiliserte ligander, og til rensing av integr NO313756B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4310643A DE4310643A1 (de)	1993-04-01	1993-04-01	Cyclische Adhäsionsinhibitoren

Publications (3)

Publication Number	Publication Date
NO941152D0 NO941152D0 (no)	1994-03-29
NO941152L true NO941152L (no)	1994-10-03
NO313756B1 NO313756B1 (no)	2002-11-25

Family

ID=6484433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19941152A NO313756B1 (no)	1993-04-01	1994-03-29	Syklopeptidforbindelser, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstillingderav, samt anvdendelse av forbindelsene til fremstilling avmedikamenter og immobiliserte ligander, og til rensing av integr

Country Status (20)

Country	Link
US (2)	US5849692A (no)
EP (1)	EP0632053B1 (no)
JP (1)	JP3694332B2 (no)
KR (1)	KR100304201B1 (no)
CN (1)	CN1056851C (no)
AT (1)	ATE184288T1 (no)
AU (1)	AU684489B2 (no)
CA (1)	CA2120303C (no)
CZ (1)	CZ286768B6 (no)
DE (2)	DE4310643A1 (no)
DK (1)	DK0632053T3 (no)
ES (1)	ES2138632T3 (no)
GR (1)	GR3032074T3 (no)
HU (1)	HUT69726A (no)
NO (1)	NO313756B1 (no)
PL (1)	PL178791B1 (no)
RU (1)	RU2130030C1 (no)
SK (1)	SK281828B6 (no)
TW (1)	TW343198B (no)
UA (1)	UA34436C2 (no)

Families Citing this family (45)

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US5753230A (en)	1994-03-18	1998-05-19	The Scripps Research Institute	Methods and compositions useful for inhibition of angiogenesis
DE4415310A1 (de) *	1994-04-30	1995-11-02	Merck Patent Gmbh	Cyclopeptide
US7053041B1 (en)	1996-05-31	2006-05-30	The Scripps Research Institute	Methods and compositions useful for inhibition of αvβ5mediated angiogenesis
DE19534016A1 (de) *	1995-09-14	1997-03-20	Merck Patent Gmbh	Biotinderivate
DE19534177A1 (de) *	1995-09-15	1997-03-20	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
DE19538741A1 (de) *	1995-10-18	1997-04-24	Merck Patent Gmbh	Cyclopeptidderivate
DE19613933A1 (de) *	1996-04-06	1997-10-09	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
RU2194528C2 (ru)	1996-05-31	2002-12-20	Дзе Скриппс Рисерч Инститьют	Способы и композиции, используемые для ингибирования ангиогенеза
DE19736772A1 (de) *	1997-08-23	1999-02-25	Merck Patent Gmbh	Cyclopeptidderivate
DE19842415A1 (de) *	1998-09-16	2000-03-23	Merck Patent Gmbh	Pharmazeutische Zubereitung
PL350291A1 (en)	1998-12-23	2002-12-02	Searle & Co	Method of using a cyclooxygenase-2 inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
UA71608C2 (en)	1999-03-11	2004-12-15	Merck Patent Gmbh	A method for producing the cyclic pentapeptide
DE19933173A1 (de)	1999-07-15	2001-01-18	Merck Patent Gmbh	Cyclische Peptidderivate als Inhibitoren des Integrins alpha¶v¶beta¶6¶
US6359015B1 (en)	2000-02-28	2002-03-19	The United States Of America As Represented By The Department Of Veterans Affairs	Method for antagonizing inhibition effects of alcohol on cell adhesion
US6624187B1 (en) *	2000-06-12	2003-09-23	Health Research, Inc.	Long wave length absorbing bacteriochlorin alkyl ether analogs
DE10040105A1 (de)	2000-08-17	2002-02-28	Merck Patent Gmbh	Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften
FR2814744B1 (fr) *	2000-10-04	2002-11-29	Commissariat Energie Atomique	Cyclopeptides, leur procede de preparation et leur utilisation comme inhibiteur ou activateur de l'angiogenese
IL157706A0 (en) *	2001-03-02	2004-03-28	Medimmune Inc	METHODS OF PREVENTING OR TREATING INFLAMMATORY OR AUTOIMMUNE DISORDERS BY ADMINISTERING INTEGRIN alphav beta3 ANTAGONISTS
US7879267B2 (en) *	2001-08-02	2011-02-01	J&J Vision Care, Inc.	Method for coating articles by mold transfer
RU2214416C2 (ru) *	2001-12-10	2003-10-20	Государственный научный центр вирусологии и биотехнологии "Вектор"	Rgd-содержащие пептиды
EP1487492A4 (en) *	2002-03-04	2008-10-01	Medimmune Inc	PREVENTION OR TREATMENT OF CANCER WITH INTEGRIN ALPHAVBETA3 ANTAGONISTS IN COMBINATION WITH OTHER MEDICINES
EP1487489A4 (en) *	2002-03-04	2008-10-01	Medimmune Inc	METHOD FOR PREVENTING OR TREATING ILLNESSES BY ADMINISTERING AN INTEGRIN AVB3 ANTAGONIST IN COMBINATION WITH AN HMG-CoA REDUCTASE INHIBITOR OR A BISPHOSPHONATE
US7371383B2 (en)	2002-04-12	2008-05-13	Medimmune, Inc.	Recombinant anti-interleukin-9 antibodies
GB0217017D0 (en) *	2002-07-23	2002-08-28	Bioacta Ltd	Peptide 2
ITRM20020402A1 (it) *	2002-07-29	2004-01-29	Sigma Tau Ind Farmaceuti	Derivati fluoro-alchil-ciclopeptidi ad attivita' anti-integrine.
US6977272B2 (en) *	2002-10-16	2005-12-20	President And Fellows Of Harvard College	Method for antagonizing inhibition effects of alcohol on cell adhesion
WO2004066956A2 (en) *	2003-01-30	2004-08-12	Medimmune, Inc.	Uses of integrin alphavbeta3 antagonists
WO2004091510A2 (en) *	2003-04-11	2004-10-28	Medimmune, Inc.	Recombinant il-9 antibodies and uses thereof
US7351739B2 (en) *	2004-04-30	2008-04-01	Wellgen, Inc.	Bioactive compounds and methods of uses thereof
ITRM20040239A1 (it) *	2004-05-13	2004-08-13	Sigma Tau Ind Farmaceuti	Derivati ciclopeptidici ad attivita' antintegrine.
EP1809326A4 (en)	2004-10-27	2009-11-04	Medimmune Inc	MODULATION OF ANTIBODY SPECIFICITY BY MEASURING ADAPTATION OF ITS AFFINITY TO AN APPARENT ANTIGEN
CA2657581A1 (en)	2006-07-11	2008-01-17	Roy C. Levitt	Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
ES2766770T3 (es)	2006-08-10	2020-06-15	Roy C Levitt	Anakinra para uso en el tratamiento del síndrome de bronquiolitis obliterante
CN101627049B (zh)	2006-11-10	2012-09-05	卡拉治疗学股份有限公司	合成酞酰胺
US8236766B2 (en)	2006-11-10	2012-08-07	Cara Therapeutics, Inc.	Uses of synthetic peptide amides
US7713937B2 (en)	2006-11-10	2010-05-11	Cara Therapeutics, Inc.	Synthetic peptide amides and dimeric forms thereof
US7842662B2 (en)	2006-11-10	2010-11-30	Cara Therapeutics, Inc.	Synthetic peptide amide dimers
US8906859B2 (en)	2006-11-10	2014-12-09	Cera Therapeutics, Inc.	Uses of kappa opioid synthetic peptide amides
JP5647972B2 (ja) *	2008-04-08	2015-01-07	メルクパテントゲゼルシャフトミットベシュレンクテルハフツングＭｅｒｃｋＰａｔｅｎｔＧｅｓｅｌｌｓｃｈａｆｔｍｉｔｂｅｓｃｈｒａｅｎｋｔｅｒＨａｆｔｕｎｇ	環状ペプチドを含む組成物および使用方法
MX2011004252A (es) *	2008-10-23	2012-01-27	Steba Biotech N V	Peptidomiméticos que contienen arginina-glicina-ácido aspártato y usos de los mismos.
CN101906141B (zh) *	2009-06-02	2013-04-17	首都医科大学	一类肽链与双脂肪醇链的偶联物及其制备方法和应用
CN101906144B (zh) *	2009-06-03	2013-06-19	首都医科大学	一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
RU2626002C1 (ru)	2016-10-24	2017-07-21	Общество С Ограниченной Ответственностью "Айвикс"	Новая группа пептидов для лечения женской сексуальной дисфункции
RU2655763C2 (ru) *	2016-10-24	2018-05-29	Общество С Ограниченной Ответственностью "Айвикс"	Фармацевтическая композиция и способ лечения женских сексуальных дисфункций
US10494403B2 (en)	2018-03-06	2019-12-03	Ciphore Biomed Technology Limited Company	Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4328214A (en) *	1979-07-04	1982-05-04	Ciba-Geigy Corporation	Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
US4472305A (en) *	1983-05-17	1984-09-18	Sterling Drug Inc.	Hexapeptide amides
GB8903804D0 (en) *	1989-02-20	1989-04-05	Sandoz Ltd	Improvements in or relating to organic compounds
EP0358418B1 (en) *	1988-09-05	1992-12-16	Sankyo Company Limited	Cyclic peptide, its preparation and its use in the treatment of cardiovascular disorders
JP2945680B2 (ja) *	1988-09-09	1999-09-06	旭硝子株式会社	ペプチド誘導体およびその用途
US5192746A (en) *	1990-07-09	1993-03-09	Tanabe Seiyaku Co., Ltd.	Cyclic cell adhesion modulation compounds
HUT63609A (en) *	1992-03-10	1993-09-28	Sandoz Ag	Process for producing new derivatives and isosters of beta-amino acids and pharmaceutical compositions comprising such compounds
UA43823C2 (uk) *	1992-07-06	2002-01-15	Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг	ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
DE4237456A1 (de) *	1992-11-06	1994-05-11	Merck Patent Gmbh	Cyclopeptide
US5753230A (en) *	1994-03-18	1998-05-19	The Scripps Research Institute	Methods and compositions useful for inhibition of angiogenesis

1993
- 1993-04-01 DE DE4310643A patent/DE4310643A1/de not_active Withdrawn
1994
- 1994-03-02 UA UA94005107A patent/UA34436C2/uk unknown
- 1994-03-21 ES ES94104396T patent/ES2138632T3/es not_active Expired - Lifetime
- 1994-03-21 EP EP94104396A patent/EP0632053B1/de not_active Expired - Lifetime
- 1994-03-21 DE DE59408715T patent/DE59408715D1/de not_active Expired - Lifetime
- 1994-03-21 DK DK94104396T patent/DK0632053T3/da active
- 1994-03-21 AT AT94104396T patent/ATE184288T1/de active
- 1994-03-25 CZ CZ1994704A patent/CZ286768B6/cs not_active IP Right Cessation
- 1994-03-29 NO NO19941152A patent/NO313756B1/no not_active IP Right Cessation
- 1994-03-30 AU AU59185/94A patent/AU684489B2/en not_active Expired
- 1994-03-30 TW TW083102761A patent/TW343198B/zh active
- 1994-03-30 CN CN94103298A patent/CN1056851C/zh not_active Expired - Lifetime
- 1994-03-30 CA CA002120303A patent/CA2120303C/en not_active Expired - Lifetime
- 1994-03-31 KR KR1019940006639A patent/KR100304201B1/ko not_active Expired - Lifetime
- 1994-03-31 PL PL94302854A patent/PL178791B1/pl unknown
- 1994-03-31 SK SK383-94A patent/SK281828B6/sk unknown
- 1994-03-31 JP JP09682994A patent/JP3694332B2/ja not_active Expired - Lifetime
- 1994-03-31 RU RU94011276A patent/RU2130030C1/ru active
- 1994-03-31 HU HU9400937A patent/HUT69726A/hu unknown
1996
- 1996-03-15 US US08/616,770 patent/US5849692A/en not_active Expired - Lifetime
1998
- 1998-10-01 US US09/164,585 patent/US6169072B1/en not_active Expired - Lifetime
1999
- 1999-12-08 GR GR990403165T patent/GR3032074T3/el unknown

Also Published As

Publication number	Publication date
AU5918594A (en)	1994-10-06
SK38394A3 (en)	1995-02-08
ATE184288T1 (de)	1999-09-15
HUT69726A (en)	1995-09-28
ES2138632T3 (es)	2000-01-16
NO941152D0 (no)	1994-03-29
US5849692A (en)	1998-12-15
JPH06329698A (ja)	1994-11-29
RU2130030C1 (ru)	1999-05-10
TW343198B (en)	1998-10-21
EP0632053A3 (de)	1995-02-15
NO313756B1 (no)	2002-11-25
DK0632053T3 (da)	2000-03-13
US6169072B1 (en)	2001-01-02
CN1056851C (zh)	2000-09-27
HU9400937D0 (en)	1994-06-28
CA2120303A1 (en)	1994-10-02
UA34436C2 (uk)	2001-03-15
EP0632053B1 (de)	1999-09-08
CZ286768B6 (en)	2000-07-12
DE59408715D1 (de)	1999-10-14
CZ70494A3 (en)	1995-01-18
KR100304201B1 (ko)	2001-11-30
PL178791B1 (pl)	2000-06-30
EP0632053A2 (de)	1995-01-04
JP3694332B2 (ja)	2005-09-14
GR3032074T3 (en)	2000-03-31
AU684489B2 (en)	1997-12-18
CA2120303C (en)	2007-05-01
DE4310643A1 (de)	1994-10-06
CN1099760A (zh)	1995-03-08
SK281828B6 (sk)	2001-08-06

Publication	Publication Date	Title
DE59408715D1 (de)	1999-10-14	Cyclische Adhäsionsinhibitoren
CA1315479C (en)	1993-03-30	Platelet-aggregation inhibitor peptide derivatives
US5023233A (en)	1991-06-11	Fibrinogen receptor antagonists
ES2144179T3 (es)	2000-06-01	Inhibidores de adhesion ciclicos.
US5061693A (en)	1991-10-29	Fibrinogen receptor antagonists
EP0410540A1 (en)	1991-01-30	Fibrinogen receptor antagonists
CA2027315A1 (en)	1991-04-14	Fibrinogen receptor antagonists
EP0410541A1 (en)	1991-01-30	Fibrinogen receptor antagonists
FR2591485B1 (fr)	1989-07-28	Compositions stabilisees contenant l'activateur du plasminogene du tissu humain.
KR930007972A (ko)	1993-05-20	환상 혈관활성 펩티드
KR920009846A (ko)	1992-06-25	시클로펩티드
DK0585397T3 (da)	1997-08-25	Bombesinanaloger
KR880001696A (ko)	1988-04-26	레닌 억제용 디- 및 트리 펩타이드 및 이의 제조방법
DK0393934T3 (da)	1994-11-21	Nye peptider samt antidemensmidler indeholdende disse peptider
NO941151L (no)	1994-10-03	Lineære adhesjonsinhibitorer
NO983177L (no)	1998-07-10	Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
DK1309613T3 (da)	2008-08-11	Farmaceutisk præparat omfattende et analgetisk peptid
EP0182627A3 (en)	1988-10-05	Basic v1-vasopressin antagonists
EP0796867A4 (en)	1999-10-20	Peptide, bronchodilator and blood flow ameliorant
NO975565L (no)	1998-01-19	Benstimulerende faktor
ES8701784A1 (es)	1986-12-01	Un procedimiento para preparar un peptido ciclico con acti- vidad antagonista de vasopresina
KR940011479A (ko)	1994-06-21	시클로 펩티드
YU48997A (sh)	1999-09-27	Novi biološki aktivni proteini, njihove farmaceutske smeše i postupak za njihovo dobijanje
DK0552106T3 (da)	1996-06-24	Peptider med antagonistaktivitet over for bradykinin
KR960703612A (ko)	1996-08-31	면역계 및 중추 신경계 치료용 신규의 트리펩티드(novel tripeptides useful in immune and cns therapy)

Legal Events

Date	Code	Title	Description
2004-12-27	MM1K	Lapsed by not paying the annual fees