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NO940711D0 - Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging - Google Patents

Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging

Info

Publication number
NO940711D0
NO940711D0 NO940711A NO940711A NO940711D0 NO 940711 D0 NO940711 D0 NO 940711D0 NO 940711 A NO940711 A NO 940711A NO 940711 A NO940711 A NO 940711A NO 940711 D0 NO940711 D0 NO 940711D0
Authority
NO
Norway
Prior art keywords
preparation
gas
contrast agents
diagnostic imaging
filled microcapsules
Prior art date
Application number
NO940711A
Other languages
English (en)
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Priority to NO940711A priority Critical patent/NO940711D0/no
Publication of NO940711D0 publication Critical patent/NO940711D0/no
Priority to PCT/GB1995/000437 priority patent/WO1995023615A1/en
Priority to EP95909883A priority patent/EP0748227A1/en
Priority to JP7522764A priority patent/JPH09509612A/ja
Priority to AU18186/95A priority patent/AU1818695A/en
Priority to NO963617A priority patent/NO963617L/no
Priority to US09/005,758 priority patent/US6110444A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
NO940711A 1994-03-01 1994-03-01 Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging NO940711D0 (no)

Priority Applications (7)

Application Number Priority Date Filing Date Title
NO940711A NO940711D0 (no) 1994-03-01 1994-03-01 Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
PCT/GB1995/000437 WO1995023615A1 (en) 1994-03-01 1995-03-01 Gas-containing microcapsules useful as contrast agents for diagnostic imaging
EP95909883A EP0748227A1 (en) 1994-03-01 1995-03-01 Gas-containing microcapsules useful as contrast agents for diagnostic imaging
JP7522764A JPH09509612A (ja) 1994-03-01 1995-03-01 画像診断用造影剤として有用な気体含有微小カプセル
AU18186/95A AU1818695A (en) 1994-03-01 1995-03-01 Gas-containing microcapsules useful as contrast agents for diagnostic imaging
NO963617A NO963617L (no) 1994-03-01 1996-08-29 Gassfylte mikrokapsler til bruk som kontrastmidler
US09/005,758 US6110444A (en) 1994-03-01 1998-01-12 Gas-containing microcapsules useful as contrast agents for diagnostic imaging

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO940711A NO940711D0 (no) 1994-03-01 1994-03-01 Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging

Publications (1)

Publication Number Publication Date
NO940711D0 true NO940711D0 (no) 1994-03-01

Family

ID=19896882

Family Applications (2)

Application Number Title Priority Date Filing Date
NO940711A NO940711D0 (no) 1994-03-01 1994-03-01 Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
NO963617A NO963617L (no) 1994-03-01 1996-08-29 Gassfylte mikrokapsler til bruk som kontrastmidler

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO963617A NO963617L (no) 1994-03-01 1996-08-29 Gassfylte mikrokapsler til bruk som kontrastmidler

Country Status (6)

Country Link
US (1) US6110444A (no)
EP (1) EP0748227A1 (no)
JP (1) JPH09509612A (no)
AU (1) AU1818695A (no)
NO (2) NO940711D0 (no)
WO (1) WO1995023615A1 (no)

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US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5695740A (en) * 1993-05-12 1997-12-09 The Board Of Regents Of The University Of Nebraska Perfluorocarbon ultrasound contrast agent comprising microbubbles containing a filmogenic protein and a saccharide
US5701899A (en) * 1993-05-12 1997-12-30 The Board Of Regents Of The University Of Nebraska Perfluorobutane ultrasound contrast agent and methods for its manufacture and use
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US5736121A (en) * 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
US5560364A (en) * 1995-05-12 1996-10-01 The Board Of Regents Of The University Of Nebraska Suspended ultra-sound induced microbubble cavitation imaging
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US5648098A (en) * 1995-10-17 1997-07-15 The Board Of Regents Of The University Of Nebraska Thrombolytic agents and methods of treatment for thrombosis
WO1997022409A1 (en) * 1995-12-21 1997-06-26 Drexel University Hollow polymer microcapsules and method of producing
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
US6245747B1 (en) 1996-03-12 2001-06-12 The Board Of Regents Of The University Of Nebraska Targeted site specific antisense oligodeoxynucleotide delivery method
ATE345682T1 (de) 1996-05-01 2006-12-15 Imarx Pharmaceutical Corp In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
US5976501A (en) * 1996-06-07 1999-11-02 Molecular Biosystems, Inc. Use of pressure resistant protein microspheres encapsulating gases as ultrasonic imaging agents for vascular perfusion
US5849727A (en) * 1996-06-28 1998-12-15 Board Of Regents Of The University Of Nebraska Compositions and methods for altering the biodistribution of biological agents
DE19626530A1 (de) * 1996-07-02 1998-01-15 Byk Gulden Lomberg Chem Fab MR-Kontrastmittelzubereitungen
AU3665297A (en) * 1996-07-19 1998-02-10 Sonus Pharmaceuticals, Inc. Enhanced ultrasound contrast imaging using inhaled gases
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US6083484A (en) * 1996-10-17 2000-07-04 Molecular Biosystems, Inc. Microparticles stabilized by polynuclear chromium complexes and their use as ultrasound contrast agents
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US6045777A (en) * 1997-06-30 2000-04-04 Acusphere, Inc. Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
GB9808599D0 (en) * 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or realting to contrast agents
ES2292250T5 (es) * 1998-07-15 2010-09-14 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Envolventes de polielectrolitos sobre plantillas (templates) biologicas.
DE19925311B4 (de) * 1999-05-27 2004-06-09 Schering Ag Mehrstufen-Verfahren zur Herstellung von gasgefüllten Mikrokapseln
ES2184716T3 (es) * 1999-06-10 2003-04-16 Max Planck Gesellschaft Encapsulacion de cristales por medio de recubrimientos multicapa.
US6439236B1 (en) 1999-10-25 2002-08-27 The Board Of Regents Of The University Of Nebraska Methods for inducing atrial and ventricular rhythms using ultrasound and microbubbles
AU2001246440A1 (en) * 2000-02-29 2001-09-12 Rainer Pommersheim Microcapsule, in particular, for immobilizing organic or inorganic solids, liquids and/or gases
US6492025B1 (en) 2000-11-27 2002-12-10 Xerox Corporation Microcapsule composition
US6488870B1 (en) 2000-11-27 2002-12-03 Xerox Corporation Encapsulation process
JP4586159B2 (ja) * 2000-12-31 2010-11-24 国立大学法人 鹿児島大学 マイクロカプセルによるｘ線回折造影装置
GB0120645D0 (en) 2001-08-24 2001-10-17 Smiths Group Plc Medico-surgical devices
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
GB0307350D0 (en) 2003-03-29 2003-05-07 Smiths Group Plc Catheters
US20050074406A1 (en) * 2003-10-03 2005-04-07 Scimed Life Systems, Inc. Ultrasound coating for enhancing visualization of medical device in ultrasound images
JP4527962B2 (ja) * 2003-10-31 2010-08-18 トッパン・フォームズ株式会社 マイクロカプセル含有油性インキの製造方法
EP1701745B1 (en) * 2003-12-22 2014-12-10 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
US20070081946A1 (en) * 2003-12-22 2007-04-12 Bracco Research S.A. Assembly of gas-filled microvesicle with active component for contrast imaging
US20080019904A1 (en) * 2004-06-29 2008-01-24 Koninklijke Philips Electronics, N.V. System For Manufacturing Micro-Sheres
AU2005273865B2 (en) 2004-08-18 2011-02-24 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US8123693B2 (en) 2005-06-20 2012-02-28 Conceptus, Inc. Methods and devices for determining lumen occlusion
JP6250262B2 (ja) * 2009-02-09 2017-12-20 セルテック・アクチボラゲットＣｅｌｌｕｔｅｃｈ Ａｂ ポリマーシェル
US10258563B2 (en) 2009-04-20 2019-04-16 Drexel University Encapsulation of microbubbles within the aqueous core of microcapsules
WO2011025893A1 (en) * 2009-08-28 2011-03-03 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for production of gas-filled microbubbles
US8585616B2 (en) 2009-10-09 2013-11-19 Conceptus, Inc. Methods and apparatus for determining fallopian tube occlusion
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
EP2545908A1 (en) * 2011-07-11 2013-01-16 RWTH Aachen Medium for microbubbles or microparticles and preparation thereof
US20130072854A1 (en) 2011-09-19 2013-03-21 General Electric Company Microbubble complexes and methods of use
KR20240005184A (ko) 2014-12-31 2024-01-11 랜티우스 메디컬 이메징, 인크. 지질-캡슐화된 기체 마이크로스피어 조성물 및 관련 방법
JP2019515936A (ja) 2016-05-04 2019-06-13 ランセウス メディカル イメージング， インコーポレイテッド 超音波造影剤を調製するための方法およびデバイス
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
CN112642371A (zh) * 2020-12-10 2021-04-13 东南大学 一种基于气泡法薄壁大尺度软性微胶囊的制备方法
DE102022120500B3 (de) * 2022-08-15 2023-10-12 FILK Freiberg Institute gGmbH Verfahren und Vorrichtung zur Herstellung von Hohlkugeln aus Kollagen und Kollagenderivaten und Hohlkugeln aus Kollagen und Gelatine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2504825B2 (ja) * 1989-03-31 1996-06-05 三田工業株式会社 マイクロカプセルトナ−
GB9003821D0 (en) * 1990-02-20 1990-04-18 Danbiosyst Uk Diagnostic aid
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
GB9116610D0 (en) * 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
US5718884A (en) * 1992-09-16 1998-02-17 Nycomed Imaging As Microbubble-based contrast agents with crosslinked and reduced proteinaceous shells
US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell

Also Published As

Publication number Publication date
AU1818695A (en) 1995-09-18
NO963617D0 (no) 1996-08-29
NO963617L (no) 1996-10-31
EP0748227A1 (en) 1996-12-18
WO1995023615A1 (en) 1995-09-08
US6110444A (en) 2000-08-29
JPH09509612A (ja) 1997-09-30

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