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NO931766D0 - Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin - Google Patents

Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin

Info

Publication number
NO931766D0
NO931766D0 NO931766A NO931766A NO931766D0 NO 931766 D0 NO931766 D0 NO 931766D0 NO 931766 A NO931766 A NO 931766A NO 931766 A NO931766 A NO 931766A NO 931766 D0 NO931766 D0 NO 931766D0
Authority
NO
Norway
Prior art keywords
morphine
transdermal delivery
preservant
pct
topical preparations
Prior art date
Application number
NO931766A
Other languages
English (en)
Other versions
NO931766L (no
Inventor
Hans Bundgaard
Lona Christrup
Joern Drustrup
Ann Fullerton
Martin Nicklasson
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of NO931766D0 publication Critical patent/NO931766D0/no
Publication of NO931766L publication Critical patent/NO931766L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO93931766A 1990-11-16 1993-05-14 Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin NO931766L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9003665A SE9003665D0 (sv) 1990-11-16 1990-11-16 Morphine prodrugs
PCT/SE1991/000760 WO1992008459A1 (en) 1990-11-16 1991-11-11 Topical compositions for transdermal delivery of produg derivatives of morphine

Publications (2)

Publication Number Publication Date
NO931766D0 true NO931766D0 (no) 1993-05-14
NO931766L NO931766L (no) 1993-05-14

Family

ID=20380936

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93931766A NO931766L (no) 1990-11-16 1993-05-14 Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin

Country Status (18)

Country Link
US (1) US5908846A (no)
EP (1) EP0557385B1 (no)
JP (1) JP3493434B2 (no)
AT (1) ATE168560T1 (no)
AU (1) AU655612B2 (no)
CA (1) CA2095223C (no)
DE (1) DE69129861T2 (no)
DK (1) DK0557385T3 (no)
ES (1) ES2121793T3 (no)
FI (1) FI932212L (no)
IE (1) IE913682A1 (no)
IL (1) IL99905A (no)
NO (1) NO931766L (no)
NZ (1) NZ240349A (no)
PT (1) PT99513B (no)
SE (1) SE9003665D0 (no)
WO (1) WO1992008459A1 (no)
ZA (1) ZA918512B (no)

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US5607691A (en) * 1992-06-12 1997-03-04 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
DE4403709A1 (de) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid
JPH07267862A (ja) * 1994-03-29 1995-10-17 Sekisui Chem Co Ltd 経皮吸収貼付剤
WO1996028451A1 (en) * 1995-03-14 1996-09-19 Euroceltique S.A. Morphine-3-esters
DE19508664C2 (de) * 1995-03-14 2001-08-23 Christian Mignat Verwendung von Morphin-3-estern, Morphin-3-ester als solche und Verfahren zu deren Herstellung
GB9519363D0 (en) 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
DE19602959A1 (de) * 1995-12-20 1997-07-31 Nycomed Arzneimittel Gmbh Neue Morphinderivate, Verfahren zu deren Herstellung und deren Verwendung
DE19923551A1 (de) * 1999-05-21 2000-11-30 Lohmann Therapie Syst Lts Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht
RU2230556C2 (ru) 1999-10-29 2004-06-20 Эро-Селтик, С.А. Препаративные формы гидрокодона с контролируемым высвобождением
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
HU230875B1 (hu) 2000-10-30 2018-11-29 Euro-Celtique S.A. Szabályozott hatóanyag-leadású hidrokodon készítmények
US6569449B1 (en) * 2000-11-13 2003-05-27 University Of Kentucky Research Foundation Transdermal delivery of opioid antagonist prodrugs
US20040097472A1 (en) * 2000-11-14 2004-05-20 West Simon Michael Complexes of phosphate derivatives
AUPR549901A0 (en) * 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
JP4814486B2 (ja) * 2001-06-05 2011-11-16 シヴィダ・インコーポレイテッド 持続放出性鎮痛性化合物
JP4745608B2 (ja) * 2001-07-27 2011-08-10 バイタル ヘルス サイエンシズ プロプライアタリー リミティド 電子伝達剤のリン酸誘導体を用いた皮膚治療
WO2003049774A1 (en) * 2001-12-13 2003-06-19 Vital Health Sciences Pty Ltd Transdermal transport of compounds
AU2002950713A0 (en) * 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
EP1554290B1 (en) * 2002-10-25 2009-09-30 Euro-Celtique S.A. Analogs and prodrugs of buprenorphine
AU2003285200A1 (en) * 2002-11-09 2004-06-03 Nobex Corporation Modified carbamate-containing prodrugs and methods of synthesizing same
JP4690305B2 (ja) * 2003-01-17 2011-06-01 バイタル ヘルス サイエンシズ プロプライアタリー リミティド 抗増殖性質を有する化合物
AU2003901815A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphate derivatives
NZ594154A (en) * 2003-07-25 2012-12-21 Euro Celtique Sa Transdermal administration of buprenorphine for preoperative treatment of post operative pain
UA88646C2 (uk) * 2004-02-06 2009-11-10 Евро-Селтик С.А. Способи одержання 3-о-захищених морфінонів і 3-о-захищених морфінондієнолкарбоксилатів, а також композиція для окислення спирту до кетону
EP2351555B1 (en) 2004-02-23 2016-10-05 Euro-Celtique S.A. Abuse resistance opioid transdermal delivery device
NZ549567A (en) 2004-03-03 2009-10-30 Vital Health Sciences Pty Ltd Formulations comprising a tocopheryl phosphate tertiary amine alkaloid complex
ES2557475T3 (es) 2005-06-17 2016-01-26 Vital Health Sciences Pty Ltd. Un portador que comprende uno o más derivados di- y/o monofosfato de agentes de transferencia de electrones
WO2007070981A1 (en) * 2005-12-23 2007-06-28 Vital Health Sciences Pty Ltd Compounds having cytokine modulating properties
ES2591278T3 (es) 2007-03-02 2016-11-25 Teika Pharmaceutical Co., Ltd. Composición medicinal para absorción transdérmica, unidad de almacenamiento de composición medicinal y preparación para absorción transdérmica que usa la misma
US9511016B2 (en) * 2007-06-12 2016-12-06 Epicentrx, Inc. Topical composition for treating pain
US8354116B2 (en) * 2007-06-18 2013-01-15 Biochemics, Inc. Bifunctional synthetic molecules
US20090130048A1 (en) * 2007-11-19 2009-05-21 Oronsky Bryan Todd Topical Composition for Treating Pain
US8784872B2 (en) 2007-11-19 2014-07-22 Comgenrx, Inc. Formulation for decreasing tobacco, alcohol, drug or food consumption
WO2009158667A2 (en) * 2008-06-27 2009-12-30 Comgenrx, Inc. Povidone compositions for wound healing
UA102916C2 (uk) 2009-07-02 2013-08-27 Кемфарм, Інк. Композиція на основі кон'югату гідрокодону з бензойною кислотою, похідними бензойної кислоти або гетероарилкарбоновою кислотою, проліки, спосіб лікування від зловживань
US10849981B2 (en) 2009-07-02 2020-12-01 KemPham, Inc. Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
WO2011002995A1 (en) * 2009-07-02 2011-01-06 Kempharm, Inc. Phenylethanoic acid, phenylpropanoic acid and phenylpropenoic acid conjugates and prodrugs of hydrocodone, methods of making and use thereof
US10071030B2 (en) 2010-02-05 2018-09-11 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
CN107115326B (zh) 2010-04-13 2021-01-22 雷尔玛达治疗股份有限公司 1-甲基-n-(2,6-二甲苯基)-2-哌啶甲酰胺的皮肤用药物组合物及其使用方法
TWI520732B (zh) 2011-01-18 2016-02-11 輝瑞有限公司 固體分子分散液
EP2685992A4 (en) 2011-03-15 2014-09-10 Phosphagenics Ltd AMINOCHINOLINE AS A KINASEHEMMER
KR101976101B1 (ko) 2014-11-25 2019-05-09 켐팜 인코포레이티드 옥시코돈의 벤조산, 벤조산 유도체 및 헤테로아릴 카르복실산 콘쥬게이트
ES2981002T3 (es) 2015-12-09 2024-10-04 Avecho Biotechnology Ltd Formulación farmacéutica
JP7198754B2 (ja) 2016-12-21 2023-01-04 アベーチョ バイオテクノロジー リミテッド 方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
US4940586A (en) * 1987-02-26 1990-07-10 Alza Corporation Skin permeation enhancer compositions using sucrose esters
US4879297A (en) * 1987-06-01 1989-11-07 Warner-Lambert Company Fatty acids and their small chain esters as penetration enhancers in aqueous systems
US4891377A (en) * 1988-12-02 1990-01-02 Board Of Regents Acting For And On Behalf Of University Of Michigan Transdermal delivery of the narcotic analgesics etorphine and analogs
US5240932A (en) * 1990-03-30 1993-08-31 Yasunori Morimoto Percutaneously absorbable compositions of morphine or analogous analgesics of morphine
US5069909A (en) * 1990-06-20 1991-12-03 Cygnus Therapeutic Systems Transdermal administration of buprenorphine

Also Published As

Publication number Publication date
US5908846A (en) 1999-06-01
JPH06502422A (ja) 1994-03-17
WO1992008459A1 (en) 1992-05-29
CA2095223C (en) 2002-12-17
DE69129861D1 (de) 1998-08-27
ATE168560T1 (de) 1998-08-15
NZ240349A (en) 1993-07-27
DK0557385T3 (da) 1999-04-26
IE913682A1 (en) 1992-05-20
PT99513B (pt) 1999-04-30
AU8938191A (en) 1992-06-11
DE69129861T2 (de) 1999-04-01
SE9003665D0 (sv) 1990-11-16
IL99905A (en) 1995-06-29
CA2095223A1 (en) 1992-05-17
FI932212A7 (fi) 1993-05-14
FI932212A0 (fi) 1993-05-14
EP0557385A1 (en) 1993-09-01
EP0557385B1 (en) 1998-07-22
ZA918512B (en) 1992-08-26
PT99513A (pt) 1992-09-30
ES2121793T3 (es) 1998-12-16
NO931766L (no) 1993-05-14
AU655612B2 (en) 1995-01-05
IL99905A0 (en) 1992-08-18
FI932212L (fi) 1993-05-14
JP3493434B2 (ja) 2004-02-03

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